Lisa M Sullivan
Affiliation: The Children's Hospital of Philadelphia
- Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletionsLisa M Sullivan
Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA
Mod Pathol 26:385-92. 2013..Given the high percentage of SMARCB1 alterations in epithelioid sarcoma, these findings argue against using SMARCB1 gene deletion as a tool in distinguishing them from malignant rhabdoid tumors...
- Claudin-6 is a nonspecific marker for malignant rhabdoid and other pediatric tumorsLisa M Sullivan
Department of Pathology and Laboratory Medicine, Children s Hospital of Philadelphia, Philadelphia, PA, USA
Am J Surg Pathol 36:73-80. 2012..Although CLDN6 is expressed in both AT/RTs and MRTs, it is not a specific biomarker as it is expressed in a variety of other pediatric CNS and soft tissue tumors...
- Immunohistochemical expression of glypican-3 in pediatric tumors: an analysis of 414 casesElaine S Chan
Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Dev Pathol 16:272-7. 2013..0001) in addition to negative INI1/BAF47/SMARCB1 staining to differentiate atypical teratoid rhabdoid tumors from other high-grade pediatric brain tumors...
- Clinical utilization of high-resolution single nucleotide polymorphism based oligonucleotide arrays in diagnostic studies of pediatric patients with solid tumorsMargaret J Dougherty
Division of Human Genetics, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Cancer Genet 205:42-54. 2012..Based on our experience in the last 2 1/2 years, we suggest that SNP array analysis can be used as a first tier clinical test for the majority of pediatric solid tumors...
- Malignant rhabdoid tumors express stem cell factors, which relate to the expression of EZH2 and Id proteinsSriram Venneti
Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am J Surg Pathol 35:1463-72. 2011..This study underscores similarities between MRTs and stem cells and may help elucidate common biologic pathways that could serve in advancing more effective therapeutic strategies to treat MRTs...