Research Topics
Species | Paul E WakelySummaryAffiliation: The Ohio State University Country: USA Publications
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Publications
Primary effusion lymphoma: cytopathologic diagnosis using in situ molecular genetic analysis for human herpesvirus 8Paul E Wakely
Department of Pathology, The Ohio State University, Columbus, Ohio 43210, USA
Mod Pathol 15:944-50. 2002..Definitive diagnosis of primary effusion lymphoma is possible directly from cytologic smears/cell block by combining cytologic morphology with reverse transcriptase in situ polymerase chain reaction detection of human herpesvirus-8...
Phase II clinical trial of sorafenib in metastatic medullary thyroid cancerElaine T Lam
Departments of Internal Medicine, Center for Biostatistics, The Ohio State University, Columbus, OH, USA
J Clin Oncol 28:2323-30. 2010..Sorafenib, a multikinase inhibitor targeting Ret and VEGFR, showed antitumor activity in preclinical studies of MTC...
Fine-needle aspiration biopsy of the distal extremities: a study of 141 casesJoseph D Jakowski
Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
Am J Clin Pathol 133:224-31. 2010..Seven nonsarcomas included melanoma (3), metastatic squamous carcinoma (2), and malignant lymphoma (2). An FNAB-procured cytopathologic diagnosis is clinically reliable in a high percentage of distal extremity mass lesions...- Fine-needle aspiration biopsy of high-grade sarcoma: a report of 107 casesRanleigh Fleshman
Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 4320, USA
Cancer 111:491-8. 2007..To the authors' knowledge, few studies exist demonstrating the reliability of fine-needle aspiration (FNA) biopsy for high-grade sarcoma (HGS)... - Fine needle aspiration for clinical triage of extremity soft tissue massesVincent Y Ng
Department of Orthopaedics, Ohio State University Medical Center, 1050 Doan Hall, 410 West 10th Avenue, Columbus, OH, 43210, USA
Clin Orthop Relat Res 468:1120-8. 2010..Numerous reports describe its use with metastatic or recurrent lesions, but FNAC is less accepted for primary lesions... - MicroRNA signature in thyroid fine needle aspiration cytology applied to "atypia of undetermined significance" casesRulong Shen
Department of Pathology, Arthur G James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA
Thyroid 22:9-16. 2012..We selected eight miRs (miR-146b, -221, -187, -197, -346, -30d, -138, and -302c) to examine the potential use of miRs to supplement diagnostic cytology in cases designated as "atypia of undetermined significance.".. - Lipoblastic nerve sheath tumors: report of a distinctive variant of neural soft tissue neoplasm with adipocytic differentiationJose Antonio Plaza
Department of Pathology, Division of Anatomic Pathology, Ohio State University, Columbus, USA
Am J Surg Pathol 30:337-44. 2006..Neurogenic tumors should be added in the differential diagnosis of spindle cell tumors capable of displaying prominent signet-ring cell features... - Small cell osteosarcoma: cytopathologic characteristics and differential diagnosisJustin A Bishop
Department of Pathology, The Johns Hopkins Hospital, 600 N Wolfe St, Path 406, Baltimore, MD 21287, USA
Am J Clin Pathol 133:756-61. 2010..Correlation with radiographic findings and ancillary tests can aid in definitive diagnosis... - Local recurrence rate of fine-needle aspiration biopsy in primary high-grade sarcomasBenjamin H Kaffenberger
The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
J Surg Oncol 101:618-21. 2010..Our objective was to determine whether FNAB could be linked to an increased rate of local recurrence... - Fine needle aspiration in the diagnosis of thymic epithelial neoplasmsPaul E Wakely
Department of Pathology, Ohio State University College of Medicine, 414 Doan Hall, 410 West 10th Avenue, Columbus, OH 43210, USA
Hematol Oncol Clin North Am 22:433-42. 2008..Separation of moderately differentiated neuroendocrine carcinoma from poorly differentiated small cell neuroendocrine carcinomas is generally not possible... - Radiofrequency ablation of invasive breast carcinoma followed by delayed surgical excisionWilliam E Burak
Department of Surgical Oncology, Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
Cancer 98:1369-76. 2003..The current study was undertaken to determine the feasibility of treating small breast malignancies with RFA and to evaluate the postablation magnetic resonance imaging scans (MRI) and histologic findings... - Cytopathology-histopathology of the mediastinum II. Mesenchymal, neural, and neuroendocrine neoplasmsPaul E Wakely
Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
Ann Diagn Pathol 9:24-32. 2005..The purpose of this review is to focus on the shared and dissimilar morphologic features of this subset of neoplasms to improve diagnostic correlation between the two... - Sclerosing epithelioid fibrosarcoma of the oral cavityCamille T Elkins
Department of Pathology, The Ohio State University College of Medicine, 414 Doan Hall, 410 West 10th Avenue, Columbus, OH 43210, USA
Head Neck Pathol 5:428-31. 2011.... - High-grade urothelial carcinoma of the renal pelvis: clinicopathologic study of 108 cases with emphasis on unusual morphologic variantsDelia Perez-Montiel
Department of Pathology, Ohio State University Medical Center, The Ohio State University, University Hospital, Columbus, OH 43210, USA
Mod Pathol 19:494-503. 2006.... - Cytopathologic features of olfactory neuroblastomaSepi Mahooti
Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
Cancer 108:86-92. 2006..Minus such a clinical context, aspirates of metastatic ONB may be mistaken for metastatic pulmonary small cell NEC, cutaneous neuroendocrine (Merkel cell) carcinoma, and even small cell lymphoma... - Malignant solitary fibrous tumor: cytopathologic findings and differential diagnosisJustin A Bishop
Department of Pathology, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
Cancer Cytopathol 118:83-9. 2010..Malignant solitary fibrous tumors (SFTs) are extremely uncommon and poorly understood mesenchymal neoplasms. There are only rare published accounts of the cytopathologic features of these tumors, prompting the current study... - Cytopathology of thymic epithelial neoplasmsPaul E Wakely
Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
Semin Diagn Pathol 22:213-22. 2005..Thymic neuroendocrine carcinomas (NEC) are also cytologically identical to their more common pulmonary sites of origin, but identification of moderately-differentiated NEC is generally not possible... - Amyloidomas of soft parts: diagnosis by fine-needle aspirationCamille T Elkins
Department of Pathology, The Ohio State University, College of Medicine, Columbus, OH 43210, USA
Diagn Cytopathol 40:E126-30. 2012..Unlike prior assertions to the contrary, a diagnosis of amyloidoma is possible using FNA cytopathology even in patients without a known underlying amyloidogenic disorder... - The cytopathology of malignant peripheral nerve sheath tumor: a report of 55 fine-needle aspiration casesPaul E Wakely
Department of Pathology, Wexner Medical Center, Ohio State University, Columbus, USA
Cancer Cytopathol 120:334-41. 2012..Because of this, the fine-needle aspiration (FNA) cytopathology of MPNST is extremely challenging. In the current study, the authors review their FNA experience with this neoplasm... - Head and neck solitary fibrous tumors: diagnostic and therapeutic challengesSarah N Bowe
Department of Otolaryngology Head and Neck Surgery, The Ohio State University Medical Center, Columbus, USA
Laryngoscope 122:1748-55. 2012..The purpose of this study was to analyze the diagnostic and therapeutic challenges of this rare disease while reporting the largest head and neck case series... - An uncommon type of adrenal incidentaloma: a case report of a schwannoma of the adrenal medulla with cytological, histological, and ultrastructural correlationJoseph D Jakowski
Department of Pathology, Broady School of Medicine, East Carolina University, Greenville, NC 27834, USA
Ann Diagn Pathol 12:356-61. 2008..A review of the histogenesis and differential diagnosis of this common nerve sheath tumor in this unusual location is discussed... - A case report of anthracosilicotic spindle-cell pseudotumor of mediastinal lymph node: cytologic diagnosis by endoscopic ultrasound-guided fine-needle aspirationLinda R Varghese
Department of Pathology, Hennepin County Medical Center, Minneapolis, Minnesota, USA
Diagn Cytopathol 33:268-72. 2005..Electron microscopy was confirmatory and a diagnosis of anthracosilicotic spindle-cell pseudotumor was made. To the best of our knowledge, fine-needle aspiration cytology findings of this lesion have not been reported... - Sclerosing paraganglioma: report of 19 cases of an unusual variant of neuroendocrine tumor that may be mistaken for an aggressive malignant neoplasmJose Antonio Plaza
Department of Pathology, Ohio State University Medical Center, 410 West 10th Avenue, Columbus, OH 43210, USA
Am J Surg Pathol 30:7-12. 2006..Sclerosing paraganglioma should be included in the differential diagnosis of sclerosing lesions of the head and neck region and mediastinum. Appropriate immunohistochemical stains may be of aid for establishing the correct diagnosis... - Cytopathology of extraskeletal myxoid chondrosarcoma: report of 8 casesJoseph D Jakowski
Department of Pathology, College of Medicine, Ohio State University, Columbus, Ohio 43210, USA
Cancer 111:298-305. 2007.... - Primary intrathoracic low-grade fibromyxoid sarcomaJoseph D Jakowski
Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
Hum Pathol 39:623-8. 2008..Low-grade fibromyxoid sarcoma is probably an underrecognized intrathoracic neoplasm and should be considered in the differential diagnosis of spindle cell neoplasms of the mediastinum, pleura, heart, and lungs... - Oncocytic and oncocyte-like lesions of the head and neckPaul E Wakely
Department of Pathology, Ohio State University, College of Medicine, Columbus, OH 43210, USA
Ann Diagn Pathol 12:222-30. 2008..Correlating the fine-needle aspiration cytology and histology of both oncocytic and oncocyte-like neoplasms can assist in avoiding interpretive pitfalls among these lesions... - Interinstitutional consultation in fine-needle aspiration cytopathology: a study of 742 casesPhilip E Bomeisl
Department of Pathology, Ohio State University, College of Medicine, Columbus, Ohio 43210, USA
Cancer 117:237-46. 2009..However, to the authors' knowledge, few studies exist regarding this practice within cytopathology and specifically within fine-needle aspiration cytology (FNAC)... - Phase II trial of sorafenib in metastatic thyroid cancerRichard T Kloos
Ohio State University, Department of Internal Medicine, Molecular Virology, Immunology, and Genetics, Pathology, Radiology, Center for Biostatistics, Ohio State University, Columbus, OH 43210, USA
J Clin Oncol 27:1675-84. 2009..Based on the pivotal role of Ras-Raf-MAP-ERK signaling and vascular endothelial growth factor (VEGF) in papillary thyroid cancer (PTC), we conducted a phase II clinical trial of sorafenib targeting RAF and VEGF receptor kinases in PTC... - Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimensBenjamin N Christopher
Department of Ophthalmology, The Ohio State University, Columbus, OH, USA
Exp Eye Res 93:720-5. 2011..The DNA obtained is of sufficient quality to carry out genotyping for markers on chromosome 3, 6 and 8, as well as screening for somatic mutations in GNAQ and GNA11 genes... - Cytopathology of alveolar soft part sarcoma: a report of 10 casesPaul E Wakely
Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio, USA
Cancer 117:500-7. 2009..The objectives of the current study were to evaluate the cytomorphology of 10 ASPS cases on fine-needle aspiration (FNA) or imprint cytology, review the literature, and highlight potential diagnostic pitfalls... - Oral contraceptive pills are associated with artifacts in ThinPrep Pap smears that mimic low-grade squamous intraepithelial lesionsCarl Morrison
Department of Pathology, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
Cancer 99:75-82. 2003..These artifacts may reflect pressure-induced alteration of glycogen. PAS analysis and, more directly, HPV testing by in situ hybridization can help differentiate this mimicking from actual LGSILs... - Nodular fasciitis of the hand: a potential diagnostic pitfall in fine-needle aspiration cytopathologyJose A Plaza
Department of Pathology, The Ohio State University College of Medicine, Columbus 43210, USA
Am J Clin Pathol 123:388-93. 2005..All lesions eventually were diagnosed as nodular fasciitis after thorough histologic and immunohistologic evaluation. Nodular fasciitis remains a difficult diagnosis by FNAB, particularly when it occurs in locations such as the hand... - Intraarticular fibroma of tendon sheathMichael J Griesser
Department of Orthopaedics, The Ohio State University, Columbus, OH, USA
Indian J Orthop 45:276-9. 2011..Additionally, he has demonstrated no signs of recurrence. We report a case of fibroma of the tendon sheath originating from the synovial membrane of the joint capsule of the knee... - Rhabdomyomatous well-differentiated liposarcoma arising in giant fibrovascular polyp of the esophagusJoseph D Jakowski
Department of Pathology, Ohio State University, College of Medicine, Columbus, OH 43210, USA
Ann Diagn Pathol 13:263-8. 2009..To date, no previously reported giant fibrovascular polyp case has described a liposarcoma with rhabdomyomatous change... - Cytopathology-histopathology of the mediastinum: epithelial, lymphoproliferative, and germ cell neoplasmsPaul E Wakely
Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
Ann Diagn Pathol 6:30-43. 2002..This report focuses on the salient cytopathologic features of epithelial, lymphoid, and germ cell tumors of the mediastinum and correlates the cytomorphology with their histologic equivalent... - Fine-needle aspiration cytology of sclerosing perineuriomaLawrence H Lee
Departments of Pathology and Orthopedics, Ohio State University College of Medicine, Columbus, OH, USA
Ann Diagn Pathol 8:80-6. 2004..We report the fine needle aspiration cytopathology of sclerosing perineurioma, discuss potential pitfalls in cytologic interpretation, and compare the aspirate with the corresponding resection specimen... - Cytopathology of malignant melanoma in conventional and liquid-based smearsCarl Morrison
Department of Pathology, Ohio State University College of Medicine, Columbus 43210, USA
Am J Clin Pathol 118:435-41. 2002..With the exception of melanin, direct comparison of liquid-based and conventional smears showed higher cellularity in the former as the only difference... - Fine needle aspiration biopsy of gastrointestinal stromal tumor presenting as an umbilical mass (Sister Mary Joseph's Nodule)Donizete Scudeler
Department of Pathology, , Botucatu 01318-901, Brazil
Ann Diagn Pathol 10:100-3. 2006..Gastrointestinal stroma tumor involving the umbilicus is exceedingly uncommon and only rarely presents in this fashion. The cytomorphological features, differential diagnosis, and comparison with the tissue specimen are made...