Francisco Vega

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Br J Haematol 142:216-26. 2008
  2. doi request reprint Side population of a murine mantle cell lymphoma model contains tumour-initiating cells responsible for lymphoma maintenance and dissemination
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cell Mol Med 14:1532-45. 2010
  3. doi request reprint Angioimmunoblastic T-cell lymphoma in bone marrow: a morphologic and immunophenotypic study
    Faisal A Khokhar
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 41:79-87. 2010
  4. doi request reprint Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma
    Rajesh R Singh
    Department of Hematopathology and School of Health Sciences, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer Res 69:2550-8. 2009
  5. doi request reprint Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas
    Elias Drakos
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 42:1117-24. 2011
  6. pmc Quantification of bcl-2/JH fusion sequences and a control gene by multiplex real-time PCR coupled with automated amplicon sizing by capillary electrophoresis
    Beatriz Sanchez-Vega
    Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston 77030 4095, Texas, USA
    J Mol Diagn 4:223-9. 2002
  7. doi request reprint Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma
    Ji Eun Kim
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Mod Pathol 22:1312-20. 2009
  8. pmc Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols
    Wesley Greaves
    Department of Hematopathology, Unit 72, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA
    J Hematol Oncol 5:47. 2012
  9. pmc Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma
    Changju Qu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Blood 121:4718-28. 2013
  10. pmc Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
    Wesley O Greaves
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 42:1643-52. 2011

Collaborators

Detail Information

Publications49

  1. doi request reprint Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Br J Haematol 142:216-26. 2008
    ..In conclusion, SMZL, but not NMZL, demonstrates large genomic imbalances and frequent loss of the 7q31.32 and 7q36.2 regions involving POT1 and SHH, respectively. In NMZL, loss of FADD and gain of GLI1 are frequent events...
  2. doi request reprint Side population of a murine mantle cell lymphoma model contains tumour-initiating cells responsible for lymphoma maintenance and dissemination
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cell Mol Med 14:1532-45. 2010
    ....
  3. doi request reprint Angioimmunoblastic T-cell lymphoma in bone marrow: a morphologic and immunophenotypic study
    Faisal A Khokhar
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 41:79-87. 2010
    ..By contrast, programed death-1 immunohistochemical staining and double labeling using antibodies specific for BCL-6 and CD3 were helpful in appreciating the follicular T-helper cell immunophenotype of angioimmunoblastic T-cell lymphoma...
  4. doi request reprint Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma
    Rajesh R Singh
    Department of Hematopathology and School of Health Sciences, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer Res 69:2550-8. 2009
    ..There is a positive synergistic effect between the SHH/GLI1 and PI3K/AKT pathways that contributes to the lymphomagenic effect of NPM-ALK...
  5. doi request reprint Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas
    Elias Drakos
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 42:1117-24. 2011
    ..9, P < .0001). These data provide evidence that serine 194 phosphorylated Fas-associated death domain protein is involved in the proliferation of normal and neoplastic B cells and has features of a novel proliferation marker...
  6. pmc Quantification of bcl-2/JH fusion sequences and a control gene by multiplex real-time PCR coupled with automated amplicon sizing by capillary electrophoresis
    Beatriz Sanchez-Vega
    Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston 77030 4095, Texas, USA
    J Mol Diagn 4:223-9. 2002
    ..This multiplex PCR assay is equally sensitive to previous assays, allows more accurate quantification of bcl-2/JH fusion sequences, and is more convenient...
  7. doi request reprint Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma
    Ji Eun Kim
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Mod Pathol 22:1312-20. 2009
    ..These findings also provide evidence that dysregulation of the SHH pathway may be involved in the pathogenesis of diffuse large B-cell lymphoma...
  8. pmc Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols
    Wesley Greaves
    Department of Hematopathology, Unit 72, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA
    J Hematol Oncol 5:47. 2012
    ..ATP-binding cassette (ABC) transporters confer multidrug resistance in various cancers and ABCC1 overexpression has been shown to contribute to drug resistance in the CHL cell line, KMH2...
  9. pmc Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma
    Changju Qu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Blood 121:4718-28. 2013
    ..This signaling cascade contributes to the survival of DLBCL and may serve as a potential target for combination therapies in DLBCL...
  10. pmc Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
    Wesley O Greaves
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 42:1643-52. 2011
    ..Our data provide a rationale to further investigate the biologic significance of glioma-associated oncogene homologue 3 in classical Hodgkin lymphoma biology...
  11. ncbi request reprint Tissue-specific function of lymph node fibroblastic reticulum cells
    Francisco Vega
    Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Pathobiology 73:71-81. 2006
    ..We present the first characterization of the cytokine expression pattern of lymph node fibroblastic reticulum cells (FRC), which are the stromal cells responsible for maintaining the highly structured nodal reticular fiber framework...
  12. pmc Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways
    Lan V Pham
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Blood 117:200-10. 2011
    ..These results further elucidate mechanisms involved in abnormal NF-κB activation in DLBCL, and should contribute to better future therapeutic approaches for patients with DLBCL...
  13. ncbi request reprint The stromal composition of malignant lymphoid aggregates in bone marrow: variations in architecture and phenotype in different B-cell tumours
    Francisco Vega
    Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Br J Haematol 117:569-76. 2002
    ..In FL, expression of follicular dendritic cell-associated markers is modulated in pre-existing marrow stromal cells...
  14. doi request reprint Nodular lymphocyte predominant Hodgkin lymphoma with clusters of LP Cells, acute inflammation, and fibrosis: a syncytial variant
    Elias Drakos
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 33:1725-31. 2009
    ..Recognition of this rare variant, facilitated by immunohistochemical studies in this case, further expands the morphologic spectrum of NLPHL...
  15. ncbi request reprint t(8;13)-positive bilineal lymphomas: report of 6 cases
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 32:14-20. 2008
    ..They likely arise from an early hematopoietic cell with potential to differentiate along T-cell and myeloid pathways...
  16. pmc Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma
    Changping Li
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Oncotarget 3:314-26. 2012
    ..These results indicate that Trx-1 plays a key role in cell growth and survival, as well as chemoresistance, and is a potential target to overcome drug resistance in relapsed/refractory DLBCL...
  17. ncbi request reprint Leukemia cutis
    Jeong Hee Cho-Vega
    Department of Pathology, The Methodist Hospital, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Pathol 129:130-42. 2008
    ..We review the literature and recent advances pertaining to LC, with special emphasis on the immunohistochemical assessment and possible mechanisms involved in skin tropism by leukemic cells...
  18. doi request reprint Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features
    Yang O Huh
    Dept of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Am J Clin Pathol 135:686-96. 2011
    ..Our results indicate that t(14;19)(q32;q13) identifies a subset of CLL/SLL with distinctive clinicopathologic and genetic features. Furthermore, t(14;19) may represent an early, possibly primary, genetic event...
  19. pmc Transcriptional regulation of serine/threonine protein kinase (AKT) genes by glioma-associated oncogene homolog 1
    Nitin K Agarwal
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Biol Chem 288:15390-401. 2013
    ..In summary, we demonstrated the existence of a novel cross-talk at the transcriptional level between Hedgehog signaling and AKT with biological significance in DLBCL...
  20. ncbi request reprint Hepatosplenic and other gammadelta T-cell lymphomas
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Pathol 127:869-80. 2007
    ..In contrast with HSTCL, non-HSTCL gammadelta T-cell lymphomas frequently have an activated cytotoxic phenotype and most likely are not a single disease entity...
  21. ncbi request reprint Lymphomas involving the pleura: a clinicopathologic study of 34 cases diagnosed by pleural biopsy
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    Arch Pathol Lab Med 130:1497-502. 2006
    ..Pleural involvement by lymphoma is relatively common. However, there are very few clinicopathologic studies reported in the literature of lymphomas involving the pleura...
  22. pmc Functional inhibition of BCL2 is needed to increase the susceptibility to apoptosis to SMO inhibitors in diffuse large B-cell lymphoma of germinal center subtype
    Kranthi Kunkalla
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Unit 72, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Ann Hematol 92:777-87. 2013
    ..These findings provide a rationale to explore the use of SMO and BCL2 inhibitors as adjuvant therapy for treatment of DLBCL of GC type...
  23. doi request reprint Extranodal NK/T-cell lymphoma, nasal type: a report of 73 cases at MD Anderson Cancer Center
    Shaoying Li
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 37:14-23. 2013
    ..The International Prognostic Index score, anatomic site of disease, and proliferation rate had prognostic value in this patient cohort...
  24. ncbi request reprint Clonal heterogeneity in mycosis fungoides and its relationship to clinical course
    Francisco Vega
    Division of Pathology and Laboratory Medicine, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Blood 100:3369-73. 2002
    ..Demonstration of identical clonal GRs in multiple biopsy specimens at the time of diagnosis may provide prognostic information related to disease progression...
  25. pmc Immunohistochemical markers for tumor associated macrophages and survival in advanced classical Hodgkin's lymphoma
    Beatriz Sánchez-Espiridión
    Department of Pathology, M D Anderson Cancer Center, Houston, TX, USA
    Haematologica 97:1080-4. 2012
    ..In conclusion, individual tumor associated macrophage markers cannot be used to predict outcome before technical standardization and prospective validation in independent series of patients with comparable stages and treatments...
  26. pmc Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma
    Elisa Ramírez
    Molecular Genetic Technology Program, School of Health Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Leuk Res 36:1267-73. 2012
    ..In conclusion, our data support the hypothesis that aberrant activation of Hh signaling in DLBCL mainly results from integration of deregulated oncogenic signaling inputs converging into Hh signaling...
  27. pmc Phenotypic modulation of the stromal reticular network in normal and neoplastic lymph nodes: tissue transglutaminase reveals coordinate regulation of multiple cell types
    Vilmos A Thomazy
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, and the Department of Pathology, University of Texas, Houston Medical School, Houston, Texas, USA
    Am J Pathol 163:165-74. 2003
    ..Using TG as a stromal marker, we have identified differential modulation of the phenotype of the lymph node reticular network that parallels change in the B-cell compartment...
  28. ncbi request reprint Primary cutaneous marginal zone B-cell lymphoma
    Jeong Hee Cho-Vega
    Department of Pathology, The Methodist Hospital, Houston, TX, USA
    Am J Clin Pathol 125:S38-49. 2006
    ..The t(14;18)(q32;q21) and t(11;18)(q21;q21) have been shown to activate the NF-kappaB pathway...
  29. ncbi request reprint Chromosomal translocations involved in non-Hodgkin lymphomas
    Francisco Vega
    Division of Pathology and Laboratory Medicine, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Arch Pathol Lab Med 127:1148-60. 2003
    ..The discovery that recurrent chromosomal translocations are involved in the pathogenesis of non-Hodgkin lymphomas has greatly improved our understanding of these diseases and revolutionized their diagnosis...
  30. doi request reprint Indolent peripheral T-cell lymphoma involving the gastrointestinal tract
    Vasiliki Leventaki
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA, 77030 Department of Pathology, St Jude Children s Research Hospital, Memphis, TN, USA, 38105 Electronic address
    Hum Pathol 45:421-6. 2014
    ..Rare cases of indolent peripheral T-cell lymphoma of the gastrointestinal tract have been previously described and need to be further characterized to avoid the use of aggressive chemotherapy. ..
  31. ncbi request reprint Peripheral T-cell lymphoma arising in the liver
    Mirela Stancu
    Division of Pathology and Laboratory Medicine, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Am J Clin Pathol 118:574-81. 2002
    ..PTCL may rarely arise in the liver. These neoplasms respond to chemotherapy, suggesting that this disease is curable if diagnosed at an early stage...
  32. ncbi request reprint Real-Time t(14;18)(q32;q21) PCR assay combined with high-resolution capillary electrophoresis: a novel and rapid approach that allows accurate quantitation and size determination of bcl-2/JH fusion sequences
    Beatriz Sanchez-Vega
    Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77054, USA
    Mod Pathol 15:448-53. 2002
    ..The JH-NED primer did not interfere with the TaqMan probe fluorescent signal or target detection and allowed subsequent amplicon size determination by semiautomated high-resolution capillary electrophoresis...
  33. ncbi request reprint Molecular genetic methods in the diagnosis of hematologic neoplasms
    Filiz Sen
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Semin Diagn Pathol 19:72-93. 2002
    ..In this review, we focus on chromosomal translocations in hematologic neoplasms and the techniques used for their detection. We also briefly discuss tumor suppressor genes and assessment of clonality in lymphoid neoplasms...
  34. doi request reprint MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis
    Yang O Huh
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Br J Haematol 142:36-44. 2008
    ..In summary, MYC rearrangement, which occurs rarely in CLL patients, is associated with increased prolymphocytes, complex cytogenetic abnormalities, and a poor prognosis...
  35. ncbi request reprint Expression of dicarbonyl/L-xylulose reductase (DCXR) in human skin and melanocytic lesions: morphological studies supporting cell adhesion function of DCXR
    Jeong Hee Cho-Vega
    Department of Pathology, The Methodist Hospital, Houston, TX, USA
    J Cutan Pathol 34:535-42. 2007
    ..It has been proposed that dicarbonyl/L-xylulose reductase (DCXR) is increased in prostate cancer. Also, when compared with normal skin, a virtual northern blot shows increased expression of DCXR in melanomas...
  36. doi request reprint N-terminal PAX8 polyclonal antibody shows cross-reactivity with N-terminal region of PAX5 and is responsible for reports of PAX8 positivity in malignant lymphomas
    Lucas Moretti
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Mod Pathol 25:231-6. 2012
    ..We conclude that positivity for PAX8 reported by others in B-cell lymphomas is likely due to cross-reactivity between the N-terminal regions of PAX8 and PAX5, due to the high sequence homology of these two regions...
  37. ncbi request reprint Precursor T-cell acute lymphoblastic leukemia in adults: age-related immunophenotypic, cytogenetic, and molecular subsets
    Mihaela Onciu
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Am J Clin Pathol 117:252-8. 2002
    ..Within this group, CD1a expression correlated with age 28 to 60 years. These results illustrate considerable age-related heterogeneity in adult T-ALL, which may reflect differences in tumor cell maturation...
  38. ncbi request reprint Extranodal lymphomas of the head and neck
    Francisco Vega
    Department of Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Diagn Pathol 9:340-50. 2005
    ....
  39. doi request reprint Early-stage mycosis fungoides variants: case-based review
    Jeong Hee Cho-Vega
    St Joseph Dermatopathology, Houston, TX 77030, USA
    Ann Diagn Pathol 14:369-85. 2010
    ..In addition, we discuss the role of molecular studies, which are highly sensitive and recently more applicable to routinely processed skin biopsy specimens in the diagnosis of MF...
  40. ncbi request reprint CD4-CD8-"Double-negative" cutaneous T-cell lymphomas share common histologic features and an aggressive clinical course
    Dan Jones
    Division of Pathology and Laboratory Medicine, Department of Lymphoma, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, U S A
    Am J Surg Pathol 26:225-31. 2002
    ..CD4-CD8-"double-negative" CTCL has distinctive histologic features and cytomorphology with a marked propensity for rapid multifocal cutaneous dissemination...
  41. pmc Essential role of TAK1 in regulating mantle cell lymphoma survival
    Daniela Buglio
    Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Blood 120:347-55. 2012
    ..Collectively, our data demonstrate an essential role for TAK1 in regulating critical survival mechanisms in lymphoma and suggest that it may serve as a therapeutic target...
  42. doi request reprint High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearrangements and a poor prognosis
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 61:945-54. 2012
    ..At a haematopathology workshop, experts had suggested the term 'high-grade B cell lymphoma, unclassifiable, with blastoid features', and recommended further studies...
  43. ncbi request reprint Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Res 66:6589-97. 2006
    ..These findings suggest that the mTOR pathway contributes to nucleophosmin-ALK/PI3K/AKT-mediated tumorigenesis and that inhibition of mTOR represents a potential therapeutic strategy in ALK+ ALCL...
  44. ncbi request reprint Epstein-Barr virus-positive B-cell lymphoproliferative disorders arising in immunodeficient patients previously treated with fludarabine for low-grade B-cell neoplasms
    Lynne V Abruzzo
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Surg Pathol 26:630-6. 2002
    ..Most are clonally distinct from the underlying low-grade B-cell neoplasm. A subset of these lesions may regress without systemic therapy...
  45. ncbi request reprint Atypical NK-cell proliferation of the gastrointestinal tract in a patient with antigliadin antibodies but not celiac disease
    Francisco Vega
    Department of Pathology, Baylor College of Medicine, The Methodist Hospital, Houston, TX 77030, USA
    Am J Surg Pathol 30:539-44. 2006
    ..It is as yet unknown whether this process occurs more commonly in patients with gluten sensitivity, or in other settings, and the pathogenesis is as yet undetermined...
  46. ncbi request reprint Chromosomal translocations and their role in the pathogenesis of non-Hodgkin's lymphomas
    Francisco Vega
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Pathology 34:397-409. 2002
    ..This review examines the involved genes in chromosomal translocations and current evidence and postulated mechanisms for their role in the pathogenesis of non-Hodgkin's lymphomas...
  47. doi request reprint Prospective phase II study of rituximab with alternating cycles of hyper-CVAD and high-dose methotrexate with cytarabine for young patients with high-risk diffuse large B-cell lymphoma
    Yasuhiro Oki
    Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Br J Haematol 163:611-20. 2013
    ..In conclusion, R-HCVAD/R-MA is associated with excellent outcome in patients ≤45 years old. However, in patients >45 years old, R-HCVAD/R-MA is associated with unacceptable mortality rates. ..
  48. doi request reprint Extracavitary/solid variant of primary effusion lymphoma
    Yoonjung Kim
    Department of Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Diagn Pathol 16:441-6. 2012
    ..These cases highlight the importance of assessing HHV8 in an anaplastic tumor that arises in a human immunodeficiency virus-positive patient and further contributes to the limited literature currently available for extracavitary PEL...
  49. pmc Cross talk between follicular Th cells and tumor cells in human follicular lymphoma promotes immune evasion in the tumor microenvironment
    Seema Rawal
    Division of Cancer Medicine, Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Immunol 190:6681-93. 2013
    ..Our results provide novel insights into the cross talk among TFH, tumor cells, and Tregs in FL, and offer potential targets for development of therapeutic strategies to overcome immune evasion...