- The IGF-I receptor in cancer researchR Baserga
Kimmel Cancer Center, Thomas Jefferson University, 233 S 10th Street, 624 BLSB, Philadelphia, Pennsylvania, 19107, USA
Exp Cell Res 253:1-6. 1999..However, the IGF-IR can also induce differentiation, and eventually cell death, of certain types of cells. Its major substrates, IRS-1 and Shc, determine whether the IGF-IR will transform cells or will cause their differentiation...
- Differentiation and malignant transformation: two roads diverged in a woodR Baserga
Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
J Cell Biochem . 1999..The type 1 insulin-like growth factor receptor will serve as the paradigm for this review. J. Cell. Biochem. Suppls. 32/33:68-75, 1999...