Steven S Shen

Summary

Affiliation: The Methodist Hospital
Country: USA

Publications

  1. doi request reprint Use of frozen section in genitourinary pathology
    Steven S Shen
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas 77030, USA
    Pathology 44:427-33. 2012
  2. doi request reprint Role of immunohistochemistry in diagnosing renal neoplasms: when is it really useful?
    Steven S Shen
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas 77030, USA
    Arch Pathol Lab Med 136:410-7. 2012
  3. doi request reprint Number of lymph nodes examined and associated clinicopathologic factors in colorectal carcinoma
    Steven S Shen
    Department of Pathology, The Methodist Hospital and Research Institute, Weill Medical College of Cornell University, Houston, Texas 77030, USA
    Arch Pathol Lab Med 133:781-6. 2009
  4. doi request reprint Synchronous renal and adrenal masses: an analysis of 80 cases
    Armita Bahrami
    Baylor College of Medicine, Houston, TX, USA
    Ann Diagn Pathol 13:9-15. 2009
  5. ncbi request reprint Mucinous tubular and spindle cell carcinoma of kidney is probably a variant of papillary renal cell carcinoma with spindle cell features
    Steven S Shen
    Department of Pathology, The Methodist Hospital and Research Institute, Houston, TX 77030, USA
    Ann Diagn Pathol 11:13-21. 2007
  6. doi request reprint PAX-2 is a helpful marker for diagnosing metastatic renal cell carcinoma: comparison with the renal cell carcinoma marker antigen and kidney-specific cadherin
    Ayhan Ozcan
    Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Arch Pathol Lab Med 134:1121-9. 2010
  7. doi request reprint Reappraisal of T3N0/NxM0 renal cell carcinoma: significance of extent of fat invasion, renal vein invasion, and adrenal invasion
    Soo Jin Jung
    Department of Pathology, The Methodist Hospital and Research Institute, and Weill Medical College of Cornell University, Houston, TX 77030, USA
    Hum Pathol 39:1689-94. 2008
  8. doi request reprint PAX-2 expression in non-neoplastic, primary neoplastic, and metastatic neoplastic tissue: A comprehensive immunohistochemical study
    Qihui Jim Zhai
    Departments of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Appl Immunohistochem Mol Morphol 18:323-32. 2010
  9. ncbi request reprint Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma
    Victor G Prieto
    Department of Pathology, The University of Texas M D Anderson Cancer Center, The Methodist Hospital, Houston 77030, USA
    Clin Cancer Res 12:6709-15. 2006
  10. doi request reprint Muscularis mucosae versus muscularis propria in gallbladder, cystic duct, and common bile duct: smoothelin and desmin immunohistochemical study
    Kirtee Raparia
    Department of Pathology, The Methodist Hospital, Weill Medical College, Cornell University, Houston, TX 77030, USA
    Ann Diagn Pathol 14:408-12. 2010

Collaborators

Detail Information

Publications46

  1. doi request reprint Use of frozen section in genitourinary pathology
    Steven S Shen
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas 77030, USA
    Pathology 44:427-33. 2012
    ....
  2. doi request reprint Role of immunohistochemistry in diagnosing renal neoplasms: when is it really useful?
    Steven S Shen
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas 77030, USA
    Arch Pathol Lab Med 136:410-7. 2012
    ..The number of useful markers in our routine practice continues to increase. The challenge will be to choose among them and to decide in which situations immunohistochemistry will be truly useful...
  3. doi request reprint Number of lymph nodes examined and associated clinicopathologic factors in colorectal carcinoma
    Steven S Shen
    Department of Pathology, The Methodist Hospital and Research Institute, Weill Medical College of Cornell University, Houston, Texas 77030, USA
    Arch Pathol Lab Med 133:781-6. 2009
    ..The number of lymph nodes recovered and examined in resection specimens has been recently shown to be critical for proper staging and is associated with survival...
  4. doi request reprint Synchronous renal and adrenal masses: an analysis of 80 cases
    Armita Bahrami
    Baylor College of Medicine, Houston, TX, USA
    Ann Diagn Pathol 13:9-15. 2009
    ..Rare unusual combinations of renal and adrenal lesions such as RCC and adrenal histoplasmosis, RCC and adrenal myelolipoma, renal oncocytoma, and adrenal pheochromocytoma are also described...
  5. ncbi request reprint Mucinous tubular and spindle cell carcinoma of kidney is probably a variant of papillary renal cell carcinoma with spindle cell features
    Steven S Shen
    Department of Pathology, The Methodist Hospital and Research Institute, Houston, TX 77030, USA
    Ann Diagn Pathol 11:13-21. 2007
    ....
  6. doi request reprint PAX-2 is a helpful marker for diagnosing metastatic renal cell carcinoma: comparison with the renal cell carcinoma marker antigen and kidney-specific cadherin
    Ayhan Ozcan
    Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Arch Pathol Lab Med 134:1121-9. 2010
    ..The diagnosis of metastatic renal cell carcinoma (RCC) remains problematic...
  7. doi request reprint Reappraisal of T3N0/NxM0 renal cell carcinoma: significance of extent of fat invasion, renal vein invasion, and adrenal invasion
    Soo Jin Jung
    Department of Pathology, The Methodist Hospital and Research Institute, and Weill Medical College of Cornell University, Houston, TX 77030, USA
    Hum Pathol 39:1689-94. 2008
    ..In contrast, tumors with adrenal gland invasion carry a far worse prognosis than perinephric fat or renal vein invasion and thus supporting a separate stage category...
  8. doi request reprint PAX-2 expression in non-neoplastic, primary neoplastic, and metastatic neoplastic tissue: A comprehensive immunohistochemical study
    Qihui Jim Zhai
    Departments of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Appl Immunohistochem Mol Morphol 18:323-32. 2010
    ..PAX-2 is a sensitive and specific marker for tumors of renal or Müllerian origin in both primary and metastatic contexts...
  9. ncbi request reprint Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma
    Victor G Prieto
    Department of Pathology, The University of Texas M D Anderson Cancer Center, The Methodist Hospital, Houston 77030, USA
    Clin Cancer Res 12:6709-15. 2006
    ....
  10. doi request reprint Muscularis mucosae versus muscularis propria in gallbladder, cystic duct, and common bile duct: smoothelin and desmin immunohistochemical study
    Kirtee Raparia
    Department of Pathology, The Methodist Hospital, Weill Medical College, Cornell University, Houston, TX 77030, USA
    Ann Diagn Pathol 14:408-12. 2010
    ..Differentiating these anatomical muscle structures may be important for the pathologic staging of carcinoma in these organs...
  11. doi request reprint Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modality
    Hyun Jung Kim
    The Methodist Hospital Research Institute, Houston, TX, USA
    Am J Surg Pathol 33:1276-86. 2009
    ..We consider that this technique is a feasible and practical approach for resolving difficult-to-diagnose renal tumors in clinical practice...
  12. doi request reprint PAX2 and PAX8 expression in primary and metastatic renal tumors: a comprehensive comparison
    Ayhan Ozcan
    Department of Pathology, The Methodist Hospital, Houston, Texas, USA
    Arch Pathol Lab Med 136:1541-51. 2012
    ..The diagnosis of renal cell carcinoma (RCC) remains problematic, especially in the context of metastasis or small-needle biopsies. PAX2 and PAX8 transcription factors are known to be expressed by several histologic types of renal neoplasms...
  13. doi request reprint PAX 8 expression in non-neoplastic tissues, primary tumors, and metastatic tumors: a comprehensive immunohistochemical study
    Ayhan Ozcan
    Departments of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Mod Pathol 24:751-64. 2011
    ..This tissue/cell-specific expression is maintained during both neoplastic transformation and metastasis. PAX 8 is a sensitive and specific marker for tumors of renal, Müllerian, or thyroid origin in both primary and metastatic sites...
  14. doi request reprint Lymphovascular invasion in micropapillary urothelial carcinoma: a study of 22 cases
    Elizabeth McQuitty
    Department of Pathology and Genomic Medicine, The Methodist Hospital, 6565 Fannin Street, Houston, TX 77030, USA
    Arch Pathol Lab Med 136:635-9. 2012
    ..Micropapillary urothelial carcinoma (MPUC) is a known aggressive variant of urothelial carcinoma. However, the reasons for its aggressiveness remain unclear...
  15. doi request reprint Diagnosing nonneoplastic lesions in nephrectomy specimens
    Luan D Truong
    Department of Pathology, The Methodist Hospital and Research Institute, 6565 Fannin Street, Houston, TX 77030, USA
    Arch Pathol Lab Med 133:189-200. 2009
    ....
  16. doi request reprint Expression of Galectin-3 in renal neoplasms: a diagnostic, possible prognostic marker
    Jane Y Dancer
    Department of Pathology, The Methodist Hospital and Research Institute and Weill Medical College of Cornell University, Houston, Texas, USA
    Arch Pathol Lab Med 134:90-4. 2010
    ..Galectin-3, a member of the lectin family, was shown to be expressed in normal distal tubular cells and in renal cell carcinomas (RCC). However, its diagnostic and prognostic significance in RCC is as yet undefined...
  17. doi request reprint Plasmacytoid transitional cell carcinoma of urinary bladder: a clinicopathologic study of 9 cases
    Jae Y Ro
    Department of Pathology, The Methodist Hospital and Weill Medical College of Cornell University, Houston, TX 77030, USA
    Am J Surg Pathol 32:752-7. 2008
    ..Morphologic recognition and distinction from other plasmacytoid malignant neoplasms is critical for its clinical management and immunohistochemical studies may be required for differential diagnosis...
  18. doi request reprint Mixed epithelial and stromal tumor of kidney with malignant transformation: report of two cases and review of literature
    Soo Jin Jung
    Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    Hum Pathol 39:463-8. 2008
    ..We report 2 additional cases of sarcomatous transformation in mixed epithelial and stromal tumor of the kidney...
  19. ncbi request reprint Colorectal adenocarcinoma with micropapillary pattern and its association with lymph node metastasis
    Bisong Haupt
    Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Mod Pathol 20:729-33. 2007
    ..311). Multivariate regression analysis demonstrated that the presence of micropapillary component, as well as tumor stage and lymphovascular invasion are independent predictors of regional nodal metastasis...
  20. doi request reprint Mixed epithelial and stromal tumors of the kidney: evidence for a single cell of origin with capacity for epithelial and stromal differentiation
    Jennifer Bup Jong Kum
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 35:1114-22. 2011
    ..Our data support the theory that the stroma and epithelium arise from a common cell of origin...
  21. doi request reprint Intraluminal polypoid metastasis of renal cell carcinoma in gallbladder mimicking gallbladder polyp
    Xueping Fang
    Department of Pathology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Arch Pathol Lab Med 134:1003-9. 2010
    ..Metastatic renal cell carcinoma (RCC) in gallbladder is rare with only 18 cases published in the English literature...
  22. ncbi request reprint Prostatic transitional cell carcinoma: pathologic features and clinical management
    Steven S Shen
    Department of Pathology, The Methodist Hospital and Weill Medical College of Cornell University, 6565 Fannin Street, Houston, TX 77030, USA
    Expert Rev Anticancer Ther 7:1155-62. 2007
    ..A rational approach for management of pTCC in patients with bladder cancer will be proposed on the basis of our experience and our review of literature...
  23. doi request reprint Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologists
    Ankur R Sangoi
    Department of Pathology, Stanford University, Stanford, CA, USA
    Am J Surg Pathol 34:1367-76. 2010
    ..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy...
  24. doi request reprint Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinoma
    Gladell P Paner
    Department of Pathology, Urology, Loyola University Medical Center, Maywood, IL, USA
    Am J Surg Pathol 33:91-8. 2009
    ....
  25. ncbi request reprint Recently described and emphasized entities of renal neoplasms
    Steven S Shen
    Department of Pathology, The Methodist Hospital, 6565 Fannin St, Houston, TX 77030, USA
    Arch Pathol Lab Med 131:1234-43. 2007
    ..In addition, rare nonepithelial renal neoplasms are identified and characterized. Familiarity with these entities will help make the most accurate diagnosis and guide the treatment and follow-up of patients with renal neoplasm...
  26. doi request reprint Small cell carcinoma of the kidney: a clinicopathologic study of 14 cases
    Qiusheng Si
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 42:1792-8. 2011
    ..The frequent coexistence of small cell carcinoma with urothelial carcinoma suggests that renal small cell carcinomas may evolve from a preexisting urothelial carcinoma...
  27. ncbi request reprint Calcium oxalate deposition in renal cell carcinoma associated with acquired cystic kidney disease: a comprehensive study
    Norbert Sule
    Department of Pathology, Renal Section, Baylor College of Medicine, Houston, TX, USA
    Am J Surg Pathol 29:443-51. 2005
    ..Proximal tubular cell differentiation in conjunction with ESRD-mediated high serum level may be pathogenetically important for intratumoral CaOx deposition. These RCCs seems to have a relatively good prognosis...
  28. doi request reprint Immunohistochemical diagnosis of renal neoplasms
    Luan D Truong
    Department of Pathology, The Methodist Hospital, 6565 Fannin St, Houston, TX 77030, USA
    Arch Pathol Lab Med 135:92-109. 2011
    ....
  29. ncbi request reprint Expression of GLUT1 in primary renal tumors: morphologic and biologic implications
    Ayhan Ozcan
    Department of Pathology, Methodist Hospital, Houston, TX 77030, USA
    Am J Clin Pathol 128:245-54. 2007
    ..GLUT1 may be a novel target for immunotherapy and a useful marker in the differential diagnosis and classification of renal tumors...
  30. ncbi request reprint Lymphoid cell proliferation in renal transplants: biologic and diagnostic implications
    Hulya Akgun
    Department of Pathology, The Methodist Hospital, Houston, TX, USA
    Clin Transplant 21:472-80. 2007
    ..Proliferation of IIC involves predominantly T lymphocytes. These observations provide support for the concept of in situ alloimmunization, and facilitate the diagnosis of ACR...
  31. ncbi request reprint Muscularis mucosae of the urinary bladder revisited with emphasis on its hyperplastic patterns: a study of a large series of cystectomy specimens
    Funda Vakar-Lopez
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Ann Diagn Pathol 11:395-401. 2007
    ..Pathologists should be aware of its occurrence and morphologic patterns to accurately assess the depth of invasion of bladder tumors and avoid misinterpreting HMM as the muscularis propria...
  32. doi request reprint Immunohistochemical analysis in a morphologic spectrum of urachal epithelial neoplasms: diagnostic implications and pitfalls
    Gladell P Paner
    Department of Pathology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Am J Surg Pathol 35:787-98. 2011
    ..Knowledge of the similarity in immunostaining to its different morphologic mimics may help avoid misdiagnosis in urachal adenocarcinoma...
  33. doi request reprint Flat pattern of nephrogenic adenoma: previously unrecognized pattern unveiled using PAX2 and PAX8 immunohistochemistry
    Sergio Piña-Oviedo
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, TX 77030, USA
    Mod Pathol 26:792-8. 2013
    ..Immunostains for PAX2 and PAX8 are useful in the detection of nephrogenic adenomas and particularly unveil those nephrogenic adenomas with flat pattern...
  34. doi request reprint Melan A (A103) is not a marker of mesothelioma
    Nelson G Ordonez
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Appl Immunohistochem Mol Morphol 21:181-4. 2013
    ..The possible cause of the discrepancies between the results obtained in the present investigation and those of the initial study is discussed...
  35. ncbi request reprint Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms
    Steven S Shen
    Department of Pathology, The Methodist Hospital, Baylor College of Medicine, Houston, TX 77030, USA
    Mod Pathol 18:933-40. 2005
    ..These results demonstrated high sensitivity and specificity of Ksp-cadherin for distal convoluted tubules, which can be used as adjunct for diagnosis of chromophobe RCC...
  36. doi request reprint Useful immunohistochemical markers in differentiating hemangioblastoma versus metastatic renal cell carcinoma
    Andreana L Rivera
    Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, USA
    Neuropathology 30:580-5. 2010
    ..Fli-1 failed to stain tumor cells in both HBs and RCC. Inhibin A, in combination with PAX-2, showed to be the most useful markers to differentiate HB from metastatic RCC...
  37. doi request reprint Optical coherence tomography as an adjunct to white light cystoscopy for intravesical real-time imaging and staging of bladder cancer
    Alvin C Goh
    Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030 2706, USA
    Urology 72:133-7. 2008
    ..The purpose of this study was to examine the application of OCT in augmenting the diagnosis and staging of bladder lesions...
  38. doi request reprint Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma: evaluation of 1674 cases by tissue microarray
    Bradley M Turner
    Department of Pathology, University of Texas Health Science Center, San Antonio, USA
    Arch Pathol Lab Med 136:163-71. 2012
    ..TTF-1 is a favored marker for lung ACA but has limited sensitivity and specificity. Napsin A (Nap-A) is a functional aspartic proteinase that may be an alternative marker for primary lung ACA...
  39. ncbi request reprint Intraoperative pathology consultation for kidney and urinary bladder specimens
    Luan D Truong
    Department of Pathology, The Methodist Hospital, Baylor College of Medicine, Houston, Texas, USA
    Arch Pathol Lab Med 129:1585-601. 2005
    ..Intraoperative pathology consultation for kidney and urinary bladder specimens is relatively infrequent. Scant literature is devoted to this topic...
  40. doi request reprint Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model
    Guru Sonpavde
    Texas Oncology, P A and U S Oncology Research, Houston, TX 77030, USA
    Urol Oncol 27:391-9. 2009
    ..Angiogenesis and VEGF expression correlate with poor outcomes in human urothelial carcinoma. We designed a preclinical study to examine the efficacy of sunitinib alone and in combination with cisplatin against human urothelial carcinoma...
  41. doi request reprint Interstitial cystitis: another IgG4-related inflammatory disease?
    Suzanne Crumley
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, TX
    Ann Diagn Pathol 17:403-7. 2013
    ..We propose that a subset of patients with IC may have an IgG4-related disease, and further study including serum IgG4 measurement is required to better define this relationship. ..
  42. ncbi request reprint Renal cystic neoplasms and renal neoplasms associated with cystic renal diseases: pathogenetic and molecular links
    Luan D Truong
    Departments of Pathology, Baylor College of Medicine, The Methodist Hospital, Houston, Texas 77030, U S A
    Adv Anat Pathol 10:135-59. 2003
    ..This article reviews the differential diagnoses among cystic neoplasms. It also focuses on the underlying genetic and molecular mechanisms for the relationship between cystic renal diseases and renal neoplasms...
  43. ncbi request reprint Prostatic involvement by transitional cell carcinoma in patients with bladder cancer and its prognostic significance
    Steven S Shen
    Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Hum Pathol 37:726-34. 2006
    ..In summary, presence of prostatic TCC involvement and levels of involvement are significant prognostic factors in patients with bladder cancer...
  44. ncbi request reprint Granulomatous pyelitis associated with urinary obstruction: a comprehensive clinicopathologic study
    Gulfiliz Gonlusen
    Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    Mod Pathol 19:1130-8. 2006
    ..Awareness of this entity and its characteristic clinicopathologic features also helps eliminate an infectious etiology with obvious treatment and prognostic implications...
  45. ncbi request reprint Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms
    Michael L Cohn
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 32:533-6. 2005
    ..Cohn ML, Goncharuk VN, Diwan AH, Zhang PS, Shen SS, Prieto VG. Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms...
  46. ncbi request reprint Invasive ductal carcinoma of the breast with a microglandular adenosis pattern
    Steven S Shen
    Department of Pathology, The Methodist Hospital and Baylor College of Medicine, Houston, TX, USA
    Ann Diagn Pathol 8:39-42. 2004
    ..We report a case of a 64-year-old woman with breast carcinoma of no special type with areas having features with resemblance to microglandular adenosis. Differential diagnosis and their histologic features are discussed...