Research Topics
Genomes and Genes | Elizabeth M WatersSummaryAffiliation: The Rockefeller University Country: USA Publications
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Publications
Estrogen receptor alpha and beta specific agonists regulate expression of synaptic proteins in rat hippocampusElizabeth M Waters
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Brain Res 1290:1-11. 2009..Moreover, the effects of estradiol treatment on PSD-95 expression are consistent with a growing body of evidence that this postsynaptic protein is a key marker of estrogen action related to spine synapse formation...
Estrogen induces caspase-dependent cell death during hypothalamic developmentElizabeth M Waters
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10065, USA
J Neurosci 29:9714-8. 2009..Thus, in contrast to the more widespread neuroprotective actions of sex steroids in the mammalian nervous system, in the AVPV estrogen regulates dopaminergic neuron number through a caspase-dependent mechanism of apoptotic cell death...
Age- and hormone-regulation of opioid peptides and synaptic proteins in the rat dorsal hippocampal formationTanya J Williams
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY 10065, USA
Brain Res 1379:71-85. 2011..Moreover, they lend credence to the "window of opportunity" hypothesis during which hormone replacement can modulate hippocampal structure and circuitry to improve cognitive outcomes...
Cellular and subcellular localization of estrogen and progestin receptor immunoreactivities in the mouse hippocampusKatherine L Mitterling
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10065, USA
J Comp Neurol 518:2729-43. 2010....
Ovarian steroids alter mu opioid receptor trafficking in hippocampal parvalbumin GABAergic interneuronsAnnelyn Torres-Reveron
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 407 East 61st Street, New York, NY 10065, USA
Exp Neurol 219:319-27. 2009....
Ovarian steroids modulate leu-enkephalin levels and target leu-enkephalinergic profiles in the female hippocampal mossy fiber pathwayAnnelyn Torres-Reveron
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 411 East 69th Street, New York, NY 10021, USA
Brain Res 1232:70-84. 2008..The present studies indicate that estrogen can modulate LENK in subregions of the MF pathway in a dose-and time-dependent manner. These effects might be triggered by direct activation of ERbeta or PR in LENK-containing terminals...
Estrogen and aging affect the synaptic distribution of estrogen receptor β-immunoreactivity in the CA1 region of female rat hippocampusElizabeth M Waters
Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
Brain Res 1379:86-97. 2011..This suggests that synaptic ERβ may be a more responsive target to E, particularly in aged females...
Uncovering the mechanisms of estrogen effects on hippocampal functionJoanna L Spencer
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, 1300 York Avenue, New York, NY 10065, USA
Front Neuroendocrinol 29:219-37. 2008..Finally, estrogen may signal through both nuclear and extranuclear hippocampal estrogen receptors to achieve its downstream effects...
Distribution of phosphorylated TrkB receptor in the mouse hippocampal formation depends on sex and estrous cycle stageJoanna L Spencer-Segal
Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10021, USA
J Neurosci 31:6780-90. 2011..These findings suggest that presynaptic TrkB is positioned to modulate estradiol-mediated and BDNF-dependent synaptic plasticity. Furthermore, they suggest a novel role for TrkB in microglial function in the neuroimmune system...
BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal functionJoanna L Spencer
Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, USA
Proc Natl Acad Sci U S A 107:4395-400. 2010..The variant BDNF Val66Met should therefore be considered as a strong candidate for mediating genetic differences in ovarian steroid-related behavioral changes and disorders...
Angiotensin II-induced hypertension differentially affects estrogen and progestin receptors in central autonomic regulatory areas of female ratsTeresa A Milner
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 411 East 69th Street, New York, NY 10021, USA
Exp Neurol 212:393-406. 2008..Considering that ERalpha counteracts the central and peripheral effects of AngII, these receptor changes may underlie adaptive responses that protect females from the deleterious effects of hypertension...
Estrogen effects on the brain: actions beyond the hypothalamus via novel mechanismsBruce S McEwen
Laboratory of Neuroendocrinology, The Rockefeller University, Box 165, 1230 York Avenue, New York, NY 10065, USA
Behav Neurosci 126:4-16. 2012..This exciting and growing field involving many laboratories continues to reshape our ideas and approaches to neuroendocrinology both at the bench and the bedside...
Ultrastructural localization of extranuclear progestin receptors in the rat hippocampal formationElizabeth M Waters
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10065, USA
J Comp Neurol 511:34-46. 2008....
Degenerating processes identified by electron microscopic immunocytochemical methodsTeresa A Milner
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY, USA
Methods Mol Biol 793:23-59. 2011..The information obtained can be further refined through the use of dual immunolabeling, which can provide additional data on the phenotype of the degenerating process and inputs to the process...
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brainKaren Bulloch
Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10065, USA
J Comp Neurol 508:687-710. 2008..Collectively, these findings suggest a new member of the dendritic cell family residing among the heterogeneous microglia population...
Behavioral and biological effects of chronic S18986, a positive AMPA receptor modulator, during agingErik B Bloss
The Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10021, USA
Exp Neurol 210:109-17. 2008..These results provide a framework for further studies of the potentially beneficial effects of AMPAR modulators on brain aging...
Distribution of estrogen receptor β containing cells in the brains of bacterial artificial chromosome transgenic miceTeresa A Milner
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 407 East 61st Street, New York, NY 10065, USA
Brain Res 1351:74-96. 2010..These findings support the utility of Esr2 BAC transgenic reporter mice for future studies understanding the role of ERbeta in CNS function...
Accelerated ovarian failure: a novel, chemically induced animal model of menopauseTracey A Van Kempen
Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY 10065, USA
Brain Res 1379:176-87. 2011..e., a window of opportunity) during perimenopause for restoring ovarian hormones for the most efficacious effect on memory and mood disorders as well as other menopausal symptoms...
Steroid-induced hippocampal synaptic plasticity: sex differences and similaritiesRussell D Romeo
Laboratory of Neuroendocrinology, The Rockefeller University, Box 165, New York, NY 10021, USA
Neuron Glia Biol 1:219-29. 2004....
Extranuclear estrogen receptor beta immunoreactivity is on doublecortin-containing cells in the adult and neonatal rat dentate gyrusScott P Herrick
Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY 10021, USA
Brain Res 1121:46-58. 2006..These findings are consistent with data showing that estrogens can exert non-genomic effects directly and indirectly on newly generated cells in neonatal and adult rat dentate gyrus...
