Chaolin Zhang

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
    Chaolin Zhang
    Laboratory of Molecular Neuro Oncology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA
    Nat Biotechnol 29:607-14. 2011
  2. ncbi Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
    Chaolin Zhang
    Laboratory of Molecular Neuro Oncology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 329:439-43. 2010
  3. ncbi Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
    Donny D Licatalosi
    Laboratory of Molecular Neuro Oncology, The Rockefeller University, New York, New York 10065, USA
    Genes Dev 26:1626-42. 2012
  4. ncbi Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
    Gulayse Ince-Dunn
    Laboratory of Molecular Neuro Oncology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Neuron 75:1067-80. 2012
  5. ncbi NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure
    Taesun Eom
    Laboratory of Molecular Neuro Oncology, Rockefeller University, New York, United States
    elife 2:e00178. 2013
  6. ncbi FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
    Jennifer C Darnell
    Laboratory of Molecular Neuro Oncology, The Rockefeller University, New York, NY 10065, USA
    Cell 146:247-61. 2011

Collaborators

Detail Information

Publications6

  1. ncbi Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
    Chaolin Zhang
    Laboratory of Molecular Neuro Oncology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA
    Nat Biotechnol 29:607-14. 2011
    ..CIMS analysis provides a general and more precise means of mapping protein-RNA interactions than currently available methods and insight into the biochemical properties of such interactions in living tissues...
  2. ncbi Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
    Chaolin Zhang
    Laboratory of Molecular Neuro Oncology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 329:439-43. 2010
    ..Thus, we have developed a general approach to understanding mammalian RNA regulation at the systems level...
  3. ncbi Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
    Donny D Licatalosi
    Laboratory of Molecular Neuro Oncology, The Rockefeller University, New York, New York 10065, USA
    Genes Dev 26:1626-42. 2012
    ..Thus, Ptbp2 inhibition of a discrete set of adult neuronal exons underlies early brain development prior to neuronal differentiation and is essential for postnatal survival...
  4. ncbi Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
    Gulayse Ince-Dunn
    Laboratory of Molecular Neuro Oncology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Neuron 75:1067-80. 2012
    ..The genome-wide analysis of nElavl targets reveals that one function of neuron-specific RNABPs is to control excitation-inhibition balance in the brain...
  5. ncbi NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure
    Taesun Eom
    Laboratory of Molecular Neuro Oncology, Rockefeller University, New York, United States
    elife 2:e00178. 2013
    ..The data reveal a hidden means of dynamic RNA regulation linking electrical activity to splicing and protein output, and of mediating homeostatic excitation/inhibition balance in neurons.DOI:http://dx.doi.org/10.7554/eLife.00178.001...
  6. ncbi FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
    Jennifer C Darnell
    Laboratory of Molecular Neuro Oncology, The Rockefeller University, New York, NY 10065, USA
    Cell 146:247-61. 2011
    ..In addition, they provide insight into the molecular basis of the cognitive and allied defects in FXS and ASD and suggest multiple targets for clinical intervention...