J A Schwartzbaum

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Hypotheses concerning roles of dietary energy, cured meat, and serum tocopherols in adult glioma development
    J A Schwartzbaum
    The Ohio State University, College of Medicine and Public Health, and Comprehensive Cancer Center, Columbus, Ohio 43210, USA
    Neuroepidemiology 18:156-66. 1999
  2. ncbi request reprint An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk
    Judith A Schwartzbaum
    Division of Epidemiology, School of Public Health, Ohio State University, Starling Loving Hall, 320 West Tenth Avenue, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 16:2448-54. 2007
  3. ncbi request reprint Cohort study of cancer risk among male and female shift workers
    Judith Schwartzbaum
    Ohio State University, School of Public Health, Division of Epidemiology and Biometrics, Starling Loving Hall, 320 W Tenth Ave, Columbus, Ohio 43210, USA
    Scand J Work Environ Health 33:336-43. 2007
  4. ncbi request reprint An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors
    Judith A Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Ohio State University, Starling Loving Hall, 320 W Tenth Avenue, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 16:559-65. 2007
  5. pmc Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma
    Judith A Schwartzbaum
    School of Public Health, Division of Epidemiology, Ohio State University, Columbus, Ohio 43210, USA
    Neuro Oncol 12:320-7. 2010
  6. pmc Polymorphisms associated with asthma are inversely related to glioblastoma multiforme
    Judith Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Ohio State University, Columbus, Ohio 43210, USA
    Cancer Res 65:6459-65. 2005
  7. ncbi request reprint Prior hospitalization for epilepsy, diabetes, and stroke and subsequent glioma and meningioma risk
    Judith Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Ohio State University, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 14:643-50. 2005
  8. ncbi request reprint Presurgical serum albumin levels predict survival time from glioblastoma multiforme
    J A Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Comprehensive Cancer Center, The Ohio State University, Columbus 43210, USA
    J Neurooncol 43:35-41. 1999
  9. ncbi request reprint Berkson's bias reviewed
    Judith Schwartzbaum
    Division of Epidemiology, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Eur J Epidemiol 18:1109-12. 2003
  10. ncbi request reprint Cohort studies of association between self-reported allergic conditions, immune-related diagnoses and glioma and meningioma risk
    Judith Schwartzbaum
    Division of Epidemiology, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 106:423-8. 2003

Research Grants

  1. Allergic Condition Biomarkers and Glioma Risk
    Judith Schwartzbaum; Fiscal Year: 2004
  2. Allergic Condition Susceptibility Polymorphisms and Glioma Risk
    Judith Schwartzbaum; Fiscal Year: 2009
  3. Allergic Condition Susceptibility Polymorphisms and Glioma Risk
    Judith Schwartzbaum; Fiscal Year: 2010

Detail Information

Publications23

  1. ncbi request reprint Hypotheses concerning roles of dietary energy, cured meat, and serum tocopherols in adult glioma development
    J A Schwartzbaum
    The Ohio State University, College of Medicine and Public Health, and Comprehensive Cancer Center, Columbus, Ohio 43210, USA
    Neuroepidemiology 18:156-66. 1999
    ..While the observed interaction is predicted by experimental research, our findings are based on small numbers. Larger studies are needed to further evaluate our preliminary findings...
  2. ncbi request reprint An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk
    Judith A Schwartzbaum
    Division of Epidemiology, School of Public Health, Ohio State University, Starling Loving Hall, 320 West Tenth Avenue, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 16:2448-54. 2007
    ..Nonetheless, the association between the T-G IL-4Ralpha haplotype and glioblastoma risk may indicate a role of immune factors in glioblastoma development...
  3. ncbi request reprint Cohort study of cancer risk among male and female shift workers
    Judith Schwartzbaum
    Ohio State University, School of Public Health, Division of Epidemiology and Biometrics, Starling Loving Hall, 320 W Tenth Ave, Columbus, Ohio 43210, USA
    Scand J Work Environ Health 33:336-43. 2007
    ..The present study was conducted to see whether these previous findings could be confirmed and whether shift workers are at elevated risk for cancer at additional sites...
  4. ncbi request reprint An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors
    Judith A Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Ohio State University, Starling Loving Hall, 320 W Tenth Avenue, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 16:559-65. 2007
    ..Because there is less previous evidence for a role of NQO1, CYP1A1, GSTM1, and GSTT1 variants, we restricted analysis of these variants to a small preliminary study...
  5. pmc Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma
    Judith A Schwartzbaum
    School of Public Health, Division of Epidemiology, Ohio State University, Columbus, Ohio 43210, USA
    Neuro Oncol 12:320-7. 2010
    ..However, IL-17 and NCAM-1 may play proinflammatory and immunosuppressive roles, respectively, during the late stage of glioblastoma progression. Our findings suggest that immune function continues to change as the tumor progresses...
  6. pmc Polymorphisms associated with asthma are inversely related to glioblastoma multiforme
    Judith Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Ohio State University, Columbus, Ohio 43210, USA
    Cancer Res 65:6459-65. 2005
    ..However, our findings are also consistent with associations between IL-4RA, IL-13, and GBM that are independent of their role in allergic conditions...
  7. ncbi request reprint Prior hospitalization for epilepsy, diabetes, and stroke and subsequent glioma and meningioma risk
    Judith Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Ohio State University, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 14:643-50. 2005
    ..The occurrence of excess epilepsy > or =8 years before HGG diagnosis suggests a relatively long preclinical phase, but excess diabetes or stroke appear late in HGG development...
  8. ncbi request reprint Presurgical serum albumin levels predict survival time from glioblastoma multiforme
    J A Schwartzbaum
    Division of Epidemiology and Biometrics, School of Public Health, Comprehensive Cancer Center, The Ohio State University, Columbus 43210, USA
    J Neurooncol 43:35-41. 1999
    ..Our findings are consistent with results seen for tumors at other sites. We speculate that our results may be attributable to an association between low serum albumin levels and physiological events associated with angiogenesis...
  9. ncbi request reprint Berkson's bias reviewed
    Judith Schwartzbaum
    Division of Epidemiology, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Eur J Epidemiol 18:1109-12. 2003
  10. ncbi request reprint Cohort studies of association between self-reported allergic conditions, immune-related diagnoses and glioma and meningioma risk
    Judith Schwartzbaum
    Division of Epidemiology, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 106:423-8. 2003
    ..In Cohort III, immune-related discharge diagnoses are also inversely associated with glioma (HR = 0.46; 95% CI = 0.14-1.49). There is no strong evidence against (and some for) the hypothesis that allergies reduce glioma risk...
  11. ncbi request reprint Allergic conditions and brain tumor risk
    Annette Wigertz
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 166:941-50. 2007
    ..60, 0.91). Our results show a reduced risk for glioma associated primarily with current allergic conditions. If this is etiologic, it has implications for the understanding of how allergic conditions might reduce the tumor risk...
  12. ncbi request reprint Depression as an antecedent to heart disease among women and men in the NHANES I study. National Health and Nutrition Examination Survey
    A K Ferketich
    Division of Epidemiology and Biometrics, The Ohio State University College of Medicine and Public Health, Columbus 43210, USA
    Arch Intern Med 160:1261-8. 2000
    ..The present investigation was conducted to evaluate the differential effect depression may have on CHD incidence and mortality in women and men...
  13. pmc Allergic conditions and risk of hematological malignancies in adults: a cohort study
    Karin C Söderberg
    The Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    BMC Public Health 4:51. 2004
    ..This relationship has been studied in several case-control studies, but only in a few cohort studies...
  14. ncbi request reprint Occupational noise exposure and risk of acoustic neuroma
    Colin G Edwards
    Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH 43210, USA
    Am J Epidemiol 166:1252-8. 2007
    ..The effect of nondifferential misclassification of exposure must be considered a potential cause of the negative findings...
  15. ncbi request reprint Comorbidity among the morbidly obese: a comparative study of 2002 U.S. hospital patient discharges
    Susanne K Scott
    Division of Epidemiology, School of Public Health, The Ohio State University, Columbus, Ohio 43210, USA
    Surg Obes Relat Dis 2:105-11. 2006
    ..This study compares demographic characteristics and selected comorbid conditions of morbidly obese patients discharged after surgical obesity procedures and morbidly obese patients discharged after all other hospital procedures...
  16. ncbi request reprint Epidemiology and molecular pathology of glioma
    Judith A Schwartzbaum
    Ohio State University, Columbus, OH 432 10, USA
    Nat Clin Pract Neurol 2:494-503; quiz 1 p following 516. 2006
    ..The Brain Tumor Epidemiology Consortium has been formed to co-ordinate these studies...
  17. ncbi request reprint Case-control study of use of nonsteroidal antiinflammatory drugs and glioblastoma multiforme
    Niccole R Sivak-Sears
    Division of Epidemiology and Biometrics, School of Public Health, College of Medicine and Public Health, Ohio State University, Columbus, OH, USA
    Am J Epidemiol 159:1131-9. 2004
    ..These findings show an inverse association between NSAID use and GBM. Further studies are warranted to determine whether NSAIDs might be effective in the inhibition of GBM development or progression...
  18. ncbi request reprint Exposure to loud noise and risk of acoustic neuroma
    Colin G Edwards
    Division of Epidemiology, School of Public Health, The Ohio State University, Starling Loving Hall Rm A446, 320 West Tenth Avenue, Columbus, OH 43210, USA
    Am J Epidemiol 163:327-33. 2006
    ..12 (95% CI: 1.40, 3.20). The findings of an increased risk of acoustic neuroma with loud noise exposure support previous research...
  19. pmc Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium
    Melissa L Bondy
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:1953-68. 2008
    ..In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address...
  20. ncbi request reprint Evaluation of epidemiologic evidence for primary adult brain tumor risk factors using evidence-based medicine
    James L Fisher
    The Arthur G James Cancer Hospital and Richard J Solove Research Institute, Columbus, Ohio 43221, USA
    Prog Neurol Surg 19:54-79. 2006
    ..Our knowledge of the causes of adult brain tumors is limited and should be expanded by results from large, well-designed studies of novel potential risk factors and potential interactions between known and suspected risk factors...
  21. ncbi request reprint The molecular epidemiology of gliomas in adults
    Margaret Wrensch
    Department of Neurological Surgery, University of California, San Francisco, California 94102, USA
    Neurosurg Focus 19:E5. 2005
    ..Improving survival rates for patients harboring astrocytic tumors will probably require many randomized clinical trials of novel treatment strategies...
  22. ncbi request reprint Epidemiology of brain tumors
    James L Fisher
    The Arthur G James Cancer Hospital and Richard J Solove Research Institute, 2050 Kenny Road, Suite 940, Columbus, Ohio 43221, USA
    Neurol Clin 25:867-90, vii. 2007
    ..New concepts in brain tumor etiology and clinical management are the goal of research, with an aim at eradicating this devastating disease...
  23. ncbi request reprint Gliomas and venous thromboembolism: how common?
    E Antonio Chiocca
    J Neurosurg 106:599-600; discussion 600. 2007

Research Grants4

  1. Allergic Condition Biomarkers and Glioma Risk
    Judith Schwartzbaum; Fiscal Year: 2004
    ..Assuming a 0.05 significance level and 80 percent power, depending on the polymorphism, the proposed sample is large enough to detect a confounding-adjusted odds ratios of 0.6. ..
  2. Allergic Condition Susceptibility Polymorphisms and Glioma Risk
    Judith Schwartzbaum; Fiscal Year: 2009
    ..Second, it will determine whether treatment for allergies blocks their natural glioma- preventing properties. This second point has application to the large number of people who use medication to treat their allergies. ..
  3. Allergic Condition Susceptibility Polymorphisms and Glioma Risk
    Judith Schwartzbaum; Fiscal Year: 2010
    ..Data will be analyzed using logistic and Cox Proportional Hazards Regression, random forests, Bayesian Networks, and software to identify immune-related pathways to Public Health. ..