Craig J Slawecki

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi request reprint Two-choice reaction time performance in Sprague-Dawley rats exposed to alcohol during adolescence or adulthood
    Craig J Slawecki
    Molecular and Integrative Neuroscience Department, The Scripps Research Institute, La Jolla, California 92037, USA
    Behav Pharmacol 17:605-14. 2006
  2. ncbi request reprint Neurobehavioral profiles during the acute phase of ethanol withdrawal in adolescent and adult Sprague-Dawley rats
    Craig J Slawecki
    The Scripps Research Institute, Molecular and Integrative Neuroscience Department, La Jolla, CA 92037, USA
    Behav Brain Res 170:41-51. 2006
  3. ncbi request reprint Effects of neuropeptide Y on appetitive and consummatory behaviors associated with alcohol drinking in wistar rats with a history of ethanol exposure
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 29:584-90. 2005
  4. ncbi request reprint The effects of social isolation on neuropeptide Y levels, exploratory and anxiety-related behaviors in rats
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology CVN 14, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Pharmacol Biochem Behav 83:28-34. 2006
  5. ncbi request reprint Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology, Mail Drop CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Behav Brain Res 161:133-40. 2005
  6. ncbi request reprint Long-term neurobehavioral effects of alcohol or nicotine exposure in adolescent animal models
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CVN14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Ann N Y Acad Sci 1021:448-52. 2004
  7. ncbi request reprint Increased alcohol drinking in isolate-housed alcohol-preferring rats
    Cindy L Ehlers
    Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA
    Behav Neurosci 121:111-9. 2007
  8. ncbi request reprint Increased anxiety-like behavior in adult rats exposed to nicotine as adolescents
    Craig J Slawecki
    Department of Neuropharmacology, CVN 14, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Pharmacol Biochem Behav 75:355-61. 2003
  9. ncbi request reprint Antagonism of neuropeptide YY1 receptors does not inhibit ethanol's effects on cortical EEG and ERPs in Wistar rats
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CFN 14, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    J Stud Alcohol 66:559-66. 2005
  10. ncbi request reprint Enhanced prepulse inhibition following adolescent ethanol exposure in Sprague-Dawley rats
    Craig J Slawecki
    Scripps Research Institute, Department of Neuropharmacology, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 29:1829-36. 2005

Detail Information

Publications27

  1. ncbi request reprint Two-choice reaction time performance in Sprague-Dawley rats exposed to alcohol during adolescence or adulthood
    Craig J Slawecki
    Molecular and Integrative Neuroscience Department, The Scripps Research Institute, La Jolla, California 92037, USA
    Behav Pharmacol 17:605-14. 2006
    ....
  2. ncbi request reprint Neurobehavioral profiles during the acute phase of ethanol withdrawal in adolescent and adult Sprague-Dawley rats
    Craig J Slawecki
    The Scripps Research Institute, Molecular and Integrative Neuroscience Department, La Jolla, CA 92037, USA
    Behav Brain Res 170:41-51. 2006
    ..Adolescent and adult rats show differential sensitivity to many of the effects of ethanol...
  3. ncbi request reprint Effects of neuropeptide Y on appetitive and consummatory behaviors associated with alcohol drinking in wistar rats with a history of ethanol exposure
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 29:584-90. 2005
    ..The current study was designed to determine whether NPY differentially alters ethanol-associated appetitive behavior (i.e., lever pressing) or ethanol consumption in Wistar rats with a history of ethanol vapor exposure...
  4. ncbi request reprint The effects of social isolation on neuropeptide Y levels, exploratory and anxiety-related behaviors in rats
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology CVN 14, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Pharmacol Biochem Behav 83:28-34. 2006
    ....
  5. ncbi request reprint Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology, Mail Drop CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Behav Brain Res 161:133-40. 2005
    ..Furthermore, the results presented here suggest that a balance between the stress-related peptides NPY and CRF may be involved in the regulation of ethanol intake...
  6. ncbi request reprint Long-term neurobehavioral effects of alcohol or nicotine exposure in adolescent animal models
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CVN14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Ann N Y Acad Sci 1021:448-52. 2004
    ..These findings support the hypothesis that adolescents are uniquely susceptible to the effects of chronic alcohol and nicotine exposure...
  7. ncbi request reprint Increased alcohol drinking in isolate-housed alcohol-preferring rats
    Cindy L Ehlers
    Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA
    Behav Neurosci 121:111-9. 2007
    ..Selective enhancement of limited access ethanol drinking in P rats may represent a model whereby genetic liability to excessive drinking is enhanced by specific environmental exposures...
  8. ncbi request reprint Increased anxiety-like behavior in adult rats exposed to nicotine as adolescents
    Craig J Slawecki
    Department of Neuropharmacology, CVN 14, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Pharmacol Biochem Behav 75:355-61. 2003
    ..The purpose of this study was to further define the behavioral effects of nicotine exposure during adolescence...
  9. ncbi request reprint Antagonism of neuropeptide YY1 receptors does not inhibit ethanol's effects on cortical EEG and ERPs in Wistar rats
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CFN 14, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    J Stud Alcohol 66:559-66. 2005
    ..In the present study, the NPY Y1 receptor antagonist BIBP3226 was administered alone or in combination with a moderate dose of ethanol to determine whether it interacted with the neurobehavioral effects of ethanol...
  10. ncbi request reprint Enhanced prepulse inhibition following adolescent ethanol exposure in Sprague-Dawley rats
    Craig J Slawecki
    Scripps Research Institute, Department of Neuropharmacology, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 29:1829-36. 2005
    ..Six days after the cessation of ethanol vapor exposure, the ASR and PPI were assessed...
  11. ncbi request reprint Increased CRF-like and NPY-like immunoreactivity in adult rats exposed to nicotine during adolescence: relation to anxiety-like and depressive-like behavior
    Craig J Slawecki
    Department of Neuropharmacology, CVN 14, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Neuropeptides 39:369-77. 2005
    ..This study further examined the impact of adolescent nicotine exposure on anxiety-like and depressive-like behavior, as well as on levels of corticotropin-releasing factor (CRF) and neuropeptide Y (NPY) in this model...
  12. ncbi request reprint EEG and ERP profiles in the high alcohol preferring (HAP) and low alcohol preferring (LAP) mice: relationship to ethanol preference
    Craig J Slawecki
    Department of Neuropharmacology, The Scripps Research Institute, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Brain Res 961:243-54. 2003
    ..Decreased P3 latency in LAPs compared to HAPs and HS/Ibgs mice may be a 'protective factor'...
  13. ncbi request reprint Effect of ethanol on brain neuropeptides in adolescent and adult rats
    Craig J Slawecki
    Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 N Torrey Pines Road, La Jolla, California 92307, USA
    J Stud Alcohol 66:46-52. 2005
    ..This study assessed the effects of ethanol exposure on several neuropeptides to begin to elucidate potential substrates that could mediate the differential effects of ethanol on adolescent and adult rats...
  14. ncbi request reprint The effects of corticotropin-releasing factor on the cortical EEG are reduced following adolescent nicotine exposure
    Craig J Slawecki
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Neuropeptides 37:66-73. 2003
    ..Given the role of CRF systems in behavioral responses to stress and anxiety, these data suggest that adolescent nicotine exposure may produce long-term decreases in neurophysiological responses to stress...
  15. ncbi request reprint Effect of social isolation on ethanol consumption and substance P/neurokinin expression in Wistar rats
    Annika Thorsell
    The Scripps Research Institute, Department of Neuropharmacology CVN 14, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Alcohol 36:91-7. 2005
    ..These data indicate that endogenous SP and neurokinin levels are reduced by isolation housing, but this was not associated with alterations in drinking levels using a two-bottle choice procedure...
  16. ncbi request reprint Comparison of anxiety-like behavior in adolescent and adult Sprague-Dawley rats
    Craig J Slawecki
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Behav Neurosci 119:1477-83. 2005
    ..These studies demonstrate that adolescents display increased anxiety-like behavior when test conditions are more aversive and following exposure to stress...
  17. ncbi request reprint Comparison of the onset of hypoactivity and anxiety-like behavior during alcohol withdrawal in adolescent and adult rats
    Craig J Slawecki
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 28:598-607. 2004
    ..The objective of these studies was to compare the appearance of ethanol withdrawal-related behaviors in adolescent and adult rats...
  18. ncbi request reprint Neurophysiologic consequences of neonatal ethanol exposure in the rat
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Alcohol 34:187-96. 2004
    ..This neurobehavioral profile in the rat is consistent with clinical observations of attention deficits and hyperactivity in children exposed to ethanol during prenatal development...
  19. ncbi request reprint Assessment of sustained attention in ad libitum fed Wistar rats: effects of MK-801
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Physiol Behav 85:346-53. 2005
    ..However, evidence indicates that dietary restriction can have profound effects on brain function and on the neurobehavioral effects of drugs...
  20. ncbi request reprint Electrophysiological effects of allopregnanolone in rats with a history of ethanol exposure
    Craig J Slawecki
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 29:66-74. 2005
    ..The purpose of this study was to examine the neurophysiological effects of ALLO in rats with a history of chronic EtOH exposure after a protracted period of abstinence...
  21. ncbi request reprint Neurokinin type-3 receptor stimulation impairs ethanol-associated appetitive behavior in Wistar rats
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, La Jolla, CA 92037, USA
    Alcohol Clin Exp Res 27:1962-70. 2003
    ..In a follow-up study, senktide's effects on ethanol self-administration after intracerebroventricular (ICV) infusion were examined...
  22. ncbi request reprint Neuropeptide Y administration into the amygdala does not affect ethanol consumption
    Simon N Katner
    The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Alcohol 28:29-38. 2002
    ..Overall, these findings support the suggestion that NPY administration into the central nucleus of the amygdala does not alter consumption of 10 E, 2S, or food, nor the cortical electroencephalographic or locomotor activity...
  23. ncbi request reprint Event-related potential responses to alcohol-related stimuli in African-American young adults: relation to family history of alcoholism and drug usage
    Cindy L Ehlers
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Alcohol Alcohol 38:332-8. 2003
    ..To use event-related potentials (ERPs) to investigate the response to alcohol-related stimuli in African-American young adults...
  24. ncbi request reprint Lasting effects of adolescent nicotine exposure on the electroencephalogram, event related potentials, and locomotor activity in the rat
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Brain Res Dev Brain Res 138:15-25. 2002
    ..These changes may be indicative of a lasting 'nicotine abstinence syndrome' characterized by increased arousal, anxiety, or emotionality...
  25. ncbi request reprint Altered EEG responses to ethanol in adult rats exposed to ethanol during adolescence
    Craig J Slawecki
    Scripps Research Institute, Department of Neuropharmacology, La Jolla, California 92037, USA
    Alcohol Clin Exp Res 26:246-54. 2002
    ..This study was designed to assess long-term changes in EEG activity after EtOH challenge in adult rats exposed to EtOH during adolescence...
  26. ncbi request reprint Effects of adolescent ethanol exposure on ethanol consumption in adult rats
    Craig J Slawecki
    The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Alcohol 26:23-30. 2002
    ..Overall, these findings indicate that forced exposure to ethanol vapor during adolescence does not seem to be sufficient to alter initiation or maintenance of limited-access ethanol self-administration...
  27. ncbi request reprint Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506 0044, USA
    Alcohol Clin Exp Res 29:1720-5. 2005
    ..Finally, Linda Spear provided some summary points and recommendations regarding unresolved issues and future directions...