R S Smith
Affiliation: The Jackson Laboratory
- Anderson M, Libby R, Mao M, Cosma I, Wilson L, Smith R, et al. Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma. BMC Biol. 2006;4:20 pubmed..These new congenic strains provide a valuable new resource for further studying the genetic and mechanistic complexity of this form of glaucoma. ..
- Smith R, John S, Zabeleta A, Davisson M, Hawes N, Chang B. The bst locus on mouse chromosome 16 is associated with age-related subretinal neovascularization. Proc Natl Acad Sci U S A. 2000;97:2191-5 pubmed..This represents a spontaneous, genetically determined model of SRN. Bst/+ mice offer the possibility of exploring the molecular mechanisms of SRN without the need for exogenous agents. ..
- Smith R, Hawes N, Chang B, Roderick T, Akeson E, Heckenlively J, et al. Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract. Genomics. 2000;63:314-20 pubmed..It is predicted that the defective gene product alters protein folding of the gamma-crystallin(s) and results in lens opacity. ..