G A Schwarting

Summary

Affiliation: The Shriver Center
Country: USA

Publications

  1. ncbi request reprint Semaphorin 3A is required for guidance of olfactory axons in mice
    G A Schwarting
    The Shriver Center, Waltham, Massachusetts 02452, USA
    J Neurosci 20:7691-7. 2000
  2. ncbi request reprint Expression of gamma-aminobutyric acid and gonadotropin-releasing hormone during neuronal migration through the olfactory system
    S A Tobet
    The Shriver Center, Harvard Medical School, Program in Neuroscience, Waltham, Massachusetts 02254, USA
    Endocrinology 137:5415-20. 1996
  3. ncbi request reprint Effects of gamma-aminobutyric acid(A) receptor manipulation on migrating gonadotropin-releasing hormone neurons through the entire migratory route in vivo and in vitro
    E P Bless
    Eunice Kennedy Shriver Center, Division of Biomedical Sciences, Waltham, Massachusetts 02452, USA
    Endocrinology 141:1254-62. 2000
  4. ncbi request reprint Deleted in colorectal cancer (DCC) regulates the migration of luteinizing hormone-releasing hormone neurons to the basal forebrain
    G A Schwarting
    The Shriver Center, Waltham, Massachusetts 02452, USA
    J Neurosci 21:911-9. 2001
  5. ncbi request reprint Developmental aspect of the gonadotropin-releasing hormone system
    S A Tobet
    Program in Neuroscience, The Shriver Center, School of Medicine, The University of Massachusetts, 200 Trapelo Road, Waltham, MA 02452, USA
    Mol Cell Endocrinol 185:173-84. 2001
  6. ncbi request reprint Lactosamine differentially affects olfactory sensory neuron projections to the olfactory bulb
    Gerald A Schwarting
    Shriver Center, Waltham, Massachusetts 02452, USA
    Dev Neurobiol 67:1627-40. 2007
  7. ncbi request reprint Lactosamine modulates the rate of migration of GnRH neurons during mouse development
    Elizabeth Bless
    Curis Inc, Cambridge, MA 02138, USA
    Eur J Neurosci 24:654-60. 2006
  8. ncbi request reprint Semaphorin 3A-mediated axon guidance regulates convergence and targeting of P2 odorant receptor axons
    Gerald A Schwarting
    The Shriver Center, 200 Trapelo Road, Waltham, MA 02452, USA
    Eur J Neurosci 19:1800-10. 2004
  9. ncbi request reprint Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons
    Timothy R Henion
    Shriver Center, Waltham, Massachusetts 02452, USA
    J Neurosci 25:1894-903. 2005
  10. ncbi request reprint Minireview: recent progress in gonadotropin-releasing hormone neuronal migration
    Stuart A Tobet
    Colorado State University, Department of Biomedical Sciences, 1617 Campus Delivery, Fort Collins, Colorado 80523, USA
    Endocrinology 147:1159-65. 2006

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Semaphorin 3A is required for guidance of olfactory axons in mice
    G A Schwarting
    The Shriver Center, Waltham, Massachusetts 02452, USA
    J Neurosci 20:7691-7. 2000
    ..These observations indicate that Sema3A expression by ensheathing cells plays an important role in guiding olfactory axons into specific compartments of the OB...
  2. ncbi request reprint Expression of gamma-aminobutyric acid and gonadotropin-releasing hormone during neuronal migration through the olfactory system
    S A Tobet
    The Shriver Center, Harvard Medical School, Program in Neuroscience, Waltham, Massachusetts 02254, USA
    Endocrinology 137:5415-20. 1996
    ....
  3. ncbi request reprint Effects of gamma-aminobutyric acid(A) receptor manipulation on migrating gonadotropin-releasing hormone neurons through the entire migratory route in vivo and in vitro
    E P Bless
    Eunice Kennedy Shriver Center, Division of Biomedical Sciences, Waltham, Massachusetts 02452, USA
    Endocrinology 141:1254-62. 2000
    ..These results suggest that GABA's influence on GnRH development changes as the cells move out of the nasal compartment and extend processes toward the median eminence...
  4. ncbi request reprint Deleted in colorectal cancer (DCC) regulates the migration of luteinizing hormone-releasing hormone neurons to the basal forebrain
    G A Schwarting
    The Shriver Center, Waltham, Massachusetts 02452, USA
    J Neurosci 21:911-9. 2001
    ..Loss of DCC function results in the migration of many LHRH neurons to inappropriate destinations...
  5. ncbi request reprint Developmental aspect of the gonadotropin-releasing hormone system
    S A Tobet
    Program in Neuroscience, The Shriver Center, School of Medicine, The University of Massachusetts, 200 Trapelo Road, Waltham, MA 02452, USA
    Mol Cell Endocrinol 185:173-84. 2001
    ..By combining molecular inquiries with genetic models, single cell analyses, and an in vitro migration model, we are beginning to decipher one of the most critical events in the establishment of the reproductive axis...
  6. ncbi request reprint Lactosamine differentially affects olfactory sensory neuron projections to the olfactory bulb
    Gerald A Schwarting
    Shriver Center, Waltham, Massachusetts 02452, USA
    Dev Neurobiol 67:1627-40. 2007
    ..Neurons that are normally lactosamine negative, survive early postnatal degeneration in beta3GnT1-/- mice but extend axons that converge on inappropriate targets in the mutant OB...
  7. ncbi request reprint Lactosamine modulates the rate of migration of GnRH neurons during mouse development
    Elizabeth Bless
    Curis Inc, Cambridge, MA 02138, USA
    Eur J Neurosci 24:654-60. 2006
    ..These results suggest that the loss of lactosamine on a subset of GnRH neurons impeded the rate of migration from the nose to the brain...
  8. ncbi request reprint Semaphorin 3A-mediated axon guidance regulates convergence and targeting of P2 odorant receptor axons
    Gerald A Schwarting
    The Shriver Center, 200 Trapelo Road, Waltham, MA 02452, USA
    Eur J Neurosci 19:1800-10. 2004
    ..Furthermore, Sema3A plays a key role in the convergence of axons expressing the odorant receptor P2 onto their appropriate targets...
  9. ncbi request reprint Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons
    Timothy R Henion
    Shriver Center, Waltham, Massachusetts 02452, USA
    J Neurosci 25:1894-903. 2005
    ..These results reveal an essential role for lactosamine in sensory axon pathfinding and in the formation of OB synaptic connections...
  10. ncbi request reprint Minireview: recent progress in gonadotropin-releasing hormone neuronal migration
    Stuart A Tobet
    Colorado State University, Department of Biomedical Sciences, 1617 Campus Delivery, Fort Collins, Colorado 80523, USA
    Endocrinology 147:1159-65. 2006
    ..It is likely that the multiple external factors converge on selective signal transduction pathways to engage the mechanical mechanisms needed to modulate GnRH neuronal movement and ultimately migration...
  11. ncbi request reprint Stromal cell-derived factor-1 (chemokine C-X-C motif ligand 12) and chemokine C-X-C motif receptor 4 are required for migration of gonadotropin-releasing hormone neurons to the forebrain
    Gerald A Schwarting
    Shriver Center University of Massachusetts Medical Center, Waltham, Massachusetts 02452, USA
    J Neurosci 26:6834-40. 2006
    ..The MM is smaller in CXCR4-/- mice, suggesting that some MM cells also require SDF-1/CXCR4 function for migration and survival...
  12. ncbi request reprint Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons
    Gerald A Schwarting
    The Shriver Center, 200 Trapelo Road, Waltham, MA 02452, USA
    Eur J Neurosci 19:11-20. 2004
    ..Loss of function through a genetic deletion in either Dcc or Ntn1 results in the migration of many LHRH neurons to inappropriate destinations...
  13. ncbi request reprint Olfactory axon guidance: the modified rules
    Gerald A Schwarting
    Shriver Center and Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    J Neurosci Res 86:11-7. 2008
    ..This review focuses attention on these non-OR factors and their roles in olfactory axon guidance...
  14. ncbi request reprint Overexpression of glutamic acid decarboxylase-67 (GAD-67) in gonadotropin-releasing hormone neurons disrupts migratory fate and female reproductive function in mice
    Sabine Heger
    Division of Neuroscience, Oregon National Regional Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    Endocrinology 144:2566-79. 2003
    ..The possibility arises that similar abnormalities in GABA homeostasis may contribute to syndromes of hypothalamic amenorrhea/oligomenorrhea in humans...
  15. ncbi request reprint Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium
    Gerald A Schwarting
    Shriver Center UMMS, 200 Trapelo Road, Waltham, MA 02452, USA
    J Mol Histol 38:543-53. 2007
    ..Taken together, these results further support a role for Notch signaling in the regulation of olfactory neurogenesis and cell diversity...