R E Seymour
Affiliation: The Jackson Laboratory
- Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitisR E Seymour
The Jackson Laboratory, Bar Harbor, ME 04609, USA
Genes Immun 8:416-21. 2007..These are the first examples of disease-causing mutations in the Sharpin gene and demonstrate the importance of SHARPIN protein in normal immune development and control of inflammation...
- Novel Gene Control of Lymphoid Tissue DevelopmentRosemarie Seymour; Fiscal Year: 2007..Significance: These studies will provide new insight into the unique developmental requirements for Peyer's patches and better understanding of the relationship between lymphoid organization and function. ..