Research Topics
| BABETTE S contact ZEMELSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Bone mineral accretion and its relationship to growth, sexual maturation and body composition during childhood and adolescenceBabette Zemel
Division of Gastroenterology, Hepatology and Nutrition, Children s Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
World Rev Nutr Diet 106:39-45. 2013..Understanding these complex relationships is essential to understanding bone metabolism during this part of the life cycle and the challenges of assessing bone health in children with medical conditions that threaten bone health...
Effect of zinc supplementation on growth and body composition in children with sickle cell diseaseBabette S Zemel
Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, 19104 4399, USA
Am J Clin Nutr 75:300-7. 2002..Poor growth and delayed maturation in children with sickle cell disease (SCD) may be due, in part, to mild zinc deficiency...
Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in childrenBabette S Zemel
The Children s Hospital of Philadelphia, 3535 Market Street, Room 1560, Philadelphia, Pennsylvania 19104, USA
J Clin Endocrinol Metab 95:1265-73. 2010..Adjustments using HAZ were least biased relative to HAZ and age and can be used to evaluate the effect of short or tall stature on BMC/BMD Z-scores...- The recognition and treatment of growth disorders - a 50-year retrospectiveBabette Zemel
Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Department of Pediatrics, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Ann Hum Biol 36:496-510. 2009..These examples accentuate the need for continued participation of human biologists in the study of growth and development and the care of children... - Revised pediatric reference data for the lateral distal femur measured by Hologic Discovery/Delphi dual-energy X-ray absorptiometryBabette S Zemel
Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
J Clin Densitom 12:207-18. 2009.... - Peripheral quantitative computed tomography in children and adolescents: the 2007 ISCD Pediatric Official PositionsBabette Zemel
The Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
J Clin Densitom 11:59-74. 2008..Reference data that sufficiently characterize the normal range of variability in the population also need to be established... - Effects of delayed pubertal development, nutritional status, and disease severity on longitudinal patterns of growth failure in children with sickle cell diseaseBabette S Zemel
Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Pediatr Res 61:607-13. 2007..Growth failure and maturational delay remain significant chronic problems in children with SCD-SS and are related to potentially modifiable factors such as nutritional status... - Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: results of the bone mineral density in childhood studyBabette S Zemel
Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
J Clin Endocrinol Metab 96:3160-9. 2011..Deficits in bone acquisition during growth may increase fracture risk. Assessment of bone health during childhood requires appropriate reference values relative to age, sex, and population ancestry to identify bone deficits... - Quantitative computed tomography and computed tomography in childrenBabette S Zemel
Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
Curr Osteoporos Rep 9:284-90. 2011..These new studies will ultimately help us understand the development of sex differences in bone strength that emerge in adolescence... - Evaluation of formulas for calculating total energy requirements of preadolescent children with cystic fibrosisJillian Trabulsi
Divisions of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Am J Clin Nutr 85:144-51. 2007..Care providers use one of several empirically derived formulas to calculate energy requirements, yet the validity of these formulas has seldom been tested... - Rethinking growth failure in Alagille syndrome: the role of dietary intake and steatorrheaAlisha J Rovner
Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA
J Pediatr Gastroenterol Nutr 35:495-502. 2002..Intervention studies to increase energy and nutrient intake are needed to determine the effect of improved dietary intake on growth and nutritional status of children with AGS... - Bone area and bone mineral content deficits in children with sickle cell diseaseAnne M Buison
Division of Gastroenterology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatrics 116:943-9. 2005..CONCLUSIONS: Children with SCD-SS have significant deficits in WBBMC that persist despite adjustment for poor growth and decreased lean mass. These children may be at increased risk for fragility fractures and suboptimal peak bone mass... - Fecal elastase: pancreatic status verification and influence on nutritional status in children with cystic fibrosisJacqueline R Cohen
Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, Pennsylvania, USA
J Pediatr Gastroenterol Nutr 40:438-44. 2005..Children with residual FE had greater fat absorption and improved growth and nutritional status over 24 months. FE assessment should be used to verify pancreatic status in patients with cystic fibrosis... - Divergent effects of glucocorticoids on cortical and trabecular compartment BMD in childhood nephrotic syndromeRachel J Wetzsteon
Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
J Bone Miner Res 24:503-13. 2009..Lower bone biomarkers were associated with greater cortical vBMD. Studies are needed to determine the fracture implications of these varied effects... - Vitamin B6 status of children with sickle cell diseaseMelissa C Nelson
Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 4399, USA
J Pediatr Hematol Oncol 24:463-9. 2002..The purpose of this study was to assess vitamin B(6) status of children with SCD-SS ages 3 to 20 years and determine its relationship to growth, dietary intake, and disease severity... - Interactions between growth and body composition in children treated with high-dose chronic glucocorticoidsBethany J Foster
Department of Pediatrics, Division of Nephrology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, USA
Am J Clin Nutr 80:1334-41. 2004..However, despite prolonged, repeated courses of glucocorticoid, children with steroid-sensitive nephrotic syndrome (SSNS) have almost normal adult height. Little information exists on body composition... - Self-assessment of sexual maturity status in children with Crohn's diseaseJoan I Schall
Division of Gastroenterology and Nutrition, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Pediatr 141:223-9. 2002..CONCLUSIONS: Self-assessment of SMS was a reliable and valid method in children with CD and is useful in screening for maturational delay in children with chronic disease... - Bone mineral content deficits of the spine and whole body in children at time of diagnosis with celiac diseaseMuralidhar Jatla
Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA
J Pediatr Gastroenterol Nutr 48:175-80. 2009..The secondary aim was to examine the effect of histological grade on BMC... - Low vitamin D status in children with sickle cell diseaseAnne M Buison
Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania, 19104, USA
J Pediatr 145:622-7. 2004..05). CONCLUSIONS: Low serum vitamin D status was highly prevalent in black children with SCD-SS. Vitamin D status was associated with season and dietary intake... - Risk factors for low serum 25-hydroxyvitamin D concentrations in otherwise healthy children and adolescentsFrancis L Weng
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am J Clin Nutr 86:150-8. 2007..Serum 25-hydroxyvitamin D [25(OH)D] concentrations serve as a biomarker for vitamin D stores. Prior studies have not examined the risk factors for low vitamin D concentrations in a multiethnic sample of US youth across a broad age range... - Infant weight gain and childhood overweight status in a multicenter, cohort studyNicolas Stettler
The Children s Hospital of Philadelphia, Division of Gastroenterology and Nutrition, Philadelphia, Pennsylvania 19104 4399, USA
Pediatrics 109:194-9. 2002..To determine whether a rapid rate of weight gain in early infancy is associated with overweight status in childhood... - Resting energy expenditure is not increased in prepubertal children with Alagille syndromeAlisha J Rovner
Division of Gastroenterology and Nutrition at The Children's Hospital of Philadelphia, PA 19104, USA
J Pediatr 148:680-2. 2006..We evaluated 16 subjects with AGS and 37 healthy controls and did not find a significant difference in REE (101% +/- 12%, 105% +/- 13%, respectively)... - Hypovitaminosis D is associated with greater body mass index and disease activity in pediatric systemic lupus erythematosusTracey B Wright
Department of Pediatrics, Division of Rheumatology, University of Texas Southwestern Medical Center, Dallas, TX, USA
J Pediatr 155:260-5. 2009..To determine whether pediatric systemic lupus erythematosus (SLE) is associated with alterations in the vitamin D-parathyroid hormone (PTH) axis and to assess the relation between vitamin D deficiency and SLE activity... - Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's diseaseSarah E Dubner
Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Gastroenterology 136:123-30. 2009..The objective of this longitudinal study was to assess musculoskeletal outcomes in an incident cohort of children with CD using peripheral quantitative computed tomography (pQCT)... - Effects of sex, race, and puberty on cortical bone and the functional muscle bone unit in children, adolescents, and young adultsMary B Leonard
Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
J Clin Endocrinol Metab 95:1681-9. 2010..Sex and race differences in bone development are associated with differences in growth, maturation, and body composition... - Progressive bone mineral content loss in children with intractable epilepsy treated with the ketogenic dietA G Christina Bergqvist
Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Am J Clin Nutr 88:1678-84. 2008..The ketogenic diet (KD) is a high-fat, low-carbohydrate, and protein diet that effectively treats intractable epilepsy (IE)... - Clinical and genetic correlates of exercise performance in young children with cystic fibrosisMichael G McBride
Division of Cardiology, The Children s Hospital of Philadelphia, PA 19104, USA
Percept Mot Skills 110:995-1009. 2010..Rather, the extent of pulmonary disease and undernutrition were associated with functional performance... - Gender differences in body composition deficits at diagnosis in children and adolescents with Crohn's diseaseMeena Thayu
Children s Hospital of Philadelphia Gastroenterology, Hepatology, and Nutrition, Philadelphia, Pennsylvania 19104, USA
Inflamm Bowel Dis 13:1121-8. 2007..Objectives: To quantify LM and FM in incident pediatric CD subjects and controls, and to identify determinants of LM and FM deficits... - Adequacy of dietary intake declines with age in children with sickle cell diseaseDeborah A Kawchak
Nutrition and Growth Laboratory, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Am Diet Assoc 107:843-8. 2007..Dietary intake was particularly poor in adolescents. Efforts are needed to ensure dietary adequacy in children with sickle cell disease, type SS and to understand the etiology of poor dietary intake... - Vitamin A intake and elevated serum retinol levels in children and young adults with cystic fibrosisAsim Maqbool
Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Cyst Fibros 7:137-41. 2008..Individuals with cystic fibrosis (CF) and pancreatic insufficiency (PI) are at risk for fat-soluble vitamin deficiency, including vitamin A. Recent evidence suggests current practices of vitamin A intake results in elevated serum retinol... - Assessment of spine bone mineral density in juvenile idiopathic arthritis: impact of scan projectionSarah E Dubner
University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Clin Densitom 11:302-8. 2008..In conclusion, WA-BMD may be more sensitive to disease effects in children because it selectively measures the trabecular-rich vertebral body and is independent of growth-related changes in BMC of the dense spinous processes... - Observational study of bone accretion during successful weight loss in obese adolescentsNicolas Stettler
Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Obesity (Silver Spring) 16:96-101. 2008..To assess bone mineral content (BMC) among obese adolescents who lose weight during a critical period for bone accretion... - Energy expenditure in obesity associated with craniopharyngiomaRoy J Kim
Division of Endocrinology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Childs Nerv Syst 26:913-7. 2010..Obesity is a common yet incompletely understood complication of childhood craniopharyngioma. We hypothesized that craniopharyngioma is associated with specific defects in energy balance compared to obese control children... - Evidence-based practice recommendations for nutrition-related management of children and adults with cystic fibrosis and pancreatic insufficiency: results of a systematic reviewVirginia A Stallings
Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, 3535 Market St, Philadelphia, PA 19104, USA
J Am Diet Assoc 108:832-9. 2008..These Registry data-based recommendations are presented... - Serum linoleic acid status as a clinical indicator of essential fatty acid status in children with cystic fibrosisAsim Maqbool
Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Pediatr Gastroenterol Nutr 47:635-44. 2008..Children with cystic fibrosis (CF) and pancreatic insufficiency (PI) are at increased risk for essential fatty acid (EFA) deficiency... - Deficits in bone mineral content in children and adolescents with cystic fibrosis are related to height deficitsAndrea Kelly
Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Clin Densitom 11:581-9. 2008..BMC deficits are related to altered body size, reduced LBM, and pulmonary function in children with CF. Interventions targeting improved growth, muscle mass, and pulmonary function may benefit bone health in CF... - Interpretation of biomarkers of bone metabolism in children: impact of growth velocity and body size in healthy children and chronic diseaseShamir Tuchman
Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr 153:484-90. 2008.... - Bone density, structure, and strength in juvenile idiopathic arthritis: importance of disease severity and muscle deficitsJon M Burnham
Children s Hospital of Philadelphia, and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Arthritis Rheum 58:2518-27. 2008.... - Determinants of changes in linear growth and body composition in incident pediatric Crohn's diseaseMeena Thayu
Department of Pediatrics, The Children s Hospital of Philadelphia, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Gastroenterology 139:430-8. 2010..Pediatric Crohn's disease (CD) is associated with growth, lean mass (LM), and fat mass (FM) deficits. This study assessed and identified determinants of changes in height and body composition in children with CD following... - Alterations in proximal femur geometry in children treated with glucocorticoids for Crohn disease or nephrotic syndrome: impact of the underlying diseaseJon M Burnham
The Children s Hospital of Philadelphia, Philadelphia PA 19104, USA
J Bone Miner Res 22:551-9. 2007..Subperiosteal width and section modulus were significantly lower in CD and greater in SSNS compared with controls, highlighting the importance of the underlying disease, persistent inflammation, and alterations in lean mass... - Body composition of children aged 1 to 12 years with biliary atresia or Alagille syndromeJessica L Arvay
The Division of Gastroenterology and Nutrition, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
J Pediatr Gastroenterol Nutr 40:146-50. 2005..To optimize nutritional management of these conditions it is essential to understand the normal growth characteristics... - Body-composition alterations consistent with cachexia in children and young adults with Crohn diseaseJon M Burnham
Department of Pediatrics, Division of Rheumatology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Am J Clin Nutr 82:413-20. 2005..Crohn disease (CD) in children is associated with low body mass index (BMI), poor growth, and delayed maturation; alterations in lean and fat mass, however, are poorly characterized... - Adolescent development and energy expenditure in females with cystic fibrosisVirginia A Stallings
Department of Pediatrics, Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Clin Nutr 24:737-45. 2005..Relationships between sexual maturity, nutrition, resting energy expenditure (REE), and pulmonary status in females with CF and pancreatic insufficiency (PI) were evaluated... - Mild to moderate cystic fibrosis is not associated with increased fracture risk in children and adolescentsAlisha J Rovner
Division of Gastroenterology, The Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Pediatr 147:327-31. 2005..96, 95% CI: 0.68, 1.30, P = .82). CONCLUSION: Children and adolescents with CF, PI, and mild-to-moderate lung disease were not at an increased risk of fracture... - Statistical validation of air-displacement plethysmography for body composition assessment in childrenRichard F Ittenbach
Biostatistics and Data Management Core, University of Pennsylvania School of Medicine, PA 19104, USA
Ann Hum Biol 33:187-201. 2006..Existing validation studies of air-displacement plethysmography (ADP) have been based on small, narrowly defined samples, using simple linear regression or Bland-Altman analyses... - Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndromeMary B Leonard
Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
N Engl J Med 351:868-75. 2004..We determined the effects of long-term treatment with glucocorticoids on bone mineral content in children with glucocorticoid-sensitive nephrotic syndrome, a disorder with minimal known independent effects on bone... - Obesity during childhood and adolescence augments bone mass and bone dimensionsMary B Leonard
Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia PA 19104, USA
Am J Clin Nutr 80:514-23. 2004..Studies of the effect of childhood obesity on bone accrual during growth have yielded conflicting results, largely related to the failure to adequately characterize the confounding effects of growth, maturation, and body composition... - Plasma zinc and growth status in preadolescent children with cystic fibrosisAsim Maqbool
Divisions of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Pediatr Gastroenterol Nutr 43:95-101. 2006..To investigate plasma zinc status in relation to dietary and supplemental zinc intake, growth and pulmonary status in preadolescent children with cystic fibrosis (CF) and pancreatic insufficiency (PI)... - Vitamin A status, hospitalizations, and other outcomes in young children with sickle cell diseaseJoan I Schall
Division of Gastroenterology and Nutrition, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
J Pediatr 145:99-106. 2004..To determine the relation of serum vitamin A status to growth, nutritional and hematologic status, and to the number of hospitalizations in children with sickle cell disease-SS (homozygous for the S allele, SCD-SS)... - Elevated vitamin A intake and serum retinol in preadolescent children with cystic fibrosisRose C Graham-Maar
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
Am J Clin Nutr 84:174-82. 2006..Long-standing vitamin A supplementation may increase the risk of vitamin A toxicity... - Current concepts in pediatric bone diseaseMary B Leonard
Department of Pediatrics, Departments of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Pediatr Clin North Am 49:143-73. 2002..Further research is needed to characterize these changes and their use in the assessment of bone health and fracture risk in children. Only then can the impact of treatment strategies be appreciated fully... - DXA estimates of vertebral volumetric bone mineral density in children: potential advantages of paired posteroanterior and lateral scansMary B Leonard
Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Clin Densitom 9:265-73. 2006..In conclusion, paired Hologic PA lateral scans may increase sensitivity to growth-related increases in trabecular BMC and density in the spine, with less bias due to magnification error... - Whole body BMC in pediatric Crohn disease: independent effects of altered growth, maturation, and body compositionJon M Burnham
Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
J Bone Miner Res 19:1961-8. 2004..Adjustment for lean mass eliminated the bone deficit in CD. Steroid exposure was associated with short stature but not bone deficits relative to height... - Energy balance and the accuracy of reported energy intake in preadolescent children with cystic fibrosisJillian Trabulsi
Division of Gastroenterology, The Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Am J Clin Nutr 84:523-30. 2006..Suboptimal growth and nutritional status are common among children with cystic fibrosis (CF) and pancreatic insufficiency (PI). A better understanding of energy balance is required to improve prevention and treatment of malnutrition... - Vitamin D status in children, adolescents, and young adults with Crohn diseaseTimothy A Sentongo
Division of Gastroenterology, Hepatology, and Nutrition, Children s Memorial Hospital, Northwestern University, Chicago, IL 60614, USA
Am J Clin Nutr 76:1077-81. 2002..Crohn disease (CD) and vitamin D deficiency are associated with decreased bone mineralization... - Vitamin E status in children with cystic fibrosis and pancreatic insufficiencyShirley H Huang
Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4399, USA
J Pediatr 148:556-559. 2006.... - Rapid weight gain during infancy and obesity in young adulthood in a cohort of African AmericansNicolas Stettler
Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 19104, USA
Am J Clin Nutr 77:1374-8. 2003..Obesity is increasing in the United States. Evidence-based prevention is a public health priority and should target well-defined risk factors and critical periods... - Methodological agreement between two-compartment body-composition methods in childrenAnne M Buison
Division of Gastroenterology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Am J Hum Biol 18:470-80. 2006..Further development of body-composition techniques for young children need to account for variability in age, gender, and level of fatness... - Vitamin D insufficiency in steroid-sensitive nephrotic syndrome in remissionFrancis L Weng
Renal Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Pediatr Nephrol 20:56-63. 2005..Children with remitted SSNS may benefit from routine measurement of 25(OH)D, but the clinical significance of low 25(OH)D in this population remains unclear... - Interpretation of whole body dual energy X-ray absorptiometry measures in children: comparison with peripheral quantitative computed tomographyMary B Leonard
Department of Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
Bone 34:1044-52. 2004..Therefore, normalizing whole body DXA bone area for height and BMC for height provided the best measures of bone dimensions and strength. DXA BMC normalized for bone area and lean mass were poor indicators of bone strength... - Quantifying calcium intake in school age children: development and validation of the Calcium Counts! food frequency questionnaireBabette S Zemel
Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, 3535 Market Street, Philadelphia, PA 19104, USA
Am J Hum Biol 22:180-6. 2010..The CCFFQ is especially well-suited as a tool to identify children with low calcium intakes... - Vitamin D insufficiency in children, adolescents, and young adults with cystic fibrosis despite routine oral supplementationAlisha J Rovner
Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Am J Clin Nutr 86:1694-9. 2007..Cystic fibrosis (CF) with pancreatic insufficiency is associated with poor absorption of fat and fat-soluble vitamins, including vitamin D. Pancreatic enzyme supplementation does not completely correct fat malabsorption in CF patients... - In vivo NMR microscopy allows short-term serial assessment of multiple skeletal implications of corticosteroid exposureMasaya Takahashi
Department of Radiology, University of Pennsylvania Medical Center, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA
Proc Natl Acad Sci U S A 99:4574-9. 2002..Finally, this work, which was performed on a clinical scanner, has implications for evaluating patients on high-dose steroid treatment... - Trabecular structure quantified with the MRI-based virtual bone biopsy in postmenopausal women contributes to vertebral deformity burden independent of areal vertebral BMDGlenn A Ladinsky
Division of Renal, Electrolytes and Hypertension, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
J Bone Miner Res 23:64-74. 2008.... - Incidence and risk factors for weight loss during dual HIV/hepatitis C virus therapyVincent Lo Re
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
J Acquir Immune Defic Syndr 44:344-50. 2007..Clinical observations suggest that patients with HIV/hepatitis C virus (HCV) may lose body weight during dual therapy, but this has not been confirmed analytically... - Body composition in children with sickle cell diseaseElizabeth M Barden
Department of Public Health, The Commonwealth of Massachusetts, Boston, USA
Am J Clin Nutr 76:218-25. 2002..These body-composition abnormalities suggest that the nutritional needs of the African American children with SCD were not being met... - Markers of bone turnover are associated with growth and development in young subjects with sickle cell anemiaEllen B Fung
Department of Hematology, The Children s Hospital and Research Center, Oakland, California, USA
Pediatr Blood Cancer 50:620-3. 2008..Markers of bone turnover correlated with growth velocity and pubertal development but not with changes in bone mass... - Sensitivity of dual x-ray absorptiometry to stature and reference data source in pediatric patients: comment on the article by Stewart et alJon M Burnham
Arthritis Rheum 50:2378-9; author reply 2379-80. 2004 - Deficits in size-adjusted bone mass in children with Alagille syndromeIrene E Olsen
Center for Epidemiology and Biostatistics and Division of Neonatology, Cincinnati Children's Hospital Medical Cente, The University of Cincinnati College of Medicine, Cincinnati, OH, USA
J Pediatr Gastroenterol Nutr 40:76-82. 2005..CONCLUSIONS: Children with AGS have deficits in bone size and bone mass relative to body size. Modifiable factors, such as treatment of malabsorption should be explored as an early focus of AGS care to prevent bone fragility... - Proximal femur bone geometry is appropriately adapted to lean mass in overweight children and adolescentsMoira A Petit
Department of Health Evaluation Sciences, Penn State University College of Medicine, 600 Centerview Drive, Suite 2200, A210, Hershey, PA 17033, USA
Bone 36:568-76. 2005..These geometric adaptations are consistent with the mechanostat hypothesis that bone strength adapts primarily to muscle forces, not to static loads represented by body weight... - Risk factors for glucocorticoid-induced obesity in children with steroid-sensitive nephrotic syndromeBethany J Foster
Department of Pediatrics, Division of Nephrology, Montreal Children s Hospital, McGill University School of Medicine, Montreal, Quebec, Canada
Pediatr Nephrol 21:973-80. 2006..003] in all subjects with remote glucocorticoid exposure (black and non-black). These results indicate that non-black race and increased maternal BMI are risk factors for glucocorticoid-induced obesity in subjects with recent exposure... - The bone mineral density in childhood study: bone mineral content and density according to age, sex, and raceHeidi J Kalkwarf
Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
J Clin Endocrinol Metab 92:2087-99. 2007..Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits... - High risk of vitamin D deficiency in children with sickle cell diseaseAlisha J Rovner
Division of Epidemiology, Statistics and Prevention, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD, USA
J Am Diet Assoc 108:1512-6. 2008..However, children with SCD-SS were at greater risk for vitamin D deficiency than healthy African-American children... - Brief report: parent perspectives of nutritional status and mealtime behaviors in children with sickle cell diseaseMonica J Mitchell
Cincinnati Children s Hospital Medical Center University of Cincinnati School of Medicine, Cincinnati, Ohio 45229, USA
J Pediatr Psychol 29:315-20. 2004..To qualitatively evaluate parent perspectives of eating problems, nutritional status, and the potential for nutritional intervention in children with sickle cell disease (SCD)... - Re: Prevalence of long bone fractures in pediatric inflammatory bowel diseaseAlisha J Rovner
J Pediatr Gastroenterol Nutr 45:269-71; author reply 271. 2007
Research Grants
- BUILDING BETTER BONES IN CHILDRENBabette Zemel; Fiscal Year: 2003..abstract_text> ..
- Genome Wide Association Study of Bone Mineral Accretion During ChildhoodBABETTE S contact ZEMEL; Fiscal Year: 2010....