Research Topics
Genomes and GenesSpecies | Robert A SchulzSummaryAffiliation: The University of Texas Country: USA Publications
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Detail Information
Publications
U-shaped protein domains required for repression of cardiac gene expression in DrosophilaTsuyoshi Tokusumi
Department of Biochemistry and Molecular Biology, Program in Genes and Development, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Differentiation 75:166-74. 2007..Together, these findings provide molecular insights into the function of U-shaped as a negative regulator of heart development in Drosophila...
Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle developmentRobert A Schulz
Department of Biochemistry and Molecular Biology, Graduate Program in Genes and Development, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Dev Biol 266:1-16. 2004....
CF2 represses Actin 88F gene expression and maintains filament balance during indirect flight muscle development in DrosophilaKathleen M Gajewski
Department of Systems Biology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
PLoS ONE 5:e10713. 2010....
Identification of a crystal cell-specific enhancer of the black cells prophenoloxidase gene in DrosophilaKathleen M Gajewski
Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Genesis 45:200-7. 2007..Thus, Srp and Lz do not just specify the crystal cell lineage, but also regulate the later differentiation of these cells. Additionally, we now have a sensitive tool for marking crystal cells in live animals...
The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in DrosophilaRichard Paul Sorrentino
Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Dev Biol 311:311-23. 2007..Such functions appear to be facilitated through Ush interaction with the hematopoietic GATA factor Serpent (Srp)...
Requirement of the LIM homeodomain transcription factor tailup for normal heart and hematopoietic organ formation in Drosophila melanogasterYe Tao
Department of Biochemistry and Molecular Biology, Unit 1000, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Mol Cell Biol 27:3962-9. 2007..Together, these results establish Tailup as being a critical new transcription factor in dorsal vessel morphogenesis and lymph gland formation and place this regulator directly upstream of Hand in these developmental processes...
Second chromosome genes required for heart development in Drosophila melanogasterYe Tao
Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Genesis 45:607-17. 2007..Several of these sequences have known vertebrate homologues, further supporting a conserved genetic basis for heart formation in Drosophila and higher eukaryotes...
Calcineurin function is required for myofilament formation and troponin I isoform transition in Drosophila indirect flight muscleKathleen M Gajewski
Department of Biochemistry and Molecular Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Dev Biol 289:17-29. 2006..Together, these findings suggest a molecular basis for the indirect flight muscle hypercontractility phenotype observed in flies mutant for Drosophila calcineurin B2...
Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogasterJianbo Wang
Department of Biochemistry and Molecular Biology, Box 117, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Mol Cell Biol 25:4200-10. 2005..Such findings implicate Toll as a critical cell adhesion molecule in the alignment and migration of cardioblasts during dorsal vessel morphogenesis...
GATA factors in Drosophila heart and blood cell developmentRichard Paul Sorrentino
Department of Biochemistry and Molecular Biology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Semin Cell Dev Biol 16:107-16. 2005..We also assess the molecular and genetic characteristics of the Friend of GATA protein U-shaped, which serves as a regulator of Pannier and Serpent function in these two developmental processes...
Heart development in DrosophilaYe Tao
Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Semin Cell Dev Biol 18:3-15. 2007..Emerging genome-based strategies should further facilitate the use of Drosophila as an advantageous system in which to identify previously unknown genes and regulatory networks essential for normal cardiac development and function...
Hemocyte development during Drosophila embryogenesisRobert A Schulz
Department of Biochemistry and Molecular Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
Methods Mol Med 105:109-22. 2005..This is possible through methods described in this chapter on messenger ribonucleic acid localization by in situ hybridization and protein localization by immunohistochemical staining within hemocyte precursors and mature blood cells...
Combinatorial interactions of serpent, lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesisNancy Fossett
Department of Biochemistry and Molecular Biology, Graduate Program in Genes and Development, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Proc Natl Acad Sci U S A 100:11451-6. 2003..These findings provide definitive proof of the combinatorial regulation of hematopoiesis in Drosophila and an in vivo demonstration of GATA and Runx functional interaction in a blood cell commitment program...
Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in DrosophilaKathleen Gajewski
Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Proc Natl Acad Sci U S A 100:1040-5. 2003....
Mutations within the conserved MADS box of the D-MEF2 muscle differentiation factor result in a loss of DNA binding ability and lethality in DrosophilaTrent Nguyen
Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Differentiation 70:438-46. 2002....
Phosphorylation by the DHIPK2 protein kinase modulates the corepressor activity of GrouchoCheol Yong Choi
Laboratory Research Program, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
J Biol Chem 280:21427-36. 2005....
Regulation of Drosophila friend of GATA gene, u-shaped, during hematopoiesis: a direct role for serpent and lozengeSelen Muratoglu
Center for Vascular and Inflammatory Diseases and the Department of Pathology, University of Maryland School of Medicine, 800 W Baltimore Street, Baltimore, MD 21201, USA
Dev Biol 296:561-79. 2006..The results of these studies provide information to analyze further the regulation of this conserved gene family and its role during hematopoietic lineage commitment...
Homeotic genes autonomously specify the anteroposterior subdivision of the Drosophila dorsal vessel into aorta and heartPatrick C H Lo
Brookdale Center for Molecular, Cell and Developmental Biology, Mount Sinai School of Medicine, New York, New York 10029, USA
Dev Biol 251:307-19. 2002....
