Tambet Teesalu

Summary

Affiliation: The Burnham Institute
Country: USA

Publications

  1. ncbi C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    Tambet Teesalu
    Vascular Mapping Center, The Burnham Institute for Medical Research at University of California, Santa Barbara, CA 93106 9610, USA
    Proc Natl Acad Sci U S A 106:16157-62. 2009
  2. ncbi Mapping of vascular ZIP codes by phage display
    Tambet Teesalu
    Center for Nanomedicine, Sanford Burnham Medical Research Institute at UCSB, Santa Barbara, California, USA
    Methods Enzymol 503:35-56. 2012
  3. ncbi Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
    Kazuki N Sugahara
    Vascular Mapping Laboratory, Center for Nanomedicine, Sanford Burnham Medical Research Institute at University of California at Santa Barbara, Biology II Building, University of California, Santa Barbara, CA 93106 9610, USA
    Science 328:1031-5. 2010
  4. ncbi Tissue-penetrating delivery of compounds and nanoparticles into tumors
    Kazuki N Sugahara
    Vascular Mapping Center, Burnham Institute for Medical Research at UCSB, Biology II Building, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
    Cancer Cell 16:510-20. 2009
  5. ncbi Application of a proapoptotic peptide to intratumorally spreading cancer therapy
    Renwei Chen
    Center for Nanomedicine, Sanford Burnham Medical Research Institute, University of California, Santa Barbara, CA, USA
    Cancer Res 73:1352-61. 2013
  6. ncbi Selection of phage-displayed peptides on live adherent cells in microfluidic channels
    Jinpeng Wang
    Department of Mechanical Engineering, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 108:6909-14. 2011

Collaborators

  • Erkki Ruoslahti
  • Kazuki N Sugahara
  • Renwei Chen
  • Jinpeng Wang
  • Venkata Ramana Kotamraju
  • Lilach Agemy
  • Priya Prakash Karmali
  • Gary B Braun
  • Xiuquan Luo
  • Jonathan D Adams
  • Yi Xiao
  • Qiang Gong
  • H Tom Soh
  • Andrew T Csordas
  • Seung Soo Oh
  • Venkata Ramana Kotamrajua
  • Brian S Ferguson
  • Yanli Liu
  • Minseon Cho
  • Daniel R Greenwald
  • Douglas Hanahan
  • Olivier M Girard
  • Robert F Mattrey

Detail Information

Publications6

  1. ncbi C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    Tambet Teesalu
    Vascular Mapping Center, The Burnham Institute for Medical Research at University of California, Santa Barbara, CA 93106 9610, USA
    Proc Natl Acad Sci U S A 106:16157-62. 2009
    ..The peptides were able to take payloads up to the nanoparticle size scale deep into extravascular tissue. Our observations have implications in drug delivery and penetration of tissue barriers and tumors...
  2. ncbi Mapping of vascular ZIP codes by phage display
    Tambet Teesalu
    Center for Nanomedicine, Sanford Burnham Medical Research Institute at UCSB, Santa Barbara, California, USA
    Methods Enzymol 503:35-56. 2012
    ..We focus on T7 coliphage platform that our lab prefers to use due to its versatility, physical resemblance of phage particles to clinical nanoparticles, and ease of manipulation...
  3. ncbi Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
    Kazuki N Sugahara
    Vascular Mapping Laboratory, Center for Nanomedicine, Sanford Burnham Medical Research Institute at University of California at Santa Barbara, Biology II Building, University of California, Santa Barbara, CA 93106 9610, USA
    Science 328:1031-5. 2010
    ..Thus, coadministration of iRGD may be a valuable way to enhance the efficacy of anticancer drugs while reducing their side effects, a primary goal of cancer therapy research...
  4. ncbi Tissue-penetrating delivery of compounds and nanoparticles into tumors
    Kazuki N Sugahara
    Vascular Mapping Center, Burnham Institute for Medical Research at UCSB, Biology II Building, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
    Cancer Cell 16:510-20. 2009
    ..Conjugation to iRGD significantly improved the sensitivity of tumor-imaging agents and enhanced the activity of an antitumor drug...
  5. ncbi Application of a proapoptotic peptide to intratumorally spreading cancer therapy
    Renwei Chen
    Center for Nanomedicine, Sanford Burnham Medical Research Institute, University of California, Santa Barbara, CA, USA
    Cancer Res 73:1352-61. 2013
    ..Using iRGD to facilitate the spreading of a therapeutic agent throughout the tumor mass may be a useful adjunct to local therapy for tumors that are surgically inoperable or difficult to treat systemically...
  6. ncbi Selection of phage-displayed peptides on live adherent cells in microfluidic channels
    Jinpeng Wang
    Department of Mechanical Engineering, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 108:6909-14. 2011
    ..As such microfluidic systems can be used with a wide range of biocombinatorial libraries and tissue types, we believe that our method represents an effective approach toward efficient biomarker discovery from patient samples...