E Shemesh

..There are also no published data about the age of transition at which a child assumes responsibility over taking the medications. This information is important if interventions to improve adherence are contemplated...

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..This adherence--improvement intervention appears to be promising in improving outcomes in pediatric liver transplant recipients. Larger, controlled studies are needed to establish the efficacy of this or other approaches...

..The study assessed the relationship between a history of child abuse, nonadherence to medications, and medical outcome in children who had a liver transplant...

..Traumatized patients, according to this hypothesis, will avoid taking their medications, because these serve as painful reminders of the disease...

..Understanding the issues involved in screening and diagnosis and the risks and benefits of available treatments can lead to an informed approach to the management of these disorders in the palliative care setting...

..Suggestions are offered for how to improve QoL and reduce distress on the way to better coping with food allergy...

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..In medical care settings, mental health symptoms of depression and distress are associated with poor medical outcomes, yet they are often underrecognized...

..Nonadherence is associated with PTSD symptoms, which may either be a marker for or a cause of nonadherence. Treatment of PTSD may prove to be a useful approach for improving adherence...

..We conducted a study that sought to determine whether PTSD symptoms post-MI are associated with increased likelihood of cardiovascular readmission and with nonadherence to treatment recommendations...

..We hope that the presented program will inspire clinicians in the community and other programs to regard the assessment and improvement of adherence to medications as an important goal in the management of children who had a transplant...

..The child's report of his or her emotional symptoms should be directly sought post-transplant...

..Because many questions remain unanswered (or the answers are not definitive yet), we concisely summarize the issues and present our own view of the most pressing questions for further research...

..This study evaluated discrepancies in parental versus child reports of the child's emotional trauma symptoms in pediatric medical care settings...

..Because treatment of depression in medically ill children may well lead to improvement in medical and psychiatric outcome, there is pressing need for the careful study of potential treatment options in this specific group of patients...

..A randomized, controlled study with a substantial number of enrolled patients is needed to establish the efficacy of this or other approaches...

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..Larger, prospective investigations of the transition process are necessary before recommendations are made regarding interventions...

..In conclusion, the U-PTSD-I performs better among general trauma versus medically ill patients. Intrusion symptoms should be focused on when assessing PTSD in medically ill children...

..PTSD may be a treatable risk factor for poor post-MI outcome. Further research is needed to evaluate treatment options...

..d. of routine tacrolimus blood levels in pediatric liver transplant recipients for detecting non-adherence to immunosuppressant medication prior to clinical rejection, allowing earlier interventions...

..Determining which of these factors predicts poor outcome would inform potential intervention strategies...

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..Pediatric caregivers increasingly recognize their therapeutic role when curative therapy is no longer possible is as pivotal as in the setting of acute illness...

..To evaluate the safety, tolerability, and benefit of fluvoxamine for the treatment of major depressive disorder or anxiety disorders in children and adolescents with cancer...

..The authors conclude with a description of the challenges and promise of an effort to implement a clinical program to screen for PTSD symptoms in patients with cardiovascular illnesses, and with recommendations for future efforts...

..The results will help transplant centers identify these children and improve overall post transplant survival, and will also inform other areas of medicine in which children may not take their medications as prescribed. ..

..This proposal will therefore allow the principal investigator to develop into an independent investigator performing clinical research into the phenomenology and treatment of co-morbid psychiatric and medical illness in children. ..

..We will evaluate the safety as well as the potential benefits of this approach. A full efficacy trial is expected to follow this pilot study if the results are encouraging. ..