Ian R Wickersham
Affiliation: The Salk Institute
- Retrograde neuronal tracing with a deletion-mutant rabies virusIan R Wickersham
Systems Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Rd, La Jolla, California 92037, USA
Nat Methods 4:47-9. 2007..The cells therefore fluoresce intensely, revealing fine dendritic and axonal structure with no background from partially or faintly labeled cells...
- Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neuronsIan R Wickersham
Systems Neurobiology, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
Neuron 53:639-47. 2007..This technology should enable a far more detailed understanding of neural connectivity than has previously been possible...
- Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virusNicholas R Wall
Systems Neurobiology Laboratories, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
Proc Natl Acad Sci U S A 107:21848-53. 2010..Furthermore, by expressing various transgenes from the rabies genome, this system also has the potential to allow manipulation of targeted neuronal circuits without perturbing neighboring cells...
- Retrograde tracing with recombinant rabies virus reveals correlations between projection targets and dendritic architecture in layer 5 of mouse barrel cortexDeLaine D Larsen
Systems Neurobiology Laboratories, The Salk Institute for Biological Studies, Neurosciences Graduate Program, University of California San Diego, La Jolla, CA, USA
Front Neural Circuits 1:5. 2007..These differences were revealed by the ability to completely label dendritic and axonal arbors in vivo and have not been apparent in previous studies using labeling in brain slices...