JACKIE WOOD

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Anti-enteric neuronal antibodies and the irritable bowel syndrome
    Jackie D Wood
    Department of Physiology and Cell Biology, The Ohio State University Medical Center, Columbus, Ohio, USA
    J Neurogastroenterol Motil 18:78-85. 2012
  2. doi request reprint Nonruminant Nutrition Symposium: Neurogastroenterology and food allergies
    J D Wood
    Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus 43210, USA
    J Anim Sci 90:1213-23. 2012
  3. ncbi request reprint Neuropathy in the brain-in-the-gut
    J D Wood
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Public Health, Columbus, USA
    Eur J Gastroenterol Hepatol 12:597-600. 2000
  4. doi request reprint Enteric nervous system: sensory physiology, diarrhea and constipation
    Jackie D Wood
    Department of Physiology and Cell Biology and Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA
    Curr Opin Gastroenterol 26:102-8. 2010
  5. ncbi request reprint Enteric nervous system: reflexes, pattern generators and motility
    Jackie D Wood
    Department of Physiology and Cell Biology and Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA
    Curr Opin Gastroenterol 24:149-58. 2008
  6. ncbi request reprint Function of opioids in the enteric nervous system
    J D Wood
    Department of Physiology and Cell Biology, Ohio State University, Columbus, OH 43210, USA
    Neurogastroenterol Motil 16:17-28. 2004
  7. ncbi request reprint The enteric purinergic P2Y1 receptor
    Jackie D Wood
    Department of Physiology and Cell Biology and Internal Medicine, College of Medicine, Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, Ohio 43210 1218, USA
    Curr Opin Pharmacol 6:564-70. 2006
  8. pmc Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies
    J D Wood
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine, 304 Hamilton Hall, 1645 Neil Ave, Columbus, Ohio 43210 1218, USA
    Gut 55:445-7. 2006
  9. ncbi request reprint Slow excitatory metabotropic signal transmission in the enteric nervous system
    J D Wood
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
    Neurogastroenterol Motil 16:71-80. 2004
  10. ncbi request reprint The first nobel prize for integrated systems physiology: Ivan Petrovich Pavlov, 1904
    Jackie D Wood
    College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA
    Physiology (Bethesda) 19:326-30. 2004

Research Grants

  1. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2001
  2. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2002
  3. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2003
  4. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2004
  5. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2004
  6. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2005
  7. PURINERGIC NEUROGENIC MUCOSAL SECRETION
    JACKIE WOOD; Fiscal Year: 2005
  8. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2007
  9. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2001
  10. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2000

Collaborators

Detail Information

Publications51

  1. pmc Anti-enteric neuronal antibodies and the irritable bowel syndrome
    Jackie D Wood
    Department of Physiology and Cell Biology, The Ohio State University Medical Center, Columbus, Ohio, USA
    J Neurogastroenterol Motil 18:78-85. 2012
    ..Our study was designed to test a hypothesis that symptoms in a subset of patients with a diagnosis of IBS are associated with an autoimmune degenerative neuropathy in the enteric nervous system...
  2. doi request reprint Nonruminant Nutrition Symposium: Neurogastroenterology and food allergies
    J D Wood
    Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus 43210, USA
    J Anim Sci 90:1213-23. 2012
    ..Investigative approaches to immuno-ENS interactions merge the disciplines of mucosal immunology and ENS neurophysiology into the realm of neurogastroenterology...
  3. ncbi request reprint Neuropathy in the brain-in-the-gut
    J D Wood
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Public Health, Columbus, USA
    Eur J Gastroenterol Hepatol 12:597-600. 2000
    ..Detection of anti-enteric neuronal antibodies in the serum of patients with early symptoms of a functional gastrointestinal motility disorder may prove to be a useful diagnostic test for inflammatory enteric neuropathy...
  4. doi request reprint Enteric nervous system: sensory physiology, diarrhea and constipation
    Jackie D Wood
    Department of Physiology and Cell Biology and Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA
    Curr Opin Gastroenterol 26:102-8. 2010
    ..Progress in understanding mechanosensory detection in these processes, disordered enteric nervous system integration in diarrhea and constipation and pharmacotherapy is summarized...
  5. ncbi request reprint Enteric nervous system: reflexes, pattern generators and motility
    Jackie D Wood
    Department of Physiology and Cell Biology and Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA
    Curr Opin Gastroenterol 24:149-58. 2008
    ..Advances in understanding of the enteric nervous system (ENS) support the brain-in-the-gut concept. Progress relative to sensory neurons, reflex circuits and central pattern generators is summarized...
  6. ncbi request reprint Function of opioids in the enteric nervous system
    J D Wood
    Department of Physiology and Cell Biology, Ohio State University, Columbus, OH 43210, USA
    Neurogastroenterol Motil 16:17-28. 2004
    ..We review here the integrated systems of physiology and cellular neurobiology that are basic to understanding the actions of opioid agonists and antagonists in the digestive tract...
  7. ncbi request reprint The enteric purinergic P2Y1 receptor
    Jackie D Wood
    Department of Physiology and Cell Biology and Internal Medicine, College of Medicine, Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, Ohio 43210 1218, USA
    Curr Opin Pharmacol 6:564-70. 2006
    ....
  8. pmc Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies
    J D Wood
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine, 304 Hamilton Hall, 1645 Neil Ave, Columbus, Ohio 43210 1218, USA
    Gut 55:445-7. 2006
  9. ncbi request reprint Slow excitatory metabotropic signal transmission in the enteric nervous system
    J D Wood
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
    Neurogastroenterol Motil 16:71-80. 2004
    ....
  10. ncbi request reprint The first nobel prize for integrated systems physiology: Ivan Petrovich Pavlov, 1904
    Jackie D Wood
    College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA
    Physiology (Bethesda) 19:326-30. 2004
  11. ncbi request reprint Neuropathophysiology of irritable bowel syndrome
    Jackie D Wood
    Departments of Physiology and Cell Biology and Internal Medicine, Ohio State University College of Medicine and Public Health, Columbus, Ohio, USA
    J Clin Gastroenterol 35:S11-22. 2002
    ..This review details current concepts of the underlying pathophysiology in terms of the physiology of intestinal secretion, motility, nervous control, sensing function, immuno-neural communication, and the brain-gut axis...
  12. ncbi request reprint Enteric neuroimmunophysiology and pathophysiology
    Jackie D Wood
    Department of Physiology and Cell Biology and Internal Medicine, College of Medicine and Public Health, The Ohio State University, Columbus, USA
    Gastroenterology 127:635-57. 2004
    ..Integrative circuits in the ENS receive and interpret the chemical signals from the mast cells. Signals from the mast cells are interpreted by the ENS as a labeled code for the presence of a threat in the intestinal lumen...
  13. doi request reprint Enteric nervous system neuropathy: repair and restoration
    Jackie D Wood
    Department of Physiology and Cell Biology, and Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA
    Curr Opin Gastroenterol 27:106-11. 2011
    ....
  14. ncbi request reprint Visceral pain: spinal afferents, enteric mast cells, enteric nervous system and stress
    Jackie D Wood
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine Columbus, Ohio 43210, USA
    Curr Pharm Des 17:1573-5. 2011
    ..Advances in this sphere are translating to improved insight into chronic functional abdominal and pelvic pain syndromes in general...
  15. pmc Fundamentals of neurogastroenterology
    J D Wood
    Departments of Physiology and Internal Medicine, The Ohio State University College of Medicine and Public Health, Columbus 43210, USA
    Gut 45:II6-II16. 1999
    ....
  16. ncbi request reprint Neurotransmission at the interface of sympathetic and enteric divisions of the autonomic nervous system
    J D Wood
    Department of Physiology, The Ohio State University College of Medicine and Public Health, Columbus 43210, USA
    Chin J Physiol 42:201-10. 1999
    ..This is postulated to underlie the secretory diarrhea and abdominal discomfort associated with stress...
  17. pmc Glucagon-like peptide-1 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro
    Sara Baldassano
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine, Columbus, Ohio, USA
    Am J Physiol Gastrointest Liver Physiol 302:G352-8. 2012
    ....
  18. ncbi request reprint Effects of bacteria on the enteric nervous system: implications for the irritable bowel syndrome
    Jackie D Wood
    Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Public Health, 1645 Neil Avenue, Columbus, OH 43210, USA
    J Clin Gastroenterol 41:S7-19. 2007
    ..The symptom of explosive watery diarrhea becomes self-explanatory in this scenario...
  19. ncbi request reprint Pre- and postsynaptic inhibition by nociceptin in guinea pig small intestinal myenteric plexus in vitro
    S Liu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, Ohio State University, Columbus, Ohio 43210
    Am J Physiol Gastrointest Liver Physiol 281:G237-46. 2001
    ..The results suggest that nociceptin acts both pre- and postsynaptically by activating an ORL(1) receptor that is distinct from typical naloxone-sensitive opioid receptors...
  20. pmc Slow excitatory synaptic transmission mediated by P2Y1 receptors in the guinea-pig enteric nervous system
    H Z Hu
    Department of Physiology and Cell Biology, The Ohio State University, Columbus, USA
    J Physiol 550:493-504. 2003
    ..The P2Y1 receptor on the neurones was identified as a metabotropic receptor linked to activation of phospholipase C, synthesis of inositol 1,4,5-trisphosphate and mobilization of Ca2+ from intracellular stores...
  21. ncbi request reprint Neurogastroenterology of tegaserod (HTF 919) in the submucosal division of the guinea-pig and human enteric nervous system
    X Fang
    Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, OH 43210 1218, USA
    Neurogastroenterol Motil 20:80-93. 2008
    ..The 5-HT(2B) receptor subtype was not involved in actions at nicotinic synapses or stimulation of secretion...
  22. ncbi request reprint P2X(7) receptors in the enteric nervous system of guinea-pig small intestine
    H Z Hu
    Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio 43210-1218, USA
    J Comp Neurol 440:299-310. 2001
    ..The mucosa, submucosal blood vessels, and the circular muscle coat also showed P2X(7) receptor immunoreactivity...
  23. pmc Differential actions of urocortins on neurons of the myenteric division of the enteric nervous system in guinea pig distal colon
    Sumei Liu
    Department of Physiology and Cell Biology, College of Medicine, Ohio State University, Columbus, OH, USA
    Br J Pharmacol 159:222-36. 2010
    ..Nevertheless, details of the neural mechanism of action for Ucns have been unclear. We have, here, tested the hypothesis that Ucns act in the enteric nervous system (ENS) to influence colonic motor behaviour...
  24. ncbi request reprint Immunoreactivity of Hu proteins facilitates identification of myenteric neurones in guinea-pig small intestine
    Z Lin
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA
    Neurogastroenterol Motil 14:197-204. 2002
    ..Anti-Hu immunostaining was judged to be an acceptable method for obtaining reliable estimates of total numbers of myenteric neurones in relation to other specific histochemical properties such as histamine binding...
  25. ncbi request reprint The P2Y purinergic receptor expressed by enteric neurones in guinea-pig intestine
    N Gao
    Department of Physiology and Cell Biology, The Ohio State University, Columbus, 43210, USA
    Neurogastroenterol Motil 18:316-23. 2006
    ..5. The results add to existing evidence for expression of a functional P2Y(1) purinergic receptor in neurones of the submucosal division of the ENS...
  26. ncbi request reprint Presynaptic inhibition produced by histamine at nicotinic synapses in enteric ganglia
    K Tamura
    Department of Physiology, College of Medicine, Ohio State University, Columbus 43210
    Neuroscience 25:171-9. 1988
    ..Burimamide, a histamine antagonist with higher activity at putative H3 receptors than H2 receptors, effectively reversed the inhibitory action of histamine on the excitatory postsynaptic potentials.(ABSTRACT TRUNCATED AT 250 WORDS)..
  27. ncbi request reprint Stimulation of formation of adenosine 3',5'-phosphate by histamine in myenteric ganglia isolated from guinea-pig small intestine
    Y Xia
    Department of Physiology, College of Medicine, Ohio State University, Columbus 43210, USA
    Eur J Pharmacol 316:81-5. 1996
    ..We conclude that histamine acts at the histamine H2 receptor subtype to stimulate adenylate cyclase and the formation of cAMP in myenteric ganglia of the guinea-pig small bowel...
  28. ncbi request reprint Galanin suppresses calcium conductance and activates inwardly rectifying potassium channels in myenteric neurones from guinea-pig small intestine
    J Ren
    Department of Physiology and Cell Biology, College of Medicine and Public Health, Ohio State University, OH 43210-1218, USA
    Neurogastroenterol Motil 13:247-54. 2001
    ..However, galantide alone suppressed ICa. The results suggest two mechanisms of action for galanin: one is opening of inwardly rectifying potassium channels and the second is blockade of voltage-activated calcium channels...
  29. ncbi request reprint Synaptic behavior of myenteric neurons in guinea pig distal colon
    P R Wade
    Department of Physiology, College of Medicine, Ohio State University, Columbus 43210
    Am J Physiol 255:G184-90. 1988
    ..Compared with synaptic behavior of small intestinal myenteric neurons, the notable differences were absence of the rundown phenomenon for fast EPSPs in the colonic neurons and a greater incidence of spontaneously occurring fast EPSPs...
  30. pmc Electrophysiological subtypes of inhibitory P1 purinoceptors on myenteric neurones of guinea-pig small bowel
    F L Christofi
    Department of Physiology, College of Medicine, Ohio State University, Columbus 43210
    Br J Pharmacol 113:703-10. 1994
    ..Adenosine also suppresses nicotinic cholinergic transmission by activating presynaptic high affinity Al receptors...
  31. ncbi request reprint Chemical coding and electrophysiology of enteric neurons expressing neurofilament 145 in guinea pig gastrointestinal tract
    Hong Zhen Hu
    Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, 1645 Neil Avenue, Columbus, OH 43210 1218, USA
    J Comp Neurol 442:189-203. 2002
    ..Absence of NF145 from ganglion cells in the submucosal plexus is an example of differences between myenteric and submucosal components of the enteric nervous system...
  32. ncbi request reprint Neuroimmune interactions in guinea pig stomach and small intestine
    Sumei Liu
    Department of Physiology and Cell Biology, Ohio State University, College of Medicine and Public Health, Columbus 43210, USA
    Am J Physiol Gastrointest Liver Physiol 284:G154-64. 2003
    ..Histamine, prostaglandins, and leukotrienes are paracrine signals in the communication pathway from mast cells to the small intestinal ENS...
  33. ncbi request reprint Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine
    Chuanyun Gao
    Department of Physiology and Cell Biology, The Ohio State University, College of Medicine and Public Health, Columbus, Ohio, USA
    Gastroenterology 123:1554-64. 2002
    ..This study identified the effects on myenteric neurons of activating PARs and investigated underlying mechanisms of action...
  34. ncbi request reprint Actions of cysteinyl leukotrienes in the enteric nervous system of guinea-pig stomach and small intestine
    Sumei Liu
    Department of Physiology and Cell Biology, The Ohio State University, College of Medicine and Public Health, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    Eur J Pharmacol 459:27-39. 2003
    ..The receptor mediating these effects was distinct from currently recognized cysteinyl leukotriene receptor subtypes (CysLT(1) and CysLT(2) receptors) and may represent a new receptor subtype...
  35. pmc Neuropathophysiology of functional gastrointestinal disorders
    Jackie D Wood
    World J Gastroenterol 13:1313-32. 2007
    ..This review details current concepts for the underlying pathophysiology in terms of the physiology of intestinal secretion, motility, nervous control, sensing function, immuno-neural communication and the brain-gut axis...
  36. pmc Actions of bradykinin on electrical and synaptic behavior of neurones in the myenteric plexus of guinea-pig small intestine
    Hong Zhen Hu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210 1218, U S A
    Br J Pharmacol 138:1221-32. 2003
    ..Once formed and released, the prostaglandins act to elevate the excitability of ganglion cells in the myenteric plexus and to suppress the synaptic release of neurotransmitters...
  37. ncbi request reprint Inhibitory neuromuscular transmission mediated by the P2Y1 purinergic receptor in guinea pig small intestine
    Guo Du Wang
    Dept of Physiology and Cell Biology, The Ohio State Univ, College of Medicine and Public Health, 304 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210, USA
    Am J Physiol Gastrointest Liver Physiol 292:G1483-9. 2007
    ..The results support ATP as a neurotransmitter for IJPs in the intestine and are consistent with the hypothesis that the P2Y(1) purinergic receptor subtype mediates the action of ATP...
  38. ncbi request reprint Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine
    Na Gao
    Dept of Physiology and Cell Biology, Columbus, OH 43210 1218, USA
    Am J Physiol Gastrointest Liver Physiol 292:G492-500. 2007
    ....
  39. ncbi request reprint Angiotensin receptors and actions in guinea pig enteric nervous system
    Guo Du Wang
    Dept of Physiology and Cell Biology, The Ohio State University, College of Medicine and Public Health, Columbus, OH 43210, USA
    Am J Physiol Gastrointest Liver Physiol 289:G614-26. 2005
    ..The enhanced presence of norepinephrine is expected to suppress fast and slow excitatory neurotransmission in the enteric microcircuits and to suppress neurogenic mucosal secretion...
  40. ncbi request reprint Actions of galanin on neurotransmission in the submucous plexus of guinea pig small intestine
    Sumei Liu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    Eur J Pharmacol 471:49-58. 2003
    ..The evidence suggests that the galanin GAL1 receptor, but not the galanin GAL2 receptor, mediated the presynaptic and postsynaptic inhibitory actions of galanin...
  41. ncbi request reprint Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine
    Xiucai Fang
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210 1218, USA
    Eur J Pharmacol 536:113-22. 2006
    ..Our evidence suggests that ATP is released as a neurotransmitter to stimulate neurogenic mucosal secretion by binding to P2Y1 receptors expressed by VIP-ergic secretomotor neurons...
  42. ncbi request reprint Fundamentals of neurogastroenterology: basic science
    David Grundy
    Department of Biomedical Sciences, University of Sheffield, Sheffield, England
    Gastroenterology 130:1391-411. 2006
    ..Continued focus on neurogastroenterologic factors that underlie the development of symptoms will lead to mechanistic understanding that is expected to directly benefit the large contingent of patients and care-givers who deal with FGIDs...
  43. ncbi request reprint Potentiation of TRPV3 channel function by unsaturated fatty acids
    Hong Zhen Hu
    Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio 43210, USA
    J Cell Physiol 208:201-12. 2006
    ..These results suggest a novel mechanism regulating the TRPV3 response to inflammation, which differs from TRPV1 and TRPV4, and involves a direct action of free fatty acids on the channel...
  44. pmc Beta-nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle
    Violeta N Mutafova-Yambolieva
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Proc Natl Acad Sci U S A 104:16359-64. 2007
    ..beta-NAD meets the traditional criteria for a neurotransmitter that contributes to enteric inhibitory regulation of visceral smooth muscles...
  45. ncbi request reprint Sodium conductance in cultured myenteric AH-type neurons from guinea-pig small intestine
    Alexander V Zholos
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus 43210 1218, USA
    Auton Neurosci 96:93-102. 2002
    ....
  46. ncbi request reprint Metabotropic signal transduction for bradykinin in submucosal neurons of guinea pig small intestine
    Hong Zhen Hu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210 1218, USA
    J Pharmacol Exp Ther 309:310-9. 2004
    ....
  47. pmc Distribution and chemical coding of corticotropin-releasing factor-immunoreactive neurons in the guinea pig enteric nervous system
    Sumei Liu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus, 43210 1218, USA
    J Comp Neurol 494:63-74. 2006
    ..CRF(1)-IR was expressed in neuronal neighbors of those with CRF-IR. Collective evidence suggests that VIPergic secretomotor neurons might provide synaptic input to neighboring cholinergic neurons...
  48. ncbi request reprint Action of bradykinin in the submucosal plexus of guinea pig small intestine
    Hong Zhen Hu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210 1218, USA
    J Pharmacol Exp Ther 309:320-7. 2004
    ..Pathophysiological significance of the excitatory actions on secretomotor neurons might be stimulated mucosal secretion and the secretory diarrhea associated with intestinal inflammatory states...
  49. ncbi request reprint Expression of type 1 corticotropin-releasing factor receptor in the guinea pig enteric nervous system
    Sumei Liu
    Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210 1218, USA
    J Comp Neurol 481:284-98. 2005
    ..Actions on enteric neurons might underlie the neural mechanisms by which stress-related release of CRF in the periphery alters intestinal propulsive motor function, mucosal secretion, and barrier functions...
  50. ncbi request reprint 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3
    Hong Zhen Hu
    Department of Physiology and Cell Biology, The Ohio State University, Columbus Ohio 43210, USA
    J Biol Chem 279:35741-8. 2004
    ..Our data suggest the existence of a common activation mechanism for TRPV1, TRPV2, and TRPV3 that may serve as a therapeutic target for pain management and treatment for diseases caused by hypersensitivity and temperature misregulation...

Research Grants29

  1. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2001
    ..The overall goal of the study is to understand better the neurophysiology underlying gastrointestinal immuno-neural communication and its involvement in the symptomatology of diarrhea, abdominal pain and intestinal inflammation. ..
  2. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2002
    ..The overall goal of the study is to better understand the role of bradykinin in motility disturbances, diarrhea, abdominal pain and inflammation. ..
  3. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2003
    ..The overall goal of the study is to better understand the role of bradykinin in motility disturbances, diarrhea, abdominal pain and inflammation. ..
  4. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2004
    ..The overall goal of the study is to better understand the role of bradykinin in motility disturbances, diarrhea, abdominal pain and inflammation. ..
  5. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2004
    ..Dephosphorylation of the channels by the phosphatase, calcineurin, terminates slow EPSP. ..
  6. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2005
    ..The overall goal of the study is to better understand the role of bradykinin in motility disturbances, diarrhea, abdominal pain and inflammation. ..
  7. PURINERGIC NEUROGENIC MUCOSAL SECRETION
    JACKIE WOOD; Fiscal Year: 2005
    ....
  8. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2007
    ..Dephosphorylation of the channels by the phosphatase, calcineurin, terminates slow EPSP. ..
  9. BRADYKININ IN ENTERIC NEUROIMMUNE COMMUNICATION
    JACKIE WOOD; Fiscal Year: 2001
    ..The overall goal of the study is to better understand the role of bradykinin in motility disturbances, diarrhea, abdominal pain and inflammation. ..
  10. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2000
    ..The overall goal of the study is to understand better the neurophysiology underlying gastrointestinal immuno-neural communication and its involvement in the symptomatology of diarrhea, abdominal pain and intestinal inflammation. ..
  11. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 1993
    ..These results are expected to improve understanding of neural determinants of motor function in the lower esophageal sphincter and in the proximal and distal stomach, as well as mechanisms of gastro-pyloro-duodenal motor coordination...
  12. PURINERGIC NEUROGENIC MUCOSAL SECRETION
    JACKIE WOOD; Fiscal Year: 2007
    ....
  13. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2006
    ..Dephosphorylation of the channels by the phosphatase, calcineurin, terminates slow EPSP. ..
  14. PURINERGIC NEUROGENIC MUCOSAL SECRETION
    JACKIE WOOD; Fiscal Year: 2006
    ....
  15. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2005
    ..Dephosphorylation of the channels by the phosphatase, calcineurin, terminates slow EPSP. ..
  16. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 1999
    ..The overall goal of the study is to understand better the neurophysiology underlying gastrointestinal immuno-neural communication and its involvement in the symptomatology of diarrhea, abdominal pain and intestinal inflammation. ..
  17. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 1992
    ..These results are expected to improve understanding of neural determinants of motor function in the lower esophageal sphincter and in the proximal and distal stomach, as well as mechanisms of gastro-pyloro-duodenal motor coordination...
  18. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 2003
    ..Dephosphorylation of the channels by the phosphatase, calcineurin, terminates slow EPSP. ..
  19. FUNCTION OF THE ENTERIC NERVOUS SYSTEM
    JACKIE WOOD; Fiscal Year: 1990
    ....