Hains D, Chen X, Saxena V, Barr Beare E, Flemming W, Easterling R, et al. Carbonic anhydrase 2 deficiency leads to increased pyelonephritis susceptibility. Am J Physiol Renal Physiol. 2014;307:F869-80 pubmed publisher
..Decreased carbonic anhydrase expression results in increased antimicrobial peptide production by cells other than renal intercalated cells, which is not sufficient to prevent infection after a bacterial challenge...
Saxena V, Hains D, Ketz J, Chanley M, Spencer J, Becknell B, et al. Cell specific qRT-PCR of renal epithelial cells reveals a novel innate immune signature in murine collecting duct. Am J Physiol Renal Physiol. 2017;:ajprenal.00512.2016 pubmed publisher
..To our knowledge this is the first report of isolating murine collecting tubule cells and performing targeted analysis for multiple classes of AMPs. ..