Stephen G Swisher

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc A Phase II study of a paclitaxel-based chemoradiation regimen with selective surgical salvage for resectable locoregionally advanced esophageal cancer: initial reporting of RTOG 0246
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Int J Radiat Oncol Biol Phys 82:1967-72. 2012
  2. pmc Clinical outcome and predictors of survival and pneumonitis after stereotactic ablative radiotherapy for stage I non-small cell lung cancer
    Joe Y Chang
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    Radiat Oncol 7:152. 2012
  3. ncbi request reprint Effect of operative volume on morbidity, mortality, and hospital use after esophagectomy for cancer
    S G Swisher
    Departments of Thoracic and Cardiovascular Surgery, Medical Informatics, Gastrointestinal Oncology, and Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    J Thorac Cardiovasc Surg 119:1126-32. 2000
  4. pmc Proposed revision of the esophageal cancer staging system to accommodate pathologic response (pP) following preoperative chemoradiation (CRT)
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg 241:810-7; discussion 817-20. 2005
  5. ncbi request reprint 2-Fluoro-2-deoxy-D-glucose positron emission tomography imaging is predictive of pathologic response and survival after preoperative chemoradiation in patients with esophageal carcinoma
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:1776-85. 2004
  6. doi request reprint Improved long-term outcome with chemoradiotherapy strategies in esophageal cancer
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 90:892-8; discussion 898-9. 2010
  7. ncbi request reprint The supercharged microvascular jejunal interposition
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Thorac Cardiovasc Surg 19:56-65. 2007
  8. ncbi request reprint Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer
    Stephen G Swisher
    Department of Thoracic Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Ann Thorac Surg 78:1152-60; discussion 1152-60. 2004
  9. ncbi request reprint Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 9:93-101. 2003
  10. ncbi request reprint Clinical update of Ad-p53 gene therapy for lung cancer
    Stephen G Swisher
    University of Texas, M D Anderson Cancer Center, Department of Thoracic and Cardiovascular Surgery, Box 445, Houston, TX 77030, USA
    Surg Oncol Clin N Am 11:521-35. 2002

Detail Information

Publications110 found, 100 shown here

  1. pmc A Phase II study of a paclitaxel-based chemoradiation regimen with selective surgical salvage for resectable locoregionally advanced esophageal cancer: initial reporting of RTOG 0246
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Int J Radiat Oncol Biol Phys 82:1967-72. 2012
    ..The strategy of definitive chemoradiation with selective surgical salvage in locoregionally advanced esophageal cancer was evaluated in a Phase II trial in Radiation Therapy Oncology Group (RTOG)-affiliated sites...
  2. pmc Clinical outcome and predictors of survival and pneumonitis after stereotactic ablative radiotherapy for stage I non-small cell lung cancer
    Joe Y Chang
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    Radiat Oncol 7:152. 2012
    ..However, factors that may predict toxicity or survival are largely unknown. We sought here to identify predictors of survival and pneumonitis after SABR for NSCLC in a relatively large single-institution series...
  3. ncbi request reprint Effect of operative volume on morbidity, mortality, and hospital use after esophagectomy for cancer
    S G Swisher
    Departments of Thoracic and Cardiovascular Surgery, Medical Informatics, Gastrointestinal Oncology, and Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    J Thorac Cardiovasc Surg 119:1126-32. 2000
    ..We sought to evaluate the effect of operative volume, hospital size, and cancer specialization on morbidity, mortality, and hospital use after esophagectomy for cancer...
  4. pmc Proposed revision of the esophageal cancer staging system to accommodate pathologic response (pP) following preoperative chemoradiation (CRT)
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg 241:810-7; discussion 817-20. 2005
    ..To determine the impact of pathologic response following preoperative chemoradiation (CRT) on the AJCC esophageal cancer staging system...
  5. ncbi request reprint 2-Fluoro-2-deoxy-D-glucose positron emission tomography imaging is predictive of pathologic response and survival after preoperative chemoradiation in patients with esophageal carcinoma
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:1776-85. 2004
    ..Preliminary reports suggest that FDG-PET may be predictive of the response of esophageal carcinoma patients to preoperative CRT...
  6. doi request reprint Improved long-term outcome with chemoradiotherapy strategies in esophageal cancer
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 90:892-8; discussion 898-9. 2010
    ..We therefore reviewed sequential phase II/III trials performed at a single institution to assess the impact of preoperative chemotherapy versus preoperative C/RT strategies...
  7. ncbi request reprint The supercharged microvascular jejunal interposition
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Thorac Cardiovasc Surg 19:56-65. 2007
    ....
  8. ncbi request reprint Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer
    Stephen G Swisher
    Department of Thoracic Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Ann Thorac Surg 78:1152-60; discussion 1152-60. 2004
    ....
  9. ncbi request reprint Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 9:93-101. 2003
    ..We designed a prospective single arm Phase II study to evaluate the feasibility and mechanisms of apoptosis induction after Ad-p53 (INGN 201) gene transfer and radiation therapy in patients with non-small cell lung cancer...
  10. ncbi request reprint Clinical update of Ad-p53 gene therapy for lung cancer
    Stephen G Swisher
    University of Texas, M D Anderson Cancer Center, Department of Thoracic and Cardiovascular Surgery, Box 445, Houston, TX 77030, USA
    Surg Oncol Clin N Am 11:521-35. 2002
    ..It is hoped that these efforts will ultimately lead to a novel mode of therapy to complement conventional chemotherapy, radiation therapy, and surgical treatment strategies...
  11. ncbi request reprint Salvage esophagectomy for recurrent tumors after definitive chemotherapy and radiotherapy
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Thorac Cardiovasc Surg 123:175-83. 2002
    ..A subset of these patients have local relapse without distant metastases and therefore have no other curative intent treatment option but salvage esophagectomy...
  12. ncbi request reprint p53 Gene therapy for lung cancer
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston 77030, USA
    Curr Oncol Rep 4:334-40. 2002
    ..Further phase III studies are needed to determine if Ad-p53 will play a therapeutic role as a novel agent to treat non-small-cell lung cancer...
  13. ncbi request reprint Long-term outcome of phase II trial evaluating chemotherapy, chemoradiotherapy, and surgery for locoregionally advanced esophageal cancer
    Stephen G Swisher
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 57:120-7. 2003
    ..To evaluate the long-term outcome of chemotherapy, chemoradiotherapy, and surgery for patients with locoregionally advanced esophageal cancer...
  14. ncbi request reprint Failure patterns correlate with the proportion of residual carcinoma after preoperative chemoradiotherapy for carcinoma of the esophagus
    Pooja R Rohatgi
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:1349-55. 2005
    ..The current study was conducted to test the hypothesis that patterns of failure are correlated with the degree of residual carcinoma after preoperative chemoradiotherapy (CRT) in patients with esophageal carcinoma...
  15. pmc The role of consolidation therapy for stage III non-small cell lung cancer with persistent N2 disease after induction chemotherapy
    Arya Amini
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 94:914-20. 2012
    ..We assessed the role of consolidative therapies (postoperative radiation therapy and chemotherapy) for such patients...
  16. pmc Outcome of trimodality-eligible esophagogastric cancer patients who declined surgery after preoperative chemoradiation
    Takashi Taketa
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Oncology 83:300-4. 2012
    ..The literature on the outcome of such patients is sparse...
  17. ncbi request reprint Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma
    Julie G Izzo
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 25:698-707. 2007
    ..We hypothesized that CD1 A870 allele would be associated with higher CD1 protein expression, and increased genomic instability during EAC evolution, leading to more aggressive phenotype...
  18. ncbi request reprint Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer
    Xifeng Wu
    Department of Epidemiology, Experimental Therapeutics, GI Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:3789-98. 2006
    ..Understanding how specific genetic variants modify drug action pathways may provide informative blueprints for individualized chemotherapy...
  19. pmc A nomogram associated with high probability of malignant nodes in the surgical specimen after trimodality therapy of patients with oesophageal cancer
    Yuki Hayashi
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, United States
    Eur J Cancer 48:3396-404. 2012
    ..Currently, none of the clinical variables highly correlates with +ypNodes. We hypothesised that a combination of clinical variables could generate a model that associates with high likelihood of +ypNodes after trimodality in EC patients...
  20. doi request reprint Trimodality therapy without a platinum compound for localized carcinoma of the esophagus and gastroesophageal junction
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 116:1656-63. 2010
    ..It was hypothesized that chemoradiotherapy with fluoropyrimidine, taxane, and camptothecin would have preserved or improved efficacy with no compromise in safety...
  21. ncbi request reprint The number of lymph nodes with metastasis predicts survival in patients with esophageal or esophagogastric junction adenocarcinoma who receive preoperative chemoradiation
    Yan Gu
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:1017-25. 2006
    ..However, the prognostic significance of the number of LNs with residual metastasis remains unclear...
  22. doi request reprint Influence of induction chemotherapy and class of cytotoxics on pathologic response and survival after preoperative chemoradiation in patients with carcinoma of the esophagus
    Heta Javeri
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:1302-8. 2008
    ..Whether the type of therapy influences the outcomes remains largely unanswered. It is hypothesized that induction chemotherapy (IC) or the type of cytotoxics used would not influence patient outcomes...
  23. ncbi request reprint Preoperative induction of CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with locoregional carcinoma of the esophagus or gastroesophageal junction
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 100:2347-54. 2004
    ..Patients with localized esophageal carcinoma often develop locoregional and distant disease recurrence. The current study investigated the outcome of a new chemotherapy combination as induction therapy before chemoradiotherapy...
  24. ncbi request reprint The influence of histopathologic tumor viability on long-term survival and recurrence rates following neoadjuvant therapy for esophageal adenocarcinoma
    Ashleigh M Francis
    Departments of Thoracic and Cardiovascular Surgery, GI Medical Oncology, Diagnostic Radiology, GI Medicine and Nutrition, Pathology, Radiation Therapy, and Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
    Ann Surg 258:500-7. 2013
    ..Our aim was to validate the effect of histopathologic tumor viability (HTV) on extended survival outcomes and assess the prognostic ability of the current staging system in patients receiving preoperative chemoradiotherapy (CRT)...
  25. ncbi request reprint Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: association with poor outcome
    Kim L Wang
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 109:658-67. 2007
    ..It is not known whether EGFR plays a similar role in esophageal and EGJ adenocarcinomas...
  26. ncbi request reprint Preoperative chemoradiotherapy prior to esophagectomy in elderly patients is not associated with increased morbidity
    David C Rice
    Department of Thoracic and Cardiovascular Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 79:391-7; discussionn 391-7. 2005
    ..Preoperative chemotherapy and radiation therapy are often administered to patients with esophageal cancer. Despite an aging population, little data exist regarding feasibility of preoperative therapy in elderly patients...
  27. ncbi request reprint Comparison of clinical stage, therapy response, and patient outcome between squamous cell carcinoma and adenocarcinoma of the esophagus
    Pooja R Rohatgi
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Int J Gastrointest Cancer 36:69-76. 2005
    ..To analyze the differences in clinical stage, pathologic response to chemoradiotherapy, patterns of failure, and overall survival (OS) between patients with squamous cell carcinoma (SCC) and adenocarcinoma (ACA) of the esophagus...
  28. pmc Predictors of postoperative complications after trimodality therapy for esophageal cancer
    Jingya Wang
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Int J Radiat Oncol Biol Phys 86:885-91. 2013
    ..The goal of this study was to identify modifiable factors associated with postoperative complications after neoadjuvant chemoradiation...
  29. doi request reprint Visceral pleural invasion is not predictive of survival in patients with lung cancer and smaller tumor size
    Elizabeth David
    Department of Thoracic and Cardiovascular Surgery, University of Texas, MD Anderson Cancer Center, Houston, Texas, USA
    Ann Thorac Surg 95:1872-7; discussion 1877. 2013
    ..The purpose of this retrospective study was to evaluate the impact of VPI on disease-free survival (DFS) and overall survival (OS) in patients with node-negative NSCLC...
  30. pmc Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy
    Apar Pataer
    Departments of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Thorac Oncol 7:825-32. 2012
    ....
  31. doi request reprint The standardized uptake value of 18-fluorodeoxyglucose positron emission tomography after chemoradiation and clinical outcome in patients with localized gastroesophageal carcinoma
    Santosh B Murthy
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Oncology 78:316-22. 2010
    ..We hypothesized that the standardized uptake value (SUV) of positron emission tomography (PET) after chemoradiation would define the clinical outcome in patients...
  32. ncbi request reprint Impact of induction chemotherapy and preoperative chemoradiotherapy on operative morbidity and mortality in patients with locoregional adenocarcinoma of the stomach or gastroesophageal junction
    Kazumasa Fujitani
    Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Unit 444, P.O. Box 301402, Houston, TX 77230-1402, USA
    Ann Surg Oncol 14:1305-11. 2007
    ....
  33. doi request reprint Influence of the baseline 18F-fluoro-2-deoxy-D-glucose positron emission tomography results on survival and pathologic response in patients with gastroesophageal cancer undergoing chemoradiation
    Heta Javeri
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:624-30. 2009
    ..The authors evaluated initial standardized unit value (iSUV) of 18F-fluoro-2-deoxy-D-glucose positron emission tomography and its association with overall survival and the degree of pathologic response after surgery...
  34. ncbi request reprint Postoperative pulmonary complications after preoperative chemoradiation for esophageal carcinoma: correlation with pulmonary dose-volume histogram parameters
    Hoon K Lee
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 57:1317-22. 2003
    ..To clarify the relationship between the percentage of lung receiving low radiation doses with concurrent chemotherapy and the occurrence of postoperative pulmonary complications in the treatment of esophageal carcinoma...
  35. ncbi request reprint Preoperative chemo-radiation-induced ulceration in patients with esophageal cancer: a confounding factor in tumor response assessment in integrated computed tomographic-positron emission tomographic imaging
    Jeremy J Erasmus
    Department of Diagnostic Imaging, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Thorac Oncol 1:478-86. 2006
    ..We evaluated the use of integrated computed tomography (CT)-PET among patients with esophageal cancer being considered for resection after CRT...
  36. doi request reprint Omental reinforcement of the thoracic esophagogastric anastomosis: an analysis of leak and reintervention rates in patients undergoing planned and salvage esophagectomy
    Boris Sepesi
    Department of Thoracic and Cardiovascular Surgery, MD Anderson Cancer Center, Houston, TX, USA
    J Thorac Cardiovasc Surg 144:1146-50. 2012
    ..An uncontained thoracic anastomotic leak may cause severe morbidity or mortality. Thoracic transposition of an omental flap along with the gastric conduit may decrease leak incidence, severity, or need for reoperations after esophagectomy...
  37. ncbi request reprint Esophagectomy after concurrent chemoradiotherapy improves locoregional control in clinical stage II or III esophageal cancer patients
    Zhongxing Liao
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 60:1484-93. 2004
    ..To evaluate the effect of surgical resection on the outcome of patients with clinical Stage II or III cancer of the esophagus treated with concurrent chemoradiotherapy...
  38. ncbi request reprint The addition of induction chemotherapy to preoperative, concurrent chemoradiotherapy improves tumor response in patients with esophageal adenocarcinoma
    S Chris Malaisrie
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:967-74. 2006
    ..In this study, the authors evaluated the efficacy of CCRT compared with traditional concurrent chemoradiotherapy (CRT)...
  39. doi request reprint Association of age and survival in patients with gastroesophageal cancer undergoing surgery with or without preoperative therapy
    Fadi Braiteh
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 115:4450-8. 2009
    ..For this study, the authors explored their institution's large surgical experience to examine the impact of age on long-term patient survival and surgical complications...
  40. doi request reprint Video-assisted thoracoscopic versus open thoracotomy lobectomy in a cohort of 13,619 patients
    Raja R Gopaldas
    the Texas Heart Institute at St Luke s Episcopal Hospital, Houston, Texas, USA
    Ann Thorac Surg 89:1563-70. 2010
    ..However, the issue of whether VATS or open thoracotomy is better remains controversial. We compared outcomes of open and VATS lobectomy in a national database...
  41. ncbi request reprint Excellent interobserver agreement on grading the extent of residual carcinoma after preoperative chemoradiation in esophageal and esophagogastric junction carcinoma: a reliable predictor for patient outcome
    Tsung Teh Wu
    Department of Pathology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Surg Pathol 31:58-64. 2007
    ..The extent of residual carcinoma is a reliable and reproducible predictor of survival; this grading system may allow a novel and early means of comparing outcomes after different neoadjuvant treatment regimens...
  42. ncbi request reprint Adenoviral melanoma differentiation-associated gene 7 induces apoptosis in lung cancer cells through mitochondrial permeability transition-independent cytochrome c release
    Abujiang Pataer
    Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, and Introgen Therapeutics Inc, Houston, TX 77030, USA
    J Thorac Cardiovasc Surg 125:1328-35. 2003
    ..The mechanisms of action are not well defined but may involve release of cytochrome c from the mitochondria with subsequent caspase activation...
  43. doi request reprint Lymphovascular invasion as a tool to further subclassify T1b esophageal adenocarcinoma
    Putao Cen
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 112:1020-7. 2008
    ..The authors hypothesized that LVI status would subclassify T1b cancers and facilitate new therapeutic strategies...
  44. ncbi request reprint The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells
    Kerry A Sieger
    Introgen Therapeutics, Inc, Houston, TX 77030, USA
    Mol Ther 9:355-67. 2004
    ..Only full-length and ER-targeted MDA-7 elicited cell death in tumor cells. Thus in lung cancer cells, Ad-mda7 activates the UPR stress pathway and induces apoptosis via intracellular MDA-7 expression in the secretory pathway...
  45. doi request reprint Predictors of recurrent pulmonary metastases and survival after pulmonary metastasectomy for colorectal cancer
    Shanda H Blackmon
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, and Department of Surgery, The Methodist Hospital, Houston, Texas 77030, USA
    Ann Thorac Surg 94:1802-9. 2012
    ..The objective of this study was to identify preoperative predictors of survival and lung recurrence for patients undergoing resection of such lesions...
  46. ncbi request reprint Detection of interval distant metastases: clinical utility of integrated CT-PET imaging in patients with esophageal carcinoma after neoadjuvant therapy
    John F Bruzzi
    Division of Diagnostic Imaging, M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 109:125-34. 2007
    ....
  47. doi request reprint The higher the decrease in the standardized uptake value of positron emission tomography after chemoradiation, the better the survival of patients with gastroesophageal adenocarcinoma
    Heta Javeri
    Department of Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 115:5184-92. 2009
    ..Analyses of dichotomized data are commonly reported. The authors analyzed percentage SUV decrease as both dichotomized and continuous variables...
  48. doi request reprint Progression after chemotherapy is a novel predictor of poor outcomes after pulmonary metastasectomy in sarcoma patients
    Elizabeth H Stephens
    Methodist Hospital, Houston, TX, USA
    J Am Coll Surg 212:821-6. 2011
    ..We hypothesized that measurable progression after chemotherapy is a novel predictor of poor outcomes in sarcoma patients undergoing pulmonary metastasectomy...
  49. ncbi request reprint Signet-ring cell or mucinous histology after preoperative chemoradiation and survival in patients with esophageal or esophagogastric junction adenocarcinoma
    Lucian R Chirieac
    Department of Pathology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Clin Cancer Res 11:2229-36. 2005
    ..Some adenocarcinomas have mixed patterns, including signet-ring cell and mucinous histology, but the clinical significance of these subtypes is unknown...
  50. ncbi request reprint Gene therapy with E2F-1 up-regulates the protein kinase PKR and inhibits growth of leiomyosarcoma in vivo
    Stephan A Vorburger
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, Texas 77030 4009, USA
    Mol Cancer Ther 4:1710-6. 2005
    ..Taken together, these data suggest that E2F-1 gene therapy and PKR modulation might be a promising treatment strategy for these tumors that are highly resistant to conventional therapies...
  51. pmc Treatment outcomes of resected esophageal cancer
    Wayne Hofstetter
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg 236:376-84; discussion 384-5. 2002
    ..To assess the evolution of treatment and outcome for resected esophageal cancer at a single institution...
  52. ncbi request reprint Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma
    Julie G Izzo
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 24:748-54. 2006
    ..Nuclear factor kappaB (NF-kappaB), a transcriptional factor, is constitutively activated or treatment induced in esophageal cancer and may influence treatment outcomes...
  53. doi request reprint Duplicated muscularis mucosae invasion has similar risk of lymph node metastasis and recurrence-free survival as intramucosal esophageal adenocarcinoma
    Jeannelyn S Estrella
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
    Am J Surg Pathol 35:1045-53. 2011
    ..EAC invasion into the space between duplicated MM confers a similar risk of lymph node metastasis and recurrence as those of intramucosal EAC, and LVI is the best predictor of lymph node status and RFS in pT1 EAC...
  54. ncbi request reprint Value of baseline positron emission tomography for predicting overall survival in patient with nonmetastatic esophageal or gastroesophageal junction carcinoma
    David Hong
    Department of GI Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:1620-6. 2005
    ..The authors tested the hypothesis that, in this setting, the number of PET abnormalities (NPA) would correlate with OS and DFS...
  55. ncbi request reprint Endoscopic ultrasonography-identified celiac adenopathy remains a poor prognostic factor despite preoperative chemoradiotherapy in esophageal adenocarcinoma
    S Chris Malaisrie
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 131:65-72. 2006
    ..We reviewed our experience with preoperative chemoradiotherapy in patients with adenocarcinoma of the distal esophagus and pretreatment endoscopic ultrasonography-identified celiac adenopathy...
  56. pmc Does the timing of esophagectomy after chemoradiation affect outcome?
    Jae Y Kim
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Ann Thorac Surg 93:207-12; discussion 212-3. 2012
    ..However, there are theoretical concerns that waiting longer after radiation may lead to a more difficult operation and more complications. The optimal timing of esophagectomy after CXRT is unknown...
  57. ncbi request reprint Posttherapy pathologic stage predicts survival in patients with esophageal carcinoma receiving preoperative chemoradiation
    Lucian R Chirieac
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:1347-55. 2005
    ....
  58. doi request reprint Anti-phosphorylated histone H3 expression in Barrett's esophagus, low-grade dysplasia, high-grade dysplasia, and adenocarcinoma
    Mahmoud Goodarzi
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Mod Pathol 22:1612-21. 2009
    ..In addition, phosphorylated histone H3 is a potential supportive marker to histology in differentiating low-grade dysplasia from indefinite for dysplasia and high-grade dysplasia from adenocarcinoma in the mucosal biopsy samples...
  59. ncbi request reprint Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR
    Abujiang Pataer
    Department of Thoracic and Cardiovascular Surgery, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston, TX 77030, USA
    Mol Ther 11:717-23. 2005
    ....
  60. ncbi request reprint Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma
    David C Rice
    Department of Thoracic and Cardiovascular Surgery, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 84:1685-92; discussion 1692-3. 2007
    ..To improve local control, we have used intensity-modulated radiation therapy (IMRT) as it allows better dose distribution to regions at risk of recurrence as well as reduced radiation to surrounding organs...
  61. ncbi request reprint Histologic subtypes as determinants of outcome in esophageal carcinoma patients with pathologic complete response after preoperative chemoradiotherapy
    Pooja R Rohatgi
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:552-8. 2006
    ..The current study tested the hypothesis that the clinical outcome of patients with localized esophageal carcinoma after preoperative chemoradiotherapy (CTRT) depends on histology...
  62. ncbi request reprint Characterization of pathologic complete response after preoperative chemoradiotherapy in carcinoma of the esophagus and outcome after pathologic complete response
    Pooja Rohatgi
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:2365-72. 2005
    ....
  63. ncbi request reprint Role for the double-stranded RNA-activated protein kinase PKR in Ad-TNF-alpha gene therapy in esophageal cancer
    Urs von Holzen
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Surgery 138:261-8. 2005
    ..We, therefore, evaluated the role of PKR in Ad-TNF-alpha-induced apoptosis in esophageal cancer cells...
  64. ncbi request reprint The significance of neuroendocrine differentiation in adenocarcinoma of the esophagus and esophagogastric junction after preoperative chemoradiation
    Kim L Wang
    Departments of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 107:1467-74. 2006
    ....
  65. ncbi request reprint Polymorphism at the 3'-UTR of the thymidylate synthase gene: a potential predictor for outcomes in Caucasian patients with esophageal adenocarcinoma treated with preoperative chemoradiation
    Zhongxing Liao
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 64:700-8. 2006
    ..To test the hypothesis that TS3'UTR polymorphisms predict outcomes in 146 Caucasian patients with esophageal adenocarcinoma treated with preoperative 5-fluorouracil-based chemoradiation...
  66. ncbi request reprint Impact of induction chemotherapy and preoperative chemoradiotherapy on operative morbidity and mortality in patients with locoregional adenocarcinoma of the stomach or gastroesophageal junction
    Kazumasa Fujitani
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Ann Surg Oncol 14:2010-7. 2007
    ....
  67. ncbi request reprint The evolution of treatment outcomes for resected stage IIIA non-small cell lung cancer over 16 years at a single institution
    Linda W Martin
    Departments of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex, USA
    J Thorac Cardiovasc Surg 130:1601-10. 2005
    ..To determine which treatment factors are associated with improved survival, we evaluated outcomes for these patients at our institution over a 16-year period...
  68. pmc 3p22.1 and 10q22.3 deletions detected by fluorescence in situ hybridization (FISH): a potential new tool for early detection of non-small cell lung Cancer (NSCLC)
    Sai Yendamuri
    Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, New York, USA
    J Thorac Oncol 3:979-84. 2008
    ..1 and 10q22.3 by fluorescent in situ hybridization (FISH) and to examine their distribution in different areas of the airway in patients with non-small cell lung cancer...
  69. pmc Combined modality therapy of cT2N0M0 esophageal cancer: the University of Texas M. D. Anderson Cancer Center experience
    Panteleimon Kountourakis
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 117:925-30. 2011
    ..This study analyzed the largest series of consecutive cT2N0M0 esophageal cancer patients treated with preoperative chemoradiotherapy...
  70. ncbi request reprint The double-stranded RNA-activated protein kinase mediates radiation resistance in mouse embryo fibroblasts through nuclear factor kappaB and Akt activation
    Urs von Holzen
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 13:6032-9. 2007
    ..There have been no reports to date about the role of PKR in radiation sensitivity...
  71. pmc Prognostic significance of differentially expressed miRNAs in esophageal cancer
    Yuxin Hu
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX77030, USA
    Int J Cancer 128:132-43. 2011
    ..Our data indicate that further evaluation of miR-30e and miR-16-2 as prognostic biomarkers is warranted in patients with esophageal adenocarcinoma. In addition, the role of miR-34a in esophageal cancer also warrants further study...
  72. ncbi request reprint Significance of the depth of tumor invasion and lymph node metastasis in superficially invasive (T1) esophageal adenocarcinoma
    Lixia Liu
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 29:1079-85. 2005
    ....
  73. doi request reprint Critical role of surgery in patients with gastroesophageal carcinoma with a poor prognosis after chemoradiation as defined by positron emission tomography
    Srikrishna V Patnana
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:4487-94. 2010
    ..High SUV (HSUV) after chemoradiation portends a poor prognosis. The authors retrospectively examined the role of surgery in patients with HSUV after chemoradiation...
  74. pmc Genome-wide catalogue of chromosomal aberrations in barrett's esophagus and esophageal adenocarcinoma: a high-density single nucleotide polymorphism array analysis
    Jian Gu
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Unit 1340, 1155 Pressler Boulevard, Houston, TX 77030, USA
    Cancer Prev Res (Phila) 3:1176-86. 2010
    ..8q24 (containing Myc) and 8p23.1 (containing CTSB) were the two most frequently amplified regions. In addition, a significant trend toward increasing amplification was associated with higher progression stage...
  75. doi request reprint A clinical nomogram predicting pathologic lymph node involvement in esophageal cancer patients
    Puja Gaur
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Ann Surg 252:611-7. 2010
    ..We, therefore, constructed a nomogram to predict the risk of pN1 prior to surgical resection and externally validated the clinical utility of the model...
  76. ncbi request reprint Retrospective study of clinicopathologic features and prognosis of high-grade neuroendocrine carcinoma of the esophagus
    Dipen M Maru
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 32:1404-11. 2008
    ..031). There was no difference in prognosis between patients with large-cell NEC and those with small-cell neuroendocrine carcinoma. Esophageal NEC is an aggressive tumor, and patients with mix NEC have better outcome...
  77. doi request reprint Superior sulcus tumors with vertebral body involvement: a multimodality approach
    William D Bolton
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 137:1379-87. 2009
    ..We have previously documented a 2-year survival of 54% in patients treated with a multimodality approach. This work builds on our previous experience and examines the long-term outcomes...
  78. ncbi request reprint Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma
    Charles Lu
    Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 23:3495-501. 2005
    ..To determine pathologic response rates to liposome-entrapped cis-bisneodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) (L-NDDP) administered intrapleurally in patients with malignant pleural mesothelioma...
  79. ncbi request reprint Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR)
    Abujiang Pataer
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Res 62:2239-43. 2002
    ..Additionally, PKR null but not wild-type fibroblasts are resistant to Ad-mda7-induced apoptosis. These results suggest that the activation of PKR and its downstream targets may be a critical pathway for Ad-mda7-mediated apoptosis...
  80. ncbi request reprint Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis
    Jian Gu
    Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Oncogene 23:1300-7. 2004
    ..Our data suggest that Ad-p53 induces the expression of a variety of proapoptotic genes and that lack of induction in one of these genes does not block Ad/p53-mediated cell killing in human lung cancer cells...
  81. ncbi request reprint Positron emission tomography imaging in nonsmall-cell lung cancer
    Jeremy J Erasmus
    Division of Diagnostic Imaging, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 110:2155-68. 2007
    ..The article discusses the diagnosis, staging, and assessment of treatment response and prognosis with an emphasis on the appropriate clinical use of PET in management...
  82. pmc MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus
    Dipen M Maru
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA
    Am J Pathol 174:1940-8. 2009
    ..In conclusion, this study identified miR-196a as a potential marker of progression of BE and KRT5, SPRR2C, and S100A9 as its targets...
  83. doi request reprint Patterns of care and locoregional treatment outcomes in older esophageal cancer patients: The SEER-Medicare Cohort
    Grace L Smith
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Int J Radiat Oncol Biol Phys 74:482-9. 2009
    ..Optimal management of elderly patients with nonmetastatic esophageal cancer is unclear. Outcomes data after locoregional treatment are lacking for this group...
  84. ncbi request reprint Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis
    Stephan A Vorburger
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, TX 77030, USA
    Oncogene 21:6278-88. 2002
    ..We conclude that an important pathway of E2F-1-mediated apoptosis is dependent on PKR activation and does not require p53 or p73...
  85. ncbi request reprint Management of intrathoracic leaks following esophagectomy
    Linda W Martin
    Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Unit 445, PO Box 301402, Houston, TX 77230 1402, USA
    Adv Surg 40:173-90. 2006
    ..With further advances in surgical technique, critical care, and multimodality treatment, this trend is likely to continue...
  86. ncbi request reprint Expression of annexin A1 in esophageal and esophagogastric junction adenocarcinomas: association with poor outcome
    Kim L Wang
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Clin Cancer Res 12:4598-604. 2006
    ..However, the role of ANXA1 in esophageal adenocarcinoma is unclear. Our goal was to evaluate ANXA1 expression and determine its prognostic significance in adenocarcinoma of the esophagus and esophagogastric junction...
  87. doi request reprint Pathologic T0N1 esophageal cancer after neoadjuvant therapy and surgery: an orphan status
    Min P Kim
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 90:884-90; discussion 890-1. 2010
    ..We hypothesized that these patients would have similar survival to patients with incomplete response to therapy...
  88. doi request reprint Prognosis and reevaluation of lung cancer by positron emission tomography imaging
    Jeremy J Erasmus
    M D Anderson Cancer Center, Division of Diagnostic Imaging, Houston, TX 77030, USA
    Proc Am Thorac Soc 6:171-9. 2009
    ..This article will discuss the assessment of prognosis and treatment response in patients with non-small cell lung cancer using FDG-PET, and will emphasize potential advantages and limitations in clinical management...
  89. ncbi request reprint Comparison of limited surgery and three-dimensional conformal radiation in high-risk patients with stage I non-small cell lung cancer
    Sai Yendamuri
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Thorac Oncol 2:1022-8. 2007
    ..In this study, we retrospectively compared the outcome of patients treated with wedge resection or three-dimensional (3-D) conformal radiation therapy, the most common treatment modalities used for such high-risk patients...
  90. ncbi request reprint Value of endoscopic ultrasound staging in conjunction with the evaluation of lymphovascular invasion in identifying low-risk esophageal carcinoma
    Putao Cen
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 112:503-10. 2008
    ..It was hypothesized that endoscopic ultrasonography (EUS) in concert with detailed histopathologic evaluation would identify low-risk cancers for an appropriate but organ-preserving strategy...
  91. ncbi request reprint Differential response to preoperative chemoradiation and surgery in esophageal adenocarcinomas based on presence of Barrett's esophagus and symptomatic gastroesophageal reflux
    Banke Agarwal
    Department of Gastrointestinal Medicine and Nutrition, M D Anderson Cancer Center, Houston, Texas, USA
    Ann Thorac Surg 79:1716-23. 2005
    ..In this study, we investigated potential differences in clinical outcomes in esophageal adenocarcinoma patients based on the presence of identifiable Barrett's mucosa and/or history of symptomatic GERD...
  92. ncbi request reprint Extended surgical staging for potentially resectable malignant pleural mesothelioma
    David C Rice
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 80:1988-92; discussion 1992-3. 2005
    ..We evaluated the role of extended surgical staging procedures, which generally includes a combination of laparoscopy, peritoneal lavage, and mediastinoscopy, to more precisely stage patients with MPM...
  93. ncbi request reprint Long-segment, supercharged, pedicled jejunal flap for total esophageal reconstruction
    Anthony J Ascioti
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 130:1391-8. 2005
    ..Few reports describe this technique in patients with cancer. We report our initial experience with "supercharged" pedicled jejunum as an alternative conduit for total esophageal reconstruction...
  94. ncbi request reprint Gene expression profiling of localized esophageal carcinomas: association with pathologic response to preoperative chemoradiation
    Rajyalakshmi Luthra
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77054, USA
    J Clin Oncol 24:259-67. 2006
    ..Currently, however, there are no tools to help select optimum therapy. We hypothesized that gene expression profiling could provide clues and biomarkers for selection of therapy...
  95. ncbi request reprint Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients
    Ara A Vaporciyan
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston, TX 77030, USA
    J Thorac Cardiovasc Surg 127:779-86. 2004
    ..The purpose of this study was to identify risk factors associated with the onset of atrial fibrillation after thoracic surgery to allow more targeted interventions in patients with the highest risk...
  96. pmc Prognostic significance of RNA-dependent protein kinase on non-small cell lung cancer patients
    Abujiang Pataer
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Clin Cancer Res 16:5522-8. 2010
    ..To explore the role of PKR in human lung cancer, we evaluated the expression of PKR in tissue microarray (TMA) specimens from both non-small cell lung cancer (NSCLC) and normal human bronchial epithelium tissue...
  97. doi request reprint Frequent loss of heterozygosity of chromosome 1q in esophageal adenocarcinoma: loss of chromosome 1q21.3 is associated with shorter overall survival
    Dipen M Maru
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:1576-85. 2009
    ..It was unclear whether this difference was due to loss of heterozygosity (LOH) or to other genetic alterations at this locus...
  98. pmc Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity
    Abujiang Pataer
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Biol Ther 8:245-52. 2009
    ..Our results suggest a rationale to develop therapeutic strategies that target PKR signaling in human cancer cells...
  99. doi request reprint Endoscopic ultrasound-guided fine needle aspiration for staging of malignant pleural mesothelioma
    David C Rice
    Department of Thoracic and Cardiovascular Surgery, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Thorac Surg 88:862-8; discussion 868-9. 2009
    ....
  100. pmc Adenoviral endoplasmic reticulum-targeted mda-7/interleukin-24 vector enhances human cancer cell killing
    Abujiang Pataer
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Mol Cancer Ther 7:2528-35. 2008
    ..These findings suggest that vectors targeting the ER (Ad-ER-mda7) may be more effective in cancer gene therapy possibly through more effective induction or ER stress pathways...
  101. ncbi request reprint Incidence of major pulmonary morbidity after pneumonectomy: association with timing of smoking cessation
    Ara A Vaporciyan
    Department of Thoracic and Cardiovascular Surgery and Medical Informatics, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Ann Thorac Surg 73:420-5; discussion 425-6. 2002
    ..The purpose of this study was to identify preoperative and perioperative factors associated with the development of MPEs after pneumonectomy to help predict which patients are at increased risk for MPEs...