Research Topics
Species | Anne S TsaoSummaryAffiliation: The University of Texas Country: USA Publications
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Publications
Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trialAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
J Thorac Oncol 7:1645-52. 2012..Here we report outcomes (survival and toxicity) of elderly patients on the Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE) trial...
Phase II trials of imatinib mesylate and docetaxel in patients with metastatic non-small cell lung cancer and head and neck squamous cell carcinomaAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Thorac Oncol 6:2104-11. 2011..Baseline tumor specimens, serum, and perfusion computed tomography (CT) scans were obtained for supportive evaluation...
Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasionAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 432, Houston, TX 77030, USA
Mol Cancer Ther 6:1962-72. 2007..02). Activated c-Src may play a role in survival, metastasis, and invasion of MPM, and targeting c-Src may be an important therapeutic strategy...
A practical guide of the Southwest Oncology Group to measure malignant pleural mesothelioma tumors by RECIST and modified RECIST criteriaAnne S Tsao
Department of Thoracic and Head and Neck Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Thorac Oncol 6:598-601. 2011..With this consistency, we may be able to better estimate the prognosis and response to therapy. With greater utilization, we will be able to better understand the biology of MPM...
Neoadjuvant and intrapleural therapies for malignant pleural mesotheliomaAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Clin Lung Cancer 10:36-41. 2009..The following review discusses the latest results in neoadjuvant and intrapleural therapies in malignant pleural mesothelioma...
Malignant pleural mesotheliomaAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 432, Houston, TX 77030, USA
J Clin Oncol 27:2081-90. 2009..In addition, there are controversial issues, such as the role of extrapleural pneumonectomy, adjuvant radiotherapy, and use of intensity-modulated radiotherapy versus hemithoracic therapy that will also be addressed in this manuscript...
Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR-β) is associated with PDGFRB gene copy number gain in sarcomatoid non-small-cell lung cancerAnne S Tsao
Department of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Clin Lung Cancer 12:369-74. 2011..Further studies are warranted to determine whether PDGFR-b is a feasible therapeutic target in this population...
Smoking affects treatment outcome in patients with advanced nonsmall cell lung cancerAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 106:2428-36. 2006..The purpose of the current study was to determine whether smoking during chemotherapy or chemoradiation therapy for nonsmall cell lung cancer (NSCLC) affects treatment outcome...
The role of consolidation therapy for stage III non-small cell lung cancer with persistent N2 disease after induction chemotherapyArya Amini
Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Ann Thorac Surg 94:914-20. 2012..We assessed the role of consolidative therapies (postoperative radiation therapy and chemotherapy) for such patients...
Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung cancerAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
J Thorac Oncol 1:231-9. 2006..The authors sought to define clinicopathologic features associated with mutations of the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer (NSCLC)...
Phase I/II study of docetaxel, cisplatin, and concomitant boost radiation for locally advanced squamous cell cancer of the head and neckAnne S Tsao
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 24:4163-9. 2006..Phase III trials are needed to assess the contribution of concomitant boost fractionation to chemoradiotherapy...
Asian ethnicity as a predictor of response in patients with non-small-cell lung cancer treated with gefitinib on an expanded access programSheeba K Thomas
Department of Lymphoma/Myeloma, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
Clin Lung Cancer 7:326-31. 2006..CONCLUSION: For the first time, in a multivariate analysis, we observed a positive relationship between East Asian origin and response to gefitinib. These findings might help determine which patients will likely benefit from gefitinib...
Chemoprevention of cancerAnne S Tsao
Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA
CA Cancer J Clin 54:150-80. 2004..Future directions in the field of chemoprevention will be proposed that are based on recently acquired mechanistic insight into carcinogenesis...
Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesionsAnne S Tsao
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer Prev Res (Phila) 2:931-41. 2009..Higher doses of GTE may improve short-term (12-week) OPL outcome. The present results support longer-term clinical testing of GTE for oral cancer prevention...
Extended surgical staging for potentially resectable malignant pleural mesotheliomaDavid C Rice
Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Ann Thorac Surg 80:1988-92; discussion 1992-3. 2005..We evaluated the role of extended surgical staging procedures, which generally includes a combination of laparoscopy, peritoneal lavage, and mediastinoscopy, to more precisely stage patients with MPM...
Meta-analysis of the impact of human papillomavirus (HPV) on cancer risk and overall survival in head and neck squamous cell carcinomas (HNSCC)Farshid Dayyani
Department of Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Head Neck Oncol 2:15. 2010..HPV is important in a subset of HNSCC. Our meta-analysis determined the clinical characteristics of HPV-related HNSCC...
C-kit receptor expression in acute leukemias-association with patient and disease characteristics and with outcomeAnne S Tsao
MD Anderson Cancer Center, University of Texas, 1515 Holcombe Boulevard, P.O. Box 428 Houston, TX 77030, USA
Leuk Res 28:373-8. 2004..However, after accounting for these covariates, multivariate analysis indicates that higher c-kit expression predicts higher CR rates, although there was no effect on DFS in CR...
Imatinib mesylate causes hypopigmentation in the skinAnne S Tsao
Medical Oncology Fellowship Program, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 98:2483-7. 2003..Once phosphorylated, Mi transactivates the tyrosine pigmentation gene promoter and affects pigment production...
Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studiesAnne S Tsao
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA
Cancer Epidemiol Biomarkers Prev 12:660-4. 2003..Given its role as a mediator of malignant transformation, p-AKT should be investigated as a potential target in future lung cancer prevention studies...
Nonsmall-cell lung cancer: chemoprevention studiesDaniel D Karp
MD Anderson Cancer Center, Houston, TX 77030 4009, USA
Semin Thorac Cardiovasc Surg 15:405-20. 2003....
Patterns of failure, toxicity, and survival after extrapleural pneumonectomy and hemithoracic intensity-modulated radiation therapy for malignant pleural mesotheliomaDaniel R Gomez
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77054, USA
J Thorac Oncol 8:238-45. 2013....
Phase I evaluation of docetaxel and topotecan for patients with advanced solid tumorsAnne S Tsao
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 100:2240-5. 2004..CONCLUSIONS: This trial demonstrated that a regimen of docetaxel and topotecan with G-CSF support was generally well tolerated and had promising activity in patients with nasopharyngeal and SCLC...
STI-571 in chronic myelogenous leukaemiaAnne S Tsao
Department of Bioimmunotherapy, M D Anderson Cancer Center, Houston, TX, USA
Br J Haematol 119:15-24. 2002
Surgery: Future directions in multimodality therapy for NSCLCAnne S Tsao
Department of Thoracic and Head and Neck Medical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Nat Rev Clin Oncol 7:10-2. 2010..Albain and colleagues recently demonstrated that trimodality therapy with lobectomy had clinical benefit for patients with pathologic nodal N2 stage III nSclc. we discuss the trial and its implications for future lung cancer therapy...
