R Douglas Wilson

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcome
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 39:430-8; discussion 430-8. 2004
  2. ncbi Does a myelomeningocele sac compared to no sac result in decreased postnatal leg function following maternal fetal surgery for spina bifida aperta?
    R Douglas Wilson
    Department of Surgery and Obstetrics and Gynecology, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 22:348-51. 2007
  3. ncbi Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatment
    R Douglas Wilson
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
    Am J Med Genet A 140:151-5. 2006
  4. doi In utero therapy for fetal thoracic abnormalities
    R Douglas Wilson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Prenat Diagn 28:619-25. 2008
  5. ncbi Management of fetal tumors
    R Douglas Wilson
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Pennsylvania, USA
    Best Pract Res Clin Obstet Gynaecol 22:159-73. 2008
  6. ncbi Congenital abdominal wall defects: an update
    R Douglas Wilson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 19:385-98. 2004
  7. ncbi Sacrococcygeal teratomas: prenatal surveillance, growth and pregnancy outcome
    R Douglas Wilson
    Fetal Heart Program, The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 25:15-20. 2009
  8. ncbi Congenital pulmonary lymphangiectasis sequence: a rare, heterogeneous, and lethal etiology for prenatal pleural effusion
    R Douglas Wilson
    The Center for Fetal Diagnosis and Treatment, Department of Surgery at The Children s Hospital of Philadelphia University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    Prenat Diagn 26:1058-61. 2006
  9. ncbi The ex utero intrapartum therapy procedure for high-risk fetal lung lesions
    Holly L Hedrick
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 40:1038-43; discussion 1044. 2005
  10. ncbi Acute cardiovascular effects of fetal surgery in the human
    Jack Rychik
    Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
    Circulation 110:1549-56. 2004

Detail Information

Publications73

  1. ncbi Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcome
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 39:430-8; discussion 430-8. 2004
    ..To understand the natural history and define indications for fetal intervention in sacrococcygeal teratoma (SCT), the authors reviewed all cases of fetal SCT presenting for evaluation...
  2. ncbi Does a myelomeningocele sac compared to no sac result in decreased postnatal leg function following maternal fetal surgery for spina bifida aperta?
    R Douglas Wilson
    Department of Surgery and Obstetrics and Gynecology, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 22:348-51. 2007
    ..A fetus with large sac S1 myelomeningocele (MMC) but bilateral talipes prompted the question, 'Does the presence or size of an MMC sac affect postnatal leg function?'..
  3. ncbi Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatment
    R Douglas Wilson
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
    Am J Med Genet A 140:151-5. 2006
    ..In the appropriate situation, this maternal fetal surgery approach for CCAM is life-saving for the affected fetus with acceptable maternal morbidity risks in the present and future pregnancies...
  4. doi In utero therapy for fetal thoracic abnormalities
    R Douglas Wilson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Prenat Diagn 28:619-25. 2008
    ..Maternal morbidity is increased with the development of MIRROR syndrome following the presence of long-standing fetal hydrops and possible surgical procedures...
  5. ncbi Management of fetal tumors
    R Douglas Wilson
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Pennsylvania, USA
    Best Pract Res Clin Obstet Gynaecol 22:159-73. 2008
    ..To review the diagnosis, management, and treatment options of tumors presenting during fetal development...
  6. ncbi Congenital abdominal wall defects: an update
    R Douglas Wilson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 19:385-98. 2004
    ..To review published peer-reviewed literature regarding abdominal wall defects including gastroschisis and omphalocele...
  7. ncbi Sacrococcygeal teratomas: prenatal surveillance, growth and pregnancy outcome
    R Douglas Wilson
    Fetal Heart Program, The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 25:15-20. 2009
    ..Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment...
  8. ncbi Congenital pulmonary lymphangiectasis sequence: a rare, heterogeneous, and lethal etiology for prenatal pleural effusion
    R Douglas Wilson
    The Center for Fetal Diagnosis and Treatment, Department of Surgery at The Children s Hospital of Philadelphia University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    Prenat Diagn 26:1058-61. 2006
    ..Autopsy-identified CPL...
  9. ncbi The ex utero intrapartum therapy procedure for high-risk fetal lung lesions
    Holly L Hedrick
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 40:1038-43; discussion 1044. 2005
    ..Indications for the ex utero intrapartum therapy (EXIT) procedure have expanded to include any fetal anomaly in which resuscitation of the neonate may be compromised...
  10. ncbi Acute cardiovascular effects of fetal surgery in the human
    Jack Rychik
    Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
    Circulation 110:1549-56. 2004
    ..The indications for fetal surgery continue to expand, yet little is known about the acute sequelae of fetal surgery on the human cardiovascular system...
  11. ncbi Reproductive outcomes after pregnancy complicated by maternal-fetal surgery
    R Douglas Wilson
    Pediatric Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 191:1430-6. 2004
    ..The reproductive outcomes for women after the pregnancy complicated by maternal-fetal surgery were evaluated to obtain evidence-based information for prenatal risk counseling...
  12. ncbi Liver position and lung-to-head ratio for prediction of extracorporeal membrane oxygenation and survival in isolated left congenital diaphragmatic hernia
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 197:422.e1-4. 2007
    ..The purpose of this study was to determine the ability of liver position and lung-to-head ratio to predict outcome in isolated left congenital diaphragmatic hernia...
  13. doi Outcomes after postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions
    ANTHONY Y TSAI
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 43:513-7. 2008
    ..On the other hand, malignant degeneration, pneumonia, and pneumothorax are known consequences of cystic lung lesions. This study aims to assess the safety of resection for asymptomatic lung lesions that were diagnosed before birth...
  14. pmc A randomized trial of prenatal versus postnatal repair of myelomeningocele
    N Scott Adzick
    Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    N Engl J Med 364:993-1004. 2011
    ..Prenatal repair of myelomeningocele, the most common form of spina bifida, may result in better neurologic function than repair deferred until after delivery. We compared outcomes of in utero repair with standard postnatal repair...
  15. ncbi Chorioamniotic membrane separation following open fetal surgery: pregnancy outcome
    R Douglas Wilson
    Department of Surgery, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA
    Fetal Diagn Ther 18:314-20. 2003
    ....
  16. ncbi Impact of continuous intraoperative monitoring on outcomes in open fetal surgery
    Sundeep G Keswani
    Center for Fetal Diagnosis and Treatment and Fetal Heart Program at the Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:316-20. 2005
    ..We have developed an intraoperative monitoring strategy to continuously assess fetal hemodynamics. We hypothesized that this approach would enhance intraoperative management and survival...
  17. ncbi Fetal myelomeningocele repair: short-term clinical outcomes
    Mark P Johnson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadephia, PA 19104, USA
    Am J Obstet Gynecol 189:482-7. 2003
    ..The study was undertaken to evaluate short-term clinical outcomes with antenatal myelomeningocele (MMC) repair...
  18. ncbi Severe pulmonary hypoplasia associated with giant cervical teratomas
    Kenneth W Liechty
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 41:230-3. 2006
    ..The use of the ex utero intrapartum treatment (EXIT) procedure has salvaged many fetuses with giant neck masses. Despite an adequate airway, a subset of these patients die from an inability to achieve adequate gas exchange...
  19. ncbi Thoracoamniotic shunts: fetal treatment of pleural effusions and congenital cystic adenomatoid malformations
    R Douglas Wilson
    Department of Surgery, Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 19:413-20. 2004
    ....
  20. ncbi Prenatal course and postnatal management of peripheral bronchial atresia: association with congenital cystic adenomatoid malformation of the lung
    William H Peranteau
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 24:190-6. 2008
    ....
  21. doi Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomes
    Andrea T Badillo
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 43:647-53. 2008
    ..The purpose of this study was to correlate prenatal identification of additional gastrointestinal sonographic abnormalities with postnatal clinical outcome...
  22. ncbi Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007)
    R Douglas Wilson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 203:209.e1-6. 2010
    ..The reproductive and gynecologic outcomes for women after the pregnancy complicated by open maternal-fetal surgery (OMFS) were evaluated...
  23. ncbi Prenatal diagnosis and management of mainstem bronchial atresia
    Sundeep G Keswani
    Center for Fetal Diagnosis and Treatment, The Chhildren s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:74-8. 2005
    ..Post-mortem findings in both cases confirmed the presence of an atretic mainstem bronchus with massive enlargement of the lung. Bronchial atresia involving the mainstem bronchus is associated with a poor prognosis...
  24. ncbi Postnatal chest wall deformities after fetal thoracoamniotic shunting for congenital cystic adenomatoid malformation
    Aziz M Merchant
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, and Department of Surgery and Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 22:435-9. 2007
    ..Large macrocystic congenital cystic adenomatoid malformations (CCAMs) can be treated with thoracoamniotic (TA) shunting to reduce CCAM volume. Two CCAM fetuses treated with TA shunt had postnatal radiographic rib deformities...
  25. ncbi Right congenital diaphragmatic hernia: Prenatal assessment and outcome
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 39:319-23; discussion 319-23. 2004
    ..To understand the natural history of right congenital diaphragmatic hernia (CDH), the authors retrospectively reviewed 27 cases of right CDH that presented for prenatal evaluation or postnatal treatment...
  26. doi Congenital high airway obstruction syndrome: MR/US findings, effect on management, and outcome
    Andrew Mong
    Department of Radiology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Radiol 38:1171-9. 2008
    ..Prompt airway intervention at delivery after accurate prenatal diagnosis may allow survival of this otherwise fatal condition...
  27. doi Fetal thoracic and bladder shunts
    Stephanie Mann
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Semin Fetal Neonatal Med 15:28-33. 2010
    ....
  28. ncbi Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery
    Enrico Danzer
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 25:47-53. 2009
    ..To evaluate lower extremity neuromotor function (LENF) and short-term ambulatory potential following fetal myelomeningocele (fMMC) closure...
  29. ncbi Fetal head biometry assessed by fetal magnetic resonance imaging following in utero myelomeningocele repair
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 22:1-6. 2007
    ..To examine the impact of fetal myelomeningocele (MMC) repair on fetal head biometry and cerebrospinal fluid (CSF) spaces assessed by magnetic resonance imaging (MR) studies...
  30. ncbi Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MRI
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, Department of Radiology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    AJR Am J Roentgenol 187:W350-6. 2006
    ..The purpose of this study was to determine whether prenatal MRI provides additional information about fetal sacrococcygeal teratoma compared with prenatal sonography...
  31. ncbi Effect of maternal betamethasone administration on prenatal congenital cystic adenomatoid malformation growth and fetal survival
    William H Peranteau
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 22:365-71. 2007
    ..To evaluate the effect of prenatal steroid treatment on the growth of congenital cystic adenomatoid malformations (CCAM) and survival in affected fetuses not amenable to other percutaneous ultrasound-guided prenatal interventions...
  32. doi OEIS sequence--a rare congenital anomaly with prenatal evaluation and postnatal outcome in six cases
    Eleonor Tiblad
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Prenat Diagn 28:141-7. 2008
    ..To describe the outcome of children prenatally diagnosed with omphalocele, exstrophy of the cloaca, imperforate anus and spinal defects (OEIS)...
  33. ncbi Antenatal diagnosis and management of congenital cystic adenomatoid malformation
    Stephanie Mann
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Wood Center 5113, Philadelphia, PA 19104, USA
    Semin Fetal Neonatal Med 12:477-81. 2007
    ..Careful delivery planning by utilizing a multidisciplinary approach will optimize neonatal outcomes...
  34. ncbi Management of fetal mediastinal teratoma
    Aziz M Merchant
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 40:228-31. 2005
    ..The authors present 2 cases of fetal mediastinal teratoma that illustrate successful strategies for either of these presentations...
  35. ncbi Prenatally diagnosed fetal lung lesions with associated conotruncal heart defects: is there a genetic association?
    Margaret R Hüsler
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, PA 19104 4399, USA
    Prenat Diagn 27:1123-8. 2007
    ..Congenital lung malformation can easily be diagnosed by prenatal ultrasound. Associated extrapulmonary malformations such as heart defects and chromosomal aberrations are rare...
  36. ncbi Pregnancy outcomes following bipolar umbilical cord cauterization for selective termination in complicated monochorionic multiple gestations
    John G Ilagan
    Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Fetal Diagn Ther 23:153-8. 2008
    ..To review pregnancy and childhood outcomes following selective termination by ultrasound guided bipolar umbilical cord cauterization (UCC) in complicated monochorionic multifetal pregnancies...
  37. ncbi History of fetal diagnosis and therapy: Children's Hospital of Philadelphia experience
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, and Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 18:65-82. 2003
    ..Outcomes have been improved through carefully planned and coordinated perinatal management. In some cases of life-threatening or severely debilitating defects, prenatal surgery has been offered...
  38. ncbi Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstruction
    Jean Marc Biard
    Center for Fetal Diagnosis and Treatment, at The Children s Hospital of Philadelphia, and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
    Obstet Gynecol 106:503-8. 2005
    ..Limited information is available about long-term outcomes in children treated prenatally for lower urinary tract obstruction. Our aim was to evaluate outcomes in children treated in utero with vesicoamniotic shunts...
  39. ncbi The twin-twin transfusion syndrome: spectrum of cardiovascular abnormality and development of a cardiovascular score to assess severity of disease
    Jack Rychik
    Fetal Heart Program, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Obstet Gynecol 197:392.e1-8. 2007
    ..Current means of grading twin-twin transfusion syndrome does not characterize cardiovascular aspects adequately. We sought to develop a score that describes the magnitude of cardiovascular severity in twin-twin transfusion syndrome...
  40. ncbi Survival in primary congenital pulmonary lymphangiectasia with hydrops fetalis
    Pablo Laje
    Department of General Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 24:225-9. 2008
    ..The different aspects of the management of congenital pulmonary lymphangiectasia are discussed in this report, together with a review of the literature...
  41. ncbi In utero limb salvage: fetoscopic release of amniotic bands for threatened limb amputation
    Sundeep G Keswani
    The Center for Fetal Diagnosis and Treatment, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    J Pediatr Surg 38:848-51. 2003
    ..There were no perioperative complications. In select patients with isolated extremity ABS, early fetoscopic release may prevent amputation and allow improved limb development...
  42. ncbi Preliminary investigations into a new method of functional assessment of the fetal heart using a novel application of 'real-time' cardiac magnetic resonance imaging
    Mark A Fogel
    Division of Cardiology, Department of Pediatrics, University of Pennsylvania School of Medicine, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:475-80. 2005
    ..Because of quantitative echocardiographic limitations of fetal ventricular volumes as well as poor windows, we sought to determine if real-time magnetic resonance imaging (MRI) could be used...
  43. ncbi Prenatal ultrasound guided percutaneous shunts for obstructive uropathy and thoracic disease
    R Douglas Wilson
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Semin Pediatr Surg 12:182-9. 2003
    ..Thoracoamniotic shunt and thoracocentesis pregnancy loss risks for pleural effusion (PE) and macrocystic adenomatoid malformation of the lung (CCAM) are 5% and 0.5% to 1.0%, respectively...
  44. doi Low-dose fetal CT for evaluation of severe congenital skeletal anomalies: preliminary experience
    Teresa Victoria
    Diagnostic Imaging, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19103, USA
    Pediatr Radiol 42:S142-9. 2012
    ..The following review is a preliminary summary of our experience at the Children's Hospital of Philadelphia (CHOP) using low-dose fetal CT in the evaluation of severe fetal osseous abnormalities...
  45. doi Utility of fetal muscle biopsy for diagnosis of nemaline myopathy
    Stefanie B Kasperski
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 24:400-4. 2008
    ..To report and discuss prenatal diagnosis of nemaline myopathy (NM) using fetal muscle biopsy...
  46. ncbi First-trimester screening for trisomies 21 and 18
    Ronald Wapner
    Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA 19102, USA
    N Engl J Med 349:1405-13. 2003
    ..First-trimester markers of aneuploidy have been developed, but their use in combination has not been adequately evaluated in clinical practice...
  47. ncbi Principles of human teratology: drug, chemical, and infectious exposure
    R Douglas Wilson
    Philadelphia, PA, USA
    J Obstet Gynaecol Can 29:911-26. 2007
    ..To provide a teratology update for prescription and non-prescription drugs and infections during pregnancy...
  48. ncbi Prenatal evaluation for fetal surgery
    R Douglas Wilson
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Curr Opin Obstet Gynecol 14:187-93. 2002
    ..Ongoing evaluation of the sensitivity, specificity, positive and negative predicted values of these evaluation tools is required so that appropriate selection of fetuses for the surgery can be made...
  49. ncbi Prenatally diagnosed giant omphaloceles: short- and long-term outcomes
    Jean Marc Biard
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Philadelphia 19104 4399, USA
    Prenat Diagn 24:434-9. 2004
    ..To review prenatal findings, short- and long-term outcomes of giant omphaloceles (GO) managed at a single institution (1996-2001)...
  50. ncbi Fetal health surveillance guideline: antenatal and intrapartum consensus
    R Douglas Wilson
    J Obstet Gynaecol Can 29:972; author reply 972. 2007
  51. ncbi The association between early membrane rupture, latency, clinical chorioamnionitis, neonatal infection, and adverse perinatal outcomes in twin pregnancies complicated by preterm prelabour rupture of membranes
    Peter von Dadelszen
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada
    Twin Res 6:257-62. 2003
    ..Increased risk for neonatal sepsis at earlier delivery GA is consistent with gestation-dependent fetal immunocompetence. Early PPROM and long latencies were associated with increased adverse perinatal outcomes...
  52. doi Fetal cardiocentesis: a review of indications, risks, applications and technique
    Albert P Sarno
    Maternal Fetal Medicine Section, Perinatal Center, St Luke s Hospital and Health Network, Bethlehem, PA 18015, USA
    Fetal Diagn Ther 23:237-44. 2008
    ..To review the indications, applications and technique of fetal cardiocentesis...
  53. ncbi Teratogenicity associated with pre-existing and gestational diabetes
    Victoria M Allen
    Halifax, NS, Canada
    J Obstet Gynaecol Can 29:927-44. 2007
    ....
  54. ncbi Gastroschisis: growth patterns and a proposed prenatal surveillance protocol
    Denise A Netta
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Fetal Diagn Ther 22:352-7. 2007
    ..The growth assessment could be available as a prospective tool to direct an antepartum fetal surveillance protocol...
  55. ncbi Alpha-fetoprotein values in amniotic fluid obtained during early amniocentesis (11-13 weeks)
    Nwachukwu I Nwebube
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of British Columbia, Vancouver, BC, Canada
    Fetal Diagn Ther 17:25-8. 2002
    ..To determine the normal values of alpha-fetoprotein (AFP) in amniotic fluid between the gestational ages of 11 and 13 weeks and compare these with previously published values...
  56. ncbi Prenatal diagnosis of partial trisomy 1q and monosomy X in a fetus with a congenital lung lesion and hydrops fetalis
    Tracy L Pressey
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada
    Am J Med Genet A 143:1104-7. 2007
    ..2;q25 or q31)]. The incidence of chromosomal abnormalities with CCAM lesions is estimated at 1.6%. This is the first reported case of prenatally diagnosed partial trisomy 1q and monosomy X presenting as a fetal lung lesion and hydrops...
  57. pmc A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome
    Timothy M Crombleholme
    Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic, and Fetal Surgery, Cincinnati Children s Hospital, MLC 2023, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Am J Obstet Gynecol 197:396.e1-9. 2007
    ..The objective of the study was to examine the effect of selective fetoscopic laser photocoagulation (SFLP) vs serial amnioreduction (AR) on perinatal mortality in severe twin-twin transfusion syndrome (TTTS)...
  58. ncbi Nuchal index: a gestational age independent ultrasound marker for the detection of Down syndrome
    Kenneth I Lim
    University of British Columbia, Canada
    Prenat Diagn 22:1233-7. 2002
    ..To determine if the ultrasound marker Nuchal Index (NIx) is gestational age independent, and to determine its specificity and sensitivity for Down syndrome (DS) identification...
  59. ncbi New molecular techniques for the prenatal detection of chromosomal aneuploidy
    Rebecca Sparkes
    Calgary AB, Canada
    J Obstet Gynaecol Can 30:617-21, 622-7. 2008
    ..To review the molecular genetic techniques currently available for rapid prenatal diagnosis of fetal aneuploidy, as well as those still under investigation...
  60. ncbi Amniocentesis and women with hepatitis B, hepatitis C, or human immunodeficiency virus
    Gregory Davies
    J Obstet Gynaecol Can 25:145-48, 149-52. 2003
    ..To review the risk of in utero infection through amniocentesis in women with hepatitis B, hepatitis C, or human immunodeficiency virus (HIV)...
  61. ncbi The use of folic acid for the prevention of neural tube defects and other congenital anomalies
    R Douglas Wilson
    J Obstet Gynaecol Can 25:959-73. 2003
    ..OPTION: Folic acid supplementation is problematic, since 50% of pregnancies are unplanned and the health status of women may not be optimal...
  62. ncbi Large umbilical cord hemangioma: sonographic features with surgical pathologic correlation
    Suzanne D Iyoob
    Ultrasound Department, Hospital of the University of Pennsylvania, Ground Dulles Building, Philadelphia, PA 19104 USA
    J Ultrasound Med 25:1495-8. 2006
  63. ncbi Pregnancy loss rates after midtrimester amniocentesis
    R Douglas Wilson
    Obstet Gynecol 109:451-2; author reply 452-3. 2007
  64. ncbi Prenatal screening for fetal aneuploidy
    Anne M Summers
    J Obstet Gynaecol Can 29:146-79. 2007
    ..To develop a Canadian consensus document with recommendations on maternal screening for fetal aneuploidy(e.g., Down syndrome and trisomy 18) in pregnancy...
  65. ncbi Mid-trimester amniocentesis fetal loss rate
    R Douglas Wilson
    J Obstet Gynaecol Can 29:586-95. 2007
    ..To determine the postprocedure loss rate for mid-trimester genetic amniocentesis...
  66. ncbi Obstetric ultrasound: is it time for informed consent?
    Michiel Van Den Hof
    J Obstet Gynaecol Can 27:569-71. 2005
  67. ncbi Fetal soft markers in obstetric ultrasound
    Michiel C Van Den Hof
    J Obstet Gynaecol Can 27:592-636. 2005
    ..To evaluate ultrasound "soft markers" used in fetal genetic screening...
  68. ncbi Cell-free fetal DNA in the maternal circulation and its future uses in obstetrics
    R Douglas Wilson
    J Obstet Gynaecol Can 27:54-62. 2005
    ..To provide an introduction to new technologies involving maternal plasma cell-free fetal DNA for non-invasive prenatal diagnosis and screening in obstetrics...
  69. ncbi Elevated first-trimester nuchal translucency increases the risk of congenital heart defects
    Ray O Bahado-Singh
    Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Ohio 45267 0526, USA
    Am J Obstet Gynecol 192:1357-61. 2005
    ..We sought to evaluate the association between first trimester nuchal translucency measurement and the risk for major congenital heart defect in chromosomally normal fetuses...
  70. ncbi Late first-trimester placental disruption and subsequent gestational hypertension/preeclampsia
    Richard K Silver
    Evanston Hospital of Northwestern University Medical School, Evanston, Illinois 60201, USA
    Obstet Gynecol 105:587-92. 2005
    ..To evaluate the potential relationship between placental disruption in weeks 13 and 14 and the subsequent development of gestational hypertension or preeclampsia...
  71. ncbi Sequential pathways of testing after first-trimester screening for trisomy 21
    Lawrence D Platt
    Department of Obstetrics and Gynecology, Cedars Sinai Medical Center and David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    Obstet Gynecol 104:661-6. 2004
    ....
  72. ncbi Pre-conceptional vitamin/folic acid supplementation 2007: the use of folic acid in combination with a multivitamin supplement for the prevention of neural tube defects and other congenital anomalies
    R Douglas Wilson
    Philadelphia PA, USA
    J Obstet Gynaecol Can 29:1003-26. 2007
    ..OPTION: Supplementation with folic acid and vitamins is problematic, since 50% of pregnancies are unplanned, and women's health status may not be optimal when they conceive...
  73. ncbi Pregnancy outcomes after assisted reproductive technology
    Victoria M Allen
    Halifax, NS, Canada
    J Obstet Gynaecol Can 28:220-50. 2006
    ....