WENDY A contact WOODWARD

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Radiation dose escalation for loco-regional recurrence of breast cancer after mastectomy
    Heath D Skinner
    Department of Radiation Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, TX 77030, USA
    Radiat Oncol 8:13. 2013
  2. pmc Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells
    Bisrat G Debeb
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Mol Cancer 9:180. 2010
  3. pmc Alpha6beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer
    Michael Z Gilcrease
    Department of Pathology, The University of Texas M, d, Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    J Exp Clin Cancer Res 28:67. 2009
  4. pmc Prospective analysis of carotid artery flow in breast cancer patients treated with supraclavicular irradiation 8 or more years previously: no increase in ipsilateral carotid stenosis after radiation noted
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 112:268-73. 2008
  5. doi request reprint The role of locoregional therapy in inflammatory breast cancer
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Semin Oncol 35:78-86. 2008
  6. doi request reprint Cancer stem cells: markers or biomarkers?
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 1202, Houston, TX 77030, USA
    Cancer Metastasis Rev 27:459-70. 2008
  7. pmc Radiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)
    Wendy Ann Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77005, USA
    Semin Radiat Oncol 19:87-95. 2009
  8. ncbi request reprint African-American race is associated with a poorer overall survival rate for breast cancer patients treated with mastectomy and doxorubicin-based chemotherapy
    Wendy A Woodward
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:2662-8. 2006
  9. ncbi request reprint Prognostic value of nodal ratios in node-positive breast cancer
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:2910-6. 2006
  10. ncbi request reprint Supraclavicular radiation for breast cancer does not increase the 10-year risk of stroke
    Wendy A Woodward
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:2556-62. 2006

Research Grants

  1. Human Breast Cancer Stem Cell Surrogates
    Massimo Cristofanilli; Fiscal Year: 2009
  2. Human Breast Cancer Stem Cell Surrogates
    WENDY A contact WOODWARD; Fiscal Year: 2010
  3. Human Breast Cancer Stem Cell Surrogates
    Massimo Cristofanilli; Fiscal Year: 2009

Collaborators

Detail Information

Publications39

  1. pmc Radiation dose escalation for loco-regional recurrence of breast cancer after mastectomy
    Heath D Skinner
    Department of Radiation Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, TX 77030, USA
    Radiat Oncol 8:13. 2013
    ..Radiation is a standard component of treatment for patients with locoregional recurrence (LRR) of breast cancer following mastectomy. The current study reports the results of a 10% radiation dose escalation in these patients...
  2. pmc Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells
    Bisrat G Debeb
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Mol Cancer 9:180. 2010
    ..Herein we fully characterize cancer stem cell-like features in 293T human embryonic kidney cells...
  3. pmc Alpha6beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer
    Michael Z Gilcrease
    Department of Pathology, The University of Texas M, d, Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    J Exp Clin Cancer Res 28:67. 2009
    ..EGFR is also overexpressed in the basal subtype of breast cancer, and crosstalk between alpha6beta4 integrin and EGFR appears to be important in tumor progression...
  4. pmc Prospective analysis of carotid artery flow in breast cancer patients treated with supraclavicular irradiation 8 or more years previously: no increase in ipsilateral carotid stenosis after radiation noted
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 112:268-73. 2008
    ..In the current study, the authors performed a prospective study to examine the long-term risk of carotid artery stenosis after supraclavicular irradiation for breast cancer...
  5. doi request reprint The role of locoregional therapy in inflammatory breast cancer
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Semin Oncol 35:78-86. 2008
    ..The use of different schedules of treatment and possible combination approaches are reviewed and discussed...
  6. doi request reprint Cancer stem cells: markers or biomarkers?
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 1202, Houston, TX 77030, USA
    Cancer Metastasis Rev 27:459-70. 2008
    ..Specific antibodies directed at these markers have facilitated the isolation of hematopoietic stem cells by flow cytometry...
  7. pmc Radiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)
    Wendy Ann Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77005, USA
    Semin Radiat Oncol 19:87-95. 2009
    ..Implications for and uncertainties regarding incorporation of these concepts into the practice of modern radiation oncology are discussed...
  8. ncbi request reprint African-American race is associated with a poorer overall survival rate for breast cancer patients treated with mastectomy and doxorubicin-based chemotherapy
    Wendy A Woodward
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:2662-8. 2006
    ..African-American (AA) race has been associated with a worse outcome in breast cancer. It is unclear whether this is due to biological factors, socioeconomic factors, or both...
  9. ncbi request reprint Prognostic value of nodal ratios in node-positive breast cancer
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:2910-6. 2006
    ..Here we examine the data supporting the use of nodal ratios in breast cancer prognosis and consider the potential advantages and disadvantages of including nodal ratios in breast cancer staging...
  10. ncbi request reprint Supraclavicular radiation for breast cancer does not increase the 10-year risk of stroke
    Wendy A Woodward
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:2556-62. 2006
    ....
  11. doi request reprint Overcoming radiation resistance in inflammatory breast cancer
    Wendy A Woodward
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 116:2840-5. 2010
    ....
  12. doi request reprint Among women who experience a recurrence after postmastectomy radiation therapy irradiation is not associated with more aggressive local recurrence or reduced survival
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res Treat 123:597-605. 2010
    ..These data do not support the hypothesis that irradiation promotes biologically aggressive local recurrences...
  13. doi request reprint Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials
    Wendy A Woodward
    The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 74:1580-91. 2009
    ....
  14. ncbi request reprint Potential targets for improving radiosensitivity of breast tumor-initiating cells
    Wei Xu
    Division of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Anticancer Agents Med Chem 10:152-6. 2010
    ..In this review we will discuss recent efforts to identify and target these cells to selectively radiosensitize them with novel agents, as well as the TIC radiosensitizing potential of current therapies already in clinical use...
  15. doi request reprint The number of positive nodes and the ratio of positive to excised nodes are significant predictors of survival in women with micrometastatic node-positive breast cancer
    Pauline T Truong
    Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, BC, Canada
    Eur J Cancer 44:1670-7. 2008
    ....
  16. pmc Locoregional treatment outcomes after multimodality management of inflammatory breast cancer
    Ian J Bristol
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 72:474-84. 2008
    ....
  17. doi request reprint Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy
    Grace L Smith
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 26:5119-25. 2008
    ..Cerebrovascular disease is common in head and neck cancer patients, but it is unknown whether radiotherapy increases the cerebrovascular disease risk in this population...
  18. doi request reprint Radiation use and long-term survival in breast cancer patients with T1, T2 primary tumors and one to three positive axillary lymph nodes
    Thomas A Buchholz
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:1022-7. 2008
    ..For patients with Stage II breast cancer with one to three positive lymph nodes, controversy exists about whether radiation as a component of treatment provides a survival benefit...
  19. doi request reprint Risk of hypothyroidism in older breast cancer patients treated with radiation
    Grace L Smith
    Department of Breast Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 112:1371-9. 2008
    ..The authors assessed risk of hypothyroidism in breast cancer patients who were receiving RT to a supraclavicular field, which typically includes a portion of thyroid...
  20. pmc Risk of subclinical micrometastatic disease in the supraclavicular nodal bed according to the anatomic distribution in patients with advanced breast cancer
    Valerie K Reed
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:435-40. 2008
    ....
  21. ncbi request reprint Placement of radiopaque clips for tumor localization in patients undergoing neoadjuvant chemotherapy and breast conservation therapy
    Julia L Oh
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 110:2420-7. 2007
    ..The objective of this study was to determine whether patients with breast cancer who received breast-conservation therapy after neoadjuvant chemotherapy had improved outcomes if radiopaque clips were placed to mark the primary tumor...
  22. ncbi request reprint Treatment optimization using computed tomography-delineated targets should be used for supraclavicular irradiation for breast cancer
    Raweewan Liengsawangwong
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 69:711-5. 2007
    ....
  23. ncbi request reprint Cardiovascular death and second non-breast cancer malignancy after postmastectomy radiation and doxorubicin-based chemotherapy
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:327-35. 2003
    ..To assess the incidence of long-term toxicity after postmastectomy radiation and doxorubicin-based adjuvant chemotherapy...
  24. ncbi request reprint Locoregional recurrence after doxorubicin-based chemotherapy and postmastectomy: Implications for breast cancer patients with early-stage disease and predictors for recurrence after postmastectomy radiation
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:336-44. 2003
    ....
  25. ncbi request reprint Clinical investigation: regional nodal failure patterns in breast cancer patients treated with mastectomy without radiotherapy
    Eric A Strom
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 63:1508-13. 2005
    ....
  26. ncbi request reprint Optimizing locoregional control and survival for women with breast cancer: a review of current developments in postmastectomy radiotherapy
    Pauline T Truong
    British Columbia Cancer Agency, Vancouver Island Center, University of British Columbia, Victoria, BC, Canada
    Expert Rev Anticancer Ther 6:205-16. 2006
    ..They also summarize key issues related to the integration of PMRT with other treatment modalities...
  27. ncbi request reprint Fifteen-year results of a randomized prospective trial of hyperfractionated chest wall irradiation versus once-daily chest wall irradiation after chemotherapy and mastectomy for patients with locally advanced noninflammatory breast cancer
    Thomas A Buchholz
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 65:1155-60. 2006
    ....
  28. ncbi request reprint Locoregional control of clinically diagnosed multifocal or multicentric breast cancer after neoadjuvant chemotherapy and locoregional therapy
    Julia L Oh
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcolmbe Blvd, Unit 1202, Houston, TX 77030, USA
    J Clin Oncol 24:4971-5. 2006
    ....
  29. ncbi request reprint Multileaf field-in-field forward-planned intensity-modulated dose compensation for whole-breast irradiation is associated with reduced contralateral breast dose: a phantom model comparison
    Yerko O Borghero
    Department of Radiation Oncology, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Radiother Oncol 82:324-8. 2007
    ..However, a direct comparison of the scattered dose to the contralateral breast resulting from wedged and FiF-IMRT plans remains to be documented...
  30. ncbi request reprint Changes in the 2003 American Joint Committee on Cancer staging for breast cancer dramatically affect stage-specific survival
    Wendy A Woodward
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 21:3244-8. 2003
    ..To evaluate how implementation of the 2003 American Joint Committee on Cancer (AJCC) staging system will affect stage-specific survival of breast cancer patients...
  31. ncbi request reprint Effect of postmastectomy radiotherapy in patients <35 years old with stage II-III breast cancer treated with doxorubicin-based neoadjuvant chemotherapy and mastectomy
    Amit K Garg
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 69:1478-83. 2007
    ..The objective of this study was to assess the benefits of PMRT in patients <35 years old treated with doxorubicin-based neoadjuvant chemotherapy for Stage II-III breast cancer...
  32. ncbi request reprint Primary angiosarcomas of the breast
    Taimur Sher
    Department of Internal Medicine, Mount Sinai Medical Center, Miami Beach, Florida, USA
    Cancer 110:173-8. 2007
    ..The purpose of the study was to describe the clinicopathologic characteristics and clinical outcomes of patients with primary breast angiosarcoma...
  33. ncbi request reprint A gene signature in breast cancer
    Wendy A Woodward
    N Engl J Med 356:1887-8; author reply 1887-8. 2007
  34. ncbi request reprint Postmastectomy radiation improves the outcome of patients with locally advanced breast cancer who achieve a pathologic complete response to neoadjuvant chemotherapy
    Sean E McGuire
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:1004-9. 2007
    ..The aim of this study was to investigate the role of postmastectomy radiation therapy in women with breast cancer who achieved a pathologic complete response (pCR) to neoadjuvant chemotherapy...
  35. ncbi request reprint The ratio of positive to excised nodes identifies high-risk subsets and reduces inter-institutional differences in locoregional recurrence risk estimates in breast cancer patients with 1-3 positive nodes: an analysis of prospective data from British Colum
    Pauline T Truong
    Department of Radiation Oncology, British Columbia Cancer Agency Vancouver Island Centre, British Columbia Cancer Agency, University of British Columbia, Victoria, BC, Canada
    Int J Radiat Oncol Biol Phys 68:59-65. 2007
    ....
  36. ncbi request reprint Locoregional treatment outcomes for breast cancer patients with ipsilateral supraclavicular metastases at diagnosis
    Eugene H Huang
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:490-6. 2007
    ..To evaluate the locoregional efficacy of multimodality treatment for breast cancer patients who present with ipsilateral supraclavicular (SCV) disease without systemic metastases...
  37. ncbi request reprint On mammary stem cells
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 3498, USA
    J Cell Sci 118:3585-94. 2005
    ....
  38. ncbi request reprint Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line
    Mercy S Chen
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, M638a Houston, TX 77030 3498, USA
    J Cell Sci 120:468-77. 2007
    ..The COMMA-Dbeta-geo cell line may provide a useful model to study the signaling pathways that control mammary progenitor cell regulation...
  39. pmc WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells
    Wendy A Woodward
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:618-23. 2007
    ..These data demonstrate that, compared with differentiated cells, progenitor cells have different cell survival properties that may facilitate the development of targeted antiprogenitor cell therapies...

Research Grants3

  1. Human Breast Cancer Stem Cell Surrogates
    Massimo Cristofanilli; Fiscal Year: 2009
    ..This approach could be used to select patients for individualized therapy using targeted sensitizing agents based on the proposed preclinical studies. ..
  2. Human Breast Cancer Stem Cell Surrogates
    WENDY A contact WOODWARD; Fiscal Year: 2010
    ..This approach could be used to select patients for individualized therapy using targeted sensitizing agents based on the proposed preclinical studies. ..
  3. Human Breast Cancer Stem Cell Surrogates
    Massimo Cristofanilli; Fiscal Year: 2009
    ..This approach could be used to select patients for individualized therapy using targeted sensitizing agents based on the proposed preclinical studies. ..