William A Wilmer
Affiliation: The Ohio State University
- Transcutaneous oxygen tension in patients with calciphylaxisW A Wilmer
Department of Internal Medicine, Division of Nephrology, Ohio State University, Columbus, OH, USA
Am J Kidney Dis 37:797-806. 2001..This study shows that TCPO(2) measurements may allow rapid and noninvasive screening for skin ischemia before the development of skin lesions in patients with calciphylaxis...
- Chronic exposure of human mesangial cells to high glucose environments activates the p38 MAPK pathwayW A Wilmer
Nephrology Division, Department of Internal Medicine, Heart Lung Research Institute, The Ohio State University College of Medicine, Columbus, Ohio, USA
Kidney Int 60:858-71. 2001..This current study investigated the mechanisms of HG-mediated activation of p38 MAPK in cultured human mesangial cells (HMCs) and the effects of p38 MAPK activation on the transcription factor activator protein-1 (AP-1)...
- Calciphylaxis: emerging concepts in prevention, diagnosis, and treatmentWilliam A Wilmer
Division of Nephrology, Department of Internal Medicine, Ohio State University College of Medicine and Public Health, Columbus, Ohio, USA
Semin Dial 15:172-86. 2002..Recent advances in diagnostic tools and therapeutic strategies have helped in the management of patients with calciphylaxis...
- PPAR-alpha ligands inhibit H2O2-mediated activation of transforming growth factor-beta1 in human mesangial cellsWilliam A Wilmer
Division of Nephrology, The Department of Internal Medicine, Dorothy M Davis Heart Lung Research Institute, The Ohio State University College of Medicine, Columbus, OH 43210, USA
Antioxid Redox Signal 4:877-84. 2002..These studies are the first to identify PPAR-alpha expression by HMC. The results of these studies suggest that TGF-beta1 expression mediated by oxidant stress may be suppressible by PPAR-alpha activation...
- Relapse or worsening of nephrotic syndrome in idiopathic membranous nephropathy can occur even though the glomerular immune deposits have been eradicatedChadwick E Barnes
Departments of Internal Medicine and Pathology, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
Nephron Clin Pract 119:c145-53. 2011..Relapse or worsening of nephrotic syndrome (NS) in idiopathic membranous nephropathy (IMN) is generally assumed to be due to recurrent disease. Here we document that often that may not be the case...
- 15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and deathBrad H Rovin
Department of Internal Medicine and Heart Lung Research Institute, Ohio State University School of Medicine and Public Health, Columbus, Ohio 43210, USA
Kidney Int 61:1293-302. 2002..To identify endogenous factors that may be responsible for regulating glomerular cell number, the effects of J-series cyclopentenone prostaglandins (PGs) on human glomerular mesangial cell proliferation and death were examined...
- Culture-negative peritoneal dialysis peritonitis associated with pancreaticoduodenocystotomy leak of a pancreas transplantLourdes T Terrado
Division of Nephrology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA
Am J Kidney Dis 41:E4-8. 2003..Peritoneal dialysis (PD) peritonitis is usually caused by infection and less commonly by a sterile inflammatory reaction...
- Management of glomerular proteinuria: a commentaryWilliam A Wilmer
Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio 43210 1250, USA
J Am Soc Nephrol 14:3217-32. 2003..This work is intended primarily for clinical nephrologists; therefore, each antiproteinuria intervention is described in practical detail...