Z Yan

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc D(2) dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons
    Z Yan
    Laboratory of Molecular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 96:11607-12. 1999
  2. pmc Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
    Proc Natl Acad Sci U S A 97:6809-14. 2000
  3. ncbi request reprint Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 410:376-80. 2001
  4. pmc Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
    F Liu
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 98:11062-8. 2001
  5. ncbi request reprint Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
    Nature 402:669-71. 1999
  6. pmc Spinophilin regulates the formation and function of dendritic spines
    J Feng
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 97:9287-92. 2000
  7. ncbi request reprint Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity
    P B Allen
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06508, USA
    Neuroscience 140:897-911. 2006
  8. ncbi request reprint Chromatography on DEAE ion-exchange and Protein G affinity columns in tandem for the separation and purification of proteins
    Y Qi
    Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, PO Box 2871, Beijing 100085, China
    J Biochem Biophys Methods 49:263-73. 2001

Detail Information

Publications8

  1. pmc D(2) dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons
    Z Yan
    Laboratory of Molecular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 96:11607-12. 1999
    ..Our results suggest that MAPK and CREB signaling cascades are involved in the regulation of gene expression and other long-term effects of D(2) receptor activation...
  2. pmc Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
    Proc Natl Acad Sci U S A 97:6809-14. 2000
    ..HD mice also show defects in dopamine-regulated ion channels and in the D(1) dopamine/DARPP-32 signaling cascade. These presymptomatic defects may contribute to HD pathology...
  3. ncbi request reprint Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 410:376-80. 2001
    ..Our results suggest that changes in Cdk5 levels mediated by DeltaFosB, and resulting alterations in signalling involving D1 dopamine receptors, contribute to adaptive changes in the brain related to cocaine addiction...
  4. pmc Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
    F Liu
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 98:11062-8. 2001
    ..Together these results indicate that a CK1-Cdk5-DARPP-32 cascade may be involved in the regulation by mGluR agonists of Ca(2+) channels...
  5. ncbi request reprint Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    J A Bibb
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
    Nature 402:669-71. 1999
    ..Thus DARPP-32 is a bifunctional signal transduction molecule which, by distinct mechanisms, controls a serine/threonine kinase and a serine/threonine phosphatase...
  6. pmc Spinophilin regulates the formation and function of dendritic spines
    J Feng
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 97:9287-92. 2000
    ..In conclusion, spinophilin appears to be required for the regulation of the properties of dendritic spines...
  7. ncbi request reprint Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity
    P B Allen
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06508, USA
    Neuroscience 140:897-911. 2006
    ..These data establish a requirement for synaptic scaffolding in dopamine-mediated responses, and further indicate that spinophilin and neurabin play distinct roles in dopaminergic signal transduction and psychostimulant response...
  8. ncbi request reprint Chromatography on DEAE ion-exchange and Protein G affinity columns in tandem for the separation and purification of proteins
    Y Qi
    Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, PO Box 2871, Beijing 100085, China
    J Biochem Biophys Methods 49:263-73. 2001
    ....