Research Topics
| JEFFREY SILBERSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
Research Grants
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Detail Information
Publications
Assessment of surfactant use in preterm infants as a marker of neonatal intensive care unit qualityHeather C Kaplan
Perinatal Institute and James M, Anderson Center for Health Systems Excellence, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, USA
BMC Health Serv Res 11:22. 2011..However, process measures have remained largely unexamined. The objective of this research was to examine variation in surfactant use as a possible process measure of neonatal quality...- Does ovarian cancer treatment and survival differ by the specialty providing chemotherapy?Jeffrey H Silber
The Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Clin Oncol 25:1169-75. 2007..We asked whether survival, treatment, and toxicity differed according to the type of specialist providing the chemotherapy after surgery... - Influence of patient and hospital characteristics on anesthesia time in medicare patients undergoing general and orthopedic surgeryJeffrey H Silber
The Center for Outcomes Research, The Children s Hospital of Philadelphia, PA 19104, USA
Anesthesiology 106:356-64. 2007..Norms for procedure length have not been reported from Medicare data sets, nor has the influence of patient and hospital characteristics on procedure time been estimated using Medicare data... - Estimating anesthesia and surgical procedure times from medicare anesthesia claimsJeffrey H Silber
The Center for Outcomes Research, The Children s Hospital of Philadelphia, PA 19104, USA
Anesthesiology 106:346-55. 2007..However, due to the need for costly chart review, most studies are limited to single-institution analyses. In this article, the authors describe how well the anesthesia claim from Medicare can estimate chart times... - Failure-to-rescue: comparing definitions to measure quality of careJeffrey H Silber
Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Med Care 45:918-25. 2007..This study examines the reliability and validity of different FTR measures currently in use... - Can dexrazoxane reduce myocardial injury in anthracycline-treated children with acute lymphoblastic leukemia?Jeffrey H Silber
Center for Outcomes Research, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Nat Clin Pract Oncol 1:16-7. 2004 - Role of afterload reduction in the prevention of late anthracycline cardiomyopathyJeffrey H Silber
Division of Pediatric Oncology, Department of Pediatrics, Center for Outcomes Research, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Pediatr Blood Cancer 44:607-13. 2005.... - Design and baseline characteristics for the ACE Inhibitor After Anthracycline (AAA) study of cardiac dysfunction in long-term pediatric cancer survivorsJ H Silber
Division of Pediatric Oncology, Department of Pediatrics, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Am Heart J 142:577-85. 2001.... - Enalapril to prevent cardiac function decline in long-term survivors of pediatric cancer exposed to anthracyclinesJeffrey H Silber
Center for Outcomes Research, Children s Hospital of Philadelphia, 3535 Market St, Suite 1029, Philadelphia, PA 19104, USA
J Clin Oncol 22:820-8. 2004.... - Female gender increases the risk of death during hospitalization for pediatric cardiac surgeryHarry A Seifert
Department of Anesthesiology and Critical Care, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Thorac Cardiovasc Surg 133:668-75. 2007..Secondary objectives were to determine other factors associated with increased risk of death and whether female gender is associated with increased length of stay or total charges... - Preoperative antibiotics and mortality in the elderlyJeffrey H Silber
Center for Outcomes Research, Children s Hospital of Philadelphia, Philadelphia, PA, USA
Ann Surg 242:107-14. 2005..The objective of this study was to determine whether preoperative antibiotics are associated with a reduced risk of death... - Length of stay, conditional length of stay, and prolonged stay in pediatric asthmaJeffrey H Silber
The Center for Outcomes Research, The Children's Hospital of Philadelphia, PA 19104, USA
Health Serv Res 38:867-86. 2003..We conclude that policy initiatives in New York, and other states, should focus their efforts on improving the care provided to less severe patients in order to help reduce overall length of stay... - Variation in chemotherapy utilization in ovarian cancer: the relative contribution of geographyDaniel Polsky
Division of General Internal Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Health Serv Res 41:2201-18. 2006..Our finding that density of oncology hospitals predicts chemotherapy use suggests that provider supply is positively correlated with geographic variation... - The Hospital Compare mortality model and the volume-outcome relationshipJeffrey H Silber
Center for Outcomes Research, 3535 Market Street, Suite 1029, Philadelphia, PA 19104, USA
Health Serv Res 45:1148-67. 2010..We ask whether Medicare's Hospital Compare random effects model correctly assesses acute myocardial infarction (AMI) hospital mortality rates when there is a volume-outcome relationship... - Nonoperative care for hip fracture in the elderly: the influence of race, income, and comorbiditiesMark D Neuman
Robert Wood Johnson Foundation Clinical Scholars Program, University of Pennsylvania, Philadelphia, PA, USA
Med Care 48:314-20. 2010..Operative repair is the standard of care, maximizing the chances of functional recovery. Not receiving operative care may condemn patients to a lifetime of pain and potential immobility... - Aggressive treatment style and surgical outcomesJeffrey H Silber
Center for Outcomes Research, The Children s Hospital of Philadelphia, 3535 Market Street, Suite 1029, Philadelphia, PA 19104, USA
Health Serv Res 45:1872-92. 2010..We aimed to determine the association between aggressive treatment style and surgical outcomes... - Hospital nurse staffing and patient mortality, nurse burnout, and job dissatisfactionLinda H Aiken
Center for Health Outcomes and Policy Research, School of Nursing, University of Pennsylvania, 420 Guardian Dr, Philadelphia, PA 19104 6096, USA
JAMA 288:1987-93. 2002.... - Anesthesiologist board certification and patient outcomesJeffrey H Silber
Center for Outcomes Research, Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Pennsylvania 19094, USA
Anesthesiology 96:1044-52. 2002..The aim of this study was to compare the outcomes of patients who underwent surgical procedures under the care of an anesthesiologist with or without board certification... - Time under: hospital and patient characteristics affecting anesthesia durationJeffrey H Silber
Leonard Davis Institute of Health Economics, The University of Pennsylvania, and Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
LDI Issue Brief 12:1-4. 2007.... - Racial differences in the use of respiratory medications in premature infants after discharge from the neonatal intensive care unitScott A Lorch
Department of Pediatrics, Division of Neonatology, University of Pennsylvania, Philadelphia, PA, USA
J Pediatr 151:604-10, 610.e1. 2007.... - Impact of admission-day crowding on the length of stay of pediatric hospitalizationsScott A Lorch
Division of Neonatology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Pediatrics 121:e718-30. 2008..There is little information about the impact of admission-day crowding on the outcome of children who are hospitalized with common pediatric conditions... - Use of prolonged travel to improve pediatric risk-adjustment modelsScott A Lorch
Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Health Serv Res 44:519-41. 2009..To determine whether travel variables could explain previously reported differences in lengths of stay (LOS), readmission, or death at children's hospitals versus other hospital types... - Hospital teaching intensity, patient race, and surgical outcomesJeffrey H Silber
Center for Outcomes Research, The Children s Hospital of Philadelphia, 3535 Market St, Ste 1029, Philadelphia, PA 19104, USA
Arch Surg 144:113-20; discussion 121. 2009.... - Antibiotic use in premature infants after discharge from the neonatal intensive care unitScott A Lorch
Center for Outcomes Research, The Children s Hospital of Philadelphia, 3535 Market Street, Philadelphia, PA 19104, USA
Clin Pediatr (Phila) 49:249-57. 2010..Even in a high-risk population of children, factors other than the medical history and presentation of the child may alter antibiotic prescription patterns and result in variations in care... - The role of outpatient facilities in explaining variations in risk-adjusted readmission rates between hospitalsScott A Lorch
Department of Pediatrics, Center for Outcomes Research, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Health Serv Res 45:24-41. 2010..Validate risk-adjusted readmission rates as a measure of inpatient quality of care after accounting for outpatient facilities, using premature infants as a test case... - Optimal multivariate matching before randomizationRobert Greevy
Department of Statistics, The Wharton School, University of Pennsylvania, 400 Jon M. Huntsman Hall, 3730 Walnut Street, Philadelphia, PA 19104-6340, USA
Biostatistics 5:263-75. 2004..Unmatched randomizations experienced rare disasters which were consistently avoided by matched randomizations... - Using health-related quality of life measures to predict cardiac function in survivors exposed to anthracyclinesJill P Ginsberg
Department of Pediatrics, Center for Outcomes Research, The Children's Hospital of Philadelphia, 3535 Market St, Suite 1029, Philadelphia, PA 19104, USA
J Clin Oncol 22:3149-55. 2004..Patient history appears to be no substitute for cardiac testing in this cohort... - Equivalent lengths of stay of pediatric patients hospitalized in rural and nonrural hospitalsScott A Lorch
Center for Outcomes Research, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Pediatrics 114:e400-8. 2004.... - Identifying factors predicting immunization delay for children followed in an urban primary care network using an electronic health recordAlexander G Fiks
Pediatric Research Consortium, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatrics 118:e1680-6. 2006..The objective of this study was to use data entered at the point of care within an electronic health record to identify factors that predispose children in an inner-city population to immunization delay... - Time to send the preemie home? Additional maturity at discharge and subsequent health care costs and outcomesJeffrey H Silber
Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Health Serv Res 44:444-63. 2009..To determine whether longer stays of premature infants allowing for increased physical maturity result in subsequent postdischarge cost savings that help counterbalance increased inpatient costs... - Mortality among hospitalized Medicare beneficiaries in the first 2 years following ACGME resident duty hour reformKevin G Volpp
Center for Health Equity Research and Promotion, Veterans Administration Hospital, Philadelphia, Pennsylvania 19104 6021, USA
JAMA 298:975-83. 2007..The association of duty hour reform with mortality among patients in teaching hospitals nationally has not been well established... - Prolonged hospital stay and the resident duty hour rules of 2003Jeffrey H Silber
Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Med Care 47:1191-200. 2009..Resident duty hour reforms of 2003 had the potential to create a major impact on the delivery of inpatient care... - Changes in prognosis after the first postoperative complicationJeffrey H Silber
The Center for Outcomes Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Med Care 43:122-31. 2005..Postoperative complications are common in the Medicare population, yet no study has formally quantified the change in prognosis that occurs after a broad range of first complications... - Did duty hour reform lead to better outcomes among the highest risk patients?Kevin G Volpp
Center for Health Equity Research and Promotion, Veterans Administration Hospital, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
J Gen Intern Med 24:1149-55. 2009..Earlier work demonstrated that ACGME duty hour reform did not adversely affect mortality, with slight improvement noted among specific subgroups... - Hospital nurse staffing, education, and patient mortalityLinda H Aiken
Leonard Davis Institute of Health Economics, University of Pennsylvania, 3641 Locust Walk, Philadelphia, PA, 19104-6218, USA
LDI Issue Brief 9:1-4. 2003.... - Effect of work-hours regulations on intensive care unit mortality in United States teaching hospitalsMeeta Prasad
Division of Pulmonary, Allergy, and Critical Care Medicine MP, JDC, JMK, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Crit Care Med 37:2564-9. 2009..The United States instituted restrictions on resident work-hours in July 2003. The clinical impact of this reform on critically ill patients is unknown... - Mortality among patients in VA hospitals in the first 2 years following ACGME resident duty hour reformKevin G Volpp
Center for Health Equity Research and Promotion, Veterans Administration Hospital, Philadelphia, Pennsylvania 19104 6021, USA
JAMA 298:984-92. 2007..The association of these changes with mortality among hospitalized patients has not been well established... - Using automated clinical data for risk adjustment: development and validation of six disease-specific mortality predictive models for pay-for-performanceYing P Tabak
Department of Clinical Research, Cardinal Health s MediQual Business, Marlborough, MA 01752, USA
Med Care 45:789-805. 2007..We also evaluated the additional value of vital signs and altered mental status (Full Models)... - Should Do-Not-Resuscitate status be included as a mortality risk adjustor? The impact of DNR variations on performance reportingYing P Tabak
Department of Research, Cardinal Health Data and Clinical Information MediQual, Marlborough, Massachusetts 01752, USA
Med Care 43:658-66. 2005..The practice of ordering "Do-Not-Resuscitate" (DNR) varies across hospitals. No research has explored how the DNR variation would affect cross-institutional performance reporting when DNR status is used as a risk adjustor... - Do regulations limiting residents' work hours affect patient mortality?David L Howard
Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Gen Intern Med 19:1-7. 2004.... - Hospital nurse practice environments and outcomes for surgical oncology patientsChristopher R Friese
Dana Farber Cancer Institute, Harvard School of Public Health, 44 Binney Street SM 271, Boston, MA 02115, USA
Health Serv Res 43:1145-63. 2008..To examine the effect of nursing practice environments on outcomes of hospitalized cancer patients undergoing surgery... - Response to Letter From Joseph P. Parker, PhDYing Tabak
Med Care 43:1160; author reply 1160. 2005 - Educational levels of hospital nurses and surgical patient mortalityLinda H Aiken
Center for Health Outcomes and Policy Research, School of Nursing, University of Pennsylvania, Philadelphia 19104 6096, USA
JAMA 290:1617-23. 2003..Growing evidence suggests that nurse staffing affects the quality of care in hospitals, but little is known about whether the educational composition of registered nurses (RNs) in hospitals is related to patient outcomes... - Market reform in New Jersey and the effect on mortality from acute myocardial infarctionKevin G M Volpp
Center for Health Equity Research and Promotion, Philadelphia Veterans Hospital, and University of Pennsylvania School of Medicine, 19104-6021, USA
Health Serv Res 38:515-33. 2003..A relative decrease in the use of cardiac procedures in New Jersey may partly explain this finding. Additional studies should be done to identify whether other market reforms have been associated with changes in the quality of care... - Weekend admission for myocardial infarctionJeffrey H Silber
N Engl J Med 357:85-6; author reply 87-8. 2007 - Medicare claims and anesthesia clinical research: a perfect matchJeffrey H Silber
Reg Anesth Pain Med 28:259-61. 2003
Research Grants
- Improving Process MeasurementJeffrey H Silber; Fiscal Year: 2010..If successful, results from this application could be utilized to implement template matching when assessing process compliance for Hospital Compare and other programs which study process as a quality of care indicator. ..
- Describing and Understanding Racial DisparitiesJeffrey H Silber; Fiscal Year: 2010....
- Understanding Racial Disparities in Surgical OutcomesJeffrey H Silber; Fiscal Year: 2010..abstract_text> ..
- Obesity and Surgical OutcomesJeffrey H Silber; Fiscal Year: 2010..The multi-institutional OBSOS study will examine differences in outcomes and treatments between obese and normal weight patients, and in so doing, should make important contributions to the care of these patients. ..
- Describing and Understanding Racial DisparitiesJEFFREY SILBER; Fiscal Year: 2009....
- Understanding Racial Disparities in Surgical OutcomesJEFFREY SILBER; Fiscal Year: 2009..This project aims to understand this disparity between minority and white Americans undergoing surgery through studying disparities in procedure time. ..
- Obesity and Surgical OutcomesJEFFREY SILBER; Fiscal Year: 2009..The multi-institutional OBSOS study will examine differences in outcomes and treatments between obese and normal weight patients, and in so doing, should make important contributions to the care of these patients. ..
- Obesity and Surgical OutcomesJEFFREY SILBER; Fiscal Year: 2007..The multi-institutional OBSOS study will examine differences in outcomes and treatments between obese and normal weight patients, and in so doing, should make important contributions to the care of these patients. ..
- Provider Specialty and Outcomes in Ovarian CancerJEFFREY SILBER; Fiscal Year: 2003..Our hope is that this study could serve as a model for other matched cohort studies involving chart review utilizing the SEER-Medicare database. ..
- CONDITIONAL LENGTH OF STAY: A PEDIATRICS OUTCOME MEASUREJEFFREY SILBER; Fiscal Year: 2001..Finally, (5) policy recommendations and guidelines for the use of CLOS to measure pediatric quality of care will be developed. ..
- Obesity and Surgical OutcomesJeffrey H Silber; Fiscal Year: 2010..The multi-institutional OBSOS study will examine differences in outcomes and treatments between obese and normal weight patients, and in so doing, should make important contributions to the care of these patients. ..