Susana T Valente

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi request reprint Didehydro-Cortistatin A Inhibits HIV-1 Tat Mediated Neuroinflammation and Prevents Potentiation of Cocaine Reward in Tat Transgenic Mice
    Sonia Mediouni
    Department of Infectious Diseases, The Scripps Research Institute, 130 Scripps Way, 3C1, Jupiter, FL 33458, USA
    Curr HIV Res 13:64-79. 2015
  2. pmc HIV-1 mRNA 3' end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8
    Susana T Valente
    Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, HHSC 1310c, 701 West 168th Street, New York, NY 10032, USA
    Mol Cell 36:279-89. 2009
  3. pmc Inhibition of HIV-1 replication by eIF3f
    Susana T Valente
    Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, HHSC 1310c, 701 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 106:4071-8. 2009
  4. pmc An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription
    Guillaume Mousseau
    Department of Infectology, The Scripps Research Institute, Scripps Florida, Jupiter, 33458, USA
    Cell Host Microbe 12:97-108. 2012
  5. ncbi request reprint Inhibition of HIV-1 gene expression by a fragment of hnRNP U
    Susana T Valente
    Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, HHSC 1310c, 701 West 168th Street, New York, New York 10032, USA
    Mol Cell 23:597-605. 2006
  6. pmc Somatic cell genetic analyses to identify HIV-1 host restriction factors
    Susana T Valente
    Department of Biochemistry, Columbia University, Howard Hughes Medical Institute College of Physicians and Surgeons, New York NY, USA
    Methods Mol Biol 485:235-55. 2009
  7. doi request reprint Targeting HIV Transcription: The Quest for a Functional Cure
    Guillaume Mousseau
    Department of Infectious Diseases, The Scripps Research Institute, Jupiter, FL, 33458, USA
    Curr Top Microbiol Immunol 389:121-45. 2015

Collaborators

  • Stephen Goff
  • Phil Baran
  • RĂ©mi Fromentin
  • Guillaume Mousseau
  • Sonia Mediouni
  • Mark A Clementz
  • Jason J Paris
  • Jay P McLaughlin
  • Suzie Thenin-Houssier
  • Joseph Jablonski
  • Nisha Nagarsheth
  • Nicolas Chomont
  • Michael Cameron
  • Jun Shi
  • Wendy N Bakeman

Detail Information

Publications7

  1. ncbi request reprint Didehydro-Cortistatin A Inhibits HIV-1 Tat Mediated Neuroinflammation and Prevents Potentiation of Cocaine Reward in Tat Transgenic Mice
    Sonia Mediouni
    Department of Infectious Diseases, The Scripps Research Institute, 130 Scripps Way, 3C1, Jupiter, FL 33458, USA
    Curr HIV Res 13:64-79. 2015
    ..Our results suggest that adding a Tat inhibitor, such as dCA, to current antiretroviral therapy may reduce HIV-1-related neuropathogenesis. ..
  2. pmc HIV-1 mRNA 3' end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8
    Susana T Valente
    Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, HHSC 1310c, 701 West 168th Street, New York, NY 10032, USA
    Mol Cell 36:279-89. 2009
    ..eIF3f affects HIV-1 3' end processing by modulating the sequence-specific recognition of the HIV-1 pre-mRNA by 9G8...
  3. pmc Inhibition of HIV-1 replication by eIF3f
    Susana T Valente
    Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, HHSC 1310c, 701 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 106:4071-8. 2009
    ..Our results suggest a role of eIF3f in mRNA maturation and that it can specifically interfere with the 3' end processing of HIV-1 mRNAs...
  4. pmc An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription
    Guillaume Mousseau
    Department of Infectology, The Scripps Research Institute, Scripps Florida, Jupiter, 33458, USA
    Cell Host Microbe 12:97-108. 2012
    ..Thus, dCA defines a unique class of anti-HIV drugs that may inhibit viral production from stable reservoirs and reduce residual viremia during HAART...
  5. ncbi request reprint Inhibition of HIV-1 gene expression by a fragment of hnRNP U
    Susana T Valente
    Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, HHSC 1310c, 701 West 168th Street, New York, New York 10032, USA
    Mol Cell 23:597-605. 2006
    ..The results suggest that HIV-1 requires machinery for the nuclear export of viral mRNAs that can be specifically blocked by an interfering gene...
  6. pmc Somatic cell genetic analyses to identify HIV-1 host restriction factors
    Susana T Valente
    Department of Biochemistry, Columbia University, Howard Hughes Medical Institute College of Physicians and Surgeons, New York NY, USA
    Methods Mol Biol 485:235-55. 2009
    ..Here we report the strategy and techniques to prepare a library and isolate HIV antiviral genes, using the identification of N-86-HnRNPU as an example...
  7. doi request reprint Targeting HIV Transcription: The Quest for a Functional Cure
    Guillaume Mousseau
    Department of Infectious Diseases, The Scripps Research Institute, Jupiter, FL, 33458, USA
    Curr Top Microbiol Immunol 389:121-45. 2015
    ..Finally, we discuss the impact of extracellular Tat in HIV-associated neurocognitive disorders and cancers. ..