- PurityEst: estimating purity of human tumor samples using next-generation sequencing dataXiaoping Su
Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Bioinformatics 28:2265-6. 2012..We applied our tool to a whole cancer genome sequencing datasets and demonstrated the accuracy of PurityEst compared with DNA copy number-based estimation...
- VirusSeq: software to identify viruses and their integration sites using next-generation sequencing of human cancer tissueYunxin Chen
Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Bioinformatics 29:266-7. 2013..Using these data, we showed that VirusSeq accurately detects the known viruses and their integration sites with high sensitivity and specificity. VirusSeq can also perform this function using whole-genome sequencing data of human tissue...