Sa A Wang

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi request reprint Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components
    Sa A Wang
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Hematol 88:219-24. 2013
  2. doi request reprint Diagnosis of myelodysplastic syndromes in cytopenic patients
    Sa A Wang
    Department of Hematopathology, University of Texas, MD Anderson Cancer Center, Unit 72, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Hematol Oncol Clin North Am 25:1085-110, vii. 2011
  3. ncbi request reprint Erythroid proliferations in myeloid neoplasms
    Sa A Wang
    Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 43:153-64. 2012
  4. doi request reprint Myelodysplastic syndromes with deletions of chromosome 11q lack cryptic MLL rearrangement and exhibit characteristic clinicopathologic features
    Sa A Wang
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Leuk Res 35:351-7. 2011
  5. doi request reprint Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features
    S A Wang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Leukemia 24:740-7. 2010
  6. pmc Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats
    Sa A Wang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Haematologica 94:29-37. 2009
  7. ncbi request reprint Erythroid-predominant myelodysplastic syndromes: enumeration of blasts from nonerythroid rather than total marrow cells provides superior risk stratification
    Sa A Wang
    Department of Pathology, UMass Memorial Medical Center, University of Massachusetts, Worcester, MA, USA
    Mod Pathol 21:1394-402. 2008
  8. ncbi request reprint Immunophenotypic heterogeneity of normal plasma cells: comparison with minimal residual plasma cell myeloma
    Dingsheng Liu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Pathol 65:823-9. 2012
  9. pmc Precursor B-acute lymphoblastic leukemia occurring in patients with a history of prior malignancies: is it therapy-related?
    Guilin Tang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Haematologica 97:919-25. 2012
  10. doi request reprint Pure erythroid leukemia: a reassessment of the entity using the 2008 World Health Organization classification
    Wei Liu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Mod Pathol 24:375-83. 2011

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components
    Sa A Wang
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Hematol 88:219-24. 2013
    ..The presentation, treatment, and outcome of patients with SM-AHNMD is often dictated by the type of AHNMD...
  2. doi request reprint Diagnosis of myelodysplastic syndromes in cytopenic patients
    Sa A Wang
    Department of Hematopathology, University of Texas, MD Anderson Cancer Center, Unit 72, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Hematol Oncol Clin North Am 25:1085-110, vii. 2011
    ....
  3. ncbi request reprint Erythroid proliferations in myeloid neoplasms
    Sa A Wang
    Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 43:153-64. 2012
    ....
  4. doi request reprint Myelodysplastic syndromes with deletions of chromosome 11q lack cryptic MLL rearrangement and exhibit characteristic clinicopathologic features
    Sa A Wang
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Leuk Res 35:351-7. 2011
    ..These clinicopathological features are likely attributed to commonly deleted regions of 11q and their involved genes...
  5. doi request reprint Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features
    S A Wang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Leukemia 24:740-7. 2010
    ..97). We conclude that trisomy 11 in MDS correlates with clinical aggressiveness, may suggest an early/evolving AML with myelodysplasia-related changes and is best considered a high-risk cytogenetic abnormality in MDS prognostication...
  6. pmc Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats
    Sa A Wang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Haematologica 94:29-37. 2009
    ..However, the status of paroxysmal nocturnal hemoglobinuria clones in various categories of myelodysplastic syndrome and in other bone marrow disorders is not well-studied...
  7. ncbi request reprint Erythroid-predominant myelodysplastic syndromes: enumeration of blasts from nonerythroid rather than total marrow cells provides superior risk stratification
    Sa A Wang
    Department of Pathology, UMass Memorial Medical Center, University of Massachusetts, Worcester, MA, USA
    Mod Pathol 21:1394-402. 2008
    ..We conclude that in erythroid-predominant myelodysplastic syndrome, blast calculation as a proportion of marrow nonerythroid rather than total nucleated cells can better stratify patients into prognostically relevant groups...
  8. ncbi request reprint Immunophenotypic heterogeneity of normal plasma cells: comparison with minimal residual plasma cell myeloma
    Dingsheng Liu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Pathol 65:823-9. 2012
    ..With advances in multicolour flow cytometry and application of recently validated markers, PCM MRD may still be reliably distinguished from non-neoplastic plasma cells...
  9. pmc Precursor B-acute lymphoblastic leukemia occurring in patients with a history of prior malignancies: is it therapy-related?
    Guilin Tang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Haematologica 97:919-25. 2012
    ..Precursor B-acute lymphoblastic leukemia occurring in patients with a history of malignancies is uncommon, and this condition is not well understood...
  10. doi request reprint Pure erythroid leukemia: a reassessment of the entity using the 2008 World Health Organization classification
    Wei Liu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Mod Pathol 24:375-83. 2011
    ..These new assigned categories fail to capture the distinct features of PEL, where the phenotype of PEL correlates with a very complex karyotype and an extremely aggressive clinical course...
  11. doi request reprint Potential therapeutic biomarkers in plasma cell myeloma: a flow cytometry study
    Wenli Zheng
    Department of Hematopathology, The University of Texas M D, Anderson Cancer Center, Houston, TX, USA
    Cytometry B Clin Cytom 84:222-8. 2013
    ..To investigate the expression profile of potential therapeutic biomarkers in plasma cell myeloma (PCM) by multicolor flow cytometry analysis...
  12. pmc Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy
    Farhad Ravandi
    Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Blood 122:1214-21. 2013
    ..2). At 3 and 12 months, negative MRD by MFC was associated with improved survival (P = .04 and .001). MRD monitoring by PCR and MFC identifies patients who benefit from treatment intensification in first CR...
  13. doi request reprint Multi-color CD34⁺ progenitor-focused flow cytometric assay in evaluation of myelodysplastic syndromes in patients with post cancer therapy cytopenia
    Guilin Tang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Leuk Res 36:974-81. 2012
    ..With a median follow-up of 11 months, this assay demonstrated 89% sensitivity, 94% specificity, and 92% accuracy in establishing or excluding a diagnosis of MDS...
  14. doi request reprint Flow cytometric detection of peripheral blood involvement by mycosis fungoides and Sézary syndrome using T-cell receptor Vbeta chain antibodies and its application in blood staging
    Bo Feng
    Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Mod Pathol 23:284-95. 2010
    ....
  15. doi request reprint Clinicopathologic features of CD5-positive nodal marginal zone lymphoma
    Jesse Manuel Jaso
    The University of Texas MD Anderson Cancer Center, Dept of Hematopathology, Box 72, 1515 Holcombe Blvd, Houston, TX 77030 E mail
    Am J Clin Pathol 140:693-700. 2013
    ..To describe the clinicopathologic findings of seven patients with CD5-positive nodal marginal zone lymphoma (NMZL)...
  16. doi request reprint Therapy-related acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favorable outcome
    Steven A Gustafson
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Clin Pathol 131:647-55. 2009
    ..002). These findings suggest that t-AML-t(8;21) shares many features with de novo AML-t(8;21)(q22;q22), but affected patients have a worse outcome...
  17. ncbi request reprint Flow cytometric analysis of myelomonocytic cells by a pattern recognition approach is sensitive and specific in diagnosing myelodysplastic syndrome and related marrow diseases: emphasis on a global evaluation and recognition of diagnostic pitfalls
    Dariusz Stachurski
    Department of Pathology, UMass Memorial Medical Center, University of Massachusetts, Worcester, MA, USA
    Leuk Res 32:215-24. 2008
    ..Based on a global evaluation of myelomonocytic abnormalities, and recognition of diagnostic pitfalls and caveats, the pattern recognition approach of FCM is sensitive and reliable in diagnosing MDS and related myeloid diseases...
  18. doi request reprint Chronic basophilic leukemia: a rare form of chronic myeloproliferative neoplasm
    Guilin Tang
    Department of Pathology, University of Massachusetts Medical Center, Worcester, MA 01605, USA
    Hum Pathol 40:1194-9. 2009
    ..Conventional karyotyping revealed a t(5;12)(q31;p13). ETV6 but not PDGFRB rearrangement was detected by fluorescence in situ hybridization...
  19. ncbi request reprint Hypocellularity in myelodysplastic syndrome is an independent factor which predicts a favorable outcome
    Gang Yue
    Department of Pathology, UMass Memorial Medical Center, 3 Biotech, 1 Innovation Drive, University of Massachusetts, Worcester, MA 01605, USA
    Leuk Res 32:553-8. 2008
    ..01). In conclusion, our study demonstrated that hypocellular MDS has characteristic clinicopathologic features, and bone marrow hypocellularity in MDS is an independent factor which predicts a favorable outcome...
  20. pmc Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms
    Sa A Wang
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX
    Blood 123:2645-51. 2014
    ..The MDS/MPN-U category is heterogeneous, and patient risk can be further stratified by a number of clinicopathological parameters...
  21. pmc Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification
    Robert P Hasserjian
    Department of Pathology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Blood 115:1985-92. 2010
    ..Our findings suggest that AEL is in the continuum of MDS and AML with erythroid hyperplasia, where karyotype rather than an arbitrary blast cutoff represents the most important prognostic factor...
  22. doi request reprint Usefulness of flow cytometric immunophenotyping for bone marrow staging in patients with mantle cell lymphoma after therapy
    Wei Liu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Am J Clin Pathol 137:634-40. 2012
    ..We conclude that FCI is more sensitive than morphologic examination of BM at the time of restaging in patients with MCL and that positivity by only FCI in BM often correlates with concurrent disease or subsequent relapse...
  23. doi request reprint The utility of flow cytometric immunophenotyping in cytopenic patients with a non-diagnostic bone marrow: a prospective study
    Francoise Truong
    Department of Pathology, UMass Memorial Medical Center, University of Massachusetts School of Medicine, Worcester, MA, USA
    Leuk Res 33:1039-46. 2009
    ....
  24. doi request reprint High-level CD34 expression on megakaryocytes independently predicts an adverse outcome in patients with myelodysplastic syndromes
    Guilin Tang
    Department of Pathology, University of Massachusetts Medical Center, Worcester, MA 01605, USA
    Leuk Res 35:766-70. 2011
    ..Multivariate analysis indicated that the expression of CD34 on megakaryocytes could be a strong and an independent poor prognostic factor in MDS, with a hazard ratio of 2.53...
  25. ncbi request reprint Cytogenetic risk stratification of 417 patients with chronic myelomonocytic leukemia from a single institution
    Guilin Tang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Am J Hematol 89:813-8. 2014
    ..Our study results strongly advocate for the incorporation of cytogenetic information in the risk model for CMML. Am. J. Hematol. 89:813-818, 2014. © 2014 Wiley Periodicals, Inc. ..
  26. ncbi request reprint The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes
    Bin Fu
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 72, Houston, TX 77030, USA
    Ann Hematol 92:1335-43. 2013
    ..However, unlike the situation in patients with primary MDS, moderate/severe BM fibrosis does not add additional risk to patients with therapy-related MDS...
  27. ncbi request reprint Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma with a complex karyotype and cryptic 3' ALK gene insertion to chromosome 4 q22-24
    Dariusz Stachurski
    Department of Pathology, University of Massachusetts Medical Center, Worcester, MA 01605, USA
    Hum Pathol 38:940-5. 2007
    ..This case indicates that ALK-positive DLBCL is more heterogeneous at the cytogenetic/molecular level than previously recognized...
  28. ncbi request reprint Usefulness of CD11a and CD18 in flow cytometric immunophenotypic analysis for diagnosis of acute promyelocytic leukemia
    Yi Zhou
    Dept of Hematopathology, Unit 72, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Clin Pathol 138:744-50. 2012
    ..These data compare favorably with the combination of HLA-DR-, CD34-, and CD117+ for APL diagnosis, which had a sensitivity of 64% in this study...
  29. doi request reprint The oncofetal protein IMP3: a novel molecular marker to predict aggressive meningioma
    Suyang Hao
    Department of Pathology, University of Massachusetts Medical Center, Worcester, USA
    Arch Pathol Lab Med 135:1032-6. 2011
    ..One of the major clinical challenges is to predict recurrence of meningioma. Recently, we have found that IMP3, an oncofetal RNA-binding protein, is a biomarker to predict aggressive tumors...
  30. doi request reprint Cytogenetic abnormalities in a series of 1,029 patients with primary myelodysplastic syndromes: a report from the US with a focus on some undefined single chromosomal abnormalities
    Olga Pozdnyakova
    Department of Pathology, University of Massachusetts Memorial Medical Center, University of Massachusetts School of Medicine, Worcester, MA, USA
    Cancer 113:3331-40. 2008
    ..In addition, the emerging therapeutic agents may change the natural course of disease in patients with MDS and the cytogenetic impact on risk stratification...
  31. ncbi request reprint CD30 expression in high-risk acute myeloid leukemia and myelodysplastic syndromes
    Wenli Zheng
    Department of Hematopathology, MD Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA
    Clin Lymphoma Myeloma Leuk 13:307-14. 2013
    ..We assessed for CD30 expression in patients with acute myeloid leukemia (AML) or high-grade myelodysplastic syndrome (MDS) to examine the possibility that anti-CD30 could be targeted therapy in these patients...
  32. ncbi request reprint Aberrant underexpression of CD81 in precursor B-cell acute lymphoblastic leukemia: utility in detection of minimal residual disease by flow cytometry
    Tariq Muzzafar
    Dept of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Pathol 132:692-8. 2009
    ..Decreased CD81 expression is a sensitive and specific marker for residual pre-B-ALL, even in a background of hematogones, making CD81 a useful addition to a panel for MRD detection by FC...
  33. pmc Acute myeloid leukemia (AML) with erythroid predominance exhibits clinical and molecular characteristics that differ from other types of AML
    Zhuang Zuo
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 7:e41485. 2012
    ....
  34. doi request reprint Transient/reversible ring sideroblasts in bone marrow of patients post cytotoxic therapies for primary malignancies
    Chi Young Ok
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Leuk Res 35:1605-10. 2011
    ..Four patients with transient/reversible RS received α-interferon therapy which may contribute to RS formation in this setting...
  35. doi request reprint Prognostic significance of immunophenotypic and karyotypic features of Philadelphia positive B-lymphoblastic leukemia in the era of tyrosine kinase inhibitors
    Jesse Jaso
    Department of Pathology, The University of Texas Medical Center Health Sciences Center, Houston, Texas, USA
    Cancer 117:4009-17. 2011
    ..The prognostic significance of these parameters was assessed in the context of intensive tyrosine kinase inhibitor (TKI)-based chemotherapy...
  36. doi request reprint Interphase FISH in plasma cell dyscrasia: increase in abnormality detection with plasma cell enrichment
    Olga Pozdnyakova
    Department of Pathology, UMass Memorial Medical Center, Worcester, MA 01605, USA
    Cancer Genet Cytogenet 189:112-7. 2009
    ..We conclude that the plasma cell enrichment step for iFISH should be incorporated into the routine cytogenetic work-up for all patients with plasma cell neoplasms...
  37. doi request reprint A comparative analysis of lymphatic vessel density in ovarian serous tumors of low malignant potential (borderline tumors) with and without lymph node involvement
    Oluwole Fadare
    Department of Pathology, Wilford Hall Medical Center, Lackland AFB, San Antonio, Texas 78236, USA
    Int J Gynecol Pathol 27:483-90. 2008
    ..We discuss the possibility that nodal deposits may represent metastatic disease from secondary tumor implants...
  38. ncbi request reprint Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications
    Shi Wang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1439, USA Department of Pathology, National University Hospital, 119074, Singapore
    Hum Pathol 44:2658-67. 2013
    ..These findings suggest a common clonal origin for the FL and MCL components in both cases. ..
  39. ncbi request reprint Bone marrow fibrosis in patients with primary myelodysplastic syndromes has prognostic value using current therapies and new risk stratification systems
    Bin Fu
    1 Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 2 Department of Hematology, Central South University Xiangya Hospital, Changsha, China
    Mod Pathol 27:681-9. 2014
    ..Inclusion of bone marrow fibrosis in patient assessment may further aid in risk-adapted therapeutic decisions. ..
  40. pmc MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program
    Zijun Y Xu-Monette
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
    Blood 122:2630-40. 2013
    ....
  41. ncbi request reprint Chronic myelomonocytic leukemia evolving from preexisting myelodysplasia shares many features with de novo disease
    Sa A Wang
    Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01605, USA
    Am J Clin Pathol 126:789-97. 2006
    ..These findings indicate that in some cases of otherwise typical MDS, the progenitor cells may have some capacity for monocytic proliferation at diagnosis and manifest rapid disease progression once a monocytic proliferation supervenes...
  42. ncbi request reprint Homozygous inv(11)(q21q23) and MLL gene rearrangement in two patients with myeloid neoplasms
    Guilin Tang
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center Houston, TX 77030, USA
    Int J Clin Exp Pathol 7:3196-201. 2014
    ..Mastermind like 2 gene was identified as MLL partner gene in one case. To our knowledge, homozygous inv(11)(q21q23) with two MLL genes rearrangement are extremely rare; it is likely a result of acquired uniparental disomy. ..
  43. doi request reprint High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearrangements and a poor prognosis
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 61:945-54. 2012
    ..At a haematopathology workshop, experts had suggested the term 'high-grade B cell lymphoma, unclassifiable, with blastoid features', and recommended further studies...
  44. ncbi request reprint Clinically silent clonal cytogenetic abnormalities arising in patients treated for lymphoid neoplasms
    Guilin Tang
    Department of Hematopathology, UT MD Anderson Cancer Center, Houston, TX, USA Electronic address
    Leuk Res 38:896-900. 2014
    ..We conclude that the occurrence of CCA is not always associated with t-MN. Clinical correlation is essential to guide a proper management of these patients. ..
  45. ncbi request reprint The effect of peritransplant minimal residual disease in adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation
    Yi Zhou
    Department of Hematopathology, The University of Texas, M D Anderson Cancer Center, Houston, TX
    Clin Lymphoma Myeloma Leuk 14:319-26. 2014
    ..However, many ALL patients relapse after HSCT. There has been a continuing effort to improve identification of patients at high risk of relapse, with the goal of early intervention to improve outcome...
  46. ncbi request reprint Improved early outcomes using a T cell replete graft compared with T cell depleted haploidentical hematopoietic stem cell transplantation
    Stefan O Ciurea
    Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M D Anderson Cancer Center, Houston, USA
    Biol Blood Marrow Transplant 18:1835-44. 2012
    ..These results indicate that a TCR graft followed by effective control of GVHD posttransplantation may lower NRM and improve survival after haploidentical SCT...
  47. doi request reprint Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
    Yi Zhou
    Department of Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA
    Mod Pathol 25:237-45. 2012
    ..The fact that therapy-related myeloid neoplasms can directly emerge from 'prolonged myelosuppression' warrants a bone marrow examination to rule out therapy-related myeloid neoplasms in this clinical setting...
  48. doi request reprint Eosinophilia with FIP1L1-PDGFRA fusion in a patient with chronic myelomonocytic leukemia
    Victor Zota
    Department of Pathology, University of Massachusetts Memorial Medical Center, University of Massachusetts, Worcester, MA, USA
    J Clin Oncol 26:2040-1. 2008
  49. doi request reprint The expression of cytokeratin 5/6 in invasive lobular carcinoma of the breast: evidence of a basal-like subset?
    Oluwole Fadare
    Department of Pathology, Wilford Hall Medical Center, Lackland AFB, TX 78236, USA
    Hum Pathol 39:331-6. 2008
    ..Future studies are required to define the prognostic significance of CK5/6 expression in ILCs...
  50. doi request reprint Clinicopathological features of extramedullary recurrence/relapse of multiple myeloma
    Jan Cerny
    Division of Hematology Oncology, Department of Internal Medicine, UMass Memorial Medical Center, University of Massachusetts School of Medicine, Worcester, MA 01605, USA
    Eur J Haematol 81:65-9. 2008
    ..Our case series shows that extramedullary relapse of MM is characterized by high-grade histology, loss of CD56 expression, frequent resistance to current therapeutic regimens, aggressive biological behavior, and very short survival...
  51. ncbi request reprint Mosaic tetraploidy and transient GFI1 mutation in a patient with severe chronic neutropenia
    Jessica C Hochberg
    Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Pediatr Blood Cancer 50:630-2. 2008
    ..We speculate that an underlying genetic defect, inherited in an autosomal dominant pattern, leads to both disordered mitosis and neutropenia in this kindred...
  52. pmc Donor-specific anti-HLA Abs and graft failure in matched unrelated donor hematopoietic stem cell transplantation
    Stefan O Ciurea
    Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Blood 118:5957-64. 2011
    ..1%; P < .0001) and higher in women with 1 (P = .008) and 2 or more pregnancies (P = .0003) than in men. We conclude that the presence of anti-DPB1 DSAs is associated with graft failure in MUD hematopoietic stem cell transplantation...
  53. doi request reprint Lymphovascular space invasion does not predict vaginal relapses in stage I endometrioid adenocarcinoma of the endometrium
    Laurephile Desrosiers
    Department of Pathology, University of Massachusetts Medical Center, Worcester, MA 01605, USA
    Ann Diagn Pathol 12:112-7. 2008
    ..However, LVSI does not denote an increased likelihood of vaginal recurrences in S1EE. The presence of LVSI should not, in of itself, alter clinical staging, or trigger unnecessary therapeutic intervention...
  54. ncbi request reprint Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study
    Hagop Kantarjian
    Department of Leukemia, MD Anderson Cancer Center, Houston, TX 77030, USA
    Lancet Oncol 13:403-11. 2012
    ..CD22 is highly expressed in patients with ALL. Inotuzumab ozogamicin is a CD22 monoclonal antibody conjugated to the toxin calecheamicin. We did a phase 2 study to assess the efficacy of this antibody...
  55. ncbi request reprint Splenic marginal zone lymphoma with micronodular T-cell rich B-cell lymphoma
    Sa A Wang
    Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 30:128-32. 2006
    ..We describe a unique case of splenic marginal zone lymphoma associated with micronodular T cell/histiocyte-rich large B-cell lymphoma in the red pulp, a combination that has not previously reported in the literature...
  56. ncbi request reprint Gastrointestinal endoscopic findings in men with unexplained anemia and low normal ferritin values
    Sa A Wang
    Department of Pathology, University of Massachusetts Medical Center, Worcester, Massachusetts, USA
    Am J Hematol 81:324-7. 2006
    ..The diagnostic yield of endoscopy in patients with anemia, no GI symptoms or signs, and low normal ferritin is not known...
  57. ncbi request reprint Lobular intraepithelial neoplasia [lobular carcinoma in situ] with comedo-type necrosis: A clinicopathologic study of 18 cases
    Oluwole Fadare
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    Am J Surg Pathol 30:1445-53. 2006
    ..However, because classic LIN with necrosis is apparently rare in its pure form, reexcision is recommended when this lesion is detected in isolation in a core biopsy...
  58. doi request reprint Clinicopathologic features associated with cytohistologic noncorrelation in the diagnosis of cervical dysplasia: a study of concurrently obtained samples
    Oluwole Fadare
    Department of Pathology, Wilford Hall Medical Center, Lackland AFB, TX 78236, USA
    Int J Surg Pathol 17:31-7. 2009
    ..03), consistent with smaller extent of disease. These findings further illustrate that lesional factors are important potential contributors to the false-negative rate of the Papanicolaou test...