Xin Shelley Wang

..To describe fatigue severity, fatigue interference, and associated factors in hematologic malignancies...

..0001). This longitudinal study suggests a role for over-expressed sTNF-R1 and IL-6 in the development of fatigue and other severe sickness symptoms during CXRT in patients with colorectal or esophageal cancer...

..We investigated the clinical benefit of SBRT for managing spinal metastases and reducing cancer-related symptoms...

....

..The authors report the development of an MDASI module for use in patients with gastrointestinal (GI) cancer (the MDASI-GI)...

..In multinational clinical trials, cultural and linguistic variations in patient-reported outcomes instruments could confound the interpretation of study results...

..However, the mechanism underlying the development of multiple symptoms has not been established...

..Pathophysiologic research in CRF could be applied in the clinic to improve CRF diagnosis and to enable administration of mechanism-driven interventions. A targeted intervention study with CRF as a primary end point also would be useful...

..However, translating patient-reported outcomes into useful prognostic information for individual patients has been problematic...

..We developed and validated a Filipino language version of the Brief Fatigue Inventory (BFI-F) for describing the prevalence and severity of fatigue among Filipino patients with cancer...

....

..We compared risk factors for high disease- and treatment-related symptom burden over 15 weeks of therapy in medically underserved patients with advanced non-small-cell lung cancer and in patients treated at a tertiary cancer center...

..These concepts open exciting new avenues for translational research in the pathophysiology and treatment of cancer-related symptoms...

..Remedial action should be taken, including increasing awareness of symptom management in medical staff and incorporating existing knowledge into routine clinical practice...

..Because disease-related and treatment-related symptoms most often occur in clusters, there is a global need for a standardized multiple-symptom assessment tool...

..In this phase 1/2 study, the authors tested the hypothesis that single-fraction stereotactic body radiotherapy (SBRT) for previously unirradiated spinal metastases is a safe, feasible, and efficacious treatment approach...

..This study examined whether at-home symptom monitoring plus feedback to clinicians about severe symptoms contributes to more effective postoperative symptom control...

..Both factor analysis and cluster analysis showed the consistency of the statistical structure of the English and Japanese versions, indicating the cross-cultural validity of the scale...

..This study explored the relationship between the M. D. Anderson Symptom Inventory (MDASI), an instrument measuring the severity of symptoms common to patients with cancer, and utility derived from the SF-36...

..Choosing an appropriate recall period for symptom assessment in a clinical trial is dependent on the design and purpose of the trial...

....

..The BFI-C is a valid, reliable instrument to measure the severity and impact of cancer-related fatigue among Chinese patients...

..Our results provide information that might guide the choice of recall period for cancer clinical trials with pain as a self-reported outcome...

..Results of the survey suggest specific training and research in symptom management that might improve end-of-life care for Chinese cancer patients...

..Although the majority of the psychiatric patients reported sleep disturbance, their sleep disturbance scores were not significantly associated with fatigue severity...

..Additionally, fatigue severity classification was explored using the BFI-J. The results indicated that the BFI-J is a brief, valid, and feasible measure of fatigue for use with Japanese cancer patients...

..To evaluate the outcomes associated with stereotactic body radiotherapy (SBRT) in the management of spinal metastases from renal cell carcinoma (RCC)...

....

..Cancer patients reported significantly greater symptom severity on multiple items than did the community sample. The MDASI-F is reliable and valid for evaluating cancer-related symptoms and their impact on Filipino cancer patients...

..The authors review a prospective series of spinal metastasis patients reirradiated with stereotactic body radiotherapy...

..These symptoms include pain, wasting, fatigue, cognitive impairment, anxiety, and depression, many of which co-occur. There is growing recognition that at least some of these symptoms may share common biologic mechanisms...

..We sought to validate a module of the M. D. Anderson Symptom Inventory (MDASI) developed specifically for patients with MM (MDASI-MM)...

..A representation of changes in multiple symptoms would clarify the impact of treatment and enhance the interpretation of cancer clinical trials for clinicians, patients, and those who make health care policy...

..To investigate whether symptom burden before and during preoperative chemoradiation therapy (CRT) for rectal cancer predicts for pathologic tumor response...

..10, CI=1.31-3.37), and belief that children are less sensitive to pain (OR=1.96, CI=1.02-3.76). The top barriers to optimal pediatric pain management were identified as fear of opioid addiction and inadequate knowledge of pain management...

..74). Although fatigue was not the major reason for an ER visit, single-item fatigue-severity screening demonstrated highly prevalent severe fatigue in sicker EC cancer patients and in those patients who also suffered from other symptoms...

..CONCLUSION: There is a leveling effect of lymphoma across gender on most tasks. The significant relations between physical performance tasks and fatigue are suggestive of the pervasive influence of fatigue on physical function...

..The BFI-T is reliable, valid, and sensitive for measuring cancer-related fatigue severity and interference among Taiwanese cancer patients...

..Symptoms other than their primary disease can interfere in the lives of terminal cancer patients. We sought to identify which of these symptoms is most important...

....

..The MDASI-T is a reliable, valid, and sensitive instrument for measuring the severity and interference with daily life of cancer-related symptoms among Taiwanese cancer patients...

..Our findings indicate that comorbidities should be considered when comparing fatigue data from the general population with data from patients...

..This study provides evidence that the MDASI-T is a reliable and valid instrument for measuring cancer-related symptoms in Taiwanese adolescents with cancer...

..Our study has shown that the BFI-K is a reliable, valid self-rating instrument in terms of its psychometric properties...

..Seventy-four percent of the patients in the Seoul sample had inadequate analgesia using the PMI. CONCLUSION: The BPI-K is a valid and useful instrument for assessing cancer pain and pain impact in Korea...

..The MDASI-K is a valid and reliable measure for assessing multiple symptoms in Korean cancer patients...

..To identify cancer distribution and treatment requirements, a questionnaire on cancer patients was conducted. It was our objective to validate a series of symptoms commonly used in traditional Chinese medicine (TCM)...

..The purposes of this study were to assess clinicians' (n = 250) current practices and attitudes about cancer pain management and to identify perceived concerns about and barriers to pain control in urban cancer-treatment settings in Korea...