Research Topics
| Athena ZuppaSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Prescribing habits and caregiver satisfaction with resources for dosing children: rationale for more informative dosing guidanceJeffrey S Barrett
Department of Pediatrics, Division of Clinical Pharmacology and Therapeutics, The Children s Hospital of Philadelphia, 3501 Civic Center Blvd, Philadelphia, PA 19104, USA
BMC Pediatr 11:25. 2011....
Understanding renal replacement therapy and dosing of drugs in pediatric patients with kidney diseaseAthena F Zuppa
Department of Anesthesia and Critical Care Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4318, USA
J Clin Pharmacol 52:134S-40S. 2012..Furthermore, the pediatric patient presents additional concerns because of developmental factors in children that affect both pharmacokinetics of drugs...- Population pharmacokinetics of ketorolac in neonates and young infantsAthena F Zuppa
Division of Clinical Pharmacology and Therapeutics, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Am J Ther 16:143-6. 2009..The clearance values in these neonates and younger group of infants are greater than that reported for older children and adults... - Pharmacokinetics and pharmacodynamics in the critically ill childAthena F Zuppa
The Children s Hospital of Philadelphia, Abramson Research Center, 3516 Civic Center Boulevard, Suite 916 H, Philadelphia, PA 19104, USA
Pediatr Clin North Am 55:735-55, xii. 2008..Many medications are prescribed for children based on dosing guidance from adult studies, however. Care providers must be cautious of the high risk for drug interactions and adverse reactions in the intensive care setting... 
An informatics approach to assess pediatric pharmacotherapy: design and implementation of a hospital drug utilization systemAthena Zuppa
Clinical Pharmacology and Therapeutics, Abramson Research Center, Suite 916 J, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
J Clin Pharmacol 47:1172-80. 2007..The creation of a national or even global drug utilization network would facilitate the examination of geographical and/or socioeconomic influences in drug utilization and prescribing practices in general...- Population pharmacokinetics of milrinone in neonates with hypoplastic left heart syndrome undergoing stage I reconstructionAthena F Zuppa
Division of Clinical Pharmacology and Therapeutics, Department of Pediatrics, Abramson Research Center, Philadelphia, Pennsylvania 19104 4318, USA
Anesth Analg 102:1062-9. 2006..6 mL x kg(-1) x min(-1)) by postoperative day 4. In the postoperative setting of markedly impaired renal function, an infusion rate of 0.2 microg x kg(-1) x min(-1) should be considered... - The effect of a thyroid hormone infusion on vasopressor support in critically ill children with cessation of neurologic functionAthena F Zuppa
Department of Anesthesia and Critical Care Medicine, Division of Critical Care Medicine, Children s Hospital of Philadelphia, USA
Crit Care Med 32:2318-22. 2004..To determine the impact of a thyroid hormone infusion (T4) on the vasopressor requirements in children with cessation of neurologic function (i.e., brain death) during evaluation for organ recovery.. - Sensitive and specific liquid chromatography-tandem mass spectrometric method for the quantitation of dexmedetomidine in pediatric plasmaJames I Lee
Division of Clinical Pharmacology and Therapeutics, Department of Pediatrics, Abramson Research Center 916H, Philadelphia, PA 19104 4399, USA
J Chromatogr B Analyt Technol Biomed Life Sci 852:195-201. 2007..This method is robust and has been successfully employed in a pharmacokinetic study of Dex in infants postoperative from cardiac surgery... - Population pharmacokinetics of dexmedetomidine in infants after open heart surgeryFelice Su
Division of Clinical Pharmacology and Therapeutics, Abramson Research Center, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Anesth Analg 110:1383-92. 2010..Only limited pharmacokinetic data are available for pediatric patients. The primary aim of this study was to determine the pharmacokinetics of dexmedetomidine in infants after open heart surgery... - Application of Individualized Bayesian Urea Kinetic Modeling to pediatric hemodialysisOlivera Marsenic
Laboratory for Applied PK PD, Division of Clinical Pharmacology and Therapeutics, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
ASAIO J 56:246-53. 2010..This study suggests that the IBKM can be used in a pediatric HD setting and accurately predict Ceq in children using only pre-HD and immediately post-HD BUN... - Drug utilization in the pediatric intensive care unit: monitoring prescribing trends and establishing prioritization of pharmacotherapeutic evaluation of critically ill childrenAthena F Zuppa
Department of Pediatrics, Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Clin Pharmacol 45:1305-12. 2005.... - Untying the Gordian knotFelice Su
Anesth Analg 104:993; author reply 993-4. 2007 - Propofol pharmacokineticsAthena F Zuppa
Pediatr Crit Care Med 4:124-5. 2003
Research Grants
- Improving Drug Development for the Critically Ill ChildAthena Zuppa; Fiscal Year: 2007..This intensive didactic and mentored training will allow for the development of a future independent pediatric clinical investigator. ..
- Impact of Pharmacology on Duration of Ventilation in Patients with Resp FailureAthena F Zuppa; Fiscal Year: 2010....