Research Topics
Genomes and Genes | G L SnyderSummaryAffiliation: The Rockefeller University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivoG L Snyder
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
J Neurosci 20:4480-8. 2000..These results identify DARPP-32 and AMPA-type glutamate receptors as likely essential cellular effectors for psychostimulant actions...
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5J A Bibb
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021 6399, USA
J Biol Chem 276:14490-7. 2001....
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5J A Bibb
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
Nature 410:376-80. 2001..Our results suggest that changes in Cdk5 levels mediated by DeltaFosB, and resulting alterations in signalling involving D1 dopamine receptors, contribute to adaptive changes in the brain related to cocaine addiction...
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease miceJ A Bibb
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 97:6809-14. 2000..HD mice also show defects in dopamine-regulated ion channels and in the D(1) dopamine/DARPP-32 signaling cascade. These presymptomatic defects may contribute to HD pathology...
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal gangliaG L Caporaso
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Neuropharmacology 39:1637-44. 2000..We speculate that ARPP-21 might mediate some of the physiologic effects of dopamine and certain drugs of abuse in the basal ganglia...
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteinsI Dulubova
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York 10021, USA
J Neurochem 77:229-38. 2001..The conservation of this protein family through evolution suggests that it subserves an important cellular function that is regulated by PKA...
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neuronsJ A Bibb
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
Nature 402:669-71. 1999..Thus DARPP-32 is a bifunctional signal transduction molecule which, by distinct mechanisms, controls a serine/threonine kinase and a serine/threonine phosphatase...
DARPP-32: regulator of the efficacy of dopaminergic neurotransmissionA A Fienberg
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
Science 281:838-42. 1998..The results show that DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission...
