K M Schmeler

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Venous thromboembolism (VTE) rates following the implementation of extended duration prophylaxis for patients undergoing surgery for gynecologic malignancies
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 128:204-8. 2013
  2. doi request reprint Preventing cervical cancer globally
    Kathleen M Schmeler
    Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Prev Res (Phila) 5:1257-9. 2012
  3. doi request reprint A phase II study of GM-CSF and rIFN-gamma1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1439, USA
    Gynecol Oncol 113:210-5. 2009
  4. doi request reprint Pelvic fractures after radiotherapy for cervical cancer: implications for survivors
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Cancer 116:625-30. 2010
  5. ncbi request reprint Gynecologic cancers associated with Lynch syndrome/HNPCC
    K M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, USA
    Clin Transl Oncol 10:313-7. 2008
  6. doi request reprint Conservative management of early stage cervical cancer: is there a role for less radical surgery?
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, 1155 Herman Pressler Drive, Houston, TX 77030, USA
    Gynecol Oncol 120:321-5. 2011
  7. doi request reprint Primary peritoneal cancer after bilateral salpingo-oophorectomy in two patients with Lynch syndrome
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Obstet Gynecol 115:432-4. 2010
  8. doi request reprint Low-grade serous primary peritoneal carcinoma
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, 1155 Herman Pressler Drive, Houston, TX 77230, USA
    Gynecol Oncol 121:482-6. 2011
  9. doi request reprint Endometrial cancer in an adolescent: a possible manifestation of Cowden syndrome
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Obstet Gynecol 114:477-9. 2009
  10. ncbi request reprint Adnexal masses in pregnancy: surgery compared with observation
    Kathleen M Schmeler
    Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University Medical School, Providence, Rhode Island, USA
    Obstet Gynecol 105:1098-103. 2005

Detail Information

Publications46

  1. pmc Venous thromboembolism (VTE) rates following the implementation of extended duration prophylaxis for patients undergoing surgery for gynecologic malignancies
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 128:204-8. 2013
    ..To compare the incidence of venous thromboembolism (VTE) before and after the implementation of standardized extended duration prophylaxis guidelines in women undergoing laparotomy for gynecologic cancer...
  2. doi request reprint Preventing cervical cancer globally
    Kathleen M Schmeler
    Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Prev Res (Phila) 5:1257-9. 2012
    ..This perspective reviews the limitations of existing cervical cancer screening methods currently in use in low-resource settings and the potential for HRME imaging to contribute to cervical cancer prevention in the developing world...
  3. doi request reprint A phase II study of GM-CSF and rIFN-gamma1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1439, USA
    Gynecol Oncol 113:210-5. 2009
    ....
  4. doi request reprint Pelvic fractures after radiotherapy for cervical cancer: implications for survivors
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Cancer 116:625-30. 2010
    ..The incidence of pelvic fractures and associated risk factors was determined in women treated with curative-intent radiotherapy for cervical cancer...
  5. ncbi request reprint Gynecologic cancers associated with Lynch syndrome/HNPCC
    K M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, USA
    Clin Transl Oncol 10:313-7. 2008
    ..In addition, risk-reducing surgery consisting of prophylactic hysterectomy and bilateral salpingooophorectomy should be offered to women aged 35 years or older who do not wish to preserve their fertility...
  6. doi request reprint Conservative management of early stage cervical cancer: is there a role for less radical surgery?
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, 1155 Herman Pressler Drive, Houston, TX 77030, USA
    Gynecol Oncol 120:321-5. 2011
    ..The objective of this report is to review the existing literature in this area and to describe an ongoing prospective study evaluating the safety and efficacy of conservative surgery in women with early stage cervical cancer...
  7. doi request reprint Primary peritoneal cancer after bilateral salpingo-oophorectomy in two patients with Lynch syndrome
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Obstet Gynecol 115:432-4. 2010
    ..We describe two cases of primary peritoneal cancer after BSO in women with Lynch syndrome or HNPCC...
  8. doi request reprint Low-grade serous primary peritoneal carcinoma
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, 1155 Herman Pressler Drive, Houston, TX 77230, USA
    Gynecol Oncol 121:482-6. 2011
    ..To further explore this issue, a retrospective analysis of the clinical and pathologic characteristics of women with low-grade serous PPC was performed...
  9. doi request reprint Endometrial cancer in an adolescent: a possible manifestation of Cowden syndrome
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Obstet Gynecol 114:477-9. 2009
    ..Cowden syndrome is an autosomal dominant disorder characterized by the development of multiple intestinal hamartomas, distinctive mucocutaneous lesions, and an increased risk of endometrial, breast, and thyroid cancer...
  10. ncbi request reprint Adnexal masses in pregnancy: surgery compared with observation
    Kathleen M Schmeler
    Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University Medical School, Providence, Rhode Island, USA
    Obstet Gynecol 105:1098-103. 2005
    ..To estimate whether the delay of surgery impacts the risk of adverse maternal and fetal outcomes in patients diagnosed with an adnexal mass during pregnancy...
  11. ncbi request reprint Prevalence of lymph node metastasis in primary mucinous carcinoma of the ovary
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Obstet Gynecol 116:269-73. 2010
    ..To estimate the prevalence of lymph node involvement in women with primary mucinous ovarian carcinomas...
  12. ncbi request reprint Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
    N Engl J Med 354:261-9. 2006
    ..We designed this study to determine the reduction in the risk of gynecologic cancers associated with prophylactic hysterectomy and bilateral salpingo-oophorectomy in women with the Lynch syndrome...
  13. doi request reprint Primary chemoprevention of endometrial hyperplasia with the peroxisome proliferator-activated receptor gamma agonist rosiglitazone in the PTEN heterozygote murine model
    W Wu
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Gynecol Cancer 18:329-38. 2008
    ..8% vs 30.2%; P = 0.003). PPAR-gamma agonist rosiglitazone inhibits proliferation and induces apoptosis in both PTEN intact and PTEN null cancer cell lines and in hyperplastic endometrial lesions in the PTEN(+/)(-)murine model...
  14. ncbi request reprint Loss of phosphatase and tensin homologue deleted on chromosome 10 and phosphorylation of mammalian target of rapamycin are associated with progesterone refractory endometrial hyperplasia
    M R Milam
    Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Int J Gynecol Cancer 18:146-51. 2008
    ..In select cases of non-responsive progesterone refractory EH, a rational target for treatment may involve the mTOR pathway...
  15. doi request reprint Risk of thromboembolic disease in patients undergoing laparoscopic gynecologic surgery
    Alpa M Nick
    Department of Gynecologic Oncology, The University of Texas MD Anderson Medical Cancer Center, Houston, Texas 77030, USA
    Obstet Gynecol 116:956-61. 2010
    ..To estimate the incidence of venous thromboembolism among patients undergoing gynecologic laparoscopy and characterize the risk of venous thromboembolism among patients with gynecologic malignancy...
  16. doi request reprint Unmasking the complexities of mucinous ovarian carcinoma
    Michael Frumovitz
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 117:491-6. 2010
    ..The objective of our review was to identify and synthesize the most current information on mucinous ovarian carcinoma with regard to pathologic, molecular, and clinical distinctions...
  17. doi request reprint Limited utility of magnetic resonance imaging in determining the primary site of disease in patients with inconclusive endometrial biopsy
    Pedro T Ramirez
    Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Int J Gynecol Cancer 20:1344-9. 2010
    ..To evaluate the utility of preoperative magnetic resonance imaging (MRI) in determining whether primary disease site is cervical or endometrial in patients with inconclusive preoperative endometrial biopsy...
  18. doi request reprint Safety and feasibility of robotic radical trachelectomy in patients with early-stage cervical cancer
    Pedro T Ramirez
    Department of Gynecologic Oncology, Unit 440, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 116:512-5. 2010
    ..This study aimed to determine the safety and feasibility of robotic radical trachelectomy and bilateral pelvic lymphadenectomy. We also describe our surgical technique...
  19. doi request reprint Laparoscopic extraperitoneal para-aortic lymphadenectomy in locally advanced cervical cancer: a prospective correlation of surgical findings with positron emission tomography/computed tomography findings
    Pedro T Ramirez
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 117:1928-34. 2011
    ..No previous studies have prospectively compared positron emission tomography (PET)/computed tomography (CT) with laparoscopic extraperitoneal staging in the evaluation of para-aortic lymph nodes...
  20. doi request reprint Parametrial involvement in radical hysterectomy specimens for women with early-stage cervical cancer
    Michael Frumovitz
    Departments of 1Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Obstet Gynecol 114:93-9. 2009
    ....
  21. ncbi request reprint Are women ready for the HPV vaccine?
    Brian M Slomovitz
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 103:151-4. 2006
    ..Because vaccination for both boys and girls will be critical to reduce the incidence of this disease, we evaluated the willingness of women to accept the HPV vaccine and to consent to having their children vaccinated...
  22. doi request reprint Lymphadenectomy during endometrial cancer staging: practice patterns among gynecologic oncologists
    Pamela T Soliman
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, 1155 Herman Pressler CPB 6 3244, Unit 1362, Houston, TX 77030, USA
    Gynecol Oncol 119:291-4. 2010
    ..The purpose of this study was to identify practice patterns among gynecologic oncologists when performing a lymph node evaluation during staging for endometrial cancer...
  23. ncbi request reprint Low-grade serous ovarian cancer: a unique disease
    Kathleen M Schmeler
    Department of Gynecologic Oncology, University of Texas M D Anderson Cancer Center, PO Box 301439, Unit 1362, Houston, TX 77230, USA
    Curr Oncol Rep 10:519-23. 2008
    ..Further study, focusing specifically on low-grade serous carcinomas, is needed to determine the role of other chemotherapeutic agents, hormonal therapy, or targeted biologic agents in the treatment of this disease...
  24. ncbi request reprint Prophylactic bilateral salpingo-oophorectomy compared with surveillance in women with BRCA mutations
    Kathleen M Schmeler
    Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA
    Obstet Gynecol 108:515-20. 2006
    ..The objective of this study was to evaluate clinical factors associated with choosing prophylactic bilateral salpingo-oophorectomy (BSO) over surveillance in women with a BRCA1 or BRCA2 mutation...
  25. ncbi request reprint Neoadjuvant chemotherapy for low-grade serous carcinoma of the ovary or peritoneum
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, 1155 Herman Pressler Drive, Houston, TX 77030, USA
    Gynecol Oncol 108:510-4. 2008
    ..To evaluate the response of women with low-grade serous carcinoma of the ovary or peritoneum to platinum-based neoadjuvant chemotherapy...
  26. doi request reprint Efficacy of letrozole in the treatment of recurrent platinum- and taxane-resistant high-grade cancer of the ovary or peritoneum
    Pedro T Ramirez
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
    Gynecol Oncol 110:56-9. 2008
    ..To evaluate the efficacy and safety of letrozole in patients with recurrent platinum- and taxane-resistant estrogen receptor-positive (ER+) high-grade cancer of the ovary or peritoneum...
  27. doi request reprint Laparoscopic and robotic techniques for radical hysterectomy in patients with early-stage cervical cancer
    Pedro T Ramirez
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1439, USA
    Gynecol Oncol 110:S21-4. 2008
    ..The goal of this review is to summarize the latest literature on the subject of laparoscopic and robotic approaches for radical hysterectomy in patients with early-stage cervical cancer...
  28. doi request reprint Fertility preservation in patients with early cervical cancer: radical trachelectomy
    Pedro T Ramirez
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1439, USA
    Gynecol Oncol 110:S25-8. 2008
    ..The goal of this review is to summarize the latest literature on the subject of radical trachelectomy and fertility outcomes in patients with early-stage cervical cancer...
  29. doi request reprint Robotic radical parametrectomy and pelvic lymphadenectomy in patients with invasive cervical cancer
    Pedro T Ramirez
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1439, USA
    Gynecol Oncol 111:18-21. 2008
    ..The goal of this study is to report on the safety and feasibility of robotic radical parametrectomy...
  30. doi request reprint Limited public knowledge of obesity and endometrial cancer risk: what women know
    Pamela T Soliman
    Department of Gynecologic Oncology, and Division of Quantitative Sciences, University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Obstet Gynecol 112:835-42. 2008
    ..To estimate if women in the general population are aware of the relationship between obesity and cancer risk, and to identify groups who may benefit from educational programs...
  31. doi request reprint Radical hysterectomy in obese and morbidly obese women with cervical cancer
    Michael Frumovitz
    Departments of Gynecologic Oncology and Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Obstet Gynecol 112:899-905. 2008
    ....
  32. ncbi request reprint Risk factors for young premenopausal women with endometrial cancer
    Pamela T Soliman
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Obstet Gynecol 105:575-80. 2005
    ..The objective of this study was to conduct a clinical and pathologic review of endometrial cancers diagnosed in premenopausal women aged younger than 50 years, to better identify the risk factors for this subgroup of women...
  33. ncbi request reprint Women with synchronous primary cancers of the endometrium and ovary: do they have Lynch syndrome?
    Pamela T Soliman
    Department of Gynecologic Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 23:9344-50. 2005
    ..The purpose of our study was to determine the likelihood of MMR defects (MSH2, MSH6, MLH1) in women with synchronous endometrial and ovarian cancer...
  34. doi request reprint Laparoscopy training in gynecologic oncology fellowship programs
    Michael Frumovitz
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 111:197-201. 2008
    ..To assess the adequacy of laparoscopic surgical training as perceived by gynecologic oncology fellows-in-training and to compare current opinions to those on a 2003 survey...
  35. doi request reprint Rate of vaginal cuff separation following laparoscopic or robotic hysterectomy
    Alpa M Nick
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 120:47-51. 2011
    ..The goal of our study was to determine the rate of vaginal cuff separation and associated risk factors in patients undergoing laparoscopic or robotic hysterectomy...
  36. doi request reprint Rate of para-aortic lymph node micrometastasis in patients with locally advanced cervical cancer
    Behrouz Zand
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA
    Gynecol Oncol 119:422-5. 2010
    ..To determine the rate of para-aortic node micrometastasis in patients with locally advanced cervical cancer undergoing laparoscopic extraperitoneal para-aortic lymphadenectomy...
  37. doi request reprint Communication of BRCA1 and BRCA2 genetic test results to health care providers following genetic testing at a tertiary care center
    K Ready
    Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA
    Fam Cancer 10:673-9. 2011
    ..Tertiary care centers should facilitate outreach and education with OHCPs in order to assure appropriate long-term cancer risk management for high risk populations...
  38. ncbi request reprint Endometrial cancer in young, normal-weight women
    Kathleen M Schmeler
    Department of Gynecologic Oncology, The University of Texas, M D Anderson Cancer Center, PO Box 301439, Unit 1362, Houston, TX 77230 1439, USA
    Gynecol Oncol 99:388-92. 2005
    ..To determine if young, normal-weight women with endometrial cancer have unique risk factors and clinical characteristics when compared with young, overweight and obese women with endometrial cancer...
  39. doi request reprint Conservative surgery in early-stage cervical cancer: what percentage of patients may be eligible for conization and lymphadenectomy?
    Ashlee L Smith
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 119:183-6. 2010
    ....
  40. doi request reprint Recurrence patterns and prognosis of endometrial stromal sarcoma and the potential of tyrosine kinase-inhibiting therapy
    X Cheng
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Gynecol Oncol 121:323-7. 2011
    ..Endometrial stromal sarcoma (ESS) is a rare uterine malignancy. The current treatment approaches yield unsatisfactory results, and potential therapeutic targets need exploration...
  41. ncbi request reprint Correlation of cyclin D1 and cyclin D3 overexpression with the loss of PTEN expression in endometrial carcinoma
    W Wu
    Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Int J Gynecol Cancer 16:1668-72. 2006
    ..Overexpression of cyclin D1 is frequent in moderate or high-grade EECs and likely results from multiple mechanisms...
  42. doi request reprint Evaluating women with ovarian cancer for BRCA1 and BRCA2 mutations: missed opportunities
    Larissa A Meyer
    Department of Gynecologic Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Obstet Gynecol 115:945-52. 2010
    ..To estimate the incidence of genetic counseling referral for ovarian cancer patients who are at substantial risk for a BRCA1 or BRCA2 mutation...
  43. ncbi request reprint Association between adiponectin, insulin resistance, and endometrial cancer
    Pamela T Soliman
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Cancer 106:2376-81. 2006
    ..The purpose of the current study was to determine whether there was an independent association between adiponectin level and endometrial cancer...
  44. doi request reprint Anti-angiogenesis therapy with bevacizumab for patients with ovarian granulosa cell tumors
    Xia Tao
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 1439, USA
    Gynecol Oncol 114:431-6. 2009
    ..Ovarian granulosa cell tumors tend to respond poorly to chemotherapy. We examined the clinical efficacy of bevacizumab with or without concurrent chemotherapy and evaluated the angiogenic characteristics of these patients' tumors...
  45. ncbi request reprint Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model
    Michael R Milam
    Department of Gynecologic Oncology, M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Obstet Gynecol 196:247.e1-5. 2007
    ..The objective of this study was to evaluate an oral mTOR inhibitor (mTOR-I) on the reduction of endometrial hyperplasia in an animal model...