Affiliation: The John B. Pierce Laboratory
Country: USA


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    Stachenfeld N, Keefe D. Estrogen effects on osmotic regulation of AVP and fluid balance. Am J Physiol Endocrinol Metab. 2002;283:E711-21 pubmed
    ..Renal sensitivity to AVP may be lower during E due to intrarenal effects on water and sodium excretion. E/P increased sodium retention and renin-angiotensin-aldosterone stimulation. ..
  2. Stachenfeld N. Acute effects of sodium ingestion on thirst and cardiovascular function. Curr Sports Med Rep. 2008;7:S7-13 pubmed publisher
  3. Stachenfeld N, Leone C, Mitchell E, Freese E, Harkness L. Water intake reverses dehydration associated impaired executive function in healthy young women. Physiol Behav. 2018;185:103-111 pubmed publisher
    ..These deficits were reversed by drinking water to the European Food Safety Authority and Institute of Medicine requirements of 2.5l/day for adult women. ..
  4. Stachenfeld N. Sex hormone effects on autonomic and endothelial function. Exp Physiol. 2016;101:347-8 pubmed publisher
    ..A video slideshow Introduction to the Symposium by symposium organiser Nina S. Stachenfeld can be found here. ..
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    Stachenfeld N, Dipietro L, Kokoszka C, Silva C, Keefe D, Nadel E. Physiological variability of fluid-regulation hormones in young women. J Appl Physiol (1985). 1999;86:1092-6 pubmed
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    Stachenfeld N, Silva C, Keefe D. Estrogen modifies the temperature effects of progesterone. J Appl Physiol (1985). 2000;88:1643-9 pubmed
    ..These data are also consistent with previous findings that estrogen lowers the thermoregulatory operating point...
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    Stachenfeld N, Silva C, Keefe D, Kokoszka C, Nadel E. Effects of oral contraceptives on body fluid regulation. J Appl Physiol (1985). 1999;87:1016-25 pubmed
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    Stachenfeld N, Keefe D, Palter S. Estrogen and progesterone effects on transcapillary fluid dynamics. Am J Physiol Regul Integr Comp Physiol. 2001;281:R1319-29 pubmed
    ..05), and the PV loss during ANP infusion was attenuated (-0.9 +/- 0.2 and -0.2 +/- 0.2 ml/kg for GnRH analog-alone and E(2)-P(4) treatments, respectively). Thus the E(2)-P(4) treatment lowered CFC and reduced PV loss during ANP infusion...
  9. Turner J, Marsteller D, Luxkaranayagam A, Fletcher J, Stachenfeld N. Mild exercise in female subjects impairs complex learning independent of hydration status and emotion. Physiol Behav. 2017;180:113-119 pubmed publisher
    ..A bout of mild aerobic exercise compromised performance on a complex learning and memory task, but this change was unaffected by hydration status or emotion. ..

More Information


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    Stachenfeld N, Splenser A, Calzone W, Taylor M, Keefe D. Sex differences in osmotic regulation of AVP and renal sodium handling. J Appl Physiol (1985). 2001;91:1893-901 pubmed
    ..In men, this greater sensitivity was associated with an increase in systolic blood pressure and pulse pressure during HSI, most likely due to a shift in the pressure-natriuresis curve...