Kaoru Saijo

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint Protein kinase Cdelta controls self-antigen-induced B-cell tolerance
    Ingrid Mecklenbrauker
    Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021, USA
    Nature 416:860-5. 2002
  2. pmc Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha
    Kaoru Saijo
    Laboratory of Lymphocyte Signaling, Rockefeller University, New York, NY 10021, USA
    J Exp Med 195:1647-52. 2002
  3. ncbi request reprint Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development
    Kaoru Saijo
    Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, NY 10021, USA
    Nat Immunol 4:274-9. 2003
  4. ncbi request reprint B cell immunity regulated by the protein kinase C family
    Kaoru Saijo
    Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 987:125-34. 2003
  5. ncbi request reprint Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival
    Arnold Han
    Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10021, USA
    Immunity 19:621-32. 2003
  6. ncbi request reprint Selective expansion of human natural killer cells from peripheral blood mononuclear cells by the cell line, HFWT
    Hideki Harada
    RIKEN Cell Bank, RIKEN The Institute of Physical and Chemical Research, Tsukuba Science City 305 0074, Japan
    Jpn J Cancer Res 93:313-9. 2002
  7. ncbi request reprint A Wilms tumor cell line, HFWT, can greatly stimulate proliferation of CD56+ human natural killer cells and their novel precursors in blood mononuclear cells
    Hideki Harada
    RIKEN Cell Bank, RIKEN The Institute of Physical and Chemical Research, Tsukuba Science City, Japan
    Exp Hematol 32:614-21. 2004
  8. ncbi request reprint Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations
    Kazuhiro Sudo
    Cell Engineering Division, RIKEN BioResource Center, Koyadai 3 1 1, Tsukuba, Ibaraki, 305 0074, Japan
    Stem Cells 25:1610-7. 2007

Collaborators

  • Takahiro Adachi
  • I Hsin Su
  • Michael Reth
  • Hajime Karasuyama
  • C A Lowell
  • Hideki Harada
  • Ingrid Mecklenbrauker
  • Kazuhiro Sudo
  • Tadao Ohno
  • Isamu Ishiwata
  • Arnold Han
  • Satoru Watanabe
  • Alexander Tarakhovsky
  • Yukio Nakamura
  • Megumi Kanno
  • Takashi Hiroyama
  • Kenichi Miharada
  • Saeri Ogawa
  • Michel C Nussenzweig
  • Michael Leitges
  • Koji Tsuboi
  • Nai Ying Zheng
  • Tadao Nose

Detail Information

Publications8

  1. ncbi request reprint Protein kinase Cdelta controls self-antigen-induced B-cell tolerance
    Ingrid Mecklenbrauker
    Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021, USA
    Nature 416:860-5. 2002
    ..As deficiency of PKC-delta does not affect BCR-mediated B-cell activation in vitro and in vivo, our data suggest a selective and essential role of PKC-delta in tolerogenic, but not immunogenic, B-cell responses...
  2. pmc Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha
    Kaoru Saijo
    Laboratory of Lymphocyte Signaling, Rockefeller University, New York, NY 10021, USA
    J Exp Med 195:1647-52. 2002
    ....
  3. ncbi request reprint Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development
    Kaoru Saijo
    Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, NY 10021, USA
    Nat Immunol 4:274-9. 2003
    ..Our data show the existence of a functionally distinct SFK signaling module responsible for pre-BCR-mediated NF-kappaB activation and B cell development...
  4. ncbi request reprint B cell immunity regulated by the protein kinase C family
    Kaoru Saijo
    Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 987:125-34. 2003
    ..PKCdelta on the other hand specifically regulates the induction of tolerance in self-reactive B cells. Thus, individual PCKs regulate B cell immunity specifically...
  5. ncbi request reprint Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival
    Arnold Han
    Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10021, USA
    Immunity 19:621-32. 2003
    ....
  6. ncbi request reprint Selective expansion of human natural killer cells from peripheral blood mononuclear cells by the cell line, HFWT
    Hideki Harada
    RIKEN Cell Bank, RIKEN The Institute of Physical and Chemical Research, Tsukuba Science City 305 0074, Japan
    Jpn J Cancer Res 93:313-9. 2002
    ..These results will contribute to the development of a large-scale preparation method for human NK cells, which will aid studies of NK cell biology and possible treatment of brain tumors...
  7. ncbi request reprint A Wilms tumor cell line, HFWT, can greatly stimulate proliferation of CD56+ human natural killer cells and their novel precursors in blood mononuclear cells
    Hideki Harada
    RIKEN Cell Bank, RIKEN The Institute of Physical and Chemical Research, Tsukuba Science City, Japan
    Exp Hematol 32:614-21. 2004
    ..In this study, we attempted to identify NK precursors in PBMC or in cord blood mononuclear cells (CBMC) that preferentially respond to feeder HFWT cells...
  8. ncbi request reprint Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations
    Kazuhiro Sudo
    Cell Engineering Division, RIKEN BioResource Center, Koyadai 3 1 1, Tsukuba, Ibaraki, 305 0074, Japan
    Stem Cells 25:1610-7. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...