Robert J Thoma

Summary

Country: USA

Publications

  1. ncbi request reprint Lateralization of auditory sensory gating and neuropsychological dysfunction in schizophrenia
    Robert J Thoma
    Psychiatry Service, Department of Radiology, New Mexico VA Health Care System, VAMC 116A, 1501 San Pedro SE, Albuquerque, NM 87108, USA
    Am J Psychiatry 160:1595-605. 2003
  2. ncbi request reprint M50 sensory gating predicts negative symptoms in schizophrenia
    Robert J Thoma
    Psychiatry Service, New Mexico VA Health Care System, Albuquerque, NM 87108, United States
    Schizophr Res 73:311-8. 2005
  3. pmc Impaired secondary somatosensory gating in patients with schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
    Psychiatry Res 151:189-99. 2007
  4. pmc Cognitive abilities and 50- and 100-msec paired-click processes in schizophrenia
    Ashley K Smith
    Center for Functional Brain Imaging, New Mexico VA Health Care System, 1501 San Pedro Drive S E, Albuquerque, NM 87108, USA
    Am J Psychiatry 167:1264-75. 2010
  5. pmc Schizophrenia diagnosis and anterior hippocampal volume make separate contributions to sensory gating
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Psychophysiology 45:926-35. 2008
  6. ncbi request reprint Efficacy of olanzapine and risperidone in schizophrenia: a randomized double-blind crossover design
    Jose M Canive
    Psychiatry Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Psychopharmacol Bull 39:105-16. 2006
  7. ncbi request reprint A specific test of hippocampal deficit in schizophrenia
    Faith M Hanlon
    Department of Psychiatry, New Mexico Veterans Affairs Health Care System, University of New Mexico, Albuquerque, NM 87131, USA
    Behav Neurosci 119:863-75. 2005
  8. ncbi request reprint Distinct M50 and M100 auditory gating deficits in schizophrenia
    Faith M Hanlon
    Center for Functional Brain Imaging, New Mexico VA Health Care System, Albuquerque, New Mexico 87108, USA
    Psychophysiology 42:417-27. 2005
  9. doi request reprint Bilateral hippocampal dysfunction in schizophrenia
    Faith M Hanlon
    The MIND Research Network, Pete and Nancy Domenici Hall, 1101 Yale Blvd NE, Albuquerque, NM 87106, USA
    Neuroimage 58:1158-68. 2011
  10. ncbi request reprint Impairment on the hippocampal-dependent virtual Morris water task in schizophrenia
    Faith M Hanlon
    The Mental Illness and Neuroscience Discovery MIND Institute, 1101 Yale Blvd NE, Albuquerque, New Mexico 87106, USA
    Schizophr Res 87:67-80. 2006

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Lateralization of auditory sensory gating and neuropsychological dysfunction in schizophrenia
    Robert J Thoma
    Psychiatry Service, Department of Radiology, New Mexico VA Health Care System, VAMC 116A, 1501 San Pedro SE, Albuquerque, NM 87108, USA
    Am J Psychiatry 160:1595-605. 2003
    ....
  2. ncbi request reprint M50 sensory gating predicts negative symptoms in schizophrenia
    Robert J Thoma
    Psychiatry Service, New Mexico VA Health Care System, Albuquerque, NM 87108, United States
    Schizophr Res 73:311-8. 2005
    ..This finding is compatible with information processing theories of negative symptoms and with more recent findings of fronto-temporal abnormality in patients with predominantly negative symptoms...
  3. pmc Impaired secondary somatosensory gating in patients with schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
    Psychiatry Res 151:189-99. 2007
    ..Patients demonstrated no impairment in SI gating, but a robust gating deficit in SII, supporting the presence of cross modal gating deficits in schizophrenia...
  4. pmc Cognitive abilities and 50- and 100-msec paired-click processes in schizophrenia
    Ashley K Smith
    Center for Functional Brain Imaging, New Mexico VA Health Care System, 1501 San Pedro Drive S E, Albuquerque, NM 87108, USA
    Am J Psychiatry 167:1264-75. 2010
    ..In addition, the functional implications remain unclear. In the present study, EEG and magnetoencephalography (MEG) were used to examine paired-click measures and cognitive correlates of paired-click activity...
  5. pmc Schizophrenia diagnosis and anterior hippocampal volume make separate contributions to sensory gating
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Psychophysiology 45:926-35. 2008
    ..Schizophrenia diagnosis predicted M50 gating independent of hippocampal volume. These results are consistent with the finding that hippocampus is a critical part of a fronto-temporal circuit involved in auditory gating...
  6. ncbi request reprint Efficacy of olanzapine and risperidone in schizophrenia: a randomized double-blind crossover design
    Jose M Canive
    Psychiatry Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Psychopharmacol Bull 39:105-16. 2006
    ..Despite the small number of subjects, this study shows the potential of a within-subject design to elucidate differences in efficacy...
  7. ncbi request reprint A specific test of hippocampal deficit in schizophrenia
    Faith M Hanlon
    Department of Psychiatry, New Mexico Veterans Affairs Health Care System, University of New Mexico, Albuquerque, NM 87131, USA
    Behav Neurosci 119:863-75. 2005
    ..Patients' abnormal hippocampal lateralization may play a role in the hippocampal-dependent behavioral deficit...
  8. ncbi request reprint Distinct M50 and M100 auditory gating deficits in schizophrenia
    Faith M Hanlon
    Center for Functional Brain Imaging, New Mexico VA Health Care System, Albuquerque, New Mexico 87108, USA
    Psychophysiology 42:417-27. 2005
    ..In contrast, a right-hemisphere M100 gating deficit was unrelated to M50 gating in either hemisphere. Investigations of interhemisphere gating relations may clarify group differences in regional connectivity and their role in gating...
  9. doi request reprint Bilateral hippocampal dysfunction in schizophrenia
    Faith M Hanlon
    The MIND Research Network, Pete and Nancy Domenici Hall, 1101 Yale Blvd NE, Albuquerque, NM 87106, USA
    Neuroimage 58:1158-68. 2011
    ..These data demonstrate the capacity to assess lateralized hippocampal function and suggest a bilateral hippocampal behavioral and activation deficit in schizophrenia...
  10. ncbi request reprint Impairment on the hippocampal-dependent virtual Morris water task in schizophrenia
    Faith M Hanlon
    The Mental Illness and Neuroscience Discovery MIND Institute, 1101 Yale Blvd NE, Albuquerque, New Mexico 87106, USA
    Schizophr Res 87:67-80. 2006
    ..There was no deficit in the visible-platform condition. These findings identify a behavioral impairment on a hippocampal-dependent task in schizophrenia and support using the MWT in testing animal models of schizophrenia...
  11. ncbi request reprint Neuropsychological and sensory gating deficits related to remote alcohol abuse history in schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    J Int Neuropsychol Soc 12:34-44. 2006
    ....
  12. pmc Adolescent substance abuse: the effects of alcohol and marijuana on neuropsychological performance
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, 87131, USA
    Alcohol Clin Exp Res 35:39-46. 2011
    ....
  13. doi request reprint Lateralized abnormalities in auditory M50 sensory gating and cortical thickness of the superior temporal gyrus in post-traumatic stress disorder: preliminary results
    Michael Hunter
    New Mexico VA Healthcare System Clinical Neuroscience Research Program, Albuquerque, NM, USA
    Psychiatry Res 191:138-44. 2011
    ..These findings suggest that the structural integrity of right hemisphere STG cortices play an important role in auditory sensory gating deficits in PTSD...
  14. ncbi request reprint A non-invasive method for observing hippocampal function
    Faith M Hanlon
    New Mexico VA Health Care System, 1501 San Pedro Drive, SE Albuquerque, NM 87108, USA
    Neuroreport 14:1957-60. 2003
    ..Patients with unilateral hippocampal damage showed activation in undamaged hippocampus. MEG during transverse patterning performance is a promising, non-invasive tool for assessing hippocampal function...
  15. ncbi request reprint Visual processing of facial affect
    Stephen Lewis
    Department of Psychiatry, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA
    Neuroreport 14:1841-5. 2003
    ..These findings are considered in the context of a specialized neural face-dependent information system...
  16. pmc The impact of developmental instability on Voxel-Based Morphometry analyses of neuroanatomical abnormalities in schizophrenia
    Matthew Euler
    Department of Psychology, University of New Mexico, Albuquerque, NM 87131, USA
    Schizophr Res 115:1-7. 2009
    ..These results support the DI approach and suggest that the unique etiologic factors associated with schizophrenia lead to widespread gray matter volume reductions...
  17. ncbi request reprint A parietal-frontal network studied by somatosensory oddball MEG responses, and its cross-modal consistency
    Ming Xiong Huang
    Department of Radiology, University of California, San Diego, 92103 8756, USA
    Neuroimage 28:99-114. 2005
    ....
  18. pmc Neurometabolite concentration and clinical features of chronic alcohol use: a proton magnetic resonance spectroscopy study
    Ronald A Yeo
    Department of Psychology, University of New Mexico, Albuquerque, NM, USA
    Psychiatry Res 211:141-7. 2013
    ..These results suggest that the nature of neurometabolite abnormalities in chronic heavy drinkers may vary as a function of duration of abuse...
  19. ncbi request reprint Dynamic neural activity recorded from human amygdala during fear conditioning using magnetoencephalography
    Sandra N Moses
    Department of Psychology, University of New Mexico, Albuquerque, NM 87109, USA
    Brain Res Bull 71:452-60. 2007
    ..The amygdala also shows stimulus omission-related activation that could potentially provide feedback about experienced stimulus contingencies to modify future responding during learning and extinction...
  20. pmc Hippocampus volume and episodic memory in schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, USA
    J Int Neuropsychol Soc 15:182-95. 2009
    ..In this sample of adults with schizophrenia, atypical relationships between regional hippocampus volumes and episodic memory ability were found, as was an atypical negative association between hippocampus volume and age...
  21. pmc Diffusion tensor imaging of white matter networks in individuals with current and remitted alcohol use disorders and comorbid conditions
    Mollie A Monnig
    Department of Psychology, University of New Mexico, Albuquerque, NM87131, USA
    Psychol Addict Behav 27:455-65. 2013
    ....
  22. pmc Resting state and task-induced deactivation: A methodological comparison in patients with schizophrenia and healthy controls
    Maggie V Mannell
    The MIND Research Network, Albuquerque, New Mexico, USA
    Hum Brain Mapp 31:424-37. 2010
    ..The increased posterior and reduced anterior connectivity may partially explain some of the cognitive dysfunction and clinical symptoms that are frequently associated with schizophrenia...
  23. ncbi request reprint Developmental instability and the neural dynamics of the speed-intelligence relationship
    Robert J Thoma
    Center for Neuropsychological Services, Department of Psychiatry, 915 Vassar NE, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Neuroimage 32:1456-64. 2006
    ..These observations suggest that fluid intelligence is primarily related to speed during processing associated with decision time, while fluctuating asymmetry predicted slower processing across all stages of information processing...
  24. pmc Rare copy number deletions predict individual variation in human brain metabolite concentrations in individuals with alcohol use disorders
    Ronald A Yeo
    Department of Psychology, University of New Mexico, Albuquerque, New Mexico, USA
    Biol Psychiatry 70:537-44. 2011
    ..The current study investigated the importance of a specific type of genetic mutation, copy number variation (CNV), for neurometabolite concentrations in a bilateral anterior cingulate voxel...
  25. pmc The impact of copy number deletions on general cognitive ability and ventricle size in patients with schizophrenia and healthy control subjects
    Ronald A Yeo
    Department of Psychology, University of New Mexico, Albuquerque, New Mexico, USA
    Biol Psychiatry 73:540-5. 2013
    ..Individual variation in a specific type of mutation, uncommon genetic deletions, has recently been linked with both general cognitive ability and risk for schizophrenia...
  26. pmc White matter volume in alcohol use disorders: a meta-analysis
    Mollie A Monnig
    Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Boulevard SE, Albuquerque, NM 87106, USA
    Addict Biol 18:581-92. 2013
    ..These results are suggestive of WM recovery with sustained abstinence and point to the need for further investigation of factors related to treatment-seeking status...
  27. ncbi request reprint Abnormal stimulus-response intensity functions in posttraumatic stress disorder: an electrophysiological investigation
    Jeffrey David Lewine
    Departments of Psychology and Psychiatry, University of New Mexico, Albuquerque, NM, USA
    Am J Psychiatry 159:1689-95. 2002
    ....
  28. pmc Superior temporal gyrus spectral abnormalities in schizophrenia
    J Christopher Edgar
    Department of Psychology, Beckman Institute Biomedical Imaging Center, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Psychophysiology 45:812-24. 2008
    ..Compared to controls, patients with schizophrenia showed more low-frequency phase variability, and the decreased 100-ms S1 evoked response observed in patients was best predicted by the STG phase-locking measure...
  29. ncbi request reprint Cross-modal generality of the gating deficit
    J Christopher Edgar
    Department of Psychology and Beckman Institute Biomedical Imaging Center, University of Illinois at Urbana Champaign, Urbana, IL 61820, USA
    Psychophysiology 42:318-27. 2005
    ..Patients showed abnormal auditory M50 gating but normal somatosensory M20 gating. Results argue against a cross-modal gating deficit in primary somatosensory cortex...