Henry K Wong

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma
    Henry K Wong
    Division of Dermatology, Department of Internal Medicine, The Ohio State University, Gahanna, OH 43230, USA
    Discov Med 16:71-8. 2013
  2. doi request reprint Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)
    Henry K Wong
    Division of Dermatology, The Ohio State University, Columbus, OH 43221, USA
    Br J Haematol 155:150-66. 2011
  3. doi request reprint Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome
    Heather M Gibson
    Division of Dermatology, The Ohio State University, Columbus, OH, USA
    J Invest Dermatol 133:249-57. 2013
  4. pmc Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells
    Suresh de Silva
    Center for Retrovirus Research, Department of Veterinary Biosciences, The OhioState University, Columbus, OH 43210, USA
    J Biol Chem 288:9284-92. 2013
  5. doi request reprint Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation
    Benjamin H Kaffenberger
    Dermatology, Ohio State University College of Medicine, Columbus, Ohio 43216, USA
    J Am Acad Dermatol 68:489-92. 2013

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma
    Henry K Wong
    Division of Dermatology, Department of Internal Medicine, The Ohio State University, Gahanna, OH 43230, USA
    Discov Med 16:71-8. 2013
    ..This is supported by the efficacy of evolving therapeutic strategies that modulate gene regulation, such as HDAC inhibitors and methylation inhibitors in the treatment of this group of cancers. ..
  2. doi request reprint Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)
    Henry K Wong
    Division of Dermatology, The Ohio State University, Columbus, OH 43221, USA
    Br J Haematol 155:150-66. 2011
    ..This review summarizes the clinical epidemiology, staging and natural history of MF and SS; discusses the immunopathogenesis of MF and the functional role of the malignant T-cells; and reviews the latest advances in MF and SS treatment...
  3. doi request reprint Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome
    Heather M Gibson
    Division of Dermatology, The Ohio State University, Columbus, OH, USA
    J Invest Dermatol 133:249-57. 2013
    ..We also demonstrate the requirement of the GATA3/CTLA-4 regulatory pathway in fresh neoplastic CD4+ T cells. Targeting of this pathway may be beneficial in SS and other CTLA-4-overexpressing T-cell neoplasms...
  4. pmc Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells
    Suresh de Silva
    Center for Retrovirus Research, Department of Veterinary Biosciences, The OhioState University, Columbus, OH 43210, USA
    J Biol Chem 288:9284-92. 2013
    ..SAMHD1 expression was induced in CD4(+) T cell lines by blocking DNA methyltransferase activity, suggesting that promoter methylation is one of the key epigenetic mechanisms by which SAMHD1 expression is regulated...
  5. doi request reprint Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation
    Benjamin H Kaffenberger
    Dermatology, Ohio State University College of Medicine, Columbus, Ohio 43216, USA
    J Am Acad Dermatol 68:489-92. 2013
    ..Of these, 5 of 6 developed a recurrence of their psoriasis within 2 years. Based on a limited number of patients, psoriasis is likely to remit after allogeneic HSCT, but it is likely to recur after autologous HSCT...