Thomas Wilson

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Juvenile hormone involvement in Drosophila melanogaster male reproduction as suggested by the Methoprene-tolerant(27) mutant phenotype
    Thomas G Wilson
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    Insect Biochem Mol Biol 33:1167-75. 2003
  2. ncbi request reprint The molecular site of action of juvenile hormone and juvenile hormone insecticides during metamorphosis: how these compounds kill insects
    Thomas G Wilson
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, 318 West 12th Avenue, Columbus, OH 43210, USA
    J Insect Physiol 50:111-21. 2004
  3. pmc Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex
    Thomas G Wilson
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    Genetics 172:253-64. 2006
  4. ncbi request reprint Wide mutational spectrum of a gene involved in hormone action and insecticide resistance in Drosophila melanogaster
    Thomas G Wilson
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    Mol Genet Genomics 276:294-303. 2006
  5. pmc Overexpression of Methoprene-tolerant, a Drosophila melanogaster gene that is critical for juvenile hormone action and insecticide resistance
    Joshua Barry
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, Columbus, OH 43210, USA
    Insect Biochem Mol Biol 38:346-53. 2008
  6. ncbi request reprint Interaction of bHLH-PAS proteins involved in juvenile hormone reception in Drosophila
    Jakub Godlewski
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, Columbus, OH 43210, USA
    Biochem Biophys Res Commun 342:1305-11. 2006
  7. pmc Drosophila melanogaster Methoprene-tolerant (Met) gene homologs from three mosquito species: Members of PAS transcriptional factor family
    Shaoli Wang
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    J Insect Physiol 53:246-53. 2007
  8. doi request reprint Evolutionary divergence of the paralogs Methoprene tolerant (Met) and germ cell expressed (gce) within the genus Drosophila
    Aaron Baumann
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, 318 W 12th Ave, Columbus, OH 43210, USA
    J Insect Physiol 56:1445-55. 2010
  9. ncbi request reprint Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary
    David S Richard
    Department of Biology, Susquehanna University, Selinsgrove, PA 17870, USA
    J Insect Physiol 51:455-64. 2005

Research Grants

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Juvenile hormone involvement in Drosophila melanogaster male reproduction as suggested by the Methoprene-tolerant(27) mutant phenotype
    Thomas G Wilson
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    Insect Biochem Mol Biol 33:1167-75. 2003
    ....
  2. ncbi request reprint The molecular site of action of juvenile hormone and juvenile hormone insecticides during metamorphosis: how these compounds kill insects
    Thomas G Wilson
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, 318 West 12th Avenue, Columbus, OH 43210, USA
    J Insect Physiol 50:111-21. 2004
    ..Therefore, JH is a necessary molecule at certain times in insect development but becomes toxic when present during metamorphosis...
  3. pmc Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex
    Thomas G Wilson
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    Genetics 172:253-64. 2006
    ..We propose that MET and BRC interact to control transcription of one or more downstream effector genes, which can be disrupted either by mutations in Met or BR-C or by application of JH/JH agonist, which alters MET interaction with BRC...
  4. ncbi request reprint Wide mutational spectrum of a gene involved in hormone action and insecticide resistance in Drosophila melanogaster
    Thomas G Wilson
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    Mol Genet Genomics 276:294-303. 2006
    ..The variety of amino acid changes in MET that resulted in resistance may portend a rapid rise in resistance in response to increased use of JH insecticides in field insect populations...
  5. pmc Overexpression of Methoprene-tolerant, a Drosophila melanogaster gene that is critical for juvenile hormone action and insecticide resistance
    Joshua Barry
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, Columbus, OH 43210, USA
    Insect Biochem Mol Biol 38:346-53. 2008
    ..Adults overexpressing Met+ did not show enhanced oogenesis, ruling out MET as a limiting factor for this hormone-driven physiology...
  6. ncbi request reprint Interaction of bHLH-PAS proteins involved in juvenile hormone reception in Drosophila
    Jakub Godlewski
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, Columbus, OH 43210, USA
    Biochem Biophys Res Commun 342:1305-11. 2006
    ..However, JH-dependent interaction occurred between GCE and MET having point mutations in bHLH or PAS-A. During development, changes in JH titer may alter partner binding by MET and result in different gene expression patterns...
  7. pmc Drosophila melanogaster Methoprene-tolerant (Met) gene homologs from three mosquito species: Members of PAS transcriptional factor family
    Shaoli Wang
    Department of Entomology, Ohio State University, Columbus, OH 43210, USA
    J Insect Physiol 53:246-53. 2007
    ..aegypti and An. gambiae. These results suggest that a gene duplication occurred during the evolution of higher Diptera, resulting in Met and gce...
  8. doi request reprint Evolutionary divergence of the paralogs Methoprene tolerant (Met) and germ cell expressed (gce) within the genus Drosophila
    Aaron Baumann
    Department of Entomology, 400 Aronoff Laboratory, Ohio State University, 318 W 12th Ave, Columbus, OH 43210, USA
    J Insect Physiol 56:1445-55. 2010
    ..Our results suggest that Drosophila Met and gce experienced divergent evolutionary pressures following the duplication of an ancestral gce-like gene found in less derived holometabolous insects...
  9. ncbi request reprint Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary
    David S Richard
    Department of Biology, Susquehanna University, Selinsgrove, PA 17870, USA
    J Insect Physiol 51:455-64. 2005
    ..The ovary transplant experiments corroborate the endocrine results and demonstrate that insulin/insulin-like signaling (IIS) is necessary for vitellogenesis even when sufficient levels of JH, ecdysteroids or other factors are present...

Research Grants4

  1. Juvenile Hormone Receptor in Flies and Mosquitoes
    Thomas Wilson; Fiscal Year: 2007
    ..In addition, a better understanding of Met as a bHLH-PAS gene will further our knowledge of this family of transcriptional regulators, including homologous genes found in humans. ..