Duen Hwa Yan

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi P202, an interferon-inducible protein, inhibits E2F1-mediated apoptosis in prostate cancer cells
    Duen Hwa Yan
    Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center and Graduate School of Biomedical Sciences, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Biochem Biophys Res Commun 303:219-22. 2003
  2. ncbi Prostate-specific antitumor activity by probasin promoter-directed p202 expression
    Yong Wen
    Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Carcinog 37:130-7. 2003
  3. ncbi Antitumor activity of IFIX, a novel interferon-inducible HIN-200 gene, in breast cancer
    Yi Ding
    1Department of Molecular and Cellular Oncology, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Oncogene 23:4556-66. 2004
  4. ncbi Proapoptotic and antitumor activities of adenovirus-mediated p202 gene transfer
    Yi Ding
    Departments of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 8:3290-7. 2002
  5. ncbi Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2
    Yi Ding
    Department of Molecular and Cellular Oncology, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Mol Cell Biol 26:1979-96. 2006
  6. ncbi A delayed chemically induced tumorigenesis in Brca2 mutant mice
    Duen Hwa Yan
    Department of Molecular and Cellular Oncology, The University of Texas, Houston, TX, USA
    Oncogene 23:1896-901. 2004
  7. ncbi Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin
    Hirohito Yamaguchi
    Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Carcinog 47:739-43. 2008
  8. ncbi Delivery of DNA to tumor cells using cationic liposomes
    Duen-Hwa Yan
    Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Center, Houston, TX, USA
    Methods Mol Biol 245:125-36. 2004

Collaborators

Detail Information

Publications8

  1. ncbi P202, an interferon-inducible protein, inhibits E2F1-mediated apoptosis in prostate cancer cells
    Duen Hwa Yan
    Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center and Graduate School of Biomedical Sciences, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Biochem Biophys Res Commun 303:219-22. 2003
    ..Therefore, our results suggest a possible link between the IFN and E2F pathways in regulating apoptosis...
  2. ncbi Prostate-specific antitumor activity by probasin promoter-directed p202 expression
    Yong Wen
    Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Carcinog 37:130-7. 2003
    ..Together, our results suggest that p202 suppresses prostate tumor growth, and that a prostate-specific antitumor effect can be achieved by systemic administration of liposome-mediated delivery of ARR2PB-p202...
  3. ncbi Antitumor activity of IFIX, a novel interferon-inducible HIN-200 gene, in breast cancer
    Yi Ding
    1Department of Molecular and Cellular Oncology, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Oncogene 23:4556-66. 2004
    ..Together, our results show that IFIXalpha1 possesses a tumor-suppressor activity and suggest IFIXalpha1 may be used as a therapeutic agent in cancer treatment...
  4. ncbi Proapoptotic and antitumor activities of adenovirus-mediated p202 gene transfer
    Yi Ding
    Departments of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 8:3290-7. 2002
    ..CONCLUSIONS: We conclude that Ad-p202 is a potent growth-inhibitory, proapoptotic, and tumor-suppressing agent. Ad-p202 may be further developed into an efficient therapeutic agent for human cancer gene therapy...
  5. ncbi Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2
    Yi Ding
    Department of Molecular and Cellular Oncology, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Mol Cell Biol 26:1979-96. 2006
    ..Finally, we show that IFIX mediates HDM2 downregulation in an IFN-inducible system. Together, these results suggest that IFIXalpha1 functions as a tumor suppressor by repressing HDM2 function...
  6. ncbi A delayed chemically induced tumorigenesis in Brca2 mutant mice
    Duen Hwa Yan
    Department of Molecular and Cellular Oncology, The University of Texas, Houston, TX, USA
    Oncogene 23:1896-901. 2004
    ..This suggestion may also provide a rational explanation for a previous unexpected finding that cigarette smoking appears to reduce the breast cancer risk of BRCA2 mutation carriers...
  7. ncbi Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin
    Hirohito Yamaguchi
    Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Carcinog 47:739-43. 2008
    ..Together, these data provide novel insights into the tumor-suppressive function of IFIXalpha...
  8. ncbi Delivery of DNA to tumor cells using cationic liposomes
    Duen-Hwa Yan
    Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Center, Houston, TX, USA
    Methods Mol Biol 245:125-36. 2004