Terri A Zachos
Affiliation: The Ohio State University
- Gene-mediated osteogenic differentiation of stem cells by bone morphogenetic proteins-2 or -6Terri A Zachos
Comparative Orthopedic Molecular Medicine and Applied Research Laboratories, Department of Veterinary Clinical Sciences, The Ohio State University, 601 Tharp Street, Columbus, Ohio 43210, USA
J Orthop Res 24:1279-91. 2006..BMP-2-transduced stem cells suspended in alginate culture may be a practical carrier system to support bone formation in vivo. BMP-6 induced a less robust cellular response than BMP-2, particularly in alginate culture...
- Evaluation of permissiveness and cytotoxic effects in equine chondrocytes, synovial cells, and stem cells in response to infection with adenovirus 5 vectors for gene deliveryAkikazu Ishihara
Comparative Orthopedic Molecular Medicine Laboratory, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, 43210, USA
Am J Vet Res 67:1145-55. 2006..To evaluate host cell permissiveness and cytotoxic effects of recombinant and modified adenoviral vectors in equine chondrocytes, synovial cells, and bone marrow-derived mesenchymal stem cells (BMD-MSCs)...
- Rodent models for the study of articular fracture healingTerri A Zachos
Comparative Orthopedic Molecular Medicine and Applied Research Laboratories, Ohio State University, Columbus, OH, USA
J Invest Surg 20:87-95. 2007..05). The nude rat model has the advantage of larger femora and the ability to implant xenograft cells. A lateral intercondylar osteotomy of the distal femur in the rat can be used to study the healing of articular fractures...
- Gene-Augmented Mesenchymal Stem Cells in Bone RepairTerri Zachos; Fiscal Year: 2006..We hypothesize that gene delivery of two different BMPs will result in accelerated healing of fractures, but by different mechanisms, confirmed by the production of unique cartilage- and bone-specific messages. ..