Glenn R Valdez

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi request reprint Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide
    Glenn R Valdez
    Department of Neuropharmacology, CVN7, The Scripps Research Institute, La Jolla, CA 92037, USA
    Brain Res 943:142-50. 2002
  2. ncbi request reprint Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor
    Glenn R Valdez
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 26:1494-501. 2002
  3. ncbi request reprint Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence
    Glenn R Valdez
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Alcohol 29:55-60. 2003
  4. ncbi request reprint Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist
    Glenn R Valdez
    Department of Neuropharmacology, CVN7, Scripps Research Institute, 10550 North Torrey Pines Rd, La Jolla, CA 92037, USA
    Brain Res 980:206-12. 2003
  5. ncbi request reprint Human urocortin 2, a corticotropin-releasing factor (CRF)2 agonist, and ovine CRF, a CRF1 agonist, differentially alter feeding and motor activity
    Eric P Zorrilla
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Pharmacol Exp Ther 310:1027-34. 2004
  6. ncbi request reprint Measuring meals: structure of prandial food and water intake of rats
    Eric P Zorrilla
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1450-67. 2005
  7. ncbi request reprint Reduction of anxiety after restricted feeding in the rat: implication for eating disorders
    Koki Inoue
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
    Biol Psychiatry 55:1075-81. 2004
  8. ncbi request reprint Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the rat
    Koki Inoue
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
    J Pharmacol Exp Ther 305:385-93. 2003
  9. ncbi request reprint Increased anxiety-like behavior and ethanol self-administration in dependent rats: reversal via corticotropin-releasing factor-2 receptor activation
    Glenn R Valdez
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
    Alcohol Clin Exp Res 28:865-72. 2004
  10. ncbi request reprint Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat
    Eric P Zorrilla
    Department of Neuropharmacology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Psychopharmacology (Berl) 177:324-35. 2005

Detail Information

Publications15

  1. ncbi request reprint Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide
    Glenn R Valdez
    Department of Neuropharmacology, CVN7, The Scripps Research Institute, La Jolla, CA 92037, USA
    Brain Res 943:142-50. 2002
    ..Thus, hUcn II exhibits mild motor suppressive effects and delayed anxiolytic-like effects, suggesting a time-dependent role for hUcn II in the regulation of stress-related behavior...
  2. ncbi request reprint Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor
    Glenn R Valdez
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 26:1494-501. 2002
    ..The objective of the present study was to investigate the role of CRF in the regulation of ethanol self-administration and to examine the behavioral stress response during acute withdrawal and protracted abstinence...
  3. ncbi request reprint Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence
    Glenn R Valdez
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Alcohol 29:55-60. 2003
    ..Results of the current experiment demonstrated that continuous exposure to ethanol over a 3-week period leads to an increased behavioral responsiveness to stress, which seems to be regulated by CRF...
  4. ncbi request reprint Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist
    Glenn R Valdez
    Department of Neuropharmacology, CVN7, Scripps Research Institute, 10550 North Torrey Pines Rd, La Jolla, CA 92037, USA
    Brain Res 980:206-12. 2003
    ....
  5. ncbi request reprint Human urocortin 2, a corticotropin-releasing factor (CRF)2 agonist, and ovine CRF, a CRF1 agonist, differentially alter feeding and motor activity
    Eric P Zorrilla
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Pharmacol Exp Ther 310:1027-34. 2004
    ..The results suggest the existence of distinct forms of CRF1- and CRF2-mediated anorexia...
  6. ncbi request reprint Measuring meals: structure of prandial food and water intake of rats
    Eric P Zorrilla
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1450-67. 2005
    ..Thus log-survivorship analysis is not appropriate for identifying meal breakpoints, and the consideration of drinking in meal definitions can provide a better estimate of meal structure...
  7. ncbi request reprint Reduction of anxiety after restricted feeding in the rat: implication for eating disorders
    Koki Inoue
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
    Biol Psychiatry 55:1075-81. 2004
    ..Eating-disorder patients exhibit not only abnormal eating attitudes but also pathologic anxiety-like behaviors. The specific nature of the relationship between dieting and anxiety-like behavior is unknown...
  8. ncbi request reprint Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the rat
    Koki Inoue
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
    J Pharmacol Exp Ther 305:385-93. 2003
    ..hUcn II is a promising neuropeptide for investigating the role of the CRF(2) receptor in ingestive behavior...
  9. ncbi request reprint Increased anxiety-like behavior and ethanol self-administration in dependent rats: reversal via corticotropin-releasing factor-2 receptor activation
    Glenn R Valdez
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
    Alcohol Clin Exp Res 28:865-72. 2004
    ....
  10. ncbi request reprint Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat
    Eric P Zorrilla
    Department of Neuropharmacology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Psychopharmacology (Berl) 177:324-35. 2005
    ..Many attempts to understand ingestion have sought to clarify the control of meals. Little is known about the effects of the anorexogenic hormone leptin on meal patterning...
  11. ncbi request reprint Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat
    Eric P Zorrilla
    Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Brain Res 952:188-99. 2002
    ....
  12. ncbi request reprint Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: implications for the development of alcoholism
    Glenn R Valdez
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Pharmacol Biochem Behav 79:671-89. 2004
    ....
  13. ncbi request reprint Development of CRF1 receptor antagonists as antidepressants and anxiolytics: progress to date
    Glenn R Valdez
    Department of Psychology, Grand Valley State University, Allendale, MI 49401, USA
    CNS Drugs 20:887-96. 2006
    ..Further development of these compounds is warranted...
  14. ncbi request reprint Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms
    Glenn R Valdez
    Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA
    J Pharmacol Exp Ther 323:525-33. 2007
    ..The results point to interactions between a subpopulation of kappa opioid receptors and central corticotropin-releasing factor and noradrenergic stress systems in the reinstatement of cocaine seeking induced by kappa agonists...
  15. pmc Stress enhancement of craving during sobriety: a risk for relapse
    George R Breese
    Bowles Center for Alcohol Studies, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Alcohol Clin Exp Res 29:185-95. 2005
    ..Collectively, the presentations provided convincing support for an involvement of stress in the cause of relapse and continuing alcohol abuse and suggested novel pharmacological approaches for treating relapse induced by stress...