Klaus M Stiefel

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. pmc The effects of cholinergic neuromodulation on neuronal phase-response curves of modeled cortical neurons
    Klaus M Stiefel
    Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    J Comput Neurosci 26:289-301. 2009
  2. pmc Intrinsic subthreshold oscillations extend the influence of inhibitory synaptic inputs on cortical pyramidal neurons
    Klaus M Stiefel
    Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA
    Eur J Neurosci 31:1019-26. 2010
  3. pmc Origin of intrinsic irregular firing in cortical interneurons
    Klaus M Stiefel
    Computational Neurobiology Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 110:7886-91. 2013
  4. pmc Irregular firing of isolated cortical interneurons in vitro driven by intrinsic stochastic mechanisms
    Bernhard Englitz
    Computational Neuroscience Laboratory, Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Neural Comput 20:44-64. 2008
  5. pmc Model of traveling waves in a coral nerve network
    Eugenia Chen
    Computational Neurobiology Laboratory and Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:195-200. 2008
  6. pmc Cholinergic neuromodulation changes phase response curve shape and type in cortical pyramidal neurons
    Klaus M Stiefel
    Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS ONE 3:e3947. 2008

Detail Information

Publications6

  1. pmc The effects of cholinergic neuromodulation on neuronal phase-response curves of modeled cortical neurons
    Klaus M Stiefel
    Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    J Comput Neurosci 26:289-301. 2009
    ..In all of these models a decrease in the amount of a spike-frequency adaptation current was a necessary and sufficient condition for the shape of the PRC to change from biphasic (type II) to purely positive (type I)...
  2. pmc Intrinsic subthreshold oscillations extend the influence of inhibitory synaptic inputs on cortical pyramidal neurons
    Klaus M Stiefel
    Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA
    Eur J Neurosci 31:1019-26. 2010
    ..These results show that the intrinsic conductances of cortical pyramidal neurons can carry information about inhibitory inputs and can extend the integration window for synaptic input...
  3. pmc Origin of intrinsic irregular firing in cortical interneurons
    Klaus M Stiefel
    Computational Neurobiology Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 110:7886-91. 2013
    ..This explanation holds over a wide parameter range and with Gaussian white, power-law, and Ornstein-Uhlenbeck noise. The intrinsically irregular spiking of interneurons could contribute to the irregularity of the cortical network...
  4. pmc Irregular firing of isolated cortical interneurons in vitro driven by intrinsic stochastic mechanisms
    Bernhard Englitz
    Computational Neuroscience Laboratory, Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Neural Comput 20:44-64. 2008
    ..This result has important consequences for the origin of fluctuations observed in the cortex in vivo...
  5. pmc Model of traveling waves in a coral nerve network
    Eugenia Chen
    Computational Neurobiology Laboratory and Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:195-200. 2008
    ..In a second stage, we used these neurons as the starting point for the optimization of a two-dimensional nerve net. This strategy yielded a network with parameters that reproduced the experimentally observed spread of excitation...
  6. pmc Cholinergic neuromodulation changes phase response curve shape and type in cortical pyramidal neurons
    Klaus M Stiefel
    Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS ONE 3:e3947. 2008
    ..This is the first report showing that cholinergic neuromodulation may cause a qualitative switch in the PRCs type implying a change in the fundamental dynamical mechanism of spike generation...