Tambet Teesalu

Summary

Affiliation: The Burnham Institute
Country: USA

Publications

  1. pmc C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    Tambet Teesalu
    Vascular Mapping Center, The Burnham Institute for Medical Research at University of California, Santa Barbara, CA 93106 9610, USA
    Proc Natl Acad Sci U S A 106:16157-62. 2009
  2. doi request reprint Mapping of vascular ZIP codes by phage display
    Tambet Teesalu
    Center for Nanomedicine, Sanford Burnham Medical Research Institute at UCSB, Santa Barbara, California, USA
    Methods Enzymol 503:35-56. 2012
  3. pmc Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
    Kazuki N Sugahara
    Vascular Mapping Laboratory, Center for Nanomedicine, Sanford Burnham Medical Research Institute at University of California at Santa Barbara, Biology II Building, University of California, Santa Barbara, CA 93106 9610, USA
    Science 328:1031-5. 2010
  4. pmc Application of a proapoptotic peptide to intratumorally spreading cancer therapy
    Renwei Chen
    Center for Nanomedicine, Sanford Burnham Medical Research Institute, University of California, Santa Barbara, CA, USA
    Cancer Res 73:1352-61. 2013
  5. pmc Tissue-penetrating delivery of compounds and nanoparticles into tumors
    Kazuki N Sugahara
    Vascular Mapping Center, Burnham Institute for Medical Research at UCSB, Biology II Building, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
    Cancer Cell 16:510-20. 2009
  6. pmc Selection of phage-displayed peptides on live adherent cells in microfluidic channels
    Jinpeng Wang
    Department of Mechanical Engineering, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 108:6909-14. 2011

Collaborators

  • Erkki Ruoslahti
  • Yi Xiao
  • Douglas Hanahan
  • Kazuki N Sugahara
  • Renwei Chen
  • Jinpeng Wang
  • Lilach Agemy
  • Priya Prakash Karmali
  • Venkata Ramana Kotamraju
  • Gary B Braun
  • Xiuquan Luo
  • Qiang Gong
  • Yanli Liu
  • Seung Soo Oh
  • Jonathan D Adams
  • Minseon Cho
  • Venkata Ramana Kotamrajua
  • Brian S Ferguson
  • Andrew T Csordas
  • H Tom Soh
  • Daniel R Greenwald
  • Olivier M Girard
  • Robert F Mattrey

Detail Information

Publications6

  1. pmc C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    Tambet Teesalu
    Vascular Mapping Center, The Burnham Institute for Medical Research at University of California, Santa Barbara, CA 93106 9610, USA
    Proc Natl Acad Sci U S A 106:16157-62. 2009
    ..The peptides were able to take payloads up to the nanoparticle size scale deep into extravascular tissue. Our observations have implications in drug delivery and penetration of tissue barriers and tumors...
  2. doi request reprint Mapping of vascular ZIP codes by phage display
    Tambet Teesalu
    Center for Nanomedicine, Sanford Burnham Medical Research Institute at UCSB, Santa Barbara, California, USA
    Methods Enzymol 503:35-56. 2012
    ..We focus on T7 coliphage platform that our lab prefers to use due to its versatility, physical resemblance of phage particles to clinical nanoparticles, and ease of manipulation...
  3. pmc Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
    Kazuki N Sugahara
    Vascular Mapping Laboratory, Center for Nanomedicine, Sanford Burnham Medical Research Institute at University of California at Santa Barbara, Biology II Building, University of California, Santa Barbara, CA 93106 9610, USA
    Science 328:1031-5. 2010
    ..Thus, coadministration of iRGD may be a valuable way to enhance the efficacy of anticancer drugs while reducing their side effects, a primary goal of cancer therapy research...
  4. pmc Application of a proapoptotic peptide to intratumorally spreading cancer therapy
    Renwei Chen
    Center for Nanomedicine, Sanford Burnham Medical Research Institute, University of California, Santa Barbara, CA, USA
    Cancer Res 73:1352-61. 2013
    ..Using iRGD to facilitate the spreading of a therapeutic agent throughout the tumor mass may be a useful adjunct to local therapy for tumors that are surgically inoperable or difficult to treat systemically...
  5. pmc Tissue-penetrating delivery of compounds and nanoparticles into tumors
    Kazuki N Sugahara
    Vascular Mapping Center, Burnham Institute for Medical Research at UCSB, Biology II Building, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
    Cancer Cell 16:510-20. 2009
    ..Conjugation to iRGD significantly improved the sensitivity of tumor-imaging agents and enhanced the activity of an antitumor drug...
  6. pmc Selection of phage-displayed peptides on live adherent cells in microfluidic channels
    Jinpeng Wang
    Department of Mechanical Engineering, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 108:6909-14. 2011
    ..As such microfluidic systems can be used with a wide range of biocombinatorial libraries and tissue types, we believe that our method represents an effective approach toward efficient biomarker discovery from patient samples...