Sean D Taverna

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena
    Sean D Taverna
    Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA
    Cell 110:701-11. 2002
  2. ncbi How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
    Sean D Taverna
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA
    Nat Struct Mol Biol 14:1025-40. 2007
  3. pmc RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena
    Yifan Liu
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA
    Genes Dev 21:1530-45. 2007
  4. pmc Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini
    Sean D Taverna
    Laboratory of Chromatin Biology, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:2086-91. 2007
  5. ncbi Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
    Sean D Taverna
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA
    Mol Cell 24:785-96. 2006
  6. pmc Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
    Katrina B Morshead
    Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 100:11577-82. 2003
  7. ncbi The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved
    Cynthia M Barber
    Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA
    Chromosoma 112:360-71. 2004
  8. pmc Saccharomyces cerevisiae Yta7 regulates histone gene expression
    Angeline Gradolatto
    Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Genetics 179:291-304. 2008

Collaborators

Detail Information

Publications8

  1. ncbi Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena
    Sean D Taverna
    Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA
    Cell 110:701-11. 2002
    ..These results extend the range of H3(Lys9)Me involvement in chromatin activities outside transcriptional regulation and also strengthen the link between heterochromatin formation and programmed DNA elimination...
  2. ncbi How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
    Sean D Taverna
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA
    Nat Struct Mol Biol 14:1025-40. 2007
    ..Changes in these interactions may have far-reaching implications for human biology and disease, notably cancer...
  3. pmc RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena
    Yifan Liu
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA
    Genes Dev 21:1530-45. 2007
    ..These studies provide a framework for an RNAi-dependent, Polycomb group protein-mediated heterochromatin formation pathway in Tetrahymena and underscore the connection between the two highly conserved machineries in eukaryotes...
  4. pmc Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini
    Sean D Taverna
    Laboratory of Chromatin Biology, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:2086-91. 2007
    ..This methodology is applicable to other histones and larger polypeptides and will likely be a valuable tool in understanding the roles of combinatorial patterns of PTMs...
  5. ncbi Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
    Sean D Taverna
    Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10021, USA
    Mol Cell 24:785-96. 2006
    ..Our data support a general mechanism of transcriptional control through which histone acetylation upstream of gene activation is promoted partially through availability of H3K4me3, "read" by binding modules in select subunits...
  6. pmc Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
    Katrina B Morshead
    Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 100:11577-82. 2003
    ..The specific patterns of modification imply that the regulation of V(D)J recombination involves recruitment of specific methyltransferases in a localized manner...
  7. ncbi The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved
    Cynthia M Barber
    Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA
    Chromosoma 112:360-71. 2004
    ..The evolutionarily conserved phosphorylation of H4/H2A during the cell cycle suggests that they may have a dual purpose in chromatin condensation during mitosis and histone deposition during S-phase...
  8. pmc Saccharomyces cerevisiae Yta7 regulates histone gene expression
    Angeline Gradolatto
    Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Genetics 179:291-304. 2008
    ..Our work suggests a mechanism in which Yta7 is localized to chromatin to establish regions of transcriptional silencing, and that one facet of this cellular mechanism is to modulate transcription of histone genes...