Gunar K Zagars

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi request reprint Mortality after cure of testicular seminoma
    Gunar K Zagars
    Department of Radiation Oncology, Box 97, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 22:640-7. 2004
  2. ncbi request reprint Prognostic factors for disease-specific survival after first relapse of soft-tissue sarcoma: analysis of 402 patients with disease relapse after initial conservative surgery and radiotherapy
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 57:739-47. 2003
  3. ncbi request reprint Surgical margins and reresection in the management of patients with soft tissue sarcoma using conservative surgery and radiation therapy
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:2544-53. 2003
  4. doi request reprint Radiation therapy field extent for adjuvant treatment of axillary metastases from malignant melanoma
    Beth M Beadle
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 73:1376-82. 2009
  5. ncbi request reprint Retroperitoneal soft tissue sarcoma: an analysis of radiation and surgical treatment
    Matthew T Ballo
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:158-63. 2007
  6. ncbi request reprint Combined-modality therapy for patients with regional nodal metastases from melanoma
    Matthew T Ballo
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 64:106-13. 2006
  7. ncbi request reprint Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy: an analysis of 1225 patients
    Gunar K Zagars
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:2530-43. 2003
  8. ncbi request reprint Sequencing radiotherapy for soft tissue sarcoma when re-resection is planned
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Radiat Oncol Biol Phys 56:21-7. 2003
  9. ncbi request reprint Complications of combined modality treatment of primary lower extremity soft-tissue sarcomas
    Christopher P Cannon
    Department of Orthopaedic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230, USA
    Cancer 107:2455-61. 2006
  10. ncbi request reprint Preoperative vs. postoperative radiation therapy for soft tissue sarcoma: a retrospective comparative evaluation of disease outcome
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:482-8. 2003

Detail Information

Publications46

  1. ncbi request reprint Mortality after cure of testicular seminoma
    Gunar K Zagars
    Department of Radiation Oncology, Box 97, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 22:640-7. 2004
    ..To determine the incidence of potentially treatment-related mortality in long-term survivors of testicular seminoma treated by orchiectomy and radiation therapy (XRT)...
  2. ncbi request reprint Prognostic factors for disease-specific survival after first relapse of soft-tissue sarcoma: analysis of 402 patients with disease relapse after initial conservative surgery and radiotherapy
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 57:739-47. 2003
    ..To document the prognostic factors for survival of patients with soft-tissue sarcoma sustaining a first relapse after definitive treatment...
  3. ncbi request reprint Surgical margins and reresection in the management of patients with soft tissue sarcoma using conservative surgery and radiation therapy
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:2544-53. 2003
    ..The potential benefits of such reresection have not been documented adequately...
  4. doi request reprint Radiation therapy field extent for adjuvant treatment of axillary metastases from malignant melanoma
    Beth M Beadle
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 73:1376-82. 2009
    ....
  5. ncbi request reprint Retroperitoneal soft tissue sarcoma: an analysis of radiation and surgical treatment
    Matthew T Ballo
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:158-63. 2007
    ..To evaluate the clinical outcomes of patients with localized retroperitoneal soft tissue sarcoma (STS) treated with complete surgical resection and radiation...
  6. ncbi request reprint Combined-modality therapy for patients with regional nodal metastases from melanoma
    Matthew T Ballo
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 64:106-13. 2006
    ..To evaluate the outcome and patterns of failure for patients with nodal metastases from melanoma treated with combined-modality therapy...
  7. ncbi request reprint Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy: an analysis of 1225 patients
    Gunar K Zagars
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:2530-43. 2003
    ..Prognostic factors for patients with soft-tissue sarcoma who are treated with conservative surgery and radiation are documented poorly...
  8. ncbi request reprint Sequencing radiotherapy for soft tissue sarcoma when re-resection is planned
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Radiat Oncol Biol Phys 56:21-7. 2003
    ..To evaluate whether disease outcome for localized soft-tissue sarcoma (STS) excised before referral to a specialist center and there re-resected was influenced by the timing of radiation therapy (XRT)-before or after re-resection...
  9. ncbi request reprint Complications of combined modality treatment of primary lower extremity soft-tissue sarcomas
    Christopher P Cannon
    Department of Orthopaedic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230, USA
    Cancer 107:2455-61. 2006
    ..Correlations between various patient, tumor, and treatment characteristics and complications in patients undergoing combined modality treatment for primary lower extremity soft-tissue sarcomas were investigated...
  10. ncbi request reprint Preoperative vs. postoperative radiation therapy for soft tissue sarcoma: a retrospective comparative evaluation of disease outcome
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:482-8. 2003
    ..However, there is little evidence regarding the relative effectiveness of preoperative vs. postoperative XRT. This retrospective study addresses the relative effectiveness of disease control by these two treatment sequences...
  11. ncbi request reprint Phase I trial of preoperative doxorubicin-based concurrent chemoradiation and surgical resection for localized extremity and body wall soft tissue sarcomas
    Peter W T Pisters
    Multidisciplinary Sarcoma Center, Department of Biostatistics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030 4009, USA
    J Clin Oncol 22:3375-80. 2004
    ....
  12. ncbi request reprint Excellent local control rates and distinctive patterns of failure in myxoid liposarcoma treated with conservation surgery and radiotherapy
    B Ashleigh Guadagnolo
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 70:760-5. 2008
    ..To evaluate the local control rates and patterns of metastatic relapse in patients with localized myxoid liposarcoma treated with conservation surgery and radiotherapy (RT)...
  13. ncbi request reprint The effect of preoperative radiotherapy and reconstructive surgery on wound complications after resection of extremity soft-tissue sarcomas
    Jennifer F Tseng
    Sarcoma Center, University of Texas MD Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Ann Surg Oncol 13:1209-15. 2006
    ..Major wound complications (MWCs) are frequent after preoperative radiotherapy (RT) for extremity soft-tissue sarcoma (STS). We examined the rate of MWCs at a single institution with readily available reconstructive surgery...
  14. ncbi request reprint Periosteal margin in soft-tissue sarcoma
    Patrick P Lin
    Section of Orthopaedic Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77230, USA
    Cancer 109:598-602. 2007
    ..Soft-tissue sarcomas frequently rest in contact with bone. The purpose of the study was to evaluate the risk of local recurrence for sarcomas adjacent to bone and to determine whether the periosteum provides an adequate margin of resection...
  15. ncbi request reprint Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma
    Matthew T Ballo
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    J Clin Oncol 20:4555-8. 2002
    ..To evaluate the outcome and toxicity of a sphincter-sparing treatment strategy in the management of patients with anal-rectal melanoma...
  16. ncbi request reprint A critical assessment of adjuvant radiotherapy for inguinal lymph node metastases from melanoma
    Matthew T Ballo
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 11:1079-84. 2004
    ..Although patients with inguinal or pelvic lymph node (LN) metastases from melanoma may develop regional recurrence after dissection, the role of adjuvant radiotherapy remains controversial...
  17. ncbi request reprint Phase I trial of preoperative concurrent doxorubicin and radiation therapy, surgical resection, and intraoperative electron-beam radiation therapy for patients with localized retroperitoneal sarcoma
    Peter W T Pisters
    Department of Surgical Oncology, Unit 444, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 4009, USA
    J Clin Oncol 21:3092-7. 2003
    ....
  18. ncbi request reprint Sphincter-sparing local excision and hypofractionated radiation therapy for anorectal melanoma: a 20-year experience
    Patrick Kelly
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
    Cancer 117:4747-55. 2011
    ..In this study, the authors report their 20-year experience with sphincter-sparing excision combined with radiation therapy (RT) for the treatment of localized anorectal melanoma...
  19. ncbi request reprint Radiotherapy in the management of giant cell tumor of bone
    Jimmy J Caudell
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 57:158-65. 2003
    ..To evaluate the outcomes of patients with giant cell tumor of bone (GCTB) treated with radiotherapy (RT) with or without surgical resection...
  20. ncbi request reprint Long-term outcomes for synovial sarcoma treated with conservation surgery and radiotherapy
    B Ashleigh Guadagnolo
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 69:1173-80. 2007
    ..To evaluate prognostic factors and treatment outcomes in patients with localized synovial sarcoma treated with conservation surgery and radiotherapy (RT)...
  21. ncbi request reprint Management of locally recurrent soft-tissue sarcoma after prior surgery and radiation therapy
    Mylin A Torres
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:1124-9. 2007
    ....
  22. ncbi request reprint Adjuvant irradiation for cervical lymph node metastases from melanoma
    Matthew T Ballo
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas77030, USA
    Cancer 97:1789-96. 2003
    ..The risk of regional disease recurrence after surgery alone for lymph node metastases from melanoma is well documented. The role of adjuvant irradiation remains controversial...
  23. ncbi request reprint Long-term outcomes for desmoid tumors treated with radiation therapy
    B Ashleigh Guadagnolo
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:441-7. 2008
    ..To evaluate long-term outcomes in patients with desmoid fibromatosis treated with radiation therapy (RT), with or without surgery...
  24. ncbi request reprint Interval between surgery and radiotherapy: effect on local control of soft tissue sarcoma
    Matthew T Ballo
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 58:1461-7. 2004
    ..To evaluate the clinical significance of the interval between surgery and postoperative radiotherapy (RT) for patients with soft tissue sarcoma...
  25. doi request reprint Role of postoperative irradiation for patients with bilateral cervical nodal metastases from cutaneous melanoma: a critical assessment
    B Ashleigh Guadagnolo
    Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Head Neck 32:708-13. 2010
    ..The aim of this study was to evaluate the role of regional nodal radiation therapy (RT) for patients with bilateral cervical nodal metastases from melanoma...
  26. ncbi request reprint Prostate biopsy status and PSA nadir level as early surrogates for treatment failure: analysis of a prostate cancer randomized radiation dose escalation trial
    Alan Pollack
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 54:677-85. 2002
    ..These issues were investigated in a cohort of men with Stage T1-T3 prostate cancer who were randomized to receive between 70 Gy and 78 Gy and were prospectively biopsied at about 2 years after the completion of radiotherapy (RT)...
  27. ncbi request reprint Surgical management of soft tissue sarcomas of the hand and foot
    Patrick P Lin
    Section of Orthopaedic Oncology, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:852-61. 2002
    ..The purpose of the current study study was to determine oncologic outcome, particularly with respect to factors affecting local recurrence, distant recurrence, and disease-specific survival...
  28. ncbi request reprint Adult rhabdomyosarcoma: outcome following multimodality treatment
    Darren J Little
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:377-88. 2002
    ..Childhood rhabdomyosarcoma (RMS) has a relatively good prognosis. Outcome for adults with this disease is poorly documented due to its rarity...
  29. ncbi request reprint A population-based study of the quality of care in the diagnosis of large (≥5 cm) soft tissue sarcomas
    B Ashleigh Guadagnolo
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Oncol 35:455-61. 2012
    ....
  30. ncbi request reprint Impact of androgen deprivation therapy on survival in men treated with radiation for prostate cancer
    Alan Pollack
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Urology 60:22-30; discussion 30-1. 2002
    ..The results with long-term ADT are much more convincing than short-term ADT, and, as a consequence, 2 to 3 years are recommended...
  31. doi request reprint Mortality after cure of soft-tissue sarcoma treated with conservation surgery and radiotherapy
    B Ashleigh Guadagnolo
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:411-8. 2008
    ..The objective of the current study was to analyze the potential treatment-related mortality in long-term survivors of soft-tissue sarcoma (STS) treated with radiotherapy (RT) and conservation surgery...
  32. pmc Outcomes after definitive treatment for cutaneous angiosarcoma of the face and scalp
    B Ashleigh Guadagnolo
    Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Head Neck 33:661-7. 2011
    ..The aim of the present analysis was to retrospectively evaluate outcomes in patients with cutaneous angiosarcoma of the face/scalp treated curatively with surgery, radiation therapy (RT), or a combination of surgery and RT...
  33. ncbi request reprint Quality-of-life questionnaire results 2 and 3 years after radiotherapy for prostate cancer in a randomized dose-escalation study
    Darren J Little
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Urology 62:707-13. 2003
    ..To assess patient-reported prostate cancer-specific quality of life 2 and 3 years after radiotherapy to the prostate in a randomized dose-escalation trial of 70 versus 78 Gy conducted from 1993 to 1998...
  34. ncbi request reprint Radiation therapy for soft tissue sarcoma
    Matthew T Ballo
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Box 97, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Surg Oncol Clin N Am 12:449-67, vii. 2003
    ..This article focuses primarily on the role of radiation for malignant soft tissue sarcoma and selected borderline tumors...
  35. ncbi request reprint Significance of dose in postoperative radiotherapy for soft tissue sarcoma
    Gunar K Zagars
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:473-81. 2003
    ..For soft tissue sarcoma, adjuvant postoperative radiotherapy improves the local control rate over surgery alone. However, the issue of a dose-control relationship is controversial and was addressed in this study...
  36. ncbi request reprint Optimizing treatment of desmoid tumors
    Dina Lev
    Department of Cancer Biology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 25:1785-91. 2007
    ....
  37. doi request reprint Osteosarcoma of the jaw/craniofacial region: outcomes after multimodality treatment
    B Ashleigh Guadagnolo
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Cancer 115:3262-70. 2009
    ..The current study was performed to evaluate outcomes in patients with osteosarcoma of the head and neck (OHN) who were treated with surgery with or without radiotherapy (RT)...
  38. ncbi request reprint Extraosseous osteosarcoma: response to treatment and long-term outcome
    Syed A Ahmad
    Multidisciplinary Sarcoma Center and Department of Biostatistics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 20:521-7. 2002
    ..To evaluate the clinicopathologic features of extraosseous osteosarcoma (EOO), a rare soft tissue form of osteosarcoma, and to examine its response to multimodality therapy...
  39. doi request reprint Dermatofibrosarcoma protuberans: long-term outcomes of 53 patients treated with conservative surgery and radiation therapy
    Katherine O Castle
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 86:585-90. 2013
    ..To evaluate outcomes of conservative surgery and radiation therapy (RT) treatment in patients with dermatofibrosarcoma protuberans...
  40. doi request reprint Adjuvant radiation therapy for high-risk nodal metastases from cutaneous melanoma
    B Ashleigh Guadagnolo
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Lancet Oncol 10:409-16. 2009
    ..Overall survival remains poor for patients with macroscopic nodal metastases from malignant melanoma. Until advances in systemic treatment are available, regional nodal control is an important endpoint for patients with this disease...
  41. ncbi request reprint The follow-up of adult soft-tissue sarcomas
    Shreyaskumar R Patel
    Sarcoma Center, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Oncol 30:413-6. 2003
    ..The major goals of such an algorithm for soft-tissue sarcomas would be early identification of potentially curable recurrences, identification of therapy-related complications, and patient reassurance...
  42. ncbi request reprint Adjuvant irradiation for axillary metastases from malignant melanoma
    Matthew T Ballo
    Departments of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 52:964-72. 2002
    ..To evaluate the outcome and treatment-related toxicity for patients with axillary lymph node metastases from malignant melanoma treated with surgery and radiation, with or without systemic therapy...
  43. ncbi request reprint Molecular markers of outcome after radiotherapy in patients with prostate carcinoma: Ki-67, bcl-2, bax, and bcl-x
    Alan Pollack
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Cancer 97:1630-8. 2003
    ..The current study examined the association between expression levels of Ki-67, bcl-2, bax, and bcl-x in pretreatment biopsy specimens and patient outcome after definitive radiotherapy alone...
  44. pmc Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy
    Wei Lien Wang
    Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 085, Houston, TX, 77030, USA
    Clin Sarcoma Res 2:25. 2012
    ..We examined the histological changes, including adipocytic maturation, associated with this treatment in patients with myxoid liposarcoma and evaluated for prognostic significance...
  45. ncbi request reprint Prostate cancer radiation dose response: results of the M. D. Anderson phase III randomized trial
    Alan Pollack
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 53:1097-105. 2002
    ..A randomized radiotherapy dose escalation trial was undertaken between 1993 and 1998 to compare the efficacy of 70 vs. 78 Gy in controlling prostate cancer...
  46. ncbi request reprint Ki-67 staining is an independent correlate of biochemical failure in prostate cancer treated with radiotherapy
    Didier Cowen
    Department of Experimental Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Clin Cancer Res 8:1148-54. 2002
    ..To determine the significance of Ki-67/MIB1 staining as a marker of patient outcome for prostate cancer patients treated with radiotherapy...