Research Topics
| R Douglas WilsonSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
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Publications
Prenatal evaluation for fetal surgeryR Douglas Wilson
The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Curr Opin Obstet Gynecol 14:187-93. 2002..Ongoing evaluation of the sensitivity, specificity, positive and negative predicted values of these evaluation tools is required so that appropriate selection of fetuses for the surgery can be made...- Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcomeHolly L Hedrick
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA
J Pediatr Surg 39:430-8; discussion 430-8. 2004..Amnioreduction, cyst aspiration, and surgical debulking are potentially life-saving interventions... - The ex utero intrapartum therapy procedure for high-risk fetal lung lesionsHolly L Hedrick
The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
J Pediatr Surg 40:1038-43; discussion 1044. 2005..Indications for the ex utero intrapartum therapy (EXIT) procedure have expanded to include any fetal anomaly in which resuscitation of the neonate may be compromised... - Liver position and lung-to-head ratio for prediction of extracorporeal membrane oxygenation and survival in isolated left congenital diaphragmatic herniaHolly L Hedrick
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
Am J Obstet Gynecol 197:422.e1-4. 2007..The purpose of this study was to determine the ability of liver position and lung-to-head ratio to predict outcome in isolated left congenital diaphragmatic hernia... - Reproductive outcomes after pregnancy complicated by maternal-fetal surgeryR Douglas Wilson
Pediatric Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA
Am J Obstet Gynecol 191:1430-6. 2004..The uterine rupture rate is similar to the rupture rate after "classical" cesarean section (4%-9%)... 
Sacrococcygeal teratomas: prenatal surveillance, growth and pregnancy outcomeR Douglas Wilson
Fetal Heart Program, The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Fetal Diagn Ther 25:15-20. 2009..Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment...- Outcomes after postnatal resection of prenatally diagnosed asymptomatic cystic lung lesionsANTHONY Y TSAI
The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr Surg 43:513-7. 2008..On the other hand, malignant degeneration, pneumonia, and pneumothorax are known consequences of cystic lung lesions. This study aims to assess the safety of resection for asymptomatic lung lesions that were diagnosed before birth... - A randomized trial of prenatal versus postnatal repair of myelomeningoceleN Scott Adzick
Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
N Engl J Med 364:993-1004. 2011..Prenatal repair of myelomeningocele, the most common form of spina bifida, may result in better neurologic function than repair deferred until after delivery. We compared outcomes of in utero repair with standard postnatal repair... - Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomesAndrea T Badillo
The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr Surg 43:647-53. 2008..The purpose of this study was to correlate prenatal identification of additional gastrointestinal sonographic abnormalities with postnatal clinical outcome... - Impact of continuous intraoperative monitoring on outcomes in open fetal surgerySundeep G Keswani
Center for Fetal Diagnosis and Treatment and Fetal Heart Program at the Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Fetal Diagn Ther 20:316-20. 2005..CONCLUSION: Continuous intraoperative fetal monitoring provides real time assessment of fetal hemodynamics which results in changes in intraoperative management. The overall outcomes in these critically ill fetuses have been improved... - Thoracoamniotic shunts: fetal treatment of pleural effusions and congenital cystic adenomatoid malformationsR Douglas Wilson
Department of Surgery, Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
Fetal Diagn Ther 19:413-20. 2004.... - Prenatal course and postnatal management of peripheral bronchial atresia: association with congenital cystic adenomatoid malformation of the lungWilliam H Peranteau
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Fetal Diagn Ther 24:190-6. 2008.... - Severe pulmonary hypoplasia associated with giant cervical teratomasKenneth W Liechty
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Pediatr Surg 41:230-3. 2006..Despite obtaining airway control, a subset of these patients will die because of pulmonary hypoplasia. When counseling patients with large cervical masses it is important to discuss potential pulmonary hypoplasia in these patients... - Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007)R Douglas Wilson
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
Am J Obstet Gynecol 203:209.e1-6. 2010..The reproductive and gynecologic outcomes for women after the pregnancy complicated by open maternal-fetal surgery (OMFS) were evaluated... - Acute cardiovascular effects of fetal surgery in the humanJack Rychik
Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
Circulation 110:1549-56. 2004..The indications for fetal surgery continue to expand, yet little is known about the acute sequelae of fetal surgery on the human cardiovascular system... - Postnatal chest wall deformities after fetal thoracoamniotic shunting for congenital cystic adenomatoid malformationAziz M Merchant
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, and Department of Surgery and Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
Fetal Diagn Ther 22:435-9. 2007..Large macrocystic congenital cystic adenomatoid malformations (CCAMs) can be treated with thoracoamniotic (TA) shunting to reduce CCAM volume. Two CCAM fetuses treated with TA shunt had postnatal radiographic rib deformities... - Congenital high airway obstruction syndrome: MR/US findings, effect on management, and outcomeAndrew Mong
Department of Radiology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Radiol 38:1171-9. 2008..Prompt airway intervention at delivery after accurate prenatal diagnosis may allow survival of this otherwise fatal condition... - Right congenital diaphragmatic hernia: Prenatal assessment and outcomeHolly L Hedrick
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA
J Pediatr Surg 39:319-23; discussion 319-23. 2004.... - Prenatal diagnosis and management of mainstem bronchial atresiaSundeep G Keswani
Center for Fetal Diagnosis and Treatment, The Chhildren's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Fetal Diagn Ther 20:74-8. 2005..Post-mortem findings in both cases confirmed the presence of an atretic mainstem bronchus with massive enlargement of the lung. Bronchial atresia involving the mainstem bronchus is associated with a poor prognosis... - Fetal myelomeningocele repair: short-term clinical outcomesMark P Johnson
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadephia, PA 19104, USA
Am J Obstet Gynecol 189:482-7. 2003..The study was undertaken to evaluate short-term clinical outcomes with antenatal myelomeningocele (MMC) repair... - Antenatal diagnosis and management of congenital cystic adenomatoid malformationStephanie Mann
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Wood Center 5113, Philadelphia, PA 19104, USA
Semin Fetal Neonatal Med 12:477-81. 2007..Careful delivery planning by utilizing a multidisciplinary approach will optimize neonatal outcomes... - OEIS sequence--a rare congenital anomaly with prenatal evaluation and postnatal outcome in six casesEleonor Tiblad
Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Prenat Diagn 28:141-7. 2008..To describe the outcome of children prenatally diagnosed with omphalocele, exstrophy of the cloaca, imperforate anus and spinal defects (OEIS)... - Does a myelomeningocele sac compared to no sac result in decreased postnatal leg function following maternal fetal surgery for spina bifida aperta?R Douglas Wilson
Department of Surgery and Obstetrics and Gynecology, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
Fetal Diagn Ther 22:348-51. 2007..A fetus with large sac S1 myelomeningocele (MMC) but bilateral talipes prompted the question, 'Does the presence or size of an MMC sac affect postnatal leg function?'.. - Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MRIEnrico Danzer
The Center for Fetal Diagnosis and Treatment, Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA
AJR Am J Roentgenol 187:W350-6. 2006..The additional anatomic resolution provided by MRI resulted in more accurate prenatal counseling and improved preoperative planning for surgical resection... - Fetal thoracic and bladder shuntsStephanie Mann
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Semin Fetal Neonatal Med 15:28-33. 2010.... - Management of fetal mediastinal teratomaAziz M Merchant
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA
J Pediatr Surg 40:228-31. 2005..CONCLUSIONS: Massive fetal mediastinal teratoma can result in fetal or neonatal mortality by a variety of mechanisms. Optimal prenatal and perinatal management is required to salvage fetuses compromised by this lesion... - Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgeryEnrico Danzer
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Fetal Diagn Ther 25:47-53. 2009..To evaluate lower extremity neuromotor function (LENF) and short-term ambulatory potential following fetal myelomeningocele (fMMC) closure... - Fetal head biometry assessed by fetal magnetic resonance imaging following in utero myelomeningocele repairEnrico Danzer
The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Fetal Diagn Ther 22:1-6. 2007..To examine the impact of fetal myelomeningocele (MMC) repair on fetal head biometry and cerebrospinal fluid (CSF) spaces assessed by magnetic resonance imaging (MR) studies... - Effect of maternal betamethasone administration on prenatal congenital cystic adenomatoid malformation growth and fetal survivalWilliam H Peranteau
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Fetal Diagn Ther 22:365-71. 2007..To evaluate the effect of prenatal steroid treatment on the growth of congenital cystic adenomatoid malformations (CCAM) and survival in affected fetuses not amenable to other percutaneous ultrasound-guided prenatal interventions... - Chorioamniotic membrane separation following open fetal surgery: pregnancy outcomeR Douglas Wilson
Department of Surgery, Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA
Fetal Diagn Ther 18:314-20. 2003..3) Delivery prior to 33 weeks gestation for MMC groups was 12/43 (28%) with 3 NND (7%). (4) Elective delivery at 36-37 weeks gestation was possible for 43% of the fetal surgery population... - Prenatally diagnosed fetal lung lesions with associated conotruncal heart defects: is there a genetic association?Margaret R Hüsler
The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, PA 19104 4399, USA
Prenat Diagn 27:1123-8. 2007..Congenital lung malformation can easily be diagnosed by prenatal ultrasound. Associated extrapulmonary malformations such as heart defects and chromosomal aberrations are rare... - Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstructionJean-Marc Biard
Center for Fetal Diagnosis and Treatment, at The Children's Hospital of Philadelphia, and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4399, USA
Obstet Gynecol 106:503-8. 2005..Although one third of the surviving babies required dialysis and transplantation, the majority have acceptable renal and bladder function and report satisfactory quality of life. LEVEL OF EVIDENCE: III... - Pregnancy outcomes following bipolar umbilical cord cauterization for selective termination in complicated monochorionic multiple gestationsJohn G Ilagan
Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Fetal Diagn Ther 23:153-8. 2008..To review pregnancy and childhood outcomes following selective termination by ultrasound guided bipolar umbilical cord cauterization (UCC) in complicated monochorionic multifetal pregnancies... - Congenital pulmonary lymphangiectasis sequence: a rare, heterogeneous, and lethal etiology for prenatal pleural effusionR Douglas Wilson
The Center for Fetal Diagnosis and Treatment, Department of Surgery at The Children s Hospital of Philadelphia University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
Prenat Diagn 26:1058-61. 2006..Autopsy-identified CPL... - Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatmentR Douglas Wilson
Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
Am J Med Genet A 140:151-5. 2006..In the appropriate situation, this maternal fetal surgery approach for CCAM is life-saving for the affected fetus with acceptable maternal morbidity risks in the present and future pregnancies... - Preliminary investigations into a new method of functional assessment of the fetal heart using a novel application of 'real-time' cardiac magnetic resonance imagingMark A Fogel
Division of Cardiology, Department of Pediatrics, University of Pennsylvania School of Medicine, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Fetal Diagn Ther 20:475-80. 2005..Because of quantitative echocardiographic limitations of fetal ventricular volumes as well as poor windows, we sought to determine if real-time magnetic resonance imaging (MRI) could be used... - Survival in primary congenital pulmonary lymphangiectasia with hydrops fetalisPablo Laje
Department of General Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Fetal Diagn Ther 24:225-9. 2008..The different aspects of the management of congenital pulmonary lymphangiectasia are discussed in this report, together with a review of the literature... - The twin-twin transfusion syndrome: spectrum of cardiovascular abnormality and development of a cardiovascular score to assess severity of diseaseJack Rychik
Fetal Heart Program, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Am J Obstet Gynecol 197:392.e1-8. 2007..Current means of grading twin-twin transfusion syndrome does not characterize cardiovascular aspects adequately. We sought to develop a score that describes the magnitude of cardiovascular severity in twin-twin transfusion syndrome... - In utero limb salvage: fetoscopic release of amniotic bands for threatened limb amputationSundeep G Keswani
The Center for Fetal Diagnosis and Treatment, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
J Pediatr Surg 38:848-51. 2003..There were no perioperative complications. In select patients with isolated extremity ABS, early fetoscopic release may prevent amputation and allow improved limb development... - Low-dose fetal CT for evaluation of severe congenital skeletal anomalies: preliminary experienceTeresa Victoria
Diagnostic Imaging, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19103, USA
Pediatr Radiol 42:S142-9. 2012..The following review is a preliminary summary of our experience at the Children's Hospital of Philadelphia (CHOP) using low-dose fetal CT in the evaluation of severe fetal osseous abnormalities... - Utility of fetal muscle biopsy for diagnosis of nemaline myopathyStefanie B Kasperski
The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
Fetal Diagn Ther 24:400-4. 2008..To report and discuss prenatal diagnosis of nemaline myopathy (NM) using fetal muscle biopsy... - Prenatal ultrasound guided percutaneous shunts for obstructive uropathy and thoracic diseaseR Douglas Wilson
The Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Semin Pediatr Surg 12:182-9. 2003..Thoracoamniotic shunt and thoracocentesis pregnancy loss risks for pleural effusion (PE) and macrocystic adenomatoid malformation of the lung (CCAM) are 5% and 0.5% to 1.0%, respectively... - Management of fetal tumorsR Douglas Wilson
The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Pennsylvania, USA
Best Pract Res Clin Obstet Gynaecol 22:159-73. 2008..To review the diagnosis, management, and treatment options of tumors presenting during fetal development... - First-trimester screening for trisomies 21 and 18Ronald Wapner
Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA 19102, USA
N Engl J Med 349:1405-13. 2003.... - In utero therapy for fetal thoracic abnormalitiesR Douglas Wilson
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Prenat Diagn 28:619-25. 2008..Maternal morbidity is increased with the development of MIRROR syndrome following the presence of long-standing fetal hydrops and possible surgical procedures... - Principles of human teratology: drug, chemical, and infectious exposureR Douglas Wilson
Philadelphia, PA, USA
J Obstet Gynaecol Can 29:911-26. 2007..To provide a teratology update for prescription and non-prescription drugs and infections during pregnancy... - History of fetal diagnosis and therapy: Children's Hospital of Philadelphia experienceHolly L Hedrick
Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, and Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Fetal Diagn Ther 18:65-82. 2003..Outcomes have been improved through carefully planned and coordinated perinatal management. In some cases of life-threatening or severely debilitating defects, prenatal surgery has been offered... - Congenital abdominal wall defects: an updateR Douglas Wilson
Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
Fetal Diagn Ther 19:385-98. 2004..To review published peer-reviewed literature regarding abdominal wall defects including gastroschisis and omphalocele... - Prenatal evaluation of the fetus with limb deficiency/hypoplasia - A case report and review of common congenital limb anomaliesStefanie B Kasperski
The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, PA, USA
J Pediatr Rehabil Med 2:189-93. 2009..A case report detailing the prenatal evaluation of a fetus with a skeletal dysplasia illustrates the importance of a comprehensive, multidisciplinary and dysmorphology-based approach... - Teratogenicity associated with pre-existing and gestational diabetesVictoria M Allen
Halifax, NS, Canada
J Obstet Gynaecol Can 29:927-44. 2007.... - Fetal cardiocentesis: a review of indications, risks, applications and techniqueAlbert P Sarno
Maternal Fetal Medicine Section, Perinatal Center, St Luke s Hospital and Health Network, Bethlehem, PA 18015, USA
Fetal Diagn Ther 23:237-44. 2008..To review the indications, applications and technique of fetal cardiocentesis... - Fetal health surveillance guideline: antenatal and intrapartum consensusR Douglas Wilson
J Obstet Gynaecol Can 29:972; author reply 972. 2007 
A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndromeTimothy M Crombleholme
Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic, and Fetal Surgery, Cincinnati Children s Hospital, MLC 2023, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Am J Obstet Gynecol 197:396.e1-9. 2007..The objective of the study was to examine the effect of selective fetoscopic laser photocoagulation (SFLP) vs serial amnioreduction (AR) on perinatal mortality in severe twin-twin transfusion syndrome (TTTS)...- Gastroschisis: growth patterns and a proposed prenatal surveillance protocolDenise A Netta
Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Fetal Diagn Ther 22:352-7. 2007..The growth assessment could be available as a prospective tool to direct an antepartum fetal surveillance protocol... - Prenatal diagnosis of partial trisomy 1q and monosomy X in a fetus with a congenital lung lesion and hydrops fetalisTracy L Pressey
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada
Am J Med Genet A 143:1104-7. 2007..2;q25 or q31)]. The incidence of chromosomal abnormalities with CCAM lesions is estimated at 1.6%. This is the first reported case of prenatally diagnosed partial trisomy 1q and monosomy X presenting as a fetal lung lesion and hydrops... - The association between early membrane rupture, latency, clinical chorioamnionitis, neonatal infection, and adverse perinatal outcomes in twin pregnancies complicated by preterm prelabour rupture of membranesPeter von Dadelszen
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada
Twin Res 6:257-62. 2003..Increased risk for neonatal sepsis at earlier delivery GA is consistent with gestation-dependent fetal immunocompetence. Early PPROM and long latencies were associated with increased adverse perinatal outcomes... - Prenatally diagnosed giant omphaloceles: short- and long-term outcomesJean-Marc Biard
The Center for Fetal Diagnosis and Treatment at The Children's Hospital of Philadelphia, Philadelphia 19104-4399, USA
Prenat Diagn 24:434-9. 2004..Parents need to be counseled prenatally about the probability of multiple surgeries and long hospitalization following birth... - Alpha-fetoprotein values in amniotic fluid obtained during early amniocentesis (11-13 weeks)Nwachukwu I Nwebube
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of British Columbia, Vancouver, BC, Canada
Fetal Diagn Ther 17:25-8. 2002..To determine the normal values of alpha-fetoprotein (AFP) in amniotic fluid between the gestational ages of 11 and 13 weeks and compare these with previously published values... - Late first-trimester placental disruption and subsequent gestational hypertension/preeclampsiaRichard K Silver
Evanston Hospital of Northwestern University Medical School, Evanston, Illinois 60201, USA
Obstet Gynecol 105:587-92. 2005..To evaluate the potential relationship between placental disruption in weeks 13 and 14 and the subsequent development of gestational hypertension or preeclampsia... - Sequential pathways of testing after first-trimester screening for trisomy 21Lawrence D Platt
Department of Obstetrics and Gynecology, Cedars Sinai Medical Center and David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Obstet Gynecol 104:661-6. 2004.... - The use of folic acid for the prevention of neural tube defects and other congenital anomaliesR Douglas Wilson
J Obstet Gynaecol Can 25:959-73. 2003..I-A) VALIDATION: This is a revision of a previous guideline and information from other consensus reviews from medical and government publications has been used... - Amniocentesis and women with hepatitis B, hepatitis C, or human immunodeficiency virusGregory Davies
J Obstet Gynaecol Can 25:145-48, 149-52. 2003..II-1B) VALIDATION: These guidelines have been approved by the SOGC Genetics Committee, SOGC Executive, and SOGC Council. SPONSORS: The Society of Obstetricians and Gynaecologists of Canada... - Nuchal index: a gestational age independent ultrasound marker for the detection of Down syndromeKenneth I Lim
University of British Columbia, Canada
Prenat Diagn 22:1233-7. 2002..To determine if the ultrasound marker Nuchal Index (NIx) is gestational age independent, and to determine its specificity and sensitivity for Down syndrome (DS) identification... - Elevated first-trimester nuchal translucency increases the risk of congenital heart defectsRay O Bahado-Singh
Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Ohio 45267 0526, USA
Am J Obstet Gynecol 192:1357-61. 2005..We sought to evaluate the association between first trimester nuchal translucency measurement and the risk for major congenital heart defect in chromosomally normal fetuses... - Large umbilical cord hemangioma: sonographic features with surgical pathologic correlationSuzanne D Iyoob
Ultrasound Department, Hospital of the University of Pennsylvania, Ground Dulles Building, Philadelphia, PA 19104 USA
J Ultrasound Med 25:1495-8. 2006 - Cell-free fetal DNA in the maternal circulation and its future uses in obstetricsR Douglas Wilson
J Obstet Gynaecol Can 27:54-62. 2005.... - New molecular techniques for the prenatal detection of chromosomal aneuploidyRebecca Sparkes
Calgary AB, Canada
J Obstet Gynaecol Can 30:617-21, 622-7. 2008..To review the molecular genetic techniques currently available for rapid prenatal diagnosis of fetal aneuploidy, as well as those still under investigation... - Obstetric ultrasound: is it time for informed consent?Michiel Van Den Hof
J Obstet Gynaecol Can 27:569-71. 2005 - Pregnancy outcomes after assisted reproductive technologyVictoria M Allen
Halifax, NS, Canada
J Obstet Gynaecol Can 28:220-50. 2006..Further ethical discussion and clinical research is required to evaluate appropriate indications for preimplantation genetic diagnosis. (III-B)... - Pregnancy loss rates after midtrimester amniocentesisR Douglas Wilson
Obstet Gynecol 109:451-2; author reply 452-3. 2007 - Prenatal screening for fetal aneuploidyAnne M Summers
J Obstet Gynaecol Can 29:146-79. 2007.... - Mid-trimester amniocentesis fetal loss rateR Douglas Wilson
J Obstet Gynaecol Can 29:586-95. 2007..SUMMARY STATEMENT: The risk of postprocedure loss is unique to the individual and is based on multiple variables... - Fetal soft markers in obstetric ultrasoundMichiel C Van Den Hof
J Obstet Gynaecol Can 27:592-636. 2005..VALIDATION: Peer-reviewed guideline development is part of the committee process in addition to SOGC council and editorial review... - Pre-conceptional vitamin/folic acid supplementation 2007: the use of folic acid in combination with a multivitamin supplement for the prevention of neural tube defects and other congenital anomaliesR Douglas Wilson
Philadelphia PA, USA
J Obstet Gynaecol Can 29:1003-26. 2007..OPTION: Supplementation with folic acid and vitamins is problematic, since 50% of pregnancies are unplanned, and women's health status may not be optimal when they conceive...