Jonathan Slaughter

Summary

Affiliation: Nationwide Childrens Hospital/The Ohio State University
Location: Columbus, OH, USA
URL: http://www.nationwidechildrens.org/jonathan-l-slaughter
Summary:
My research goal is to improve neonatal care through rigorous comparative effectiveness research that will evaluate the risks and benefits of medications that, despite limited evidence, are commonly used in the treatment of prematurity-related disorders. Such medications include diuretics, acid suppressants, antiepileptics, inhaled steroids, bronchodilators, and non-steroidal anti-inflammatory drugs (NSAIDs). It is currently estimated that up to ninety percent of neonatal medication use is unapproved or off-label, and clinicians caring for infants must depend upon potentially dangerous extrapolations of adult trial findings. My patient-centered research aims to improve the outcomes of preterm infants by informing clinical practice decisions regarding medication administration.

Publications

  1. doi request reprint False-negative results of pre-discharge neonatal bilirubin screening to predict severe hyperbilirubinemia: a need for caution
    Jonathan Slaughter
    Cincinnati Children s Hospital, Cincinnati, OH 45229, USA
    Eur J Pediatr 168:1461-6. 2009
  2. doi request reprint Utilization of blood spot testing for metabolic-genetic disorders in Honduras: is it time for newborn screening?
    Jonathan L Slaughter
    Division of Neonatology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Child Neurol 25:306-11. 2010
  3. doi request reprint The effects of gestational age and birth weight on false-positive newborn-screening rates
    Jonathan L Slaughter
    Cincinnati Children s Hospital Medical Center, Division of Neonatology, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Pediatrics 126:910-6. 2010
  4. doi request reprint Echocardiographic detection of pulmonary hypertension in extremely low birth weight infants with bronchopulmonary dysplasia requiring prolonged positive pressure ventilation
    J L Slaughter
    The Perinatal Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Perinatol 31:635-40. 2011
  5. pmc Hospital variation in nitric oxide use for premature infants
    Michael R Stenger
    Department of Pediatrics, The Ohio State University College of Medicine and Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Pediatrics 129:e945-51. 2012
  6. pmc Pharmacological treatment of neonatal seizures: a systematic review
    Laurel A Slaughter
    Division of Child Neurology, Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Child Neurol 28:351-64. 2013
  7. pmc Variation in the use of diuretic therapy for infants with bronchopulmonary dysplasia
    Jonathan L Slaughter
    Department of Pediatrics, The Ohio State University College of Medicine and Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Pediatrics 131:716-23. 2013

Detail Information

Publications7

  1. doi request reprint False-negative results of pre-discharge neonatal bilirubin screening to predict severe hyperbilirubinemia: a need for caution
    Jonathan Slaughter
    Cincinnati Children s Hospital, Cincinnati, OH 45229, USA
    Eur J Pediatr 168:1461-6. 2009
    ..Universal early post-discharge follow-up should remain the cornerstone of preventing severe hyperbilirubinemia...
  2. doi request reprint Utilization of blood spot testing for metabolic-genetic disorders in Honduras: is it time for newborn screening?
    Jonathan L Slaughter
    Division of Neonatology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Child Neurol 25:306-11. 2010
    ..The study findings indicate that collaborative blood spot testing aids in the diagnosis of Honduran metabolic-genetic disease. Newborn screening is now needed to diagnose and treat these diseases before morbidity/mortality develops...
  3. doi request reprint The effects of gestational age and birth weight on false-positive newborn-screening rates
    Jonathan L Slaughter
    Cincinnati Children s Hospital Medical Center, Division of Neonatology, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Pediatrics 126:910-6. 2010
    ..The objective of this study was to determine variation in newborn screening FPRs according to birth weight and gestational age. Our secondary objective was to examine the effect of postnatal age on FPRs in preterm infants...
  4. doi request reprint Echocardiographic detection of pulmonary hypertension in extremely low birth weight infants with bronchopulmonary dysplasia requiring prolonged positive pressure ventilation
    J L Slaughter
    The Perinatal Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Perinatol 31:635-40. 2011
    ....
  5. pmc Hospital variation in nitric oxide use for premature infants
    Michael R Stenger
    Department of Pediatrics, The Ohio State University College of Medicine and Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Pediatrics 129:e945-51. 2012
    ..To describe inter-center hospital variation in inhaled nitric oxide (iNO) administration to infants born prior to 34 weeks' gestation at US children's hospitals...
  6. pmc Pharmacological treatment of neonatal seizures: a systematic review
    Laurel A Slaughter
    Division of Child Neurology, Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Child Neurol 28:351-64. 2013
    ..These findings have the potential to serve as a clinical reference and to inform the design of comparative effectiveness investigations for neonatal antiepileptics...
  7. pmc Variation in the use of diuretic therapy for infants with bronchopulmonary dysplasia
    Jonathan L Slaughter
    Department of Pediatrics, The Ohio State University College of Medicine and Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Pediatrics 131:716-23. 2013
    ....