Xiaofeng Xia

Summary

Affiliation: The Methodist Hospital
Country: USA

Publications

  1. pmc Genome-wide RNAi screening identifies genes inhibiting the migration of glioblastoma cells
    Jian Yang
    Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas, USA
    PLoS ONE 8:e61915. 2013
  2. doi request reprint Concise review: a high-content screening approach to stem cell research and drug discovery
    Xiaofeng Xia
    Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Houston, TX 77030, USA
    Stem Cells 30:1800-7. 2012
  3. pmc A quantitative analytic pipeline for evaluating neuronal activities by high-throughput synaptic vesicle imaging
    Jing Fan
    The Ting Tsung and Wei Fong Chao Center for Bioinformatics Research and Imaging for Neurosciences, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX 77030, USA
    Neuroimage 62:2040-54. 2012
  4. doi request reprint Differential diagnosis of lung carcinoma with three-dimensional quantitative molecular vibrational imaging
    Liang Gao
    Cornell University, The Methodist Hospital Research Institute, Weill Cornell Medical College, Department of Systems Medicine and Bioengineering, Houston, Texas 77030, USA
    J Biomed Opt 17:066017. 2012
  5. pmc Image-based chemical screening identifies drug efflux inhibitors in lung cancer cells
    Xiaofeng Xia
    Medical Systems Biology Laboratory, Center for Bioengineering and Informatics, The Methodist Hospital Research Institute, Houston, Texas 77030, USA
    Cancer Res 70:7723-33. 2010
  6. pmc A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
    Zheng Yin
    NCI Center for Modeling Cancer Development, The Methodist Hospital Research Institute, Weill Cornell Medical College, 6670 Bertner Avenue, R6 South, Houston, Texas 77030, USA
    Nat Cell Biol 15:860-71. 2013
  7. pmc DrugComboRanker: drug combination discovery based on target network analysis
    Lei Huang
    Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute Weill Cornell Medical College of Cornell University, Houston, TX 77030, USADepartment of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA
    Bioinformatics 30:i228-i236. 2014
  8. pmc Block-Cell-Printing for live single-cell printing
    Kai Zhang
    Department of Nanomedicine and Department of Systems Medicine and Bioengineering, Houston Methodist Research Institute, Houston, TX 77030
    Proc Natl Acad Sci U S A 111:2948-53. 2014

Collaborators

Detail Information

Publications8

  1. pmc Genome-wide RNAi screening identifies genes inhibiting the migration of glioblastoma cells
    Jian Yang
    Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas, USA
    PLoS ONE 8:e61915. 2013
    ..Interestingly, two genes, KHSRP and HCFC1, were also found to be correlated with the clinical outcome of GBM patients. These two genes have not been previously associated with cell migration...
  2. doi request reprint Concise review: a high-content screening approach to stem cell research and drug discovery
    Xiaofeng Xia
    Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Houston, TX 77030, USA
    Stem Cells 30:1800-7. 2012
    ..Here, we review the development of HCS technique and its past application on stem cells and discuss possible future developments...
  3. pmc A quantitative analytic pipeline for evaluating neuronal activities by high-throughput synaptic vesicle imaging
    Jing Fan
    The Ting Tsung and Wei Fong Chao Center for Bioinformatics Research and Imaging for Neurosciences, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX 77030, USA
    Neuroimage 62:2040-54. 2012
    ..The availability of such an automated system will open opportunities for investigation of synaptic neuropathology and identification of candidate therapeutics for neurodegeneration...
  4. doi request reprint Differential diagnosis of lung carcinoma with three-dimensional quantitative molecular vibrational imaging
    Liang Gao
    Cornell University, The Methodist Hospital Research Institute, Weill Cornell Medical College, Department of Systems Medicine and Bioengineering, Houston, Texas 77030, USA
    J Biomed Opt 17:066017. 2012
    ....
  5. pmc Image-based chemical screening identifies drug efflux inhibitors in lung cancer cells
    Xiaofeng Xia
    Medical Systems Biology Laboratory, Center for Bioengineering and Informatics, The Methodist Hospital Research Institute, Houston, Texas 77030, USA
    Cancer Res 70:7723-33. 2010
    ..The compounds identified by the screening may potentially be used as potential adjuvant to improve the efficacy of chemotherapeutic drugs...
  6. pmc A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
    Zheng Yin
    NCI Center for Modeling Cancer Development, The Methodist Hospital Research Institute, Weill Cornell Medical College, 6670 Bertner Avenue, R6 South, Houston, Texas 77030, USA
    Nat Cell Biol 15:860-71. 2013
    ..We show that these genes have a highly conserved function as regulators of cell shape in both mouse and human metastatic melanoma cells. ..
  7. pmc DrugComboRanker: drug combination discovery based on target network analysis
    Lei Huang
    Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute Weill Cornell Medical College of Cornell University, Houston, TX 77030, USADepartment of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA
    Bioinformatics 30:i228-i236. 2014
    ..These drug combinations could directly be used on patients with less concern of toxic effects. However, there is so far no effective computational approach to search effective drug combinations from the enormous number of possibilities...
  8. pmc Block-Cell-Printing for live single-cell printing
    Kai Zhang
    Department of Nanomedicine and Department of Systems Medicine and Bioengineering, Houston Methodist Research Institute, Houston, TX 77030
    Proc Natl Acad Sci U S A 111:2948-53. 2014
    ..Furthermore, primary neurons are also compatible with BloC-Printing...