LISA T STOWERS

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi request reprint What is a pheromone? Mammalian pheromones reconsidered
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Neuron 46:699-702. 2005
  2. pmc Analysis of male pheromones that accelerate female reproductive organ development
    Kelly A Flanagan
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America
    PLoS ONE 6:e16660. 2011
  3. pmc Species specificity in major urinary proteins by parallel evolution
    Darren W Logan
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America
    PLoS ONE 3:e3280. 2008
  4. pmc Ominous odors: olfactory control of instinctive fear and aggression in mice
    Lisa Stowers
    The Scripps Research Institute, Department of Molecular and Cellular Neuroscience, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 23:339-45. 2013
  5. pmc Sexual dimorphism in olfactory signaling
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, ICND222, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 20:770-5. 2010
  6. pmc Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 20:274-80. 2010
  7. doi request reprint LUSH shapes up for a starring role in olfaction
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell 133:1137-9. 2008
  8. pmc The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs
    Fabio Papes
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell 141:692-703. 2010
  9. ncbi request reprint Identification of protein pheromones that promote aggressive behaviour
    Pablo Chamero
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92030, USA
    Nature 450:899-902. 2007
  10. ncbi request reprint Neuronal development: specifying a hard-wired circuit
    Lisa Stowers
    The Scripps Research Institute, 10550 North Torrey Pines Road, ICND 222, La Jolla, California 92037, USA
    Curr Biol 14:R62-4. 2004

Collaborators

  • Darren W Logan
  • Kelly A Flanagan
  • Fabio Papes
  • Tobias F Marton
  • Pablo Chamero
  • William Webb
  • Jason R Cruz
  • Benjamin F Cravatt
  • Kelly Flanagan
  • Alan Saghatelian

Detail Information

Publications10

  1. ncbi request reprint What is a pheromone? Mammalian pheromones reconsidered
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Neuron 46:699-702. 2005
    ..Recent discoveries of potential pheromones reveal that they may be more structurally and functionally diverse than previously defined...
  2. pmc Analysis of male pheromones that accelerate female reproductive organ development
    Kelly A Flanagan
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America
    PLoS ONE 6:e16660. 2011
    ..When directly analyzed, we are unable to detect previously known pheromones in urine fractions that generate uterine growth. Our analysis indicates that pheromones emitted by males to advance female puberty remain to be identified...
  3. pmc Species specificity in major urinary proteins by parallel evolution
    Darren W Logan
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America
    PLoS ONE 3:e3280. 2008
    ..Our findings illustrate that increasing genomic complexity of the Mup gene family is not evolutionarily isolated, but is instead a recurring mechanism of generating coding diversity consistent with a species-specific function in mammals...
  4. pmc Ominous odors: olfactory control of instinctive fear and aggression in mice
    Lisa Stowers
    The Scripps Research Institute, Department of Molecular and Cellular Neuroscience, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 23:339-45. 2013
    ..A sensory-initiated comparative study of these two fundamental threat reactions promises to offer new mechanistic insight...
  5. pmc Sexual dimorphism in olfactory signaling
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, ICND222, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 20:770-5. 2010
    ..However, first progress has been made in identifying components of sexually dimorphic olfactory circuits in both Drosophila and the mouse...
  6. pmc Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 20:274-80. 2010
    ..This review focuses on these non-VNO receptors and neurons, and evaluates their potential for mediating stereotyped olfactory behavior in mammals...
  7. doi request reprint LUSH shapes up for a starring role in olfaction
    Lisa Stowers
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell 133:1137-9. 2008
    ..Instead, LUSH undergoes a conformational change upon pheromone binding that is sufficient for neuronal activation...
  8. pmc The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs
    Fabio Papes
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell 141:692-703. 2010
    ..This co-option of existing sensory mechanisms provides a molecular solution to the difficult problem of evolving a variety of species-specific molecular detectors...
  9. ncbi request reprint Identification of protein pheromones that promote aggressive behaviour
    Pablo Chamero
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92030, USA
    Nature 450:899-902. 2007
    ..Our results substantiate the idea of MUP proteins as pheromone ligands that mediate male-male aggression through the accessory olfactory neural pathway...
  10. ncbi request reprint Neuronal development: specifying a hard-wired circuit
    Lisa Stowers
    The Scripps Research Institute, 10550 North Torrey Pines Road, ICND 222, La Jolla, California 92037, USA
    Curr Biol 14:R62-4. 2004
    ..But direct visualization of second order neurons in Drosophila now suggests that dendritic targeting occurs independently of interactions with incoming sensory neurons...

Research Grants9

  1. Characteristics of Pheromone Binding Proteins
    Lisa Stowers; Fiscal Year: 2007
    ..3) Define the function of liver specific MUPs in regulating social behavior. These aims will be tested using genomic and molecular genetic strategies to elucidate the extent to which MUPs function in pheromone signaling. ..
  2. Identification of the ligands and sensory neurons that mediate pheromone behavior
    Lisa Stowers; Fiscal Year: 2009
    ..This important first step will allow us to predictably activate social responses in mice, and therefore define at the cellular and molecular level, the underlying mechanisms of neural function and dysfunction. ..
  3. Identification of the ligands and sensory neurons that mediate pheromone behavior
    LISA T STOWERS; Fiscal Year: 2010
    ..This important first step will allow us to predictably activate social responses in mice, and therefore define at the cellular and molecular level, the underlying mechanisms of neural function and dysfunction. ..
  4. Identification of the ligands and sensory neurons that mediate pheromone behavior
    Lisa Stowers; Fiscal Year: 2009
    ..This important first step will allow us to predictably activate social responses in mice, and therefore define at the cellular and molecular level, the underlying mechanisms of neural function and dysfunction. ..
  5. Characteristics of Pheromone Binding Proteins
    Lisa Stowers; Fiscal Year: 2004
    ..3) Define the function of liver specific MUPs in regulating social behavior. These aims will be tested using genomic and molecular genetic strategies to elucidate the extent to which MUPs function in pheromone signaling. ..
  6. Characteristics of Pheromone Binding Proteins
    Lisa Stowers; Fiscal Year: 2005
    ..3) Define the function of liver specific MUPs in regulating social behavior. These aims will be tested using genomic and molecular genetic strategies to elucidate the extent to which MUPs function in pheromone signaling. ..
  7. Characteristics of Pheromone Binding Proteins
    Lisa Stowers; Fiscal Year: 2006
    ..3) Define the function of liver specific MUPs in regulating social behavior. These aims will be tested using genomic and molecular genetic strategies to elucidate the extent to which MUPs function in pheromone signaling. ..
  8. Identification of the ligands and sensory neurons that mediate pheromone behavior
    Lisa Stowers; Fiscal Year: 2009
    ..This important first step will allow us to predictably activate social responses in mice, and therefore define at the cellular and molecular level, the underlying mechanisms of neural function and dysfunction. ..