Cecilia G Unson

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi The role of salt bridge formation in glucagon: an experimental and theoretical study of glucagon analogs and peptide fragments of glucagon
    Anne Marie Sapse
    John Jay College and Graduate School, City University of New York, New York, NY 10019, USA
    Mol Med 8:251-62. 2002
  2. ncbi Molecular determinants of glucagon receptor signaling
    Cecilia G Unson
    The Rockefeller University, 1230 York Avenue, Box 294, New York, NY 10021, USA
    Biopolymers 66:218-35. 2002
  3. ncbi Roles of specific extracellular domains of the glucagon receptor in ligand binding and signaling
    Cecilia G Unson
    Howard Hughes Medical Institute, Laboratory of Molecular Biology and Biochemistry, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Biochemistry 41:11795-803. 2002
  4. ncbi Expression of glucagon receptors in tetracycline-inducible HEK293S GnT1- stable cell lines: an approach toward purification of receptor protein for structural studies
    Cecilia G Unson
    Rockefeller University, New York, NY 10065, USA
    Biopolymers 90:287-96. 2008
  5. ncbi Merrifield laboratory: last member standing
    Cecilia G Unson
    Rockefeller University, New York, NY 10065, USA
    Biopolymers 90:243-4. 2008
  6. ncbi Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver
    Clemence Merlen
    Institut National de la Santé et de la Recherche Médicale Unité 756, Faculte de Pharmacie Paris XI, 92296 Chatenay Malabry, France
    FEBS Lett 580:5697-704. 2006
  7. ncbi High-fat diet-induced hepatic steatosis reduces glucagon receptor content in rat hepatocytes: potential interaction with acute exercise
    Alexandre Charbonneau
    Department of Kinésiologie, Universite de Montreal, Montreal, Quebec, Canada
    J Physiol 579:255-67. 2007
  8. ncbi Glucagon-expressing neurons within the retina regulate the proliferation of neural progenitors in the circumferential marginal zone of the avian eye
    Andy J Fischer
    Department of Neuroscience, The Ohio State University, Columbus, Ohio 43210 1239, USA
    J Neurosci 25:10157-66. 2005

Collaborators

Detail Information

Publications8

  1. ncbi The role of salt bridge formation in glucagon: an experimental and theoretical study of glucagon analogs and peptide fragments of glucagon
    Anne Marie Sapse
    John Jay College and Graduate School, City University of New York, New York, NY 10019, USA
    Mol Med 8:251-62. 2002
    ..The presence of salt bridges between some residues of glucagons (such as aspartic acid) and others (such as lysine) might influence both the binding to the receptor and the activity...
  2. ncbi Molecular determinants of glucagon receptor signaling
    Cecilia G Unson
    The Rockefeller University, 1230 York Avenue, Box 294, New York, NY 10021, USA
    Biopolymers 66:218-35. 2002
    ..Information about the glucagon receptor is presented within the context of what is known about other members of the family B GPCRs...
  3. ncbi Roles of specific extracellular domains of the glucagon receptor in ligand binding and signaling
    Cecilia G Unson
    Howard Hughes Medical Institute, Laboratory of Molecular Biology and Biochemistry, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Biochemistry 41:11795-803. 2002
    ....
  4. ncbi Expression of glucagon receptors in tetracycline-inducible HEK293S GnT1- stable cell lines: an approach toward purification of receptor protein for structural studies
    Cecilia G Unson
    Rockefeller University, New York, NY 10065, USA
    Biopolymers 90:287-96. 2008
    ..This report describes a feasible approach for the preparation of human GR and other family B GPCRs in the quantities required for structural studies...
  5. ncbi Merrifield laboratory: last member standing
    Cecilia G Unson
    Rockefeller University, New York, NY 10065, USA
    Biopolymers 90:243-4. 2008
  6. ncbi Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver
    Clemence Merlen
    Institut National de la Santé et de la Recherche Médicale Unité 756, Faculte de Pharmacie Paris XI, 92296 Chatenay Malabry, France
    FEBS Lett 580:5697-704. 2006
    ....
  7. ncbi High-fat diet-induced hepatic steatosis reduces glucagon receptor content in rat hepatocytes: potential interaction with acute exercise
    Alexandre Charbonneau
    Department of Kinésiologie, Universite de Montreal, Montreal, Quebec, Canada
    J Physiol 579:255-67. 2007
    ..Furthermore, the GR desensitization observed in our in vivo model of HF diet-induced hepatic steatosis and in EX individuals may be regulated by PKC-alpha...
  8. ncbi Glucagon-expressing neurons within the retina regulate the proliferation of neural progenitors in the circumferential marginal zone of the avian eye
    Andy J Fischer
    Department of Neuroscience, The Ohio State University, Columbus, Ohio 43210 1239, USA
    J Neurosci 25:10157-66. 2005
    ..We propose that glucagon/GLP1 released from LGENs acts in opposition to insulin (or insulin-like growth factor) to regulate precisely the proliferation of retinal progenitors in the CMZ...