Marie Ange Thelu
- Prevalence and impact of occult hepatitis B infection in chronic hepatitis C patients treated with pegylated interferon and ribavirinMarion Levast
Laboratory of Virology, Grenoble University Hospital, Grenoble, France
J Med Virol 82:747-54. 2010..This, just as anti-HBC status, had no clinical impact in a large cohort of hepatitis C patients. It therefore does not appear useful to screen for occult hepatitis B in these patients with this test before beginning HCV treatment...
- Lack of clinical significance of variability in the internal ribosome entry site of hepatitis C virusMarie Ange Thelu
Département d Hépato Gastroentérologie, Hopital Albert Michallon, Grenoble, France
J Med Virol 72:396-405. 2004..Variations observed in the IRES are not a parameter of response to antiviral therapy, but the integrity of this region is a necessary condition to maintain its activity...
- Characterization and role of intra-hepatic regulatory T cells in chronic hepatitis C pathogenesisNathalie Sturm
INSERM, Unité 823, Grenoble, France
J Hepatol 53:25-35. 2010..In vitro data point out that regulatory T cells (Treg) are able to suppress HCV-specific lymphocyte proliferation and cytokine secretion but their implication in this pathology is still debated...